Lactose-conjugated polyion complex micelles incorporating plasmid DNA as a targetable gene vector system: Their preparation and gene transfecting efficiency against cultured HepG2 cells

Journal of Controlled Release

Volumn 95, Issue 3, 2004, Pages 653-664

  Wakebayashi, Daisuke ^a   Nishiyama, Nobuhiro ^a,b   Yamasaki, Yuichi ^a   Itaka, Keiji ^a,c   Kanayama, Naoki ^a   Harada, Atsushi ^a   Nagasaki, Yukio ^d   Kataoka, Kazunori ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Block copolymer; Lactose; Non viral gene vector; Plasmid DNA; Polyion complex micelle

Indexed keywords

BLOCK COPOLYMERS; CELL CULTURE; DNA; ENZYMES; GENES; MICELLES; PRECIPITATION (CHEMICAL);

CELLULAR UPTAKE; GENE VECTOR SYSTEM;

CARBOHYDRATES;

ALPHA LACTOSYL POLY(ETHYLENE GLYCOL) POLY[2 (DIMETHYLAMINO)ETHYL METHACRYLATE]; ASIALOFETUIN; ASIALOGLYCOPROTEIN RECEPTOR; BETA GALACTOSIDASE; PLASMID DNA; POLYMER; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CELL CULTURE; ENDOCYTOSIS; GENE VECTOR; GENETIC TRANSFECTION; HEPATOMA CELL; HUMAN; HUMAN CELL; MICELLE; PRIORITY JOURNAL;

CELL LINE, TUMOR; DNA; DRUG EVALUATION, PRECLINICAL; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; LACTOSE; LIVER NEOPLASMS; MICELLES; PLASMIDS; POLYETHYLENE GLYCOLS; TRANSFECTION;

EID: 1542509565     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2004.01.003     Document Type: Article

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