Src mediates a switch from microtubule- to actin-based motility of vaccinia virus

Science

Volumn 306, Issue 5693, 2004, Pages 124-129

  Newsome, Timothy P ^a   Scaplehorn, Niki ^a   Way, Michael ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; POLYMERIZATION; REACTION KINETICS; VIRUSES;

ACTIN; MOTILITY; PLASMA MEMBRANES; VIRAL MEMBRANE PROTEINS;

PROTEINS;

ACTIN; KINESIN; PROTEIN TYROSINE KINASE; TYROSINE; VIRUS PROTEIN; 42KDA PROTEIN, VACCINIA VIRUS; A36R PROTEIN, VACCINIA VIRUS; HYBRID PROTEIN; MEMBRANE PROTEIN; PHOSPHOTYROSINE; VIRUS ENVELOPE PROTEIN;

MEDICINE;

ARTICLE; CELL MEMBRANE; CELL MOTILITY; CONTROLLED STUDY; MICROTUBULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; VACCINIA VIRUS; VIRUS ENVELOPE; ANIMAL; CELL LINE; CHEMISTRY; CHICKEN; CONSENSUS SEQUENCE; ENZYME ACTIVATION; GENETICS; HELA CELL; HUMAN; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; VIRION; VIROLOGY;

DNA VIRUSES; VACCINIA VIRUS;

ACTINS; ANIMALS; CELL LINE; CELL MEMBRANE; CHICKENS; CONSENSUS SEQUENCE; ENZYME ACTIVATION; HELA CELLS; HUMANS; KINESIN; MEMBRANE GLYCOPROTEINS; MICROTUBULES; PHOSPHORYLATION; PHOSPHOTYROSINE; RECOMBINANT FUSION PROTEINS; SRC-FAMILY KINASES; VACCINIA VIRUS; VIRAL ENVELOPE PROTEINS; VIRAL STRUCTURAL PROTEINS; VIRION;

EID: 6044223321     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1101509     Document Type: Article

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27. We thank G. Superti-Furga and J. Krijnse-Locker for providing monoclonal antibody (mAb) 3-27, Src-GFP, and mAb 19C2; G. Smith for the ΔB5R virus; and the Way lab, N. Hogg, C. Schiavo, and K. Dorey for helpful comments. Supported by the Human Frontier Science Program (T.P.N.). Molecular interaction data have been deposited in the Biomolecular Interaction Network Database with accession codes 151863 and 151864.