Side-chain flexibility in protein-ligand binding: The minimal rotation hypothesis

Protein Science

Volumn 14, Issue 4, 2005, Pages 1104-1114

  Zavodszky, Maria I ^a   Kuhn, Leslie A ^a,b  

^a Michigan State University   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

angles; Conformational sampling; Docking; Flexibility; Induced fit; Side chain rotamers; SLIDE; Stereochemistry

Indexed keywords

LIGAND; PROTEIN;

ARTICLE; COMPUTER PROGRAM; CONFORMATIONAL TRANSITION; ENERGY; HYPOTHESIS; LIGAND BINDING; MODEL; MOTION; PREDICTION; PRIORITY JOURNAL; ROTATION; STEREOCHEMISTRY;

AMINO ACIDS; BINDING SITES; GLUTATHIONE TRANSFERASE; LIGANDS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEINS; ROTATION; SOFTWARE; THROMBIN;

EID: 15244353539     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.041153605     Document Type: Article

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