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Volumn 172, Issue 6, 2004, Pages 3814-3821

Aberrant Toll Receptor Expression and Endotoxin Hypersensitivity in Mice Lacking a Functional TGF-β1 Signaling Pathway

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CYTOKINE; ENDOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; SMAD3 PROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

EID: 1542514714     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.6.3814     Document Type: Article
Times cited : (91)

References (43)
  • 3
    • 0034600070 scopus 로고    scopus 로고
    • Disruption of T cell homeostasis in mice expressing a T cell-specific dominant negative transforming growth factor β II receptor
    • Lucas, P. J., S. J. Kim, S. J. Melby, and R. E. Gress. 2000. Disruption of T cell homeostasis in mice expressing a T cell-specific dominant negative transforming growth factor β II receptor. J. Exp. Med. 191:1187.
    • (2000) J. Exp. Med. , vol.191 , pp. 1187
    • Lucas, P.J.1    Kim, S.J.2    Melby, S.J.3    Gress, R.E.4
  • 4
    • 0034131557 scopus 로고    scopus 로고
    • Abrogation of TGFβ signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
    • Gorelik, L., and R. A. Flavell. 2000. Abrogation of TGFβ signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity 12:171.
    • (2000) Immunity , vol.12 , pp. 171
    • Gorelik, L.1    Flavell, R.A.2
  • 5
    • 0034924028 scopus 로고    scopus 로고
    • Loss of transforming growth factor β signalling in the intestine contributes to tissue injury in inflammatory bowel disease
    • Hahm, K. B., Y. H. Im, T. W. Parks, S. H. Park, S. Markowitz, H. Y. Jung, J. Green, and S. J. Kim. 2001. Loss of transforming growth factor β signalling in the intestine contributes to tissue injury in inflammatory bowel disease. Gut 49:190.
    • (2001) Gut , vol.49 , pp. 190
    • Hahm, K.B.1    Im, Y.H.2    Parks, T.W.3    Park, S.H.4    Markowitz, S.5    Jung, H.Y.6    Green, J.7    Kim, S.J.8
  • 6
    • 0033104503 scopus 로고    scopus 로고
    • Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-β
    • Yang, X., J. J. Letterio, R. J. Lechleider, L. Chen, R. Hayman, H. Gu, A. B. Roberts, and C. Deng. 1999. Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-β. EMBO J. 18:1280.
    • (1999) EMBO J. , vol.18 , pp. 1280
    • Yang, X.1    Letterio, J.J.2    Lechleider, R.J.3    Chen, L.4    Hayman, R.5    Gu, H.6    Roberts, A.B.7    Deng, C.8
  • 7
    • 0029952226 scopus 로고    scopus 로고
    • Spontaneously increased production of nitric oxide and aberrant expression of the inducible nitric oxide synthase in vivo in the transforming growth factor β1 null mouse
    • Vodovotz, Y., A. G. Geiser, L. Chesler, J. J. Letterio, A. Campbell, M. S. Lucia, M. B. Sporn, and A. B. Roberts. 1996. Spontaneously increased production of nitric oxide and aberrant expression of the inducible nitric oxide synthase in vivo in the transforming growth factor β1 null mouse. J. Exp. Med. 183:2337.
    • (1996) J. Exp. Med. , vol.183 , pp. 2337
    • Vodovotz, Y.1    Geiser, A.G.2    Chesler, L.3    Letterio, J.J.4    Campbell, A.5    Lucia, M.S.6    Sporn, M.B.7    Roberts, A.B.8
  • 8
    • 0037111393 scopus 로고    scopus 로고
    • Dysregulation of IFN-γ signaling pathways in the absence of TGF-β1
    • McCartney-Francis, N. L., and S. M. Wahl. 2002. Dysregulation of IFN-γ signaling pathways in the absence of TGF-β1. J. Immunol. 169:5941.
    • (2002) J. Immunol. , vol.169 , pp. 5941
    • McCartney-Francis, N.L.1    Wahl, S.M.2
  • 9
    • 0036781052 scopus 로고    scopus 로고
    • NF-κB regulation in the immune system
    • Li, Q., and I. M. Verma. 2002. NF-κB regulation in the immune system. Nat. Rev. Immunol. 2:725.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 725
    • Li, Q.1    Verma, I.M.2
  • 10
    • 0031906550 scopus 로고    scopus 로고
    • Signal transduction through NF-κB
    • May, M. J., and S. Ghosh. 1998. Signal transduction through NF-κB. Immunol. Today 19:80.
    • (1998) Immunol. Today , vol.19 , pp. 80
    • May, M.J.1    Ghosh, S.2
  • 11
    • 0035164415 scopus 로고    scopus 로고
    • Toll-like receptor-mediated NF-κB activation: A phylogenetically conserved paradigm in innate immunity
    • Zhang, G., and S. Ghosh. 2001. Toll-like receptor-mediated NF-κB activation: a phylogenetically conserved paradigm in innate immunity. J. Clin. Invest. 107:13.
    • (2001) J. Clin. Invest. , vol.107 , pp. 13
    • Zhang, G.1    Ghosh, S.2
  • 12
    • 17544365995 scopus 로고    scopus 로고
    • The IκB/NF-κB system: A key determinant of mucosal inflammation and protection
    • Jobin, C., and R. B. Sartor. 2000. The IκB/NF-κB system: a key determinant of mucosal inflammation and protection. Am. J. Physiol. 278:C451.
    • (2000) Am. J. Physiol. , vol.278
    • Jobin, C.1    Sartor, R.B.2
  • 13
    • 0029563524 scopus 로고
    • Nuclear factor-κB in rheumatoid synovium: Localization of p50 and p65
    • Handel, M. L., L. B. McMorrow, and E. M. Gravallese. 1995. Nuclear factor-κB in rheumatoid synovium: localization of p50 and p65. Arthritis Rheum. 38:1762.
    • (1995) Arthritis Rheum. , vol.38 , pp. 1762
    • Handel, M.L.1    McMorrow, L.B.2    Gravallese, E.M.3
  • 15
    • 0034307339 scopus 로고    scopus 로고
    • The Toll receptor family and microbial recognition
    • Medzhitov, R., and C. Janeway, Jr. 2000. The Toll receptor family and microbial recognition. Trends Microbiol. 8:452.
    • (2000) Trends Microbiol. , vol.8 , pp. 452
    • Medzhitov, R.1    Janeway Jr., C.2
  • 17
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov, R., P. Preston-Hurlburt, and C. A. Janeway, Jr. 1997. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388:394.
    • (1997) Nature , vol.388 , pp. 394
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr., C.A.3
  • 20
    • 0033213590 scopus 로고    scopus 로고
    • Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components
    • Takeuchi, O., K. Hoshino, T. Kawai, H. Sanjo, H. Takada, T. Ogawa, K. Takeda, and S. Akira. 1999. Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components. Immunity 11:443.
    • (1999) Immunity , vol.11 , pp. 443
    • Takeuchi, O.1    Hoshino, K.2    Kawai, T.3    Sanjo, H.4    Takada, H.5    Ogawa, T.6    Takeda, K.7    Akira, S.8
  • 23
    • 0037405946 scopus 로고    scopus 로고
    • Rapid tumor formation of human T-cell leukemia virus type 1-infected cell lines in novel NOD-SCID/ γc(null) mice: Suppression by an inhibitor against NF-κB
    • Dewan, M. Z., K. Terashima, M. Taruishi, H. Hasegawa, M. Ito, Y. Tanaka, N. Mori, T. Sata, Y. Koyanagi, M. Maeda, et al. 2003. Rapid tumor formation of human T-cell leukemia virus type 1-infected cell lines in novel NOD-SCID/ γc(null) mice: suppression by an inhibitor against NF-κB. J. Virol. 77:5286.
    • (2003) J. Virol. , vol.77 , pp. 5286
    • Dewan, M.Z.1    Terashima, K.2    Taruishi, M.3    Hasegawa, H.4    Ito, M.5    Tanaka, Y.6    Mori, N.7    Sata, T.8    Koyanagi, Y.9    Maeda, M.10
  • 24
    • 0034292329 scopus 로고    scopus 로고
    • Impaired IFN-γ production in IFN regulatory factor-1 knockout mice during endotoxemia is secondary to a loss of both IL-12 and IL-12 receptor expression
    • Salkowski, C. A., K. E. Thomas, M. J. Cody, and S. N. Vogel. 2000. Impaired IFN-γ production in IFN regulatory factor-1 knockout mice during endotoxemia is secondary to a loss of both IL-12 and IL-12 receptor expression. J. Immunol. 165:3970.
    • (2000) J. Immunol. , vol.165 , pp. 3970
    • Salkowski, C.A.1    Thomas, K.E.2    Cody, M.J.3    Vogel, S.N.4
  • 27
    • 0042847104 scopus 로고    scopus 로고
    • The proteasome as a lipopolysaccharide-binding protein in macrophages: Differential effects of proteasome inhibition on lipopolysaccharide-induced signaling events
    • Qureshi, N., P. Y. Perera, J. Shen, G. Zhang, A. Lenschat, G. Splitter, D. C. Morrison, and S. N. Vogel. 2003. The proteasome as a lipopolysaccharide-binding protein in macrophages: differential effects of proteasome inhibition on lipopolysaccharide-induced signaling events. J. Immunol. 171:1515.
    • (2003) J. Immunol. , vol.171 , pp. 1515
    • Qureshi, N.1    Perera, P.Y.2    Shen, J.3    Zhang, G.4    Lenschat, A.5    Splitter, G.6    Morrison, D.C.7    Vogel, S.N.8
  • 28
    • 0036067659 scopus 로고    scopus 로고
    • Toll receptors, CD14, and macrophage activation and deactivation by LPS
    • Dobrovolskaia, M. A., and S. N. Vogel. 2002. Toll receptors, CD14, and macrophage activation and deactivation by LPS. Microbes Infect. 4:903.
    • (2002) Microbes Infect. , vol.4 , pp. 903
    • Dobrovolskaia, M.A.1    Vogel, S.N.2
  • 29
    • 0038447123 scopus 로고    scopus 로고
    • Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock
    • Van Amersfoort, E. S., T. J. Van Berkel, and J. Kuiper. 2003. Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock. Clin. Microbiol. Rev. 16:379.
    • (2003) Clin. Microbiol. Rev. , vol.16 , pp. 379
    • Van Amersfoort, E.S.1    Van Berkel, T.J.2    Kuiper, J.3
  • 33
    • 0037071251 scopus 로고    scopus 로고
    • Relevance of mutations in the TLR4 receptor in patients with Gram-negative septic shock
    • Lorenz, E., J. P. Mira, K. L. Frees, and D. A. Schwartz. 2002. Relevance of mutations in the TLR4 receptor in patients with Gram-negative septic shock. Arch. Intern. Med. 162:1028.
    • (2002) Arch. Intern. Med. , vol.162 , pp. 1028
    • Lorenz, E.1    Mira, J.P.2    Frees, K.L.3    Schwartz, D.A.4
  • 35
    • 0033931495 scopus 로고    scopus 로고
    • Toll-like receptor 4-deficient mice have reduced bone destruction, following mixed anaerobic infection
    • Hou, L., H. Sasaki, and P. Stashenko. 2000. Toll-like receptor 4-deficient mice have reduced bone destruction, following mixed anaerobic infection. Infect. Immun. 68:4681.
    • (2000) Infect. Immun. , vol.68 , pp. 4681
    • Hou, L.1    Sasaki, H.2    Stashenko, P.3
  • 36
    • 0036358166 scopus 로고    scopus 로고
    • TGF-β: Receptors, signaling pathways and autoimmunity
    • Chen, W., and S. M. Wahl. 2002. TGF-β: receptors, signaling pathways and autoimmunity. Curr. Dir. Autoimmun. 5:62.
    • (2002) Curr. Dir. Autoimmun. , vol.5 , pp. 62
    • Chen, W.1    Wahl, S.M.2
  • 39
    • 0034891224 scopus 로고    scopus 로고
    • TGF-β/Smad signaling defects in inflammatory bowel disease: Mechanisms and possible novel therapies for chronic inflammation
    • Fiocchi, C. 2001. TGF-β/Smad signaling defects in inflammatory bowel disease: mechanisms and possible novel therapies for chronic inflammation. J. Clin. Invest. 108:523.
    • (2001) J. Clin. Invest. , vol.108 , pp. 523
    • Fiocchi, C.1
  • 43
    • 0036780681 scopus 로고    scopus 로고
    • Toll-like receptors as potential therapeutic targets for multiple diseases
    • Zuany-Amorim, C., J. Hastewell, and C. Walker. 2002. Toll-like receptors as potential therapeutic targets for multiple diseases. Nat. Rev. Drug Discov. 1:797.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 797
    • Zuany-Amorim, C.1    Hastewell, J.2    Walker, C.3


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