A Functional Haplotype of the PADI4 Gene Associated With Rheumatoid Arthritis in a Japanese Population Is Not Associated in a United Kingdom Population

Arthritis and Rheumatism

Volumn 50, Issue 4, 2004, Pages 1117-1121

  Barton, Anne ^a   Bowes, John ^a   Eyre, Stephen ^a   Spreckley, Kristian ^a   Hinks, Anne ^a   John, Sally ^a   Worthington, Jane ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN ARGININE DEIMINASE; PROTEIN ARGININE DEIMINASE 4; UNCLASSIFIED DRUG;

ADULT; ALLELE; ARTICLE; CAUCASIAN; CONTROLLED STUDY; EXON; FEMALE; GENE FREQUENCY; GENE IDENTIFICATION; GENE MAPPING; GENETIC ALGORITHM; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HUMAN; JAPAN; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RACE DIFFERENCE; RHEUMATOID ARTHRITIS; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED KINGDOM;

ADULT; ARTHRITIS, RHEUMATOID; ASIAN CONTINENTAL ANCESTRY GROUP; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GREAT BRITAIN; HAPLOTYPES; HUMANS; HYDROLASES; JAPAN; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 1842733194     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.20169     Document Type: Article

References (17)

1. Symmons D, Turner G, Webb R, Asten P, Barrett E, Lunt M, et al. The prevalence of rheumatoid arthritis in the United Kingdom: new estimates for a new century. Rheumatology (Oxford) 2002;41:793-800.
2. Deighton CM, Walker DJ, Griffiths ID, Roberts DF. The contribution of HLA to rheumatoid arthritis. Clin Genet 1989;136:178-82.
3. Barton A, Ollier W. Genetic approaches to the investigation of rheumatoid arthritis. Curr Opin Rheumatol 2002;14:260-9.
4. Suzuki A, Yamada R, Chang X, Tokuhiro S, Sawada T, Suzuki M, et al. Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis. Nat Genet 2003;34:395-402.
5. Zhou Z, Menard HA. Autoantigenic posttranslational modifications of proteins: does it apply to rheumatoid arthritis? Curr Opin Rheumatol 2002;14:250-3.
6. Cornelis F, Faure S, Martinez M, Prud'homme JF, Fritz P, Dib C, et al. New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study. Proc Natl Acad Sci U S A 1998;95:10746-50.
7. Shiozawa S, Hayashi S, Tsukamoto Y, Goko H, Kawasaki H, Wada T, et al. Identification of the gene loci that predispose to rheumatoid arthritis. Int Immunol 1998;10:1891-5.
8. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
9. MacGregor AJ, Bamder S, Silman AJ. A comparison of the performance of different methods of disease classification for rheumatoid arthritis: results from an analysis from a nationwide twin study. J Rheumatol 1994;21:1420-6.
10. Leal SM, Ott J. Effects of stratification in the analysis of affected-sib-pair data: benefits and costs. Am J Hum Genet 2000;66:567-75.
11. Stephens M, Smith NJ, Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 2001;68:978-89.
12. Sham PC, Curtis D. Monte Carlo tests for associations between disease and alleles at highly polymorphic loci. Ann Hum Genet 1995;59:97-105.
13. Bas S, Genevay S, Meyer O, Gabay C. Anti-cyclic citrullinated peptide antibodies, IgM and IgA rheumatoid factors in the diagnosis and prognosis of rheumatoid arthritis. Rheumatology (Oxford) 2003;42:677-80.
14. Meyer O, Labarre C, Dougados M, Goupille P, Cantagrel A, Dubois A, et al. Anticitrullinated protein/peptide antibody assays in early rheumatoid arthritis for predicting five year radiographic damage. Ann Rheum Dis 2003;62:120-6.
15. Visser H, le Cessie S, Vos K, Breedveld FC, Hazes JM. How to diagnose rheumatoid arthritis early: a prediction model for persistent (erosive) arthritis. Arthritis Rheum 2002;46:357-65.
16. MacKay K, Eyre S, Myerscough A, Milicic A, Barton A, Laval S, et al. Whole genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 United Kingdom affected sibling pairs. Arthritis Rheum 2002;46:632-9.
17. Van Heel DA, McGovern DP, Cardon LR, Dechairo BM, Lench NJ, Carey AH, et al. Fine mapping of the IBD1 locus did not identify Crohn disease-associated NOD2 variants: implications for complex disease genetics. Am J Med Genet 2002;111:253-9.