Mutagenesis Studies toward Understanding the Mechanism of Differential Reactivity of Factor Xa with the Native and Heparin-Activated Antithrombin

Biochemistry

Volumn 43, Issue 10, 2004, Pages 2898-2905

  Rezaie, Alireza R ^a   Yang, Likui ^a   Manithody, Chandrashekhara ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; CONFORMATIONS; MUTAGENESIS; PROTEINS; REACTION KINETICS;

MUTANTS;

BIOCHEMISTRY;

ANTITHROMBIN; ARGININE; BLOOD CLOTTING FACTOR 10A; HEPARIN DERIVATIVE; PENTASACCHARIDE; PROTEINASE; SERINE PROTEINASE INHIBITOR; SODIUM;

ARTICLE; COMPLEX FORMATION; INHIBITION KINETICS; MICHAELIS MENTEN KINETICS; MOLECULAR MODEL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; REACTION ANALYSIS; SIGNAL TRANSDUCTION;

AMINO ACID SUBSTITUTION; ANTITHROMBINS; BLOOD COAGULATION TESTS; CELL LINE; CHROMOGENIC COMPOUNDS; FACTOR X; FACTOR XA; HEPARIN; HUMANS; HYDROLYSIS; KINETICS; MUTAGENESIS, SITE-DIRECTED; OLIGOSACCHARIDES; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 1542327646     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi036145a     Document Type: Article

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