Effects of age on in vitro midazolam biotransformation in male CD-1 mouse liver microsomes

Journal of Pharmacology and Experimental Therapeutics

Volumn 292, Issue 3, 2000, Pages 1024-1031

  Warrington, Jill S ^a   Poku, Joseph W ^a   Von Moltke, Lisa L ^a   Shader, Richard I ^a   Harmatz, Jerold S ^a   Greenblatt, David J ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA HYDROXYMIDAZOLAM; ALPRAZOLAM; CYTOCHROME P450 3A; KETOCONAZOLE; MIDAZOLAM; POLYCLONAL ANTIBODY;

AGING; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; DRUG TRANSFORMATION; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; LIVER MICROSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

AGE FACTORS; ALPRAZOLAM; ANIMALS; ANTI-ANXIETY AGENTS; ARYL HYDROCARBON HYDROXYLASES; BIOTRANSFORMATION; BLOTTING, WESTERN; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; KETOCONAZOLE; MALE; MICE; MICROSOMES, LIVER; MIDAZOLAM; OXIDOREDUCTASES, N-DEMETHYLATING;

EID: 0034050290     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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