Calcium enhances heparin catalysis of the antithrombin-factor Xa reaction by a template mechanism: Evidence that calcium alleviates Gla domain antagonism of heparin binding to factor Xa

Journal of Biological Chemistry

Volumn 273, Issue 27, 1998, Pages 16824-16827

  Rezaie, Alireza R ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBIN; BLOOD CLOTTING FACTOR 10A; CALCIUM; HEPARIN;

ANTICOAGULATION; ARTICLE; CALCIUM BINDING; CATALYSIS; CONFORMATIONAL TRANSITION; DRUG BINDING; DRUG EFFECT; DRUG MECHANISM; ENZYME INACTIVATION; HUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

ANTITHROMBIN III; CALCIUM; CATALYSIS; FACTOR XA; HEPARIN; HUMANS; KINETICS; PROTEIN BINDING; RECOMBINANT PROTEINS;

EID: 0032479424     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.27.16824     Document Type: Article

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