-
1
-
-
0027523517
-
A first step in the development of gene therapy for colorectal carcinoma: Cloning, sequencing, and expression of Escherichia coli cytosine deaminase
-
Austin E.A., Huber B.E. A first step in the development of gene therapy for colorectal carcinoma Cloning, sequencing, and expression of Escherichia coli cytosine deaminase . Mol. Pharmacol. 43:1993;380-387.
-
(1993)
Mol. Pharmacol.
, vol.43
, pp. 380-387
-
-
Austin, E.A.1
Huber, B.E.2
-
2
-
-
0027787053
-
In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gener therapy
-
Bi, W. L.; Parysek, L. M.; Warnick, R.; Stambrook, P. J. In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gener therapy. Hum. Gene Ther. 4:725-531; 1993.
-
(1993)
Hum. Gene Ther.
, vol.4
, pp. 725-531
-
-
Bi, W.L.1
Parysek, L.M.2
Warnick, R.3
Stambrook, P.J.4
-
3
-
-
0026772206
-
In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors
-
Culver K.W., Ram Z., Wallbridge S., Ishii H., Oldfield E.H., Blaese R.M. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science. 256:1992;1550-1552.
-
(1992)
Science
, vol.256
, pp. 1550-1552
-
-
Culver, K.W.1
Ram, Z.2
Wallbridge, S.3
Ishii, H.4
Oldfield, E.H.5
Blaese, R.M.6
-
4
-
-
0021726790
-
Genes with promoters in retrovirus vectors can be independently suppressed by an epigenetic mechanism
-
Emerman M., Temin H.M. Genes with promoters in retrovirus vectors can be independently suppressed by an epigenetic mechanism. Cell. 39:1984;459-467.
-
(1984)
Cell
, vol.39
, pp. 459-467
-
-
Emerman, M.1
Temin, H.M.2
-
5
-
-
0027483695
-
The "bystander effect": Tumor regression when a fraction of the tumor mass is genetically modified
-
Freeman S.M., Abboud C.N., Whartenby K.A., Packman C.H., Koeplin D.S., Moolten F.L., Abraham G.N. The "bystander effect" Tumor regression when a fraction of the tumor mass is genetically modified . Cancer Res. 53:1993;5274-5283.
-
(1993)
Cancer Res
, vol.53
, pp. 5274-5283
-
-
Freeman, S.M.1
Abboud, C.N.2
Whartenby, K.A.3
Packman, C.H.4
Koeplin, D.S.5
Moolten, F.L.6
Abraham, G.N.7
-
6
-
-
0030768615
-
Virally directed cytosine deaminase/5-fluorocytosine gene therapy enhances radiation response in human cancer xenografts
-
Hanna N.N., Mauceri H.J., Wayne J.D., Hallahan D.E., Kufe D.W., Weichselbaum R.R. Virally directed cytosine deaminase/5-fluorocytosine gene therapy enhances radiation response in human cancer xenografts. Cancer Res. 57:1997;4205-4209.
-
(1997)
Cancer Res
, vol.57
, pp. 4205-4209
-
-
Hanna, N.N.1
Mauceri, H.J.2
Wayne, J.D.3
Hallahan, D.E.4
Kufe, D.W.5
Weichselbaum, R.R.6
-
7
-
-
0028795075
-
In vivo adenovirus-mediated gene transfer of the Escherichia coli cytosine deaminase gene to human colon carcinoma-derived tumors induces chemosensitivity to 5-fluorocytosine
-
Hirchowitz E.A., Ohwada A., Pascal W.R., Russi T.J., Crystal R.G. In vivo adenovirus-mediated gene transfer of the Escherichia coli cytosine deaminase gene to human colon carcinoma-derived tumors induces chemosensitivity to 5-fluorocytosine. Hum. Gene Ther. 6:1995;1055-1063.
-
(1995)
Hum. Gene Ther.
, vol.6
, pp. 1055-1063
-
-
Hirchowitz, E.A.1
Ohwada, A.2
Pascal, W.R.3
Russi, T.J.4
Crystal, R.G.5
-
8
-
-
0027496518
-
In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase
-
Huber B.E., Austin E.A., Good S.S., Knick V.C., Tibbels S., Richards C.A. In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase. Cancer Res. 53:1993;4619-4626.
-
(1993)
Cancer Res
, vol.53
, pp. 4619-4626
-
-
Huber, B.E.1
Austin, E.A.2
Good, S.S.3
Knick, V.C.4
Tibbels, S.5
Richards, C.A.6
-
9
-
-
0028108469
-
Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: Significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase
-
Huber B.E., Austin E.A., Richards C.A., Davis S.T., Good S.S. Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene Significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase . Proc. Natl. Acad. Sci. USA. 91:1994;8302-8306.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8302-8306
-
-
Huber, B.E.1
Austin, E.A.2
Richards, C.A.3
Davis, S.T.4
Good, S.S.5
-
10
-
-
0031043426
-
In vivo gene therapy for a-fetoprotein-cytosine deaminase gene
-
Kanai F., Lan K.H., Shiratori Y., Tanako T., Ohashi M., Okudaira T., Yashida Y., Wakimoto H., Hamado H., Nakabayashi H., Tamaoki T., Omata M. In vivo gene therapy for a-fetoprotein-cytosine deaminase gene. Cancer Res. 57:1997;461-465.
-
(1997)
Cancer Res
, vol.57
, pp. 461-465
-
-
Kanai, F.1
Lan, K.H.2
Shiratori, Y.3
Tanako, T.4
Ohashi, M.5
Okudaira, T.6
Yashida, Y.7
Wakimoto, H.8
Hamado, H.9
Nakabayashi, H.10
Tamaoki, T.11
Omata, M.12
-
11
-
-
0030052050
-
Radiosensitization by 5-fluorocytosine of human colorectal carcinoma cells in culture transduced with cytosine deaminase gene
-
Khil M.S., Kim J.H., Mullen C.A., Kim S.H., Freytag S.O. Radiosensitization by 5-fluorocytosine of human colorectal carcinoma cells in culture transduced with cytosine deaminase gene. Clin. Cancer Res. 2:1996;53-57.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 53-57
-
-
Khil, M.S.1
Kim, J.H.2
Mullen, C.A.3
Kim, S.H.4
Freytag, S.O.5
-
12
-
-
0028032719
-
Selective enhancement by an antiviral agent of the radiation induced cell killing of human glioma cells transduced with HSV-tk gene
-
Kim J.H., Kim S.H., Brown S.L., Freytag S.O. Selective enhancement by an antiviral agent of the radiation induced cell killing of human glioma cells transduced with HSV-tk gene. Cancer Res. 54:1994;6053-6056.
-
(1994)
Cancer Res
, vol.54
, pp. 6053-6056
-
-
Kim, J.H.1
Kim, S.H.2
Brown, S.L.3
Freytag, S.O.4
-
13
-
-
0028297316
-
Tumors expressing the cytosine deaminase suicide gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild type tumor
-
Mullen C.A., Coale M.M., Lowe R., Blaese R.M. Tumors expressing the cytosine deaminase suicide gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild type tumor. Cancer Res. 54:1994;1503-1506.
-
(1994)
Cancer Res
, vol.54
, pp. 1503-1506
-
-
Mullen, C.A.1
Coale, M.M.2
Lowe, R.3
Blaese, R.M.4
-
14
-
-
0026599586
-
Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: A negative selection system. Proc
-
Mullen C.A., Kilstrup M., Blaese R.M. Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine A negative selection system. Proc . Natl. Acad. Sci. USA. 89:1992;33-37.
-
(1992)
Natl. Acad. Sci. USA
, vol.89
, pp. 33-37
-
-
Mullen, C.A.1
Kilstrup, M.2
Blaese, R.M.3
-
15
-
-
0029743164
-
Regional delivery of an adenovirus vector containing the Escheria coli cytosine deaminase gene to provide local activation of 5-fluorocytosine to suppress the growth of colon carcinoma metastatic to liver
-
Ohwada A., Hirschowitz E.A., Crystal R.G. Regional delivery of an adenovirus vector containing the Escheria coli cytosine deaminase gene to provide local activation of 5-fluorocytosine to suppress the growth of colon carcinoma metastatic to liver. Hum. Gene Ther. 7:1996;1567-1576.
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 1567-1576
-
-
Ohwada, A.1
Hirschowitz, E.A.2
Crystal, R.G.3
-
16
-
-
0031025998
-
Gene therapy for cancer: What have we done and where are we going?
-
Roth A.J., Cristiano R.J. Gene therapy for cancer What have we done and where are we going? J. Natl. Cancer Inst. 89:1997;21-39.
-
(1997)
J. Natl. Cancer Inst.
, vol.89
, pp. 21-39
-
-
Roth, A.J.1
Cristiano, R.J.2
-
17
-
-
0025651424
-
Fluorodeoxyuridine-induced radiosensitization and inhibition of DNA double strand break repair in human colon cancer cells
-
Bruso C.E., Shewach D.S., Lawrence T.S. Fluorodeoxyuridine-induced radiosensitization and inhibition of DNA double strand break repair in human colon cancer cells. Int. J. Radiat. Oncol. Biol. Phys. 19:1990;1411-1417.
-
(1990)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.19
, pp. 1411-1417
-
-
Bruso, C.E.1
Shewach, D.S.2
Lawrence, T.S.3
-
18
-
-
0022511464
-
Combined use of drugs and radiation in the treatment of liver metastases
-
Byfield J.E. Combined use of drugs and radiation in the treatment of liver metastases. Cancer Res. 100:1986;298-304.
-
(1986)
Cancer Res
, vol.100
, pp. 298-304
-
-
Byfield, J.E.1
-
19
-
-
0020393438
-
Pharmacologic requirements for obtaining sensitization of human tumor cells in vitro to combined 5-fluorouracil or ftorafur and x rays
-
Byfield J.E., Calabro-Jones P., Klisak I., Kulhanian F. Pharmacologic requirements for obtaining sensitization of human tumor cells in vitro to combined 5-fluorouracil or ftorafur and x rays. Int. J. Radiat. Oncol. Biol. Phys. 8:1982;1923-1933.
-
(1982)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.8
, pp. 1923-1933
-
-
Byfield, J.E.1
Calabro-Jones, P.2
Klisak, I.3
Kulhanian, F.4
-
20
-
-
0025611018
-
Metabolism and mechanism of action of 5-fluorouracil
-
Parker W.B., Cheng Y.C. Metabolism and mechanism of action of 5-fluorouracil. Pharmacol. Ther. 48:1990;381-395.
-
(1990)
Pharmacol. Ther.
, vol.48
, pp. 381-395
-
-
Parker, W.B.1
Cheng, Y.C.2
-
21
-
-
0026028777
-
5-Fluorouracil modulation of radiosensitivity in cultured human carcinoma cells
-
Smalley S.R., Kimler B.F., Evans R.G. 5-Fluorouracil modulation of radiosensitivity in cultured human carcinoma cells. Int. J. Radiat. Oncol. Biol. Phys. 20:1991;207-211.
-
(1991)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.20
, pp. 207-211
-
-
Smalley, S.R.1
Kimler, B.F.2
Evans, R.G.3
-
22
-
-
0022970363
-
Experimental studies on interactions of radiation and cancer chemotherapeutic drugs in normal tissues and a solid tumour
-
von der Maase H. Experimental studies on interactions of radiation and cancer chemotherapeutic drugs in normal tissues and a solid tumour. Radiother. Oncol. 7:1986;47-68.
-
(1986)
Radiother. Oncol.
, vol.7
, pp. 47-68
-
-
Von Der Maase, H.1
-
23
-
-
0025991626
-
Biochemical parmacology and analysis of fluoropyrimidines alone and in combination with modulators
-
Weckbecker G. Biochemical parmacology and analysis of fluoropyrimidines alone and in combination with modulators. Pharmac. Ther. 50:1991;367-424.
-
(1991)
Pharmac. Ther.
, vol.50
, pp. 367-424
-
-
Weckbecker, G.1
-
24
-
-
0017239402
-
14C in mouse, rat, rabbit, dog and man
-
14C in mouse, rat, rabbit, dog and man. Chemotherapy. 22:1976;137-153.
-
(1976)
Chemotherapy
, vol.22
, pp. 137-153
-
-
Polak, A.1
Eschenhof, E.2
Fernex, M.3
Scholer, H.J.4
|