Characterization of Six in vitro Reactions Mediated by Human Cytochrome P450: Application to the Testing of Cytochrome P450-Directed Antibodies

Pharmacology

Volumn 52, Issue 2, 1996, Pages 125-134

  Schmider, Jürgen ^a   Greenblatt, David J ^a   von Moltke, Lisa L ^a   Harmatz, Jerold S ^a   Duan, Su X ^a   Karsov, Dmitry ^a   Shader, Richard I ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acetaminophen; Alprazolam; Chlorzoxazone; CYP1A1 2; CYP2C19; CYP2C9; CYP2D6; CYP2E1; CYP3A3 4; Cytochrome P450; Dextromethorphan; Dextrorphan; Immunoinhibition; Metabolism in vitro; Monoclonal antibody; Phenacetin; Phenytoin; Polyclonal antibody; S Mephenytoin

Indexed keywords

ALPRAZOLAM; CHLORZOXAZONE; CYTOCHROME P450; DEXTROMETHORPHAN; DEXTRORPHAN; ENZYME ANTIBODY; ISOENZYME; PARACETAMOL; PHENACETIN; PHENYTOIN;

ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; ENZYME INHIBITION; ENZYME MECHANISM; HUMAN; NORMAL HUMAN; PRIORITY JOURNAL;

EID: 0030041594     PISSN: 00317012     EISSN: 14230313     Source Type: Journal    
DOI: 10.1159/000139376     Document Type: Article

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