Effects of IL-12 and IL-18 on HBcAg-specific cytokine production by CD4 T lymphocytes of children with chronic hepatitis B infection

Antiviral Research

Volumn 66, Issue 1, 2005, Pages 23-27

  Szkaradkiewicz, Andrzej ^a   Jopek, Aleksandra ^a   Wysocki, Jacek ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Hepatitis B virus; Interferon ; Interleukin 12; Interleukin 18; Th lymphocytes

Indexed keywords

GAMMA INTERFERON; HEPATITIS B CORE ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 18 BINDING PROTEIN; INTERLEUKIN 4; INTERLEUKIN 5;

ADOLESCENT; ANTIGEN SPECIFICITY; ARTICLE; CELL ISOLATION; CHILD; CHRONIC HEPATITIS; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; HEPATITIS B; HUMAN; HUMAN CELL; LYMPHOCYTE CULTURE; MALE; PRIORITY JOURNAL; T LYMPHOCYTE;

HEPATITIS B VIRUS;

EID: 15244343352     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.antiviral.2004.12.005     Document Type: Article

References (23)

1. V.J. Cavanaugh, L.G. Guidotti, and F.V. Chisari Interleukin-12 inhibits hepatitis B virus replication in transgenic mice J. Virol. 71 1997 3236 3243
2. F.V. Chisari, and C. Ferrari Hepatitis B virus immunopathogenesis Annu. Rev. Immunol. 13 1995 29 60
3. G.E.B. El Ghazali, S. Paulie, G. Andersson, Y. Hansson, G. Holmquist, J.-B. Sun, T. Olsson, H.-P. Ekre, and M. Troye-Blomberg Number of interleukin-4 and interferon-γ-secreting human T cells reactive with tetanus toxoid and the mycobacterial antigen PPD or phytohemagglutinin: distinct response profiles depending on the type of antigen used for activation Eur. J. Immunol. 23 1993 2740 2745
4. S. Funderud, K. Nustad, T. Lea, F. Vartdal, G. Gaudernack, P. Stenstad, and J. Ugelstad Fractionation of lymphocytes by immunomagnetic beads G.G.B. Klaus Lymphocytes: a Practical Approach 1987 IRL Press Oxford 55 65
5. L.G. Guidotti, K. Ando, M.V. Hobbs, T. Ishikawa, L. Runkel, R.D. Schreiber, and F.V. Chisari Cytotoxic T lymphocytes inhibit hepatitis B virus gene expression by a noncytolytic mechanism in transgenic mice Proc. Natl. Acad. Sci. U.S.A. 91 1994 3764 3768
6. L.G. Guidotti, R. Rochford, J. Chung, M. Shapiro, R. Purcell, and F.V. Chisari Viral clearance without destruction of infected cells during acute HBV infection Science 284 1999 825 829
7. C.A. Hunter, and S.L. Reiner Cytokines and T cells in host defense Curr. Opin. Immunol. 12 2000 413 418
8. M.-C. Jung, B. Hartmann, J.-T. Gerlach, H. Diepolder, R. Gruber, W. Schraut, N. Grüner, R. Zachoval, R. Hoffmann, T. Santantonio, M. Wächtler, and G.R. Pape Virus-specific lymphokine production differs quantitatively but not qualitatively in acute and chronic hepatitis B infection Virology 261 1999 165 172
9. K. Kohno, J. Kataoka, T. Otsuki, Y. Suemoto, I. Okamoto, M. Usui, M. Ikeda, and M. Kurimoto IFN-γ-inducing factor (IGIF) is a costimulatory factor on the activation of Th1, but not Th2 cells and exerts its effect independently of IL-12 J. Immunol. 158 1997 1541 1550
10. M.J. Koziel Cytokines in viral hepatitis Semin. Liver Dis. 19 1999 157 169
11. + T cells and hepatitis B virus clearance in chronic heaptitis with or without hepatitis B e-minus hepatitis B virus mutants Hepatology 22 1995 61 68
12. K.J. Maloy, and F. Powrie Regulatory T cells in the control of immune pathology Nat. Immunol. 2 2001 816 822
13. L. Meyaard, E. Hovenkamp, S.A. Otto, and F. Miedema IL-12-induced IL-10 production by human T cells as a negative feedback for IL-12-induced immune responses J. Immunol. 156 1996 2776 2782
14. D.R. Milich, F. Schödel, J.L. Hughes, J.E. Jones, and D.L. Peterson The hepatitis B virus core and e antigens elicit different Th cell subsets: antigen structure can affect Th cell phenotype J. Virol. 71 1997 2192 2201
15. K.W. Moore, A. O'Garra, R. de Waal Malefyt, P. Vieira, and T.R. Mosmann Interleukin-10 Annu. Rev. Immunol. 11 1993 165 190
16. T.R. Mosmann, and S. Sad The expanding universe of T-cell subsets: Th1, Th2 and more Immunol. Today 17 1996 138 146
17. A. O'Garra Cytokines induce the development of functionally heterogeneous T helper cell subsets Immunity 8 1998 275 283
18. H. Okamura, S. Kashiwamura, H. Tsutsui, T. Yoshimoto, and K. Nakanishi Regulation of interferon-γ production by IL-12 and IL-18 Curr. Opin. Immunol. 10 1998 259 264
19. J.F. Schlaak, G. Tully, H.F. Löhr, G. Gerken, and K.-H. Meyer zum Buschenfelde HBV-specific immune defect in chronic hepatitis B (CHB) is correlated with a dysregulation of pro- and anti-inflammatory cytokines Clin. Exp. Immunol. 115 1999 508 514
20. A. Szkaradkiewicz, A. Jopek, J. Wysocki, M. Grzymisławski, I. Małecka, and A. Woźniak HBcAg-specific cytokine production by CD4 T lymphocytes of children with acute and chronic hepatitis B Virus Res. 97 2003 127 133
21. G. Trinchieri Interleukin-12: a cytokine at the interface of inflammation and immunity Adv. Immunol. 70 1998 83 243
22. G. Trinchieri, and P. Scott Interleukin-12: basic principles and clinical applications Curr. Top. Microbiol. Immunol. 238 1999 57 78
23. M. Yazdanbakhsh, P.G. Kremsner, and R. van Ree Allergy, parasites, and the hygiene hypothesis Science 296 2002 490 494