Cortactin: An Achilles' heel of the actin cytoskeleton targeted by pathogens

Trends in Microbiology

Volumn 13, Issue 4, 2005, Pages 181-189

  Selbach, Matthias ^a   Backert, Steffen ^b  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CORTACTIN;

BACTERIAL INFECTION; CHLAMYDIA; CHLAMYDIA TRACHOMATIS; CRYPTOSPORIDIUM; CYTOSKELETON; DISEASE COURSE; ESCHERICHIA COLI; GENE TARGETING; HELICOBACTER; HELICOBACTER PYLORI; HUMAN; LISTERIA; LISTERIA MONOCYTOGENES; NEISSERIA; NEISSERIA MENINGITIDIS; NONHUMAN; PRIORITY JOURNAL; PROTOZOAL INFECTION; REVIEW; RICKETTSIA; RICKETTSIA CONORII; SHIGELLA; SHIGELLA FLEXNERI; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; VACCINIA VIRUS; VIRUS INFECTION;

CHLAMYDIA; CRYPTOSPORIDIUM; ESCHERICHIA COLI; HELICOBACTER; LISTERIA; NEISSERIA; RICKETTSIA; SHIGELLA; STAPHYLOCOCCUS; VACCINIA; VACCINIA VIRUS;

EID: 16244370694     PISSN: 0966842X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tim.2005.02.007     Document Type: Review

References (70)

1. J.E. Galan, and A. Collmer Type III secretion machines: bacterial devices for protein delivery into host cells Science 284 1999 1322 1328
2. S. Gruenheid, and B.B. Finlay Microbial pathogenesis and cytoskeletal function Nature 422 2003 775 781
3. P. Cossart, and P.J. Sansonetti Bacterial invasion: the paradigms of enteroinvasive pathogens Science 304 2004 242 248
4. H. Wu, and J.T. Parsons Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex J. Cell Biol. 120 1993 1417 1426
5. N. Martinez-Quiles Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP Mol. Cell. Biol. 24 2004 5269 5280
6. L. Bougneres Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells J. Cell Biol. 166 2004 225 235
7. S.A. Weed, and J.T. Parsons Cortactin: coupling membrane dynamics to cortical actin assembly Oncogene 20 2001 6418 6434
8. R.J. Daly Cortactin signaling and dynamic actin networks Biochem. J. 382 2004 13 25
9. T. Uruno Activation of Arp2/3 complex-mediated actin polymerization by cortactin Nat. Cell Biol. 3 2001 259 266
10. A.M. Weaver Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation Curr. Biol. 11 2001 370 374
11. S.A. Weed Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex J. Cell Biol. 151 2000 29 40
12. S.A. Weed Translocation of cortactin to the cell periphery is mediated by the small GTPase Rac1 J. Cell Sci. 111 1998 2433 2443
13. C. Vidal Cdc42/Rac1-dependent activation of the p21-activated kinase (Pak) regulates human platelet lamellipodia spreading: implication of the cortical-actin binding protein cortactin Blood 100 2002 4462 4469
14. C. Huang The role of tyrosine phosphorylation of cortactin in the locomotion of endothelial cells J. Biol. Chem. 273 1998 25770 25776
15. L. Crostella Hepatocyte Growth Factor/scatter factor-induces phosphorylation of cortactin in A431 cells in a Src kinase-independent manner Oncogene 20 2001 3735 3745
16. L. Fan Actin depolymerization-induced tyrosine phosphorylation of cortactin: the role of Fer kinase Biochem. J. 380 2004 581 591
17. D.H. Campbell Signaling pathways and structural domains required for phosphorylation of EMS1/cortactin Cancer Res. 59 1999 5376 5385
18. K. Mizutani Essential role of neural Wiskott-Aldrich syndrome protein in podosome formation and degradation of extracellular matrix in src-transformed fibroblasts Cancer Res. 62 2002 669 674
19. K.G. Campellone, and J.M. Leong Tails of two Tirs: actin pedestal formation by enteropathogenic E. coli and enterohemorrhagic E. coli O157:H7 Curr. Opin. Microbiol. 6 2003 82 90
20. N. Phillips Phosphorylation of the enteropathogenic E. coli receptor by the Src-family kinase c-Fyn triggers actin pedestal formation Nat. Cell Biol. 6 2004 618 625
21. A. Swimm Enteropathogenic Escherichia coli use redundant tyrosine kinases to form actin pedestals Mol. Biol. Cell. 15 2004 3520 3529
22. V.V. Cantarelli Interaction of enteropathogenic or enterohemorrhagic Escherichia coli with HeLa cells results in translocation of cortactin to the bacterial adherence site Infect. Immun. 68 2000 382 386
23. J. Celli Enteropathogenic Escherichia coli (EPEC) attachment to epithelial cells: exploiting the host cell cytoskeleton from the outside Cell. Microbiol. 2 2000 1 9
24. S. Lommel Enterohaemorrhagic and enteropathogenic Escherichia coli use different mechanisms for actin pedestal formation that converge on N-WASP Cell. Microbiol. 6 2004 243 254
25. S. Gruenheid Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells Nat. Cell Biol. 3 2001 856 859
26. V.V. Cantarelli Cortactin is necessary for F-actin accumulation in pedestal structures induced by enteropathogenic Escherichia coli infection Infect. Immun. 70 2002 2206 2209
27. D.L. Goosney Recruitment of cytoskeletal and signaling proteins to enteropathogenic and enterohemorrhagic Escherichia coli pedestals Infect. Immun. 69 2001 3315 3322
28. K.G. Campellone EspFU is a translocated EHEC effector that interacts with Tir and N-WASP and promotes Nck-independent actin assembly Dev. Cell. 7 2004 217 228
29. M.J. Blaser, and J.C. Atherton Helicobacter pylori persistence: biology and disease J. Clin. Invest. 113 2004 321 333
30. M. Stein c-Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs Mol. Microbiol. 43 2002 971 980
31. M. Selbach Src is the kinase of the Helicobacter pylori CagA protein in vitro and in vivo J. Biol. Chem. 277 2002 6775 6778
32. H. Higashi SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein Science 295 2002 683 686
33. R. Tsutsumi Attenuation of Helicobacter pylori CagA x SHP-2 signaling by interaction between CagA and C-terminal Src kinase J. Biol. Chem. 278 2003 3664 3670
34. M. Selbach The Helicobacter pylori CagA protein induces cortactin dephosphorylation and actin rearrangement by c-Src inactivation EMBO J. 22 2003 515 528
35. M. Selbach The Helicobacter pylori CagA protein induces tyrosine dephosphorylation of ezrin Proteomics 4 2004 2961 2968
36. S. Backert Functional analysis of the cag pathogenicity island in Helicobacter pylori isolates from patients with gastritis, peptic ulcer and gastric cancer Infect. Immun. 72 2004 1043 1056
37. - Helicobacter pylori J. Immunol. 163 1999 5552 5559
38. H. Mimuro Grb2 is a key mediator of Helicobacter pylori CagA protein activities Mol. Cell. 10 2002 745 755
39. M.R. Amieva Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA Science 300 2003 1430 1434
40. F. Frischknecht, and M. Way Surfing pathogens and the lessons learned for actin polymerization Trends Cell Biol. 11 2001 30 38
41. M.D. Welch Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes Nature 385 1997 265 269
42. T. Suzuki Neural Wiskott-Aldrich syndrome protein is implicated in the actin-based motility of Shigella flexneri EMBO J. 17 1998 2767 2776
43. M. Hollinshead Vaccinia virus utilizes microtubules for movement to the cell surface J. Cell Biol. 154 2001 389 402
44. J. Rietdorf Kinesin-dependent movement on microtubules precedes actin-based motility of vaccinia virus Nat. Cell Biol. 3 2001 992 1000
45. N. Scaplehorn Grb2 and Nck act cooperatively to promote actin-based motility of vaccinia virus Curr. Biol. 12 2002 740 745
46. T.P. Loisel Reconstitution of actin-based motility of Listeria and Shigella using pure proteins Nature 401 1999 613 616
47. M. Zettl, and M. Way New tricks for an old dog? Nat. Cell Biol. 3 2001 E74 E75
48. T. Uruno Sequential interaction of actin-related proteins 2 and 3 (Arp2/3) complex with neural Wiscott-Aldrich syndrome protein (N-WASP) and cortactin during branched actin filament network formation J. Biol. Chem. 278 2003 26086 26093
49. F. Frischknecht Tyrosine phosphorylation is required for actin-based motility of vaccinia but not Listeria or Shigella Curr. Biol. 9 1999 89 92
50. T.P. Newsome Src mediates a switch from microtubule- to actin-based motility of vaccinia virus Science 306 2004 124 129
51. E. Gouin The RickA protein of Rickettsia conorii activates the Arp2/3 complex Nature 427 2004 457 461
52. G. Tran Van Nhieu Bacterial signals and cell responses during Shigella entry into epithelial cells Cell. Microbiol. 2 2000 187 193
53. T. Suzuki, and C. Sasakawa Molecular basis of the intracellular spreading of Shigella Infect. Immun. 69 2001 5959 5966
54. C. Dehio Invasion of epithelial cells by Shigella flexneri induces tyrosine phosphorylation of cortactin by a pp60c-src-mediated signaling pathway EMBO J. 14 1995 2471 2482
55. A.E. Engqvist-Goldstein, and D.G. Drubin Actin assembly and endocytosis: from yeast to mammals Annu. Rev. Cell Dev. Biol. 19 2003 287 332
56. D.A. Schafer Regulating actin dynamics at membranes: a focus on dynamin Traffic 5 2004 463 469
57. M.A. McNiven Regulated interactions between dynamin and the actin-binding protein cortactin modulate cell shape J. Cell Biol. 151 2000 187 198
58. H. Cao Cortactin is a component of clathrin-coated pits and participates in receptor-mediated endocytosis Mol. Cell. Biol. 23 2003 2162 2170
59. X.M. Chen Cryptosporidium parvum invasion of biliary epithelia requires host cell tyrosine phosphorylation of cortactin via c-Src Gastroenterology 125 2003 216 228
60. F.S. Fawaz Infection with Chlamydia trachomatis alters the tyrosine phosphorylation and/or localization of several host cell proteins including cortactin Infect. Immun. 65 1997 5301 5308
61. D.R. Clifton A chlamydial type III translocated protein is tyrosine-phosphorylated at the site of entry and associated with recruitment of actin Proc. Natl. Acad. Sci. U. S. A. 101 2004 10166 10171
62. R.C. Robinson Crystal structure of Arp2/3 complex Science 294 2001 1679 1684
63. A.M. Weaver Integration of signals to the Arp2/3 complex Curr. Opin. Cell Biol. 15 2003 23 30
64. T.H. Millard Signaling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex Biochem. J. 380 2004 1 17
65. V.T. Lee, and O. Schneewind Protein secretion and the pathogenesis of bacterial infections Genes Dev. 15 2001 1725 1752
66. C. Robinson, and A. Bolhuis Protein targeting by the twin-arginine translocation pathway Nat. Rev. Mol. Cell Biol. 2 2001 350 356
67. E. Cascales, and P.J. Christie The versatile bacterial type IV secretion systems Nat. Rev. Microbiol. 1 2003 137 149
68. S. Cottet Microaerophilic conditions permit to mimic in vitro events occurring during in vivo Helicobacter pylori infection and to identify Rho/Ras-associated proteins in cellular signaling J. Biol. Chem. 277 2002 33978 33986
69. I. Hoffmann Activation of ErbB2 receptor tyrosine kinase supports invasion of endothelial cells by Neisseria meningitidis J. Cell Biol. 155 2001 133 143
70. J.J. Martinez, and P. Cossart Early signaling events involved in the entry of Rickettsia conorii into mammalian cells J. Cell Sci. 117 2004 5097 5106