Ritonavir and dexamethasone induce expression of CYP3A and P-glycoprotein in rats

Xenobiotica

Volumn 34, Issue 2, 2004, Pages 133-150

  Perloff, M D ^a   Von Moltke, L L ^a   Greenblatt, D J ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A; DEXAMETHASONE; DRUG METABOLITE; GLYCOPROTEIN P; ISOENZYME; PROTEINASE INHIBITOR; RITONAVIR; TRIAZOLAM;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG CLEARANCE; DRUG EFFECT; DRUG EXPOSURE; DRUG HYDROXYLATION; DRUG METABOLISM; DRUG POTENCY; DUODENUM; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INDUCTION; FEEDING; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNOREACTIVITY; IN VITRO STUDY; INTESTINE MUCOSA; LIVER; LIVER MICROSOME; LONG TERM EXPOSURE; MALE; MICROVASCULATURE; MUCOSA CELL; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RAT; REACTION TIME; RODENT;

ALGORITHMS; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIBODIES, BLOCKING; ARYL HYDROCARBON HYDROXYLASES; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; CAPILLARIES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 CYP3A; DEXAMETHASONE; ENZYME INDUCTION; ENZYME INHIBITORS; GABA MODULATORS; GENE EXPRESSION; HIV PROTEASE INHIBITORS; INTESTINES; LIVER; LUMINESCENT MEASUREMENTS; MALE; MICROSOMES; OXIDOREDUCTASES, N-DEMETHYLATING; P-GLYCOPROTEIN; RATS; RATS, SPRAGUE-DAWLEY; RITONAVIR; TRIAZOLAM;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; RODENTIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 1542314451     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/00498250310001630215     Document Type: Article

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