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Volumn 277, Issue 27, 2002, Pages 24460-24465
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Elimination of P1 arginine 393 interaction with underlying glutamic acid 255 partially activates antithrombin III for thrombin inhibition but not factor Xa inhibition
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Author keywords
[No Author keywords available]
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Indexed keywords
CHEMICAL ACTIVATION;
HYDROGEN BONDS;
MUTAGENESIS;
PROTEINS;
HYPOTHESIS;
BIOCHEMISTRY;
ANTITHROMBIN III;
ARGININE;
BLOOD CLOTTING FACTOR 10A;
GLUTAMIC ACID;
HEPARIN;
PENTASACCHARIDE;
THROMBIN;
AMINO ACID SUBSTITUTION;
ARTICLE;
BINDING AFFINITY;
CATALYSIS;
CONFORMATIONAL TRANSITION;
ENZYME INHIBITION;
HYDROGEN BOND;
MOLECULAR INTERACTION;
PRIORITY JOURNAL;
AMINO ACID SEQUENCE;
AMINO ACID SUBSTITUTION;
ANIMALS;
ANTITHROMBIN III;
ARGININE;
BASE SEQUENCE;
BINDING SITES;
CELL LINE;
FACTOR XA;
GLUTAMIC ACID;
HEPARIN;
HUMANS;
MODELS, MOLECULAR;
MUTAGENESIS, SITE-DIRECTED;
POLYMERASE CHAIN REACTION;
PROTEIN CONFORMATION;
RECOMBINANT PROTEINS;
SPODOPTERA;
THROMBIN;
TRANSFECTION;
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EID: 0037025340
PISSN: 00219258
EISSN: None
Source Type: Journal
DOI: 10.1074/jbc.M203127200 Document Type: Article |
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Times cited : (17)
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References (26)
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