메뉴 건너뛰기




Volumn 534, Issue , 2003, Pages 69-96

Pancreatic islet and stem cell transplantation in diabetes mellitus: Results and perspectives

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT;

EID: 1542752546     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-0063-6_6     Document Type: Review
Times cited : (4)

References (118)
  • 1
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group, 1993, The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N. Engl. J. Med. 329, 977-986.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 977-986
  • 2
    • 0027286787 scopus 로고
    • Meta-analysis of effects of intensive blood-glucose control on late complications of type-1 diabetes
    • Wang, P.H., Lau, J., and Chalmers, T.C., 1993, Meta-analysis of effects of intensive blood-glucose control on late complications of type-1 diabetes. Lancet 341, 1306-1309.
    • (1993) Lancet , vol.341 , pp. 1306-1309
    • Wang, P.H.1    Lau, J.2    Chalmers, T.C.3
  • 3
    • 0031006603 scopus 로고    scopus 로고
    • Hypoglycemia in the Diabetes Control and Complications Trial
    • The Diabetes Control and Complications Trial Research Group, 1997, Hypoglycemia in the Diabetes Control and Complications Trial. Diabetes 46, 271-286
    • (1997) Diabetes , vol.46 , pp. 271-286
  • 7
    • 0033016901 scopus 로고    scopus 로고
    • Risks and benefits of kidney and pancreas transplantation for diabetic patients
    • Manske, C.L., 1999, Risks and benefits of kidney and pancreas transplantation for diabetic patients. Diabetes Care 22, B114-B120.
    • (1999) Diabetes Care , vol.22
    • Manske, C.L.1
  • 8
    • 0033960992 scopus 로고    scopus 로고
    • Decreased surgical risks of pancreas transplantation in the modern era
    • Humar, A., Kandaswamy, R., Granger, D. et al., 2000, Decreased surgical risks of pancreas transplantation in the modern era. Ann. Surg. 231, 342-344.
    • (2000) Ann. Surg. , vol.231 , pp. 342-344
    • Humar, A.1    Kandaswamy, R.2    Granger, D.3
  • 9
    • 0032797249 scopus 로고    scopus 로고
    • Percutaneous transhepatic catheterization of the portal vein: A combined CT- and fluoroscopy-guided technique
    • Weimar, B., Rauber, K., Brendel, M.D., Bretzel, R.G., and Rau, W.S., 1999, Percutaneous transhepatic catheterization of the portal vein: a combined CT- and fluoroscopy-guided technique. Cardiovasc. Intervent. Radiol. 22, 342-344.
    • (1999) Cardiovasc. Intervent. Radiol. , vol.22 , pp. 342-344
    • Weimar, B.1    Rauber, K.2    Brendel, M.D.3    Bretzel, R.G.4    Rau, W.S.5
  • 10
  • 11
    • 0026293707 scopus 로고
    • Fresh human islet transplantation to replace pancreatic endocrine function in type 1 diabetic patients. Report of six cases
    • Socci, C., Falqui, L., Davalli, A.M., Ricordi, C., Braghi, S., Bertuzzi, F. et al., 1991, Fresh human islet transplantation to replace pancreatic endocrine function in type 1 diabetic patients. Report of six cases. Acta Diabetol. 28, 151-157.
    • (1991) Acta Diabetol. , vol.28 , pp. 151-157
    • Socci, C.1    Falqui, L.2    Davalli, A.M.3    Ricordi, C.4    Braghi, S.5    Bertuzzi, F.6
  • 12
    • 0026526838 scopus 로고
    • Long-term follow-up after transplantation of insulin-producing pancreatic islets into patients with Type 1 (insulin-dependent) diabetes mellitus
    • Warnock, G.L., Kneteman, N.M., Ryan, E.A., Rabinovitch, A., and Rajotte, R.V., 1992, Long-term follow-up after transplantation of insulin-producing pancreatic islets into patients with Type 1 (insulin-dependent) diabetes mellitus. Diabetologia 35, 89-95.
    • (1992) Diabetologia , vol.35 , pp. 89-95
    • Warnock, G.L.1    Kneteman, N.M.2    Ryan, E.A.3    Rabinovitch, A.4    Rajotte, R.V.5
  • 13
    • 0027529902 scopus 로고
    • Insulin independence in type I diabetes after transplantation of unpurified islets from single donor with 15-deoxyspergualin
    • Gores, P.F., Najarian, J.S., Stephanian, E., Lloveras, J.J., Kelley, S.L., and Sutherland, D.E.R., 1993, Insulin independence in type I diabetes after transplantation of unpurified islets from single donor with 15-deoxyspergualin. Lancet 341, 19-21.
    • (1993) Lancet , vol.341 , pp. 19-21
    • Gores, P.F.1    Najarian, J.S.2    Stephanian, E.3    Lloveras, J.J.4    Kelley, S.L.5    Sutherland, D.E.R.6
  • 16
    • 0002920550 scopus 로고    scopus 로고
    • Biological alternatives to insulin therapy
    • Bretzel, R.G., 1999, Biological alternatives to insulin therapy. Exp. Clin. Endocrinol. Diabetes 107, S39-S43.
    • (1999) Exp. Clin. Endocrinol. Diabetes , vol.107
    • Bretzel, R.G.1
  • 18
    • 0001865624 scopus 로고
    • Weitere mittheilungen über den diabetes mellitus nach exstirpation des pankreas
    • Minkowski, O., 1892, Weitere Mittheilungen über den Diabetes mellitus nach Exstirpation des Pankreas. Berliner Klin. Wochenschr. 29, 90-94.
    • (1892) Berliner Klin. Wochenschr. , vol.29 , pp. 90-94
    • Minkowski, O.1
  • 19
    • 50749118593 scopus 로고
    • The internal secretion of the pancreas
    • Banting, F.G., and Best, C.H., 1922, The internal secretion of the pancreas. J. Lab. Clin. Invest. 7, 251-266.
    • (1922) J. Lab. Clin. Invest. , vol.7 , pp. 251-266
    • Banting, F.G.1    Best, C.H.2
  • 20
    • 0001529118 scopus 로고
    • Notes on diabetes treated with extract and by grafts of sheep's pancreas
    • Williams, P.W., 1894, Notes on diabetes treated with extract and by grafts of sheep's pancreas. Brit. Med. J. 2, 1303.
    • (1894) Brit. Med. J. , vol.2 , pp. 1303
    • Williams, P.W.1
  • 21
    • 0023912253 scopus 로고
    • Automated method for isolation of human pancreatic islets
    • Ricordi, C., Lacy, P.E., Finke, E.H., Olack, B.J., and Scharp, D.W., 1988, Automated method for isolation of human pancreatic islets. Diabetes 37, 413-420.
    • (1988) Diabetes , vol.37 , pp. 413-420
    • Ricordi, C.1    Lacy, P.E.2    Finke, E.H.3    Olack, B.J.4    Scharp, D.W.5
  • 23
  • 24
    • 0030754411 scopus 로고    scopus 로고
    • Proinsulin C-peptide - Biological activity?
    • Steiner, D.F., and Rubenstein, A.H., 1997, Proinsulin C-peptide - biological activity? [comment]. Science 277, 531-532.
    • (1997) Science , vol.277 , pp. 531-532
    • Steiner, D.F.1    Rubenstein, A.H.2
  • 26
    • 0032558096 scopus 로고    scopus 로고
    • Improved glucose counterregulation and autonomic symptoms after intraportal islet transplants alone in patients with type I diabetes mellitus
    • Meyer, C., Hering, B.J., Grossmann, R., Brandhorst, H., Brandhorst, D., Gerich, J., Federlin, K., 61nd Bretzel, R.G., 1998, Improved glucose counterregulation and autonomic symptoms after intraportal islet transplants alone in patients with type I diabetes mellitus. Transplantation 66, 233-240.
    • (1998) Transplantation , vol.66 , pp. 233-240
    • Meyer, C.1    Hering, B.J.2    Grossmann, R.3    Brandhorst, H.4    Brandhorst, D.5    Gerich, J.6    Federlin, K.7    Bretzel, R.G.8
  • 31
    • 0025279590 scopus 로고
    • Differential roles of Mac-1+ cells and CD4+ and CD8+ T lymphocytes in primary nonfunction and classical rejection of islet allografts
    • Kaufman, D.B., Platt, J.L., Rabe, F.L., Dunn, D.L., Bach, F.H., and Sutherland, D.E.R., 1990, Differential roles of Mac-1+ cells and CD4+ and CD8+ T lymphocytes in primary nonfunction and classical rejection of islet allografts. J. Exp. Med. 172, 291-302.
    • (1990) J. Exp. Med. , vol.172 , pp. 291-302
    • Kaufman, D.B.1    Platt, J.L.2    Rabe, F.L.3    Dunn, D.L.4    Bach, F.H.5    Sutherland, D.E.R.6
  • 32
    • 0031890972 scopus 로고    scopus 로고
    • Transplantation of allogeneic islets of Langerhans in the rat liver. Effects of macrophage depletion on graft survival and microenvironment activation
    • Bottino, R., Fernandez, L.A., Ricordi, C., Lehmann, R., Tsan, M.F., Oliver, R., and Inverardi, L., 1998, Transplantation of allogeneic islets of Langerhans in the rat liver. Effects of macrophage depletion on graft survival and microenvironment activation. Diabetes 47, 316-323.
    • (1998) Diabetes , vol.47 , pp. 316-323
    • Bottino, R.1    Fernandez, L.A.2    Ricordi, C.3    Lehmann, R.4    Tsan, M.F.5    Oliver, R.6    Inverardi, L.7
  • 33
    • 0026446002 scopus 로고
    • Influence of experimental hyperglycemia on microvascular blood perfusion of pancreatic islet isografts
    • Menger, M.D., Vajkoczy, P., Leiderer, R., Jager, S., and Messmer, K., 1992, Influence of experimental hyperglycemia on microvascular blood perfusion of pancreatic islet isografts. J. Clin. Invest. 90, 1361-1369.
    • (1992) J. Clin. Invest. , vol.90 , pp. 1361-1369
    • Menger, M.D.1    Vajkoczy, P.2    Leiderer, R.3    Jager, S.4    Messmer, K.5
  • 34
    • 0035862989 scopus 로고    scopus 로고
    • Endotoxin-mediated delayed islet graft function is associated with increased intra-islet cytokine production and islet cell apoptosis
    • Berney, T., Molano, R.D., Cattan, P. et al., 2001, Endotoxin-mediated delayed islet graft function is associated with increased intra-islet cytokine production and islet cell apoptosis. Transplantation 71, 125-132.
    • (2001) Transplantation , vol.71 , pp. 125-132
    • Berney, T.1    Molano, R.D.2    Cattan, P.3
  • 35
    • 0032883638 scopus 로고    scopus 로고
    • Incompatibility between human blood and isolated islets of Langerhans: A finding with implications for clinical intraportal islet transplantation?
    • Bennet, W., Sunberg, B., Groth, C.G. et al., 1999, Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation? Diabetes 48, 1907-1914.
    • (1999) Diabetes , vol.48 , pp. 1907-1914
    • Bennet, W.1    Sunberg, B.2    Groth, C.G.3
  • 39
    • 0029819877 scopus 로고    scopus 로고
    • Islet cell antibodies and GAD65 antibodies in IDDM patients undergoing kidney and islet after kidney transplantation
    • Jaeger, C., Hering, B.J., Dyrberg, T., Federlin, K., and Bretzel, R.G., 1996, Islet cell antibodies and GAD65 antibodies in IDDM patients undergoing kidney and islet after kidney transplantation. Transplantation 62, 424-426.
    • (1996) Transplantation , vol.62 , pp. 424-426
    • Jaeger, C.1    Hering, B.J.2    Dyrberg, T.3    Federlin, K.4    Bretzel, R.G.5
  • 40
    • 0030695038 scopus 로고    scopus 로고
    • Progressive islet graft failure occurs significantly earlier in autoantibody positive than in autoantibody negative IDDM recipients of intrahepatic islet allografts
    • Jaeger, C., Brendel, M.D., Hering, B.J., Eckhard, M., and Bretzel, R.G., 1997, Progressive islet graft failure occurs significantly earlier in autoantibody positive than in autoantibody negative IDDM recipients of intrahepatic islet allografts. Diabetes 46, 1907-1910.
    • (1997) Diabetes , vol.46 , pp. 1907-1910
    • Jaeger, C.1    Brendel, M.D.2    Hering, B.J.3    Eckhard, M.4    Bretzel, R.G.5
  • 41
    • 0033626339 scopus 로고    scopus 로고
    • Islet autoantibodies as potential markers for disease recurrence in clinical islet transplantation
    • Jaeger, C., Brendel, M.D., Eckhard, M., and Bretzel, R.G., 2000, Islet autoantibodies as potential markers for disease recurrence in clinical islet transplantation. Exp. Clin. Endocrinol. Diabetes 108, 328-333.
    • (2000) Exp. Clin. Endocrinol. Diabetes , vol.108 , pp. 328-333
    • Jaeger, C.1    Brendel, M.D.2    Eckhard, M.3    Bretzel, R.G.4
  • 42
    • 0033958643 scopus 로고    scopus 로고
    • Modulation of humoral islet autoimmunity by pancreas allotransplantation influences allograft outcome in patients with type 1 diabetes
    • Braghi, S., Bonifacio, E., Secchi, A., di Carlo, V., Pozza, G., and Bosi, E., 2000, Modulation of humoral islet autoimmunity by pancreas allotransplantation influences allograft outcome in patients with type 1 diabetes. Diabetes 49, 218-224.
    • (2000) Diabetes , vol.49 , pp. 218-224
    • Braghi, S.1    Bonifacio, E.2    Secchi, A.3    Di Carlo, V.4    Pozza, G.5    Bosi, E.6
  • 43
    • 0029810878 scopus 로고    scopus 로고
    • Recurrence of autoimmune diabetes in recipients of cadaveric pancreatic grafts
    • Tyden, G., Reinholt, F.P., Sundkvist, G., and Bolinder, J., 1996, Recurrence of autoimmune diabetes in recipients of cadaveric pancreatic grafts. N. Engl. J. Med. 335, 860-863.
    • (1996) N. Engl. J. Med. , vol.335 , pp. 860-863
    • Tyden, G.1    Reinholt, F.P.2    Sundkvist, G.3    Bolinder, J.4
  • 44
    • 0030987990 scopus 로고    scopus 로고
    • The "injury response": A concept linking nonspecific injury, acute rejection, and long-term transplant outcomes
    • Halloran, P.F., Homik, J., Goes, N., Lui, S.L., Urmson, J., Ramassar, V., and Cockfield, S.M., 1997, The "injury response": a concept linking nonspecific injury, acute rejection, and long-term transplant outcomes. Transplant. Proc. 29, 79-81.
    • (1997) Transplant. Proc. , vol.29 , pp. 79-81
    • Halloran, P.F.1    Homik, J.2    Goes, N.3    Lui, S.L.4    Urmson, J.5    Ramassar, V.6    Cockfield, S.M.7
  • 46
    • 0034721255 scopus 로고    scopus 로고
    • Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
    • Shapiro, A.M., Lakey, J.R., Ryan, E.A., Korbutt, G.S., Toth, E., Warnock, G.L., Kneteman, N.M., and Rajotte, R.V., 2000, Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N. Engl. J. Med. 343, 230-238.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 230-238
    • Shapiro, A.M.1    Lakey, J.R.2    Ryan, E.A.3    Korbutt, G.S.4    Toth, E.5    Warnock, G.L.6    Kneteman, N.M.7    Rajotte, R.V.8
  • 47
    • 0035085643 scopus 로고    scopus 로고
    • Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol
    • Ryan, E.A., Lakey, J.R.T., Rajotte, R.V. et al., 2001, Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. Diabetes 50, 710-719.
    • (2001) Diabetes , vol.50 , pp. 710-719
    • Ryan, E.A.1    Lakey, J.R.T.2    Rajotte, R.V.3
  • 48
    • 0001998519 scopus 로고    scopus 로고
    • Results, research priorities, and reasons for optimism: Islet transplantation for patients with type 1 diabetes
    • Hering, B.J., and Ricordi, C., 1999, Results, research priorities, and reasons for optimism: Islet transplantation for patients with type 1 diabetes. Graft 2, 12-27.
    • (1999) Graft , vol.2 , pp. 12-27
    • Hering, B.J.1    Ricordi, C.2
  • 49
    • 0036186826 scopus 로고    scopus 로고
    • Combination therapy with low dose sirolimus and tacrolimus is synergistic in preventing spontaneous and recurrent autoimmune diabetes in non-obese diabetic mice
    • Shapiro, A.M.J., Suarez-Pinzon, W.L., Power, R., and Rabinovitch, A., 2002, Combination therapy with low dose sirolimus and tacrolimus is synergistic in preventing spontaneous and recurrent autoimmune diabetes in non-obese diabetic mice. Diabetologia 45, 224-230.
    • (2002) Diabetologia , vol.45 , pp. 224-230
    • Shapiro, A.M.J.1    Suarez-Pinzon, W.L.2    Power, R.3    Rabinovitch, A.4
  • 50
    • 0033553613 scopus 로고    scopus 로고
    • GAD, a single autoantigen for diabetes
    • Boehmer, H. von, and Sarukhan, A., 1999, GAD, a single autoantigen for diabetes, [comment]. Science 384, 1135-1137.
    • (1999) Science , vol.384 , pp. 1135-1137
    • Von Boehmer, H.1    Sarukhan, A.2
  • 52
  • 53
    • 0029975996 scopus 로고    scopus 로고
    • The metabolic impact of rapamycin (sirolimus) in chronic canine islet graft recipients
    • Kneteman, N.M., Lakey, J.R., Wagner, T., and Finegood, D., 1996, The metabolic impact of rapamycin (sirolimus) in chronic canine islet graft recipients. Transplantation 61, 1206-1210.
    • (1996) Transplantation , vol.61 , pp. 1206-1210
    • Kneteman, N.M.1    Lakey, J.R.2    Wagner, T.3    Finegood, D.4
  • 56
    • 0032696447 scopus 로고    scopus 로고
    • Transplantation tolerance: Where do we stand?
    • Waldmann, H., 1999, Transplantation tolerance: where do we stand? Nat. Med. 11, 1245-1248.
    • (1999) Nat. Med. , vol.11 , pp. 1245-1248
    • Waldmann, H.1
  • 57
    • 4143058743 scopus 로고    scopus 로고
    • The role of bone marrow transplantation in tolerance: Organ-specific and cellular grafts
    • Acholonu, I.N., and Ildstad, S.T., 1999, The role of bone marrow transplantation in tolerance: organ-specific and cellular grafts. Curr. Opin. Organ Transplant. 4, 189-196.
    • (1999) Curr. Opin. Organ Transplant. , vol.4 , pp. 189-196
    • Acholonu, I.N.1    Ildstad, S.T.2
  • 61
    • 0036218296 scopus 로고    scopus 로고
    • Transplantation tolerance: Of mice and men
    • Chong, A.S., Yin, D., and Boussy, I.A., 2002, Transplantation tolerance: of mice and men. Graft 5, 27-33.
    • (2002) Graft , vol.5 , pp. 27-33
    • Chong, A.S.1    Yin, D.2    Boussy, I.A.3
  • 62
    • 0033965079 scopus 로고    scopus 로고
    • Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand
    • Kawai, T., Andrews, D., Colvin, R.B., Sachs, D.H., and Cosimi, A.B., 2000, Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand. Nat. Med 6, 114.
    • (2000) Nat. Med. , vol.6 , pp. 114
    • Kawai, T.1    Andrews, D.2    Colvin, R.B.3    Sachs, D.H.4    Cosimi, A.B.5
  • 63
    • 0033965079 scopus 로고    scopus 로고
    • Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand
    • Kirk, A.D., and Harlan, D.M., 2000, Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand (reply). Nat. Med 6, 114.
    • (2000) Nat. Med. , vol.6 , pp. 114
    • Kirk, A.D.1    Harlan, D.M.2
  • 64
    • 0029585548 scopus 로고
    • Islet transplantation in immunoseparating membranes for treatment of insulin-dependent diabetes mellitus
    • Zekorn, T., Horcher, A., Siebers, U., Federlin, K., and Bretzel, R.G., 1995, Islet transplantation in immunoseparating membranes for treatment of insulin-dependent diabetes mellitus. Exp. Clin. Endocrinol. Diabetes 103 (suppl 2), 136-139.
    • (1995) Exp. Clin. Endocrinol. Diabetes , vol.103 , Issue.SUPPL. 2 , pp. 136-139
    • Zekorn, T.1    Horcher, A.2    Siebers, U.3    Federlin, K.4    Bretzel, R.G.5
  • 65
    • 0031593197 scopus 로고    scopus 로고
    • Alginate-based microcapsules for immunoprotected islet transplantation
    • A. Prokop, D. Hunkeler, A.D. Cherrington, eds., Annals of the New York Academy of Sciences
    • Siebers, U., Horcher, A., Bretzel, R.G., Federlin, K., and Zekorn, T., 1997, Alginate-based microcapsules for immunoprotected islet transplantation. In: Bioartificial Organs: Science, Medicine and Technology (A. Prokop, D. Hunkeler, A.D. Cherrington, eds.), Annals of the New York Academy of Sciences Vol. 831, pp. 304-312.
    • (1997) Bioartificial Organs: Science, Medicine and Technology , vol.831 , pp. 304-312
    • Siebers, U.1    Horcher, A.2    Bretzel, R.G.3    Federlin, K.4    Zekorn, T.5
  • 66
    • 0033010333 scopus 로고    scopus 로고
    • Analysis of the cellular reaction towards microencapsulated xenogeneic islets after intraperitoneal transplantation
    • Siebers, U., Horcher, A., Brandhorst, H., Brandhorst, D., Hering, B., Federlin, K., Bretzel, R.G., and Zekorn, T., 1999, Analysis of the cellular reaction towards microencapsulated xenogeneic islets after intraperitoneal transplantation. J. Mol. Med. 77, 215-218.
    • (1999) J. Mol. Med. , vol.77 , pp. 215-218
    • Siebers, U.1    Horcher, A.2    Brandhorst, H.3    Brandhorst, D.4    Hering, B.5    Federlin, K.6    Bretzel, R.G.7    Zekorn, T.8
  • 67
    • 0036192342 scopus 로고    scopus 로고
    • Considerations for successful transplantation of encapsulated pancreatic islets
    • de Vos, P., Hamel, A.F., and Tatarkiewicz, K., 2002, Considerations for successful transplantation of encapsulated pancreatic islets. Diabetologia 45, 159-173.
    • (2002) Diabetologia , vol.45 , pp. 159-173
    • Vos, P.1    Hamel, A.F.2    Tatarkiewicz, K.3
  • 68
    • 0029780036 scopus 로고    scopus 로고
    • Normalization of diabetes in spontaneously diabetic cynomolgus monkeys by xenografts of microencapsulated porcine islets without immunosuppression
    • Sun, Y., Ma, X., Zhou, D., Vacek, I., and Sun, A.M., 1996, Normalization of diabetes in spontaneously diabetic cynomolgus monkeys by xenografts of microencapsulated porcine islets without immunosuppression. J. Clin. Invest. 98, 1417-1422.
    • (1996) J. Clin. Invest. , vol.98 , pp. 1417-1422
    • Sun, Y.1    Ma, X.2    Zhou, D.3    Vacek, I.4    Sun, A.M.5
  • 70
    • 0033009594 scopus 로고    scopus 로고
    • Synergistic effect of microencapsulation and immunoalteration on islet allograft survival in bioartificial pancreas
    • Zekorn, T.D., Horcher, A., Siebers, U., Federlin, K., and Bretzel, R.G., 1999, Synergistic effect of microencapsulation and immunoalteration on islet allograft survival in bioartificial pancreas. J. Mol. Med. 77, 193-198.
    • (1999) J. Mol. Med. , vol.77 , pp. 193-198
    • Zekorn, T.D.1    Horcher, A.2    Siebers, U.3    Federlin, K.4    Bretzel, R.G.5
  • 71
    • 0002712317 scopus 로고    scopus 로고
    • J.L. Platt, ed., ASM Press, Washington
    • Evans, R.W., 2001, In: Xenotransplantation (J.L. Platt, ed.), ASM Press, Washington, pp. 29-51.
    • (2001) Xenotransplantation , pp. 29-51
    • Evans, R.W.1
  • 72
    • 0026623093 scopus 로고
    • Identification of carbohydrate structures which bind human anti-porcine antibodies: Implications for discordant xenografting in man
    • Good, A.H., Cooper, D.K.C., and Malcolm, A.J. et al., 1992, Identification of carbohydrate structures which bind human anti-porcine antibodies: implications for discordant xenografting in man. Transplant. Proc. 24, 559-562.
    • (1992) Transplant. Proc. , vol.24 , pp. 559-562
    • Good, A.H.1    Cooper, D.K.C.2    Malcolm, A.J.3
  • 76
    • 0033512485 scopus 로고    scopus 로고
    • A critical role for human CD4+ T-cells in rejection of porcine islet cell xenografts
    • Friedman, T., Smith, R.N., Colvin, R.B., and Iacomini, J., 1999, A critical role for human CD4+ T-cells in rejection of porcine islet cell xenografts. Diabetes 48, 2340.
    • (1999) Diabetes , vol.48 , pp. 2340
    • Friedman, T.1    Smith, R.N.2    Colvin, R.B.3    Iacomini, J.4
  • 81
    • 4143081037 scopus 로고
    • Xenotransplantation of fetal porcine islet-like cell clusters in diabetes mellitus: An experimental and clinical study
    • Korsgren, O., 1991, Xenotransplantation of fetal porcine islet-like cell clusters in diabetes mellitus: an experimental and clinical study. Acta Univ. Upsal. 295, 1-40.
    • (1991) Acta Univ. Upsal. , vol.295 , pp. 1-40
    • Korsgren, O.1
  • 82
    • 0023837660 scopus 로고
    • Large-scale production of fetal porcine pancreatic islet-like cell clusters. An experimental tool for studies of islet cell differentiation and Xenotransplantation
    • Korsgren, O., Sandler, S., Landström, A., Jansson, L., Andersson, A., 1988, Large-scale production of fetal porcine pancreatic islet-like cell clusters. An experimental tool for studies of islet cell differentiation and Xenotransplantation. Transplantation 45, 509-514.
    • (1988) Transplantation , vol.45 , pp. 509-514
    • Korsgren, O.1    Sandler, S.2    Landström, A.3    Jansson, L.4    Andersson, A.5
  • 83
    • 0025811759 scopus 로고
    • Functional and morphological differentiation of fetal porcine islet-like cell clusters after transplantation into nude mice
    • Korsgren, O., Jansson, L., Eizirik, D., and Andersson, A., 1991, Functional and morphological differentiation of fetal porcine islet-like cell clusters after transplantation into nude mice. Diabetologia 34, 379-386.
    • (1991) Diabetologia , vol.34 , pp. 379-386
    • Korsgren, O.1    Jansson, L.2    Eizirik, D.3    Andersson, A.4
  • 84
    • 0025860840 scopus 로고
    • Persistent reversal of diabetes by transplantation of fetal pig proislets into nude mice
    • Liu, X., Federlin, K.F., Bretzel, R.G., Hering, B.J., and Brendel, M.D., 1991, Persistent reversal of diabetes by transplantation of fetal pig proislets into nude mice. Diabetes 40, 858-866.
    • (1991) Diabetes , vol.40 , pp. 858-866
    • Liu, X.1    Federlin, K.F.2    Bretzel, R.G.3    Hering, B.J.4    Brendel, M.D.5
  • 85
    • 0026729594 scopus 로고
    • Comparison of the potency of fetal pig pancreatic proislets and fragments to reverse diabetes
    • Liu, X., Brendel, M.D., Hering, B.J., Bretzel, R.G., and Federlin, K., 1992, Comparison of the potency of fetal pig pancreatic proislets and fragments to reverse diabetes. Transplant. Proc. 24, 987.
    • (1992) Transplant. Proc. , vol.24 , pp. 987
    • Liu, X.1    Brendel, M.D.2    Hering, B.J.3    Bretzel, R.G.4    Federlin, K.5
  • 88
    • 84989133016 scopus 로고
    • Cryopreservation transplantation and susceptibility to diabetogenic agents of fetal porcine proislets
    • Bretzel, R.G., Liu, X., Hering, B.J., Brendel, M., and Federlin, K., 1995, Cryopreservation transplantation and susceptibility to diabetogenic agents of fetal porcine proislets. Xenotransplantation 2, 133-138.
    • (1995) Xenotransplantation , vol.2 , pp. 133-138
    • Bretzel, R.G.1    Liu, X.2    Hering, B.J.3    Brendel, M.4    Federlin, K.5
  • 89
    • 0345628576 scopus 로고    scopus 로고
    • Fetal porcine islet-like cell clusters transplanted to cynomolgus monkeys: An immunohistochemical study
    • Soderlund, J., Wennberg, L., Castanos-Velez, E. et al., 1999, Fetal porcine islet-like cell clusters transplanted to cynomolgus monkeys: an immunohistochemical study. Transplantation 67, 784.
    • (1999) Transplantation , vol.67 , pp. 784
    • Soderlund, J.1    Wennberg, L.2    Castanos-Velez, E.3
  • 91
    • 0028072547 scopus 로고
    • Transplantation of porcine fetal pancreas to diabetic patients
    • Groth, C.G., Korsgren, O., Tibell, A. et al., 1994, Transplantation of porcine fetal pancreas to diabetic patients. Lancet 344, 1402-1404.
    • (1994) Lancet , vol.344 , pp. 1402-1404
    • Groth, C.G.1    Korsgren, O.2    Tibell, A.3
  • 92
    • 0031907868 scopus 로고
    • Uncertainty in Xenotransplantation: Individual benefit versus collective risk
    • Bach, F.H., Fishman, J.A., Daniels, N. et al., 1988, Uncertainty in Xenotransplantation: individual benefit versus collective risk. Nat. Med. 4, 141-144.
    • (1988) Nat. Med. , vol.4 , pp. 141-144
    • Bach, F.H.1    Fishman, J.A.2    Daniels, N.3
  • 93
    • 0031054438 scopus 로고    scopus 로고
    • Infection of human cells by an endogenous retrovirus of pigs
    • Patience, C., Takeuchi, Y., and Weiss, R.A., 1997, Infection of human cells by an endogenous retrovirus of pigs. Nat. Med. 3, 275-276.
    • (1997) Nat. Med. , vol.3 , pp. 275-276
    • Patience, C.1    Takeuchi, Y.2    Weiss, R.A.3
  • 94
    • 0032578311 scopus 로고    scopus 로고
    • Expression of pig endogenous retrovirus by primary porcine endothelial cells and infection of human cells
    • Martin, U., Kiessig, V., Blusch, J.H., Haverich, A., von der Helm, K., Herden, T., and Steinhoff, G., 1998, Expression of pig endogenous retrovirus by primary porcine endothelial cells and infection of human cells. Lancet 352, 666-667.
    • (1998) Lancet , vol.352 , pp. 666-667
    • Martin, U.1    Kiessig, V.2    Blusch, J.H.3    Haverich, A.4    Von Der Helm, K.5    Herden, T.6    Steinhoff, G.7
  • 95
    • 0034618653 scopus 로고    scopus 로고
    • Infection by porcine endogenous retroviruses after islet Xenotransplantation in SCID mice
    • Van der Laan, L.J., Lockey, C., Griffeth, B.C. et al., 2000, Infection by porcine endogenous retroviruses after islet Xenotransplantation in SCID mice. Nature 407, 90-94.
    • (2000) Nature , vol.407 , pp. 90-94
    • Van Der Laan, L.J.1    Lockey, C.2    Griffeth, B.C.3
  • 96
    • 0034667748 scopus 로고    scopus 로고
    • Transmission of porcine endogenous retroviruses in severe combined immunodeficient mice xenotransplanted with fetal porcine pancreatic cells
    • Deng, Y.M., Tuch, B.E., and Rawlinson, W.D., 2000, Transmission of porcine endogenous retroviruses in severe combined immunodeficient mice xenotransplanted with fetal porcine pancreatic cells. Transplantation 70, 1010-1016.
    • (2000) Transplantation , vol.70 , pp. 1010-1016
    • Deng, Y.M.1    Tuch, B.E.2    Rawlinson, W.D.3
  • 97
    • 0032578251 scopus 로고    scopus 로고
    • No evidence of infection with porcine endogenous retrovirus in recipients of porcine islet-cell xenografts
    • Heneine, W., Tibell, A., Switzer, W.M. et al., 1998, No evidence of infection with porcine endogenous retrovirus in recipients of porcine islet-cell xenografts. Lancet 352, 695-699.
    • (1998) Lancet , vol.352 , pp. 695-699
    • Heneine, W.1    Tibell, A.2    Switzer, W.M.3
  • 98
    • 0033588002 scopus 로고    scopus 로고
    • Search for cross-species transmission of porcine endogenous retrovirus in patients treated with living pig tissue
    • Paradis, K., Langford, G., Long, Z. et al., 1999, Search for cross-species transmission of porcine endogenous retrovirus in patients treated with living pig tissue. Science 285, 1236-1241.
    • (1999) Science , vol.285 , pp. 1236-1241
    • Paradis, K.1    Langford, G.2    Long, Z.3
  • 99
    • 0035057914 scopus 로고    scopus 로고
    • From stem cells to beta cells: New strategies in cell therapy of diabetes mellitus
    • Soria, B., Skoudy, A., and Martin, F., 2001, From stem cells to beta cells: new strategies in cell therapy of diabetes mellitus. Diabetologia 44, 407-415.
    • (2001) Diabetologia , vol.44 , pp. 407-415
    • Soria, B.1    Skoudy, A.2    Martin, F.3
  • 100
    • 0031738115 scopus 로고
    • Transcribing the pancreas
    • Edlund, H., 1958, Transcribing the pancreas. Diabetes 47, 1817-1823.
    • (1958) Diabetes , vol.47 , pp. 1817-1823
    • Edlund, H.1
  • 101
    • 0031031571 scopus 로고    scopus 로고
    • Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
    • Stoffers, D.A., Zinkin, N.T., Stanojevic, V., Clarke, W.L., and Habener, J.F., 1997, Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nat. Genet. 15, 106-110.
    • (1997) Nat. Genet. , vol.15 , pp. 106-110
    • Stoffers, D.A.1    Zinkin, N.T.2    Stanojevic, V.3    Clarke, W.L.4    Habener, J.F.5
  • 103
    • 0034652287 scopus 로고    scopus 로고
    • Neurogenin 3 is required for the development of the four endocrine cell lineages of the pancreas
    • Gradwohl, G., Dierich, A., Le Meur, M., and Guillemot, F., 2000, Neurogenin 3 is required for the development of the four endocrine cell lineages of the pancreas. Proc. Natl. Acad. Sci. USA 97, 1607-1611.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 1607-1611
    • Gradwohl, G.1    Dierich, A.2    Le Meur, M.3    Guillemot, F.4
  • 104
    • 0030897629 scopus 로고    scopus 로고
    • The Pax 4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas
    • Sosa-Pineda, B., Chowdhury, K., Torres, M., Oliver, G., and Gruss, P., 1997, The Pax 4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas. Nature 386, 399-402.
    • (1997) Nature , vol.386 , pp. 399-402
    • Sosa-Pineda, B.1    Chowdhury, K.2    Torres, M.3    Oliver, G.4    Gruss, P.5
  • 105
    • 0033979603 scopus 로고    scopus 로고
    • Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice
    • Soria, B., Roche, E., Berna, G., Leon-Quinto, T., Reig, J.A., and Martin, F., 2000, Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice. Diabetes 49, 157-162.
    • (2000) Diabetes , vol.49 , pp. 157-162
    • Soria, B.1    Roche, E.2    Berna, G.3    Leon-Quinto, T.4    Reig, J.A.5    Martin, F.6
  • 106
    • 0035906902 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets
    • Lumelsky, N., Blondel, O., Laeng, P., Velasco, I., Ravin, R., and McKay, R., 2001, Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 292, 1389-1394.
    • (2001) Science , vol.292 , pp. 1389-1394
    • Lumelsky, N.1    Blondel, O.2    Laeng, P.3    Velasco, I.4    Ravin, R.5    McKay, R.6
  • 108
    • 0035119871 scopus 로고    scopus 로고
    • Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes
    • Zulewski, H., Abraham, E.J., Gerlach, M.J., Daniel, P.B., Moritz, W., Muller, B., Vallejo, M., Thomas, M.K., and Habener, J.F., 2001, Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes. Diabetes 50, 521-533.
    • (2001) Diabetes , vol.50 , pp. 521-533
    • Zulewski, H.1    Abraham, E.J.2    Gerlach, M.J.3    Daniel, P.B.4    Moritz, W.5    Muller, B.6    Vallejo, M.7    Thomas, M.K.8    Habener, J.F.9
  • 109
    • 0034100823 scopus 로고    scopus 로고
    • Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells
    • Ramiya, V.K., Maraist, M., Arfors, K.E., Schatz, D.A., Peck, A.B., and Cornelius, J.G., 2000, Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells. Nat. Med. 6, 278-282.
    • (2000) Nat. Med. , vol.6 , pp. 278-282
    • Ramiya, V.K.1    Maraist, M.2    Arfors, K.E.3    Schatz, D.A.4    Peck, A.B.5    Cornelius, J.G.6
  • 113
    • 0034707028 scopus 로고    scopus 로고
    • Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogue
    • Lee, H.C., Kim, S.J., Kim, K.S., Shin, H.C., and Yoon, J.W., 2000, Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogue. Nature 408, 483-488.
    • (2000) Nature , vol.408 , pp. 483-488
    • Lee, H.C.1    Kim, S.J.2    Kim, K.S.3    Shin, H.C.4    Yoon, J.W.5
  • 114
    • 0036124978 scopus 로고    scopus 로고
    • Secretion of bioactive human insulin following plasmid-mediated gene transfer to non-neuroendocrine cell lines, primary cultures and rat skeletal muscle in vivo
    • Shaw, J.A.M., Delday, M.I., Hart, A.W., and Docherty, K., 2002, Secretion of bioactive human insulin following plasmid-mediated gene transfer to non-neuroendocrine cell lines, primary cultures and rat skeletal muscle in vivo. J. Endocrinol. 172, 653-672.
    • (2002) J. Endocrinol. , vol.172 , pp. 653-672
    • Shaw, J.A.M.1    Delday, M.I.2    Hart, A.W.3    Docherty, K.4
  • 115
    • 0036314659 scopus 로고    scopus 로고
    • Counteraction of type 1 diabetic alterations by engineering skeletal muscle to produce insulin: Insights from transgenic mice
    • Riu, E., Mas, A., Ferre, T., Pujol, A., Gros, L., Otaegui, P., Montoliu, L., and Bosch, F., 2002, Counteraction of type 1 diabetic alterations by engineering skeletal muscle to produce insulin: insights from transgenic mice. Diabetes 51, 704-711.
    • (2002) Diabetes , vol.51 , pp. 704-711
    • Riu, E.1    Mas, A.2    Ferre, T.3    Pujol, A.4    Gros, L.5    Otaegui, P.6    Montoliu, L.7    Bosch, F.8
  • 116
    • 0034068602 scopus 로고    scopus 로고
    • Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia
    • Ferber, S., Halkin, A., Cohen, H., Ber, I., Einav, Y., Goldberg, I., Barshack, I., Seijfers, R., Kopolovic, J., Kaiser, N., and Karasik, A., 2000, Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia. Nat. Med 6, 568-572.
    • (2000) Nat. Med , vol.6 , pp. 568-572
    • Ferber, S.1    Halkin, A.2    Cohen, H.3    Ber, I.4    Einav, Y.5    Goldberg, I.6    Barshack, I.7    Seijfers, R.8    Kopolovic, J.9    Kaiser, N.10    Karasik, A.11
  • 117
    • 0034071364 scopus 로고    scopus 로고
    • Converting hepatocytes to E-cells - A new approach for diabetes?
    • Kahn, A., 2000, Converting hepatocytes to E-cells - a new approach for diabetes? Nat. Med. 6, 505-506.
    • (2000) Nat. Med. , vol.6 , pp. 505-506
    • Kahn, A.1
  • 118
    • 0030741524 scopus 로고    scopus 로고
    • Scientific and political impediment to successful islet transplantation
    • Weir, G.C., and Bonner-Weir, S., 1997, Scientific and political impediment to successful islet transplantation. Diabetes 46, 1247-1256.
    • (1997) Diabetes , vol.46 , pp. 1247-1256
    • Weir, G.C.1    Bonner-Weir, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.