-
1
-
-
0037146578
-
Finding genes that underlie complex traits
-
Glazier AM, Nadeau JH, Aitman TJ (2002) Finding genes that underlie complex traits. Science 298:2345-2349
-
(2002)
Science
, vol.298
, pp. 2345-2349
-
-
Glazier, A.M.1
Nadeau, J.H.2
Aitman, T.J.3
-
2
-
-
0029741063
-
The future of genetic studies of complex human diseases
-
Risch N, Merikangas K (1996) The future of genetic studies of complex human diseases. Science 273:1516-1517
-
(1996)
Science
, vol.273
, pp. 1516-1517
-
-
Risch, N.1
Merikangas, K.2
-
3
-
-
2642583283
-
Mapping complex disease loci in whole-genome association studies
-
Carlson CS, Eberle MA, Kruglyak L, Nickerson DA (2004) Mapping complex disease loci in whole-genome association studies. Nature 429:446-452
-
(2004)
Nature
, vol.429
, pp. 446-452
-
-
Carlson, C.S.1
Eberle, M.A.2
Kruglyak, L.3
Nickerson, D.A.4
-
4
-
-
0032991552
-
Characterization of single-nucleotide polymorphisms in coding regions of human genes
-
Cargill M, Altshuler D, Ireland J, Sklar P, Ardlie K, Patil N, Shaw N, Lane CR, Lim EP, Kalyanaraman N, Nemesh J, Ziaugra L, Friedland L, Rolfe A, Warrington J, Lipshutz R, Daley GQ, Lander ES (1999) Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nat Genet 22:231-238
-
(1999)
Nat Genet
, vol.22
, pp. 231-238
-
-
Cargill, M.1
Altshuler, D.2
Ireland, J.3
Sklar, P.4
Ardlie, K.5
Patil, N.6
Shaw, N.7
Lane, C.R.8
Lim, E.P.9
Kalyanaraman, N.10
Nemesh, J.11
Ziaugra, L.12
Friedland, L.13
Rolfe, A.14
Warrington, J.15
Lipshutz, R.16
Daley, G.Q.17
Lander, E.S.18
-
5
-
-
0016669094
-
Evolution at two levels in humans and chimpanzees
-
King MC, Wilson AC (1975) Evolution at two levels in humans and chimpanzees. Science 188:107-116
-
(1975)
Science
, vol.188
, pp. 107-116
-
-
King, M.C.1
Wilson, A.C.2
-
6
-
-
0042697343
-
The evolution of transcriptional regulation in eukaryotes
-
Wray GA, Hahn MW, Abouheif E, Bahoff JP, Pizer M, Rockman MV, Romano LA (2003) The evolution of transcriptional regulation in eukaryotes. Mol Biol Evol 20:1377-1419
-
(2003)
Mol Biol Evol
, vol.20
, pp. 1377-1419
-
-
Wray, G.A.1
Hahn, M.W.2
Abouheif, E.3
Bahoff, J.P.4
Pizer, M.5
Rockman, M.V.6
Romano, L.A.7
-
7
-
-
0037456823
-
Genetics of gene expression surveyed in maize, mouse and man
-
Schadt EE, Monks SA, Drake TA, Lusis AJ, Che N, Colinayo V, Ruff TG, Milligan SB, Lamb JR, Cavet G, Linsley PS, Mao M, Stoughton RB, Friend SH (2003) Genetics of gene expression surveyed in maize, mouse and man. Nature 422:297-302
-
(2003)
Nature
, vol.422
, pp. 297-302
-
-
Schadt, E.E.1
Monks, S.A.2
Drake, T.A.3
Lusis, A.J.4
Che, N.5
Colinayo, V.6
Ruff, T.G.7
Milligan, S.B.8
Lamb, J.R.9
Cavet, G.10
Linsley, P.S.11
Mao, M.12
Stoughton, R.B.13
Friend, S.H.14
-
8
-
-
0042856391
-
Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors
-
Yvert G, Brem RB, Whittle J, Akey JM, Foss E, Smith EN, Mackelprang R, Kruglyak L (2003) Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors. Nat Genet 35:57-64
-
(2003)
Nat Genet
, vol.35
, pp. 57-64
-
-
Yvert, G.1
Brem, R.B.2
Whittle, J.3
Akey, J.M.4
Foss, E.5
Smith, E.N.6
Mackelprang, R.7
Kruglyak, L.8
-
9
-
-
0037177625
-
Genetic dissection of transcriptional regulation in budding yeast
-
Brem RB, Yvert G, Clinton R, Kruglyak L (2002) Genetic dissection of transcriptional regulation in budding yeast. Science 296:752-755
-
(2002)
Science
, vol.296
, pp. 752-755
-
-
Brem, R.B.1
Yvert, G.2
Clinton, R.3
Kruglyak, L.4
-
10
-
-
0037572260
-
Population genetic variation in genome-wide gene expression
-
Townsend JP, Cavalieri D, Hartl DL (2003) Population genetic variation in genome-wide gene expression. Mol Biol Evol 20:955-963
-
(2003)
Mol Biol Evol
, vol.20
, pp. 955-963
-
-
Townsend, J.P.1
Cavalieri, D.2
Hartl, D.L.3
-
11
-
-
4944245629
-
Population genetic variation in gene expression is associated with phenotypic variation in Saccharomyces cerevisiae
-
Fay JC, McCullough HL, Sniegowski PD, Eisen MB (2004) Population genetic variation in gene expression is associated with phenotypic variation in Saccharomyces cerevisiae. Genome Biol 5:R26
-
(2004)
Genome Biol
, vol.5
-
-
Fay, J.C.1
McCullough, H.L.2
Sniegowski, P.D.3
Eisen, M.B.4
-
12
-
-
0037313182
-
Evolution of gene expression in the Drosophila melanogaster subgroup
-
Rifkin SA, Kim J, White KP (2003) Evolution of gene expression in the Drosophila melanogaster subgroup. Nat Genet 33:138-144
-
(2003)
Nat Genet
, vol.33
, pp. 138-144
-
-
Rifkin, S.A.1
Kim, J.2
White, K.P.3
-
13
-
-
0036789519
-
Variation in gene expression within and among natural populations
-
Oleksiak MF, Churchill GA, Crawford DL (2002) Variation in gene expression within and among natural populations. Nat Genet 32:261-266
-
(2002)
Nat Genet
, vol.32
, pp. 261-266
-
-
Oleksiak, M.F.1
Churchill, G.A.2
Crawford, D.L.3
-
14
-
-
0037066542
-
Intra- and interspecific variation in primate gene expression patterns
-
Enard W, Khaitovich P, Klose J, Zollner S, Heissig F, Giavalisco P, Nieselt-Struwe K, Muchmore E, Varki A, Ravid R, Doxiadis GM, Bontrop RE, Paabo S (2002) Intra- and interspecific variation in primate gene expression patterns. Science 296:340-343
-
(2002)
Science
, vol.296
, pp. 340-343
-
-
Enard, W.1
Khaitovich, P.2
Klose, J.3
Zollner, S.4
Heissig, F.5
Giavalisco, P.6
Nieselt-Struwe, K.7
Muchmore, E.8
Varki, A.9
Ravid, R.10
Doxiadis, G.M.11
Bontrop, R.E.12
Paabo, S.13
-
15
-
-
0037370311
-
Natural variation in human gene expression assessed in lymphoblastoid cells
-
Cheung VG, Conlin LK, Weber TM, Arcaro M, Jen KY, Morley M, Spielman RS (2003) Natural variation in human gene expression assessed in lymphoblastoid cells. Nat Genet 33:422-425
-
(2003)
Nat Genet
, vol.33
, pp. 422-425
-
-
Cheung, V.G.1
Conlin, L.K.2
Weber, T.M.3
Arcaro, M.4
Jen, K.Y.5
Morley, M.6
Spielman, R.S.7
-
16
-
-
4043128071
-
Genetic analysis of genomewide variation in human gene expression
-
Morley M, Molony CM, Weber TM, Devlin JL, Ewens KG, Spielman RS, Cheung VG (2004) Genetic analysis of genomewide variation in human gene expression. Nature 430:743-747
-
(2004)
Nature
, vol.430
, pp. 743-747
-
-
Morley, M.1
Molony, C.M.2
Weber, T.M.3
Devlin, J.L.4
Ewens, K.G.5
Spielman, R.S.6
Cheung, V.G.7
-
17
-
-
1242271304
-
Allele-specific gene expression uncovered
-
Knight JC (2004) Allele-specific gene expression uncovered. Trends Genet 20:113-116
-
(2004)
Trends Genet
, vol.20
, pp. 113-116
-
-
Knight, J.C.1
-
18
-
-
0037119584
-
Allelic variation in human gene expression
-
Yan H, Yuan W, Velculescu VE, Vogelstein B, Kinzler KW (2002) Allelic variation in human gene expression. Science 297:1143
-
(2002)
Science
, vol.297
, pp. 1143
-
-
Yan, H.1
Yuan, W.2
Velculescu, V.E.3
Vogelstein, B.4
Kinzler, K.W.5
-
19
-
-
10744224159
-
A survey of genetic and epigenetic variation affecting human gene expression
-
Pastinen T, Sladek R, Gurd S, Sammak A, Ge B, Lepage P, Lavergne K, Villeneuve A, Gaudin T, Brandstrom H, Beck A, Verner A, Kingsley J, Harmsen E, Labuda D, Morgan K, Vohl MC, Naumova AK, Sinnett D, Hudson TJ (2004) A survey of genetic and epigenetic variation affecting human gene expression. Physiol Genomics 16:184-193
-
(2004)
Physiol Genomics
, vol.16
, pp. 184-193
-
-
Pastinen, T.1
Sladek, R.2
Gurd, S.3
Sammak, A.4
Ge, B.5
Lepage, P.6
Lavergne, K.7
Villeneuve, A.8
Gaudin, T.9
Brandstrom, H.10
Beck, A.11
Verner, A.12
Kingsley, J.13
Harmsen, E.14
Labuda, D.15
Morgan, K.16
Vohl, M.C.17
Naumova, A.K.18
Sinnett, D.19
Hudson, T.J.20
more..
-
21
-
-
0037623912
-
Cis-acting variation in the expression of a high proportion of genes in human brain
-
Bray NJ, Buckland PR, Owen MJ, O'Donovan MC (2003) Cis-acting variation in the expression of a high proportion of genes in human brain. Hum Genet 113:149-153
-
(2003)
Hum Genet
, vol.113
, pp. 149-153
-
-
Bray, N.J.1
Buckland, P.R.2
Owen, M.J.3
O'Donovan, M.C.4
-
22
-
-
0025029777
-
Reporter genes: Application to the study of mammalian gene transcription
-
Alam J, Cook JL (1990) Reporter genes: application to the study of mammalian gene transcription. Anal Biochem 188:245-254
-
(1990)
Anal Biochem
, vol.188
, pp. 245-254
-
-
Alam, J.1
Cook, J.L.2
-
23
-
-
0036855185
-
Abundant raw material for cis-regulatory evolution in humans
-
Rockman MV, Wray GA (2002) Abundant raw material for cis-regulatory evolution in humans. Mol Biol Evol 19:1991-2004
-
(2002)
Mol Biol Evol
, vol.19
, pp. 1991-2004
-
-
Rockman, M.V.1
Wray, G.A.2
-
24
-
-
0042359360
-
Functional analysis of human promoter polymorphisms
-
Hoogendoorn B, Coleman SL, Guy CA, Smith K, Bowen T, Buckland PR, O'Donovan MC (2003) Functional analysis of human promoter polymorphisms. Hum Mol Genet 12:2249-2254
-
(2003)
Hum Mol Genet
, vol.12
, pp. 2249-2254
-
-
Hoogendoorn, B.1
Coleman, S.L.2
Guy, C.A.3
Smith, K.4
Bowen, T.5
Buckland, P.R.6
O'Donovan, M.C.7
-
25
-
-
2942562374
-
A high proportion of chromosome 21 promoter polymorphisms influence transcriptional activity
-
Buckland PR, Coleman SL, Hoogendoorn B, Guy C, Smith SK, O'Donovan MC (2004) A high proportion of chromosome 21 promoter polymorphisms influence transcriptional activity. Gene Expr 11:233-239
-
(2004)
Gene Expr
, vol.11
, pp. 233-239
-
-
Buckland, P.R.1
Coleman, S.L.2
Hoogendoorn, B.3
Guy, C.4
Smith, S.K.5
O'Donovan, M.C.6
-
26
-
-
3042824629
-
Functional analysis of polymorphisms in the promoter regions of genes on 22q11
-
Hoogendoorn B, Coleman SL, Guy CA, Smith SK, O'Donovan MC, Buckland PR (2004) Functional analysis of polymorphisms in the promoter regions of genes on 22q11. Hum Mutat 24:35-42
-
(2004)
Hum Mutat
, vol.24
, pp. 35-42
-
-
Hoogendoorn, B.1
Coleman, S.L.2
Guy, C.A.3
Smith, S.K.4
O'Donovan, M.C.5
Buckland, P.R.6
-
27
-
-
0036802654
-
SNPs in putative regulatory regions identified by human mouse comparative sequencing and transcription factor binding site data
-
Banerjee P, Bahlo M, Schwartz JR, Loots GG, Houston KA, Dubchak I, Speed TP, Rubin EM (2002) SNPs in putative regulatory regions identified by human mouse comparative sequencing and transcription factor binding site data. Mamm Genome 13:554-557
-
(2002)
Mamm Genome
, vol.13
, pp. 554-557
-
-
Banerjee, P.1
Bahlo, M.2
Schwartz, J.R.3
Loots, G.G.4
Houston, K.A.5
Dubchak, I.6
Speed, T.P.7
Rubin, E.M.8
-
28
-
-
0742306815
-
Computational prediction of transcription-factor binding site locations
-
Bulyk ML (2003) Computational prediction of transcription-factor binding site locations. Genome Biol 5:201
-
(2003)
Genome Biol
, vol.5
, pp. 201
-
-
Bulyk, M.L.1
-
29
-
-
2342507824
-
Quantitative high-throughput analysis of transcription factor binding specificities
-
Linnell J, Mott R, Field S, Kwiatkowski DP, Ragoussis J, Udalova IA (2004) Quantitative high-throughput analysis of transcription factor binding specificities. Nucleic Acids Res 32:e44
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Linnell, J.1
Mott, R.2
Field, S.3
Kwiatkowski, D.P.4
Ragoussis, J.5
Udalova, I.A.6
-
30
-
-
0037648405
-
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
-
Ueda H, Howson JM, Esposito L, Heward J, Snook H, Chamberlain G, Rainbow DB, Hunter KM, Smith AN, Di Genova G, Herr MH, Dahlman I, Payne F, Smyth D, Lowe C, Twells RC, Hewlett S, Healy B, Nutland S, Rance HE, Everett V, Smink LJ, Lam AC, Cordell HJ, Walker NM, Bordin C, Hulme J, Motzo C, Cucca F, Hess JF, Metzker ML, Rogers J, Gregory S, Allahabadia A, Nithiyananthan R, Tuomilehto-Wolf E, Tuomilehto J, Bingley P, Gillespie KM, Undlien DE, Ronningen KS, Guja C, Ionescu-Tirgoviste C, Savage DA, Maxwell AP, Carson DJ, Patterson CC, Franklyn JA, Clayton DG, Peterson LB, Wicker LS, Todd JA, Gough SC (2003) Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 423:506-511
-
(2003)
Nature
, vol.423
, pp. 506-511
-
-
Ueda, H.1
Howson, J.M.2
Esposito, L.3
Heward, J.4
Snook, H.5
Chamberlain, G.6
Rainbow, D.B.7
Hunter, K.M.8
Smith, A.N.9
Di Genova, G.10
Herr, M.H.11
Dahlman, I.12
Payne, F.13
Smyth, D.14
Lowe, C.15
Twells, R.C.16
Hewlett, S.17
Healy, B.18
Nutland, S.19
Rance, H.E.20
Everett, V.21
Smink, L.J.22
Lam, A.C.23
Cordell, H.J.24
Walker, N.M.25
Bordin, C.26
Hulme, J.27
Motzo, C.28
Cucca, F.29
Hess, J.F.30
Metzker, M.L.31
Rogers, J.32
Gregory, S.33
Allahabadia, A.34
Nithiyananthan, R.35
Tuomilehto-Wolf, E.36
Tuomilehto, J.37
Bingley, P.38
Gillespie, K.M.39
Undlien, D.E.40
Ronningen, K.S.41
Guja, C.42
Ionescu-Tirgoviste, C.43
Savage, D.A.44
Maxwell, A.P.45
Carson, D.J.46
Patterson, C.C.47
Franklyn, J.A.48
Clayton, D.G.49
Peterson, L.B.50
Wicker, L.S.51
Todd, J.A.52
Gough, S.C.53
more..
-
31
-
-
0029001881
-
Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy-negative individuals
-
Tournamille C, Colin Y, Cartron JP, Le Van Kim C (1995) Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy-negative individuals. Nat Genet 10:224-228
-
(1995)
Nat Genet
, vol.10
, pp. 224-228
-
-
Tournamille, C.1
Colin, Y.2
Cartron, J.P.3
Le Van Kim, C.4
-
32
-
-
0028881617
-
The minisatellite in the diabetes susceptibility locus IDDM 2 regulates insulin transcription
-
Kennedy GC, German MS, Rutter WJ (1995) The minisatellite in the diabetes susceptibility locus IDDM 2 regulates insulin transcription. Nat Genet 9:293-298
-
(1995)
Nat Genet
, vol.9
, pp. 293-298
-
-
Kennedy, G.C.1
German, M.S.2
Rutter, W.J.3
-
33
-
-
0020080870
-
The highly polymorphic region near the human insulin gene is composed of simple tandemly repeating sequences
-
Bell GI, Selby MJ, Rutter WJ (1982) The highly polymorphic region near the human insulin gene is composed of simple tandemly repeating sequences. Nature 295:31-35
-
(1982)
Nature
, vol.295
, pp. 31-35
-
-
Bell, G.I.1
Selby, M.J.2
Rutter, W.J.3
-
34
-
-
0021343570
-
A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus
-
Bell GI, Horita S, Karam JH (1984) A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus. Diabetes 33:176-183
-
(1984)
Diabetes
, vol.33
, pp. 176-183
-
-
Bell, G.I.1
Horita, S.2
Karam, J.H.3
-
35
-
-
0021847489
-
Type 1 (insulin-dependent) diabetes and a highly variable locus close to the insulin gene on chromosome 11
-
Hitman GA, Tarn AC, Winter RM, Drummond V, Williams LG, Jowett NI, Bottazzo GF, Galton DJ (1985) Type 1 (insulin-dependent) diabetes and a highly variable locus close to the insulin gene on chromosome 11. Diabetologia 28:218-222
-
(1985)
Diabetologia
, vol.28
, pp. 218-222
-
-
Hitman, G.A.1
Tarn, A.C.2
Winter, R.M.3
Drummond, V.4
Williams, L.G.5
Jowett, N.I.6
Bottazzo, G.F.7
Galton, D.J.8
-
36
-
-
0027200763
-
Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR
-
Lucassen AM, Julier C, Beressi JP, Boitard C, Froguel P, Lathrop M, Bell JI (1993) Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR. Nat Genet 4:305-310
-
(1993)
Nat Genet
, vol.4
, pp. 305-310
-
-
Lucassen, A.M.1
Julier, C.2
Beressi, J.P.3
Boitard, C.4
Froguel, P.5
Lathrop, M.6
Bell, J.I.7
-
37
-
-
0028871202
-
Susceptibility to human type 1 diabetes at IDDM 2 is determined by tandem repeat variation at the insulin gene minisatellite locus
-
Bennett ST, Lucassen AM, Gough SC, Powell EE, Undlien DE, Pritchard LE, Merriman ME, Kawaguchi Y, Dronsfield MJ, Pociot F et al (1995) Susceptibility to human type 1 diabetes at IDDM 2 is determined by tandem repeat variation at the insulin gene minisatellite locus. Nat Genet 9:284-292
-
(1995)
Nat Genet
, vol.9
, pp. 284-292
-
-
Bennett, S.T.1
Lucassen, A.M.2
Gough, S.C.3
Powell, E.E.4
Undlien, D.E.5
Pritchard, L.E.6
Merriman, M.E.7
Kawaguchi, Y.8
Dronsfield, M.J.9
Pociot, F.10
-
38
-
-
3042698329
-
Remapping the insulin gene/IDDM 2 locus in type 1 diabetes
-
Barratt BJ, Payne F, Lowe CE, Hermann R, Healy BC, Harold D, Concannon P, Gharani N, McCarthy MI, Olavesen MG, McCormack R, Guja C, Ionescu-Tirgoviste C, Undlien DE, Ronningen KS, Gillespie KM, Tuomilehto-Wolf E, Tuomilehto J, Bennett ST, Clayton DG, Cordell HJ, Todd JA (2004) Remapping the insulin gene/IDDM 2 locus in type 1 diabetes. Diabetes 53:1884-1889
-
(2004)
Diabetes
, vol.53
, pp. 1884-1889
-
-
Barratt, B.J.1
Payne, F.2
Lowe, C.E.3
Hermann, R.4
Healy, B.C.5
Harold, D.6
Concannon, P.7
Gharani, N.8
McCarthy, M.I.9
Olavesen, M.G.10
McCormack, R.11
Guja, C.12
Ionescu-Tirgoviste, C.13
Undlien, D.E.14
Ronningen, K.S.15
Gillespie, K.M.16
Tuomilehto-Wolf, E.17
Tuomilehto, J.18
Bennett, S.T.19
Clayton, D.G.20
Cordell, H.J.21
Todd, J.A.22
more..
-
39
-
-
0028151268
-
The paternally inherited insulin gene B allele (1,428 FokI site) confers protection from insulin-dependent diabetes in families
-
Pugliese A, Awdeh ZL, Alper CA, Jackson RA, Eisenbarth GS (1994) The paternally inherited insulin gene B allele (1,428 FokI site) confers protection from insulin-dependent diabetes in families. J Autoimmunol 7:687-694
-
(1994)
J Autoimmunol
, vol.7
, pp. 687-694
-
-
Pugliese, A.1
Awdeh, Z.L.2
Alper, C.A.3
Jackson, R.A.4
Eisenbarth, G.S.5
-
40
-
-
0001017310
-
IDDM 2-VNTR-encoded susceptibility to type 1 diabetes: Dominant protection and parental transmission of alleles of the insulin gene-linked minisatellite locus
-
Bennett ST, Wilson AJ, Cucca F, Nerup J, Pociot F, McKinney PA, Barnett AH, Bain SC, Todd JA (1996) IDDM 2-VNTR-encoded susceptibility to type 1 diabetes: dominant protection and parental transmission of alleles of the insulin gene-linked minisatellite locus. J Autoimmunol 9:415-421
-
(1996)
J Autoimmunol
, vol.9
, pp. 415-421
-
-
Bennett, S.T.1
Wilson, A.J.2
Cucca, F.3
Nerup, J.4
Pociot, F.5
McKinney, P.A.6
Barnett, A.H.7
Bain, S.C.8
Todd, J.A.9
-
41
-
-
0242524453
-
The inherited basis of diabetes mellitus: Implications for the genetic analysis of complex traits
-
Florez JC, Hirschhorn J, Altshuler D (2003) The inherited basis of diabetes mellitus: implications for the genetic analysis of complex traits. Annu Rev Genomics Hum Genet 4:257-291
-
(2003)
Annu Rev Genomics Hum Genet
, vol.4
, pp. 257-291
-
-
Florez, J.C.1
Hirschhorn, J.2
Altshuler, D.3
-
42
-
-
0030175721
-
Imprinted and genotype-specific expression of genes at the IDDM 2 locus in pancreas and leucocytes
-
Vafiadis P, Bennett ST, Colle E, Grabs R, Goodyer CG, Polychronakos C (1996) Imprinted and genotype-specific expression of genes at the IDDM 2 locus in pancreas and leucocytes. J Autoimmunol 9:397-403
-
(1996)
J Autoimmunol
, vol.9
, pp. 397-403
-
-
Vafiadis, P.1
Bennett, S.T.2
Colle, E.3
Grabs, R.4
Goodyer, C.G.5
Polychronakos, C.6
-
43
-
-
0026568387
-
Central obesity and hyperinsulinaemia in women are associated with polymorphism in the 5′ flanking region of the human insulin gene
-
Weaver JU, Kopelman PG, Hitman GA (1992) Central obesity and hyperinsulinaemia in women are associated with polymorphism in the 5′ flanking region of the human insulin gene. Eur J Clin Invest 22:265-270
-
(1992)
Eur J Clin Invest
, vol.22
, pp. 265-270
-
-
Weaver, J.U.1
Kopelman, P.G.2
Hitman, G.A.3
-
44
-
-
0024232010
-
Polymorphism at the 5′ end flanking region of the insulin gene is associated with reduced insulin secretion in healthy individuals
-
Cocozza S, Riccardi G, Monticelli A, Capaldo B, Genovese S, Krogh V, Celentano E, Farinaro E, Varrone S, Avvedimento VE (1988) Polymorphism at the 5′ end flanking region of the insulin gene is associated with reduced insulin secretion in healthy individuals. Eur J Clin Invest 18:582-586
-
(1988)
Eur J Clin Invest
, vol.18
, pp. 582-586
-
-
Cocozza, S.1
Riccardi, G.2
Monticelli, A.3
Capaldo, B.4
Genovese, S.5
Krogh, V.6
Celentano, E.7
Farinaro, E.8
Varrone, S.9
Avvedimento, V.E.10
-
45
-
-
0021943651
-
Islet beta-cell function and polymorphism in the 5′-flanking region of the human insulin gene
-
Permutt MA, Rotwein P, Andreone T, Ward WK, Porte D Jr (1985) Islet beta-cell function and polymorphism in the 5′-flanking region of the human insulin gene. Diabetes 34:311-314
-
(1985)
Diabetes
, vol.34
, pp. 311-314
-
-
Permutt, M.A.1
Rotwein, P.2
Andreone, T.3
Ward, W.K.4
Porte Jr., D.5
-
46
-
-
0020027343
-
DNA insertion sequences near the insulin gene affect glucose regulation
-
Owerbach D, Poulsen S, Billesbolle P, Nerup J (1982) DNA insertion sequences near the insulin gene affect glucose regulation. Lancet 1:880-883
-
(1982)
Lancet
, vol.1
, pp. 880-883
-
-
Owerbach, D.1
Poulsen, S.2
Billesbolle, P.3
Nerup, J.4
-
47
-
-
0028964371
-
Regulation of insulin gene expression by the IDDM associated, insulin locus haplotype
-
Lucassen AM, Screaton GR, Julier C, Elliott TJ, Lathrop M, Bell JI (1995) Regulation of insulin gene expression by the IDDM associated, insulin locus haplotype. Hum Mol Genet 4:501-506
-
(1995)
Hum Mol Genet
, vol.4
, pp. 501-506
-
-
Lucassen, A.M.1
Screaton, G.R.2
Julier, C.3
Elliott, T.J.4
Lathrop, M.5
Bell, J.I.6
-
48
-
-
0030573027
-
Structure-function correlations of the insulin-linked polymorphic region
-
Catasti P, Chen X, Moyzis RK, Bradbury EM, Gupta G (1996) Structure-function correlations of the insulin-linked polymorphic region. J Mol Biol 264:534-545
-
(1996)
J Mol Biol
, vol.264
, pp. 534-545
-
-
Catasti, P.1
Chen, X.2
Moyzis, R.K.3
Bradbury, E.M.4
Gupta, G.5
-
49
-
-
0033740378
-
Unusual DNA structure of the diabetes susceptibility locus IDDM 2 and its effect on transcription by the insulin promoter factor Pur-1/MAZ
-
Lew A, Rutter WJ, Kennedy GC (2000) Unusual DNA structure of the diabetes susceptibility locus IDDM 2 and its effect on transcription by the insulin promoter factor Pur-1/MAZ. Proc Natl Acad Sci U S A 97:12508-12512
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 12508-12512
-
-
Lew, A.1
Rutter, W.J.2
Kennedy, G.C.3
-
50
-
-
18244421874
-
The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM 2 susceptibility locus for type 1 diabetes
-
Pugliese A, Zeller M, Fernandez A Jr, Zalcberg LJ, Bartlett RJ, Ricordi C, Pietropaolo M, Eisenbarth GS, Bennett ST, Patel DD (1997) The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM 2 susceptibility locus for type 1 diabetes. Nat Genet 15:293-297
-
(1997)
Nat Genet
, vol.15
, pp. 293-297
-
-
Pugliese, A.1
Zeller, M.2
Fernandez Jr., A.3
Zalcberg, L.J.4
Bartlett, R.J.5
Ricordi, C.6
Pietropaolo, M.7
Eisenbarth, G.S.8
Bennett, S.T.9
Patel, D.D.10
-
51
-
-
0031018819
-
Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM 2 locus
-
Vafiadis P, Bennett ST, Todd JA, Nadeau J, Grabs R, Goodyer CG, Wickramasinghe S, Colle E, Polychronakos C (1997) Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM 2 locus. Nat Genet 15:289-292
-
(1997)
Nat Genet
, vol.15
, pp. 289-292
-
-
Vafiadis, P.1
Bennett, S.T.2
Todd, J.A.3
Nadeau, J.4
Grabs, R.5
Goodyer, C.G.6
Wickramasinghe, S.7
Colle, E.8
Polychronakos, C.9
-
52
-
-
0032486384
-
The INS 5′ variable number of tandem repeats is associated with IGF2 expression in humans
-
Paquette J, Giannoukakis N, Polychronakos C, Vafiadis P, Deal C (1998) The INS 5′ variable number of tandem repeats is associated with IGF2 expression in humans. J Biol Chem 273:14158-14164
-
(1998)
J Biol Chem
, vol.273
, pp. 14158-14164
-
-
Paquette, J.1
Giannoukakis, N.2
Polychronakos, C.3
Vafiadis, P.4
Deal, C.5
-
53
-
-
0031944926
-
A functional analysis of the role of IGF2 in IDDM 2-encoded susceptibility to type 1 diabetes
-
Vafiadis P, Grabs R, Goodyer CG, Colle E, Polychronakos C (1998) A functional analysis of the role of IGF2 in IDDM 2-encoded susceptibility to type 1 diabetes. Diabetes 47:831-836
-
(1998)
Diabetes
, vol.47
, pp. 831-836
-
-
Vafiadis, P.1
Grabs, R.2
Goodyer, C.G.3
Colle, E.4
Polychronakos, C.5
-
54
-
-
0035653671
-
Genetics of susceptibility to human infectious disease
-
Cooke GS, Hill AV (2001 ) Genetics of susceptibility to human infectious disease. Nat Rev Genet 2:967-977
-
(2001)
Nat Rev Genet
, vol.2
, pp. 967-977
-
-
Cooke, G.S.1
Hill, A.V.2
-
56
-
-
16044373004
-
Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
-
Samson M, Libert F, Doranz BJ, Rucker J, Liesnard C, Farber CM, Saragosti S, Lapoumeroulie C, Cognaux J, Forceille C, Muyldermans G, Verhofstede C, Burtonboy G, Georges M, Imai T, Rana S, Yi Y, Smyth RJ, Collman RG, Doms RW, Vassart G, Parmentier M (1996) Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 382:722-725
-
(1996)
Nature
, vol.382
, pp. 722-725
-
-
Samson, M.1
Libert, F.2
Doranz, B.J.3
Rucker, J.4
Liesnard, C.5
Farber, C.M.6
Saragosti, S.7
Lapoumeroulie, C.8
Cognaux, J.9
Forceille, C.10
Muyldermans, G.11
Verhofstede, C.12
Burtonboy, G.13
Georges, M.14
Imai, T.15
Rana, S.16
Yi, Y.17
Smyth, R.J.18
Collman, R.G.19
Doms, R.W.20
Vassart, G.21
Parmentier, M.22
more..
-
57
-
-
16044367526
-
The role of a mutant CCR5 allele in HIV-1 transmission and disease progression
-
Huang Y, Paxton WA, Wolinsky SM, Neumann AU, Zhang L, He T, Kang S, Ceradini D, Jin Z, Yazdanbakhsh K, Kunstman K, Erickson D, Dragon E, Landau NR, Phair J, Ho DD, Koup RA (1996) The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nat Med 2:1240-1243
-
(1996)
Nat Med
, vol.2
, pp. 1240-1243
-
-
Huang, Y.1
Paxton, W.A.2
Wolinsky, S.M.3
Neumann, A.U.4
Zhang, L.5
He, T.6
Kang, S.7
Ceradini, D.8
Jin, Z.9
Yazdanbakhsh, K.10
Kunstman, K.11
Erickson, D.12
Dragon, E.13
Landau, N.R.14
Phair, J.15
Ho, D.D.16
Koup, R.A.17
-
58
-
-
2142770398
-
The impact of human allelic variation on HIV-1 disease
-
Anastassopoulou CG, Kostrikis LG (2003) The impact of human allelic variation on HIV-1 disease. Curr HIV Res 1:185-203
-
(2003)
Curr HIV Res
, vol.1
, pp. 185-203
-
-
Anastassopoulou, C.G.1
Kostrikis, L.G.2
-
59
-
-
0032484088
-
Genetic acceleration of AIDS progression by a promoter variant of CCR5
-
Martin MP, Dean M, Smith MW, Winkler C, Gerrard B, Michael NL, Lee B, Doms RW, Margolick J, Buchbinder S, Goedert JJ, O'Brien TR, Hilgartner MW, Vlahov D, O'Brien SJ, Carrington M (1998) Genetic acceleration of AIDS progression by a promoter variant of CCR5. Science 282:1907-1911
-
(1998)
Science
, vol.282
, pp. 1907-1911
-
-
Martin, M.P.1
Dean, M.2
Smith, M.W.3
Winkler, C.4
Gerrard, B.5
Michael, N.L.6
Lee, B.7
Doms, R.W.8
Margolick, J.9
Buchbinder, S.10
Goedert, J.J.11
O'Brien, T.R.12
Hilgartner, M.W.13
Vlahov, D.14
O'Brien, S.J.15
Carrington, M.16
-
60
-
-
0032511573
-
CCR5 promoter polymorphism and HIV-1 disease progression. Multicenter AIDS Cohort Study (MACS)
-
McDermott DH, Zimmerman PA, Guignard F, Kleeberger CA, Leitman SF, Murphy PM (1998) CCR5 promoter polymorphism and HIV-1 disease progression. Multicenter AIDS Cohort Study (MACS). Lancet 352:866-870
-
(1998)
Lancet
, vol.352
, pp. 866-870
-
-
McDermott, D.H.1
Zimmerman, P.A.2
Guignard, F.3
Kleeberger, C.A.4
Leitman, S.F.5
Murphy, P.M.6
-
61
-
-
0031874343
-
Genealogy of the CCR5 locus and chemokine system gene variants associated with altered rates of HIV-1 disease progression
-
Mummidi S, Ahuja SS, Gonzalez E, Anderson SA, Santiago EN, Stephan KT, Craig FE, O'Connell P, Tryon V, Clark RA, Dolan MJ, Ahuja SK (1998) Genealogy of the CCR5 locus and chemokine system gene variants associated with altered rates of HIV-1 disease progression. Nat Med 4:786-793
-
(1998)
Nat Med
, vol.4
, pp. 786-793
-
-
Mummidi, S.1
Ahuja, S.S.2
Gonzalez, E.3
Anderson, S.A.4
Santiago, E.N.5
Stephan, K.T.6
Craig, F.E.7
O'Connell, P.8
Tryon, V.9
Clark, R.A.10
Dolan, M.J.11
Ahuja, S.K.12
-
62
-
-
0003184041
-
CCR5 promoter polymorphisms, CCR5 59029A and CCR5 59353C, are under represented in HIV-1-infected long-term non-progressors
-
The Australian Long-Term Non-Progressor Study Group
-
Clegg AO, Ashton LJ, Biti RA, Badhwar P, Williamson P, Kaldor JM, Stewart GJ (2000) CCR5 promoter polymorphisms, CCR5 59029A and CCR5 59353C, are under represented in HIV-1-infected long-term non-progressors. The Australian Long-Term Non-Progressor Study Group. AIDS 14:103-108
-
(2000)
AIDS
, vol.14
, pp. 103-108
-
-
Clegg, A.O.1
Ashton, L.J.2
Biti, R.A.3
Badhwar, P.4
Williamson, P.5
Kaldor, J.M.6
Stewart, G.J.7
-
64
-
-
0034705597
-
Evolution of human and non-human primate CC chemokine receptor 5 gene and mRNA. Potential roles for haplotype and mRNA diversity, differential haplotype-specific transcriptional activity, and altered transcription factor binding to polymorphic nucleotides in the pathogenesis of HIV-1 and simian immunodeficiency virus
-
Mummidi S, Bamshad M, Ahuja SS, Gonzalez E, Feuillet PM, Begum K, Galvis MC, Kostecki V, Valente AJ, Murthy KK, Haro L, Dolan MJ, Allan JS, Ahuja SK (2000) Evolution of human and non-human primate CC chemokine receptor 5 gene and mRNA. Potential roles for haplotype and mRNA diversity, differential haplotype-specific transcriptional activity, and altered transcription factor binding to polymorphic nucleotides in the pathogenesis of HIV-1 and simian immunodeficiency virus. J Biol Chem 275:18946-18961
-
(2000)
J Biol Chem
, vol.275
, pp. 18946-18961
-
-
Mummidi, S.1
Bamshad, M.2
Ahuja, S.S.3
Gonzalez, E.4
Feuillet, P.M.5
Begum, K.6
Galvis, M.C.7
Kostecki, V.8
Valente, A.J.9
Murthy, K.K.10
Haro, L.11
Dolan, M.J.12
Allan, J.S.13
Ahuja, S.K.14
-
65
-
-
0141565366
-
CCR5 promoter polymorphism determines macrophage CCR5 density and magnitude of HIV-1 propagation in vitro
-
Salkowitz JR, Bruse SE, Meyerson H, Valdez H, Mosier DE, Harding CV, Zimmerman PA, Lederman MM (2003) CCR5 promoter polymorphism determines macrophage CCR5 density and magnitude of HIV-1 propagation in vitro. Clin Immunol 108:234-240
-
(2003)
Clin Immunol
, vol.108
, pp. 234-240
-
-
Salkowitz, J.R.1
Bruse, S.E.2
Meyerson, H.3
Valdez, H.4
Mosier, D.E.5
Harding, C.V.6
Zimmerman, P.A.7
Lederman, M.M.8
-
66
-
-
0038153897
-
R5 HIV productively infects Langerhans cells, and infection levels are regulated by compound CCR5 polymorphisms
-
Kawamura T, Gulden FO, Sugaya M, McNamara DT, Borris DL, Lederman MM, Orenstein JM, Zimmerman PA, Blauvelt A (2003) R5 HIV productively infects Langerhans cells, and infection levels are regulated by compound CCR5 polymorphisms. Proc Natl Acad Sci U S A 100:8401-8406
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 8401-8406
-
-
Kawamura, T.1
Gulden, F.O.2
Sugaya, M.3
McNamara, D.T.4
Borris, D.L.5
Lederman, M.M.6
Orenstein, J.M.7
Zimmerman, P.A.8
Blauvelt, A.9
-
67
-
-
0001676483
-
CCR5 promoter alleles and specific DNA binding factors
-
Bream JH, Young HA, Rice N, Martin MP, Smith MW, Carrington M, O'Brien SJ (1999) CCR5 promoter alleles and specific DNA binding factors. Science 284:223
-
(1999)
Science
, vol.284
, pp. 223
-
-
Bream, J.H.1
Young, H.A.2
Rice, N.3
Martin, M.P.4
Smith, M.W.5
Carrington, M.6
O'Brien, S.J.7
-
68
-
-
0030745793
-
Genetic linkage of mild malaria to the major histocompatibility complex in Gambian children: Study of affected sibling pairs
-
Jepson A, Sisay-Joof F, Banya W, Hassan-King M, Frodsham A, Bennett S, Hill AVS, Whittle H (1997) Genetic linkage of mild malaria to the major histocompatibility complex in Gambian children: study of affected sibling pairs. BMJ 315:96-97
-
(1997)
BMJ
, vol.315
, pp. 96-97
-
-
Jepson, A.1
Sisay-Joof, F.2
Banya, W.3
Hassan-King, M.4
Frodsham, A.5
Bennett, S.6
Hill, A.V.S.7
Whittle, H.8
-
69
-
-
0037440668
-
Linkage of mild malaria to the major histocompatibility complex in families living in Burkina Faso
-
Flori L, Sawadogo S, Esnault C, Delahaye NF, Fumoux F, Rihet P (2003) Linkage of mild malaria to the major histocompatibility complex in families living in Burkina Faso. Hum Mol Genet 12:375-378
-
(2003)
Hum Mol Genet
, vol.12
, pp. 375-378
-
-
Flori, L.1
Sawadogo, S.2
Esnault, C.3
Delahaye, N.F.4
Fumoux, F.5
Rihet, P.6
-
70
-
-
0028169333
-
Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria
-
McGuire W, Hill AVS, Allsopp CEM, Greenwood BM, Kwiatkowski D (1994) Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria. Nature 371:508-511
-
(1994)
Nature
, vol.371
, pp. 508-511
-
-
McGuire, W.1
Hill, A.V.S.2
Allsopp, C.E.M.3
Greenwood, B.M.4
Kwiatkowski, D.5
-
71
-
-
0032896154
-
TNFalpha*2 marks high risk of severe disease during Plasmodium falciparum malaria and other infections in Sri Lankans
-
Wattavidanage J, Carter R, Perera KL, Munasingha A, Bandara S, McGuinness D, Wickramasinghe AR, Alles HK, Mendis KN, Premawansa S (1999) TNFalpha*2 marks high risk of severe disease during Plasmodium falciparum malaria and other infections in Sri Lankans. Clin Exp Immunol 115:350-355
-
(1999)
Clin Exp Immunol
, vol.115
, pp. 350-355
-
-
Wattavidanage, J.1
Carter, R.2
Perera, K.L.3
Munasingha, A.4
Bandara, S.5
McGuinness, D.6
Wickramasinghe, A.R.7
Alles, H.K.8
Mendis, K.N.9
Premawansa, S.10
-
72
-
-
0038823966
-
Genetic markers for the efficacy of tumour necrosis factor blocking therapy in rheumatoid arthritis
-
Padyukov L, Lampa J, Heimburger M, Ernestam S, Cederholm T, Lundkvist I, Andersson P, Hermansson Y, Harju A, Klareskog L, Bratt J (2003) Genetic markers for the efficacy of tumour necrosis factor blocking therapy in rheumatoid arthritis. Ann Rheum Dis 62:526-529
-
(2003)
Ann Rheum Dis
, vol.62
, pp. 526-529
-
-
Padyukov, L.1
Lampa, J.2
Heimburger, M.3
Ernestam, S.4
Cederholm, T.5
Lundkvist, I.6
Andersson, P.7
Hermansson, Y.8
Harju, A.9
Klareskog, L.10
Bratt, J.11
-
73
-
-
0038681582
-
Polymorphism at position -308 of the tumor necrosis factor alpha gene influences outcome of infliximab therapy in rheumatoid arthritis
-
Mugnier B, Balandraud N, Darque A, Roudier C, Roudier J, Reviron D (2003) Polymorphism at position -308 of the tumor necrosis factor alpha gene influences outcome of infliximab therapy in rheumatoid arthritis. Arthritis Rheum 48:1849-1852
-
(2003)
Arthritis Rheum
, vol.48
, pp. 1849-1852
-
-
Mugnier, B.1
Balandraud, N.2
Darque, A.3
Roudier, C.4
Roudier, J.5
Reviron, D.6
-
74
-
-
0033368180
-
Polymorphism of the human TNF-alpha promoter-random variation or functional diversity?
-
Allen RD (1999) Polymorphism of the human TNF-alpha promoter-random variation or functional diversity? Mol Immunol 36:1017-1027
-
(1999)
Mol Immunol
, vol.36
, pp. 1017-1027
-
-
Allen, R.D.1
-
76
-
-
0033934788
-
Effects of stimulus and cell type on the expression of the -308 tumour necrosis factor promoter polymorphism
-
Kroeger KM, Steer JH, Joyce DA, Abraham LJ (2000) Effects of stimulus and cell type on the expression of the -308 tumour necrosis factor promoter polymorphism. Cytokine 12:110-119
-
(2000)
Cytokine
, vol.12
, pp. 110-119
-
-
Kroeger, K.M.1
Steer, J.H.2
Joyce, D.A.3
Abraham, L.J.4
-
77
-
-
0030862033
-
The -308 tumor necrosis factor-alpha promoter polymorphism effects transcription
-
Kroeger KM, Carville KS, Abraham LJ (1997) The -308 tumor necrosis factor-alpha promoter polymorphism effects transcription. Mol Immunol 34:391-399
-
(1997)
Mol Immunol
, vol.34
, pp. 391-399
-
-
Kroeger, K.M.1
Carville, K.S.2
Abraham, L.J.3
-
78
-
-
0030954180
-
Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation
-
Wilson AG, Symons JA, McDowell TL, McDevitt HO, Duff GW (1997) Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci USA 94:3195-3199
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3195-3199
-
-
Wilson, A.G.1
Symons, J.A.2
McDowell, T.L.3
McDevitt, H.O.4
Duff, G.W.5
-
79
-
-
0032993434
-
A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria
-
Knight JC, Udalova I, Hill AV, Greenwood BM, Peshu N, Marsh K, Kwiatkowski D (1999) A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria. Nat Genet 22:145-150
-
(1999)
Nat Genet
, vol.22
, pp. 145-150
-
-
Knight, J.C.1
Udalova, I.2
Hill, A.V.3
Greenwood, B.M.4
Peshu, N.5
Marsh, K.6
Kwiatkowski, D.7
-
80
-
-
0037381011
-
In vivo characterization of regulatory polymorphisms by allele-specific quantification of RNA polymerase loading
-
Knight JC, Keating BJ, Rockett KA, Kwiatkowski DP (2003) In vivo characterization of regulatory polymorphisms by allele-specific quantification of RNA polymerase loading. Nat Genet 33:469-475
-
(2003)
Nat Genet
, vol.33
, pp. 469-475
-
-
Knight, J.C.1
Keating, B.J.2
Rockett, K.A.3
Kwiatkowski, D.P.4
-
81
-
-
18744407845
-
Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction
-
Ozaki K, Ohnishi Y, Iida A, Sekine A, Yamada R, Tsunoda T, Sato H, Hori M, Nakamura Y, Tanaka T (2002) Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction. Nat Genet 32:650-654
-
(2002)
Nat Genet
, vol.32
, pp. 650-654
-
-
Ozaki, K.1
Ohnishi, Y.2
Iida, A.3
Sekine, A.4
Yamada, R.5
Tsunoda, T.6
Sato, H.7
Hori, M.8
Nakamura, Y.9
Tanaka, T.10
-
82
-
-
0037231702
-
The effect of HLA-DR on susceptibility to rheumatoid arthritis is influenced by the associated lymphotoxin alpha-tumor necrosis factor haplotype
-
Newton J, Brown MA, Milicic A, Ackerman H, Darke C, Wilson JN, Wordsworth BP, Kwiatkowski D (2003) The effect of HLA-DR on susceptibility to rheumatoid arthritis is influenced by the associated lymphotoxin alpha-tumor necrosis factor haplotype. Arthritis Rheum 48:90-96
-
(2003)
Arthritis Rheum
, vol.48
, pp. 90-96
-
-
Newton, J.1
Brown, M.A.2
Milicic, A.3
Ackerman, H.4
Darke, C.5
Wilson, J.N.6
Wordsworth, B.P.7
Kwiatkowski, D.8
-
83
-
-
1842483836
-
Allele-specific repression of lymphotoxin-alpha by activated B cell factor-1
-
Knight JC, Keating BJ, Kwiatkowski DP (2004) Allele-specific repression of lymphotoxin-alpha by activated B cell factor-1. Nat Genet 36:394-399
-
(2004)
Nat Genet
, vol.36
, pp. 394-399
-
-
Knight, J.C.1
Keating, B.J.2
Kwiatkowski, D.P.3
-
84
-
-
0032958707
-
Severe malarial anemia and cerebral malaria are associated with different tumor necrosis factor promoter alleles
-
McGuire W, Knight JC, Hill AV, Allsopp CE, Greenwood BM, Kwiatkowski D (1999) Severe malarial anemia and cerebral malaria are associated with different tumor necrosis factor promoter alleles. J Infect Dis 179:287-290
-
(1999)
J Infect Dis
, vol.179
, pp. 287-290
-
-
McGuire, W.1
Knight, J.C.2
Hill, A.V.3
Allsopp, C.E.4
Greenwood, B.M.5
Kwiatkowski, D.6
-
85
-
-
0037318361
-
Human genetic polymorphisms and asymptomatic Plasmodium falciparum malaria in Gabonese schoolchildren
-
Mombo LE, Ntoumi F, Bisseye C, Ossari S, Lu CY, Nagel RL, Krishnamoorthy R (2003) Human genetic polymorphisms and asymptomatic Plasmodium falciparum malaria in Gabonese schoolchildren. Am J Trop Med Hyg 68:186-190
-
(2003)
Am J Trop Med Hyg
, vol.68
, pp. 186-190
-
-
Mombo, L.E.1
Ntoumi, F.2
Bisseye, C.3
Ossari, S.4
Lu, C.Y.5
Nagel, R.L.6
Krishnamoorthy, R.7
-
86
-
-
0028318464
-
Identification and characterization of a novel repressor site in the human tumor necrosis factor alpha gene
-
Fong CL, Siddiqui AH, Mark DF (1994) Identification and characterization of a novel repressor site in the human tumor necrosis factor alpha gene. Nucleic Acids Res 22:1108-1114
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 1108-1114
-
-
Fong, C.L.1
Siddiqui, A.H.2
Mark, D.F.3
-
87
-
-
0036138727
-
Tumor necrosis factor-alpha gene polymorphism in severe and mild-moderate rheumatoid arthritis
-
Fabris M, Di PE, D'Elia A, Damante G, Sinigaglia L, Ferraccioli G (2002) Tumor necrosis factor-alpha gene polymorphism in severe and mild-moderate rheumatoid arthritis. J Rheumatol 29:29-33
-
(2002)
J Rheumatol
, vol.29
, pp. 29-33
-
-
Fabris, M.1
Di, P.E.2
D'Elia, A.3
Damante, G.4
Sinigaglia, L.5
Ferraccioli, G.6
-
88
-
-
0030810790
-
Tumour necrosis factor alpha gene polymorphisms in rheumatoid arthritis: Association with susceptibility to, or severity of, disease?
-
Brinkman BM, Huizinga TW, Kurban SS, van der Velde EA, Schreuder GM, Hazes JM, Breedveld FC, Verweij CL (1997) Tumour necrosis factor alpha gene polymorphisms in rheumatoid arthritis: association with susceptibility to, or severity of, disease? Br J Rheumatol 36:516-521
-
(1997)
Br J Rheumatol
, vol.36
, pp. 516-521
-
-
Brinkman, B.M.1
Huizinga, T.W.2
Kurban, S.S.3
Van Der Velde, E.A.4
Schreuder, G.M.5
Hazes, J.M.6
Breedveld, F.C.7
Verweij, C.L.8
-
89
-
-
0036040213
-
Factor VII Deficiency
-
Perry DJ (2002) Factor VII Deficiency. Br J Haematol 118:689-700
-
(2002)
Br J Haematol
, vol.118
, pp. 689-700
-
-
Perry, D.J.1
-
90
-
-
0031026003
-
Severe factor VII deficiency due to a mutation disrupting a hepatocyte nuclear factor 4 binding site in the factor VII promoter
-
Arbini AA, Pollak ES, Bayleran JK, High KA, Bauer KA (1997) Severe factor VII deficiency due to a mutation disrupting a hepatocyte nuclear factor 4 binding site in the factor VII promoter. Blood 89:176-182
-
(1997)
Blood
, vol.89
, pp. 176-182
-
-
Arbini, A.A.1
Pollak, E.S.2
Bayleran, J.K.3
High, K.A.4
Bauer, K.A.5
-
91
-
-
0030071173
-
Functional characterization of the human factor VII 5′-flanking region
-
Pollak ES, Hung HL, Godin W, Overton GC, High KA (1996) Functional characterization of the human factor VII 5′-flanking region. J Biol Chem 271:1738-1747
-
(1996)
J Biol Chem
, vol.271
, pp. 1738-1747
-
-
Pollak, E.S.1
Hung, H.L.2
Godin, W.3
Overton, G.C.4
High, K.A.5
-
92
-
-
0034672258
-
A new mutation in the HNF4 binding region of the factor VII promoter in a patient with severe factor VII deficiency
-
Carew JA, Pollak ES, Lopaciuk S, Bauer KA (2000) A new mutation in the HNF4 binding region of the factor VII promoter in a patient with severe factor VII deficiency. Blood 96:4370-4372
-
(2000)
Blood
, vol.96
, pp. 4370-4372
-
-
Carew, J.A.1
Pollak, E.S.2
Lopaciuk, S.3
Bauer, K.A.4
-
93
-
-
0032170577
-
Severe factor VII deficiency due to a mutation disrupting an Sp1 binding site in the factor VII promoter
-
Carew JA, Pollak ES, High KA, Bauer KA (1998) Severe factor VII deficiency due to a mutation disrupting an Sp1 binding site in the factor VII promoter. Blood 92:1639-1645
-
(1998)
Blood
, vol.92
, pp. 1639-1645
-
-
Carew, J.A.1
Pollak, E.S.2
High, K.A.3
Bauer, K.A.4
-
94
-
-
0029559772
-
Liver-specific expression of the human factor VII gene
-
Greenberg D, Miao CH, Ho WT, Chung DW, Davie EW (1995) Liver-specific expression of the human factor VII gene. Proc Natl Acad Sci USA 92:12347-12351
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 12347-12351
-
-
Greenberg, D.1
Miao, C.H.2
Ho, W.T.3
Chung, D.W.4
Davie, E.W.5
-
95
-
-
0022485106
-
Haemostatic function and ischaemic heart disease: Principal results of the Northwick Park Heart Study
-
Meade TW, Mellows S, Brozovic M, Miller GJ, Chakrabarti RR, North WR, Haines AP, Stirling Y, Imeson JD, Thompson SG (1986) Haemostatic function and ischaemic heart disease: principal results of the Northwick Park Heart Study. Lancet 11:533-537
-
(1986)
Lancet
, vol.11
, pp. 533-537
-
-
Meade, T.W.1
Mellows, S.2
Brozovic, M.3
Miller, G.J.4
Chakrabarti, R.R.5
North, W.R.6
Haines, A.P.7
Stirling, Y.8
Imeson, J.D.9
Thompson, S.G.10
-
96
-
-
9044243754
-
Factor VII gene polymorphisms contribute about one third of the factor VII level variation in plasma
-
Bernardi F, Marchetti G, Pinotti M, Arcieri P, Baroncini C, Papacchini M, Zepponi E, Ursicino N, Chiarotti F, Mariani G (1996) Factor VII gene polymorphisms contribute about one third of the factor VII level variation in plasma. Arterioscler Thromb Vasc Biol 16:72-76
-
(1996)
Arterioscler Thromb Vasc Biol
, vol.16
, pp. 72-76
-
-
Bernardi, F.1
Marchetti, G.2
Pinotti, M.3
Arcieri, P.4
Baroncini, C.5
Papacchini, M.6
Zepponi, E.7
Ursicino, N.8
Chiarotti, F.9
Mariani, G.10
-
97
-
-
0025860324
-
A common genetic polymorphism associated with lower coagulation factor VII levels in healthy individuals
-
Green F, Kelleher C, Wilkes H, Temple A, Meade T, Humphries S (1991) A common genetic polymorphism associated with lower coagulation factor VII levels in healthy individuals. Arterioscler Thromb 11:540-546
-
(1991)
Arterioscler Thromb
, vol.11
, pp. 540-546
-
-
Green, F.1
Kelleher, C.2
Wilkes, H.3
Temple, A.4
Meade, T.5
Humphries, S.6
-
98
-
-
0032495540
-
Polymorphisms in the coagulation factor VII gene and the risk of myocardial infarction
-
Iacoviello L, Di Castelnuovo A, De Knijff P, D'Orazio A, Amore C, Arboretti R, Kluft C, Benedetta Donati M (1998) Polymorphisms in the coagulation factor VII gene and the risk of myocardial infarction. N Engl J Med 338:79-85
-
(1998)
N Engl J Med
, vol.338
, pp. 79-85
-
-
Iacoviello, L.1
Di Castelnuovo, A.2
De Knijff, P.3
D'Orazio, A.4
Amore, C.5
Arboretti, R.6
Kluft, C.7
Benedetta Donati, M.8
-
99
-
-
0034648734
-
Polymorphisms in the factor VII gene and the risk of myocardial infarction in patients with coronary artery disease
-
Girelli D, Russo C, Ferraresi P, Olivieri O, Pinotti M, Friso S, Manzato F, Mazzucco A, Bernardi F, Corrocher R (2000) Polymorphisms in the factor VII gene and the risk of myocardial infarction in patients with coronary artery disease. N Engl J Med 343:774-780
-
(2000)
N Engl J Med
, vol.343
, pp. 774-780
-
-
Girelli, D.1
Russo, C.2
Ferraresi, P.3
Olivieri, O.4
Pinotti, M.5
Friso, S.6
Manzato, F.7
Mazzucco, A.8
Bernardi, F.9
Corrocher, R.10
-
100
-
-
0031822882
-
A genetic propensity to high factor VII is not associated with the risk of myocardial infarction in men
-
Doggen CJ, Manger Cats V, Bertina RM, Reitsma PH, Vandenbroucke JP, Rosendaal FR (1998) A genetic propensity to high factor VII is not associated with the risk of myocardial infarction in men. Thromb Haemost 80:281-285
-
(1998)
Thromb Haemost
, vol.80
, pp. 281-285
-
-
Doggen, C.J.1
Manger Cats, V.2
Bertina, R.M.3
Reitsma, P.H.4
Vandenbroucke, J.P.5
Rosendaal, F.R.6
-
101
-
-
0034808089
-
Lack of association between polymorphisms of the coagulation factor VII and myocardial infarction in middle-aged Spanish men
-
Batalla A, Alvarez R, Reguero JR, Gonzalez P, Alvarez V, Cubero GI, Cortina A, Coto E (2001) Lack of association between polymorphisms of the coagulation factor VII and myocardial infarction in middle-aged Spanish men. Int J Cardiol 80:209-212
-
(2001)
Int J Cardiol
, vol.80
, pp. 209-212
-
-
Batalla, A.1
Alvarez, R.2
Reguero, J.R.3
Gonzalez, P.4
Alvarez, V.5
Cubero, G.I.6
Cortina, A.7
Coto, E.8
-
102
-
-
3042784849
-
A functional haplotype in the 5′ flanking region of the factor VII gene is associated with an increased risk of coronary heart disease
-
Carew JA, Basso F, Miller GJ, Hawe E, Jackson AA, Humphries SE, Bauer KA (2003) A functional haplotype in the 5′ flanking region of the factor VII gene is associated with an increased risk of coronary heart disease. J Thromb Haemost 1:2179-2185
-
(2003)
J Thromb Haemost
, vol.1
, pp. 2179-2185
-
-
Carew, J.A.1
Basso, F.2
Miller, G.J.3
Hawe, E.4
Jackson, A.A.5
Humphries, S.E.6
Bauer, K.A.7
-
103
-
-
0033997379
-
The decanucleotide insertion/deletion polymorphism in the promoter region of the coagulation factor VII gene and the risk of familial myocardial infarction
-
Di Castelnuovo A, D'Orazio A, Amore C, Falanga A, Donati MB, Iacoviello L (2000) The decanucleotide insertion/deletion polymorphism in the promoter region of the coagulation factor VII gene and the risk of familial myocardial infarction. Thromb Res 98:9-17
-
(2000)
Thromb Res
, vol.98
, pp. 9-17
-
-
Di Castelnuovo, A.1
D'Orazio, A.2
Amore, C.3
Falanga, A.4
Donati, M.B.5
Iacoviello, L.6
-
104
-
-
0029919365
-
Low plasma levels of factor VIIc and antigen are more strongly associated with the 10 base pair promoter (-323) insertion than the glutamine 353 variant
-
Humphries S, Temple A, Lane A, Green F, Cooper J, Miller G (1996) Low plasma levels of factor VIIc and antigen are more strongly associated with the 10 base pair promoter (-323) insertion than the glutamine 353 variant. Thromb Haemost 75:567-572
-
(1996)
Thromb Haemost
, vol.75
, pp. 567-572
-
-
Humphries, S.1
Temple, A.2
Lane, A.3
Green, F.4
Cooper, J.5
Miller, G.6
-
105
-
-
0031283266
-
The Arg353Gln polymorphism reduces the level of coagulation factor VII. In vivo and in vitro studies
-
Hunault M, Arbini AA, Lopaciuk S, Carew JA, Bauer KA (1997) The Arg353Gln polymorphism reduces the level of coagulation factor VII. In vivo and in vitro studies. Arterioscler Thromb Vasc Biol 17:2825-2829
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
, pp. 2825-2829
-
-
Hunault, M.1
Arbini, A.A.2
Lopaciuk, S.3
Carew, J.A.4
Bauer, K.A.5
-
106
-
-
0036845560
-
Polymorphic changes in the 5′ flanking region of factor VII have a combined effect on promoter strength
-
Kudaravalli R, Tidd T, Pinotti M, Ratti A, Santacroce R, Margaglione M, Dallapiccola B, Bernardi F, Fortina P, Devoto M, Pollak ES (2002) Polymorphic changes in the 5′ flanking region of factor VII have a combined effect on promoter strength. Thromb Haemost 88:763-767
-
(2002)
Thromb Haemost
, vol.88
, pp. 763-767
-
-
Kudaravalli, R.1
Tidd, T.2
Pinotti, M.3
Ratti, A.4
Santacroce, R.5
Margaglione, M.6
Dallapiccola, B.7
Bernardi, F.8
Fortina, P.9
Devoto, M.10
Pollak, E.S.11
-
107
-
-
0006369656
-
Two common functional polymorphisms in the promoter region of the coagulation factor VII gene determining plasma factor VII activity and mass concentration
-
Hooft FM van 't, Silveira A, Tornvall P, Iliadou A, Ehrenborg E, Eriksson P, Hamsten A (1999) Two common functional polymorphisms in the promoter region of the coagulation factor VII gene determining plasma factor VII activity and mass concentration. Blood 93:3432-3441
-
(1999)
Blood
, vol.93
, pp. 3432-3441
-
-
Van't Hooft, F.M.1
Silveira, A.2
Tornvall, P.3
Iliadou, A.4
Ehrenborg, E.5
Eriksson, P.6
Hamsten, A.7
-
108
-
-
0034210180
-
Modulation of factor VII levels by intron 7 polymorphisms: Population and in vitro studies
-
Pinotti M, Toso R, Girelli D, Bindini D, Ferraresi P, Papa ML, Corrocher R, Marchetti G, Bernardi F (2000) Modulation of factor VII levels by intron 7 polymorphisms: population and in vitro studies. Blood 95:3423-3428
-
(2000)
Blood
, vol.95
, pp. 3423-3428
-
-
Pinotti, M.1
Toso, R.2
Girelli, D.3
Bindini, D.4
Ferraresi, P.5
Papa, M.L.6
Corrocher, R.7
Marchetti, G.8
Bernardi, F.9
-
109
-
-
0017077503
-
The resistance factor to Plasmodium vivax in blacks. The Duffy-blood-group genotype, FyFy
-
Miller LH, Mason SJ, Clyde DF, McGinniss MH (1976) The resistance factor to Plasmodium vivax in blacks. The Duffy-blood-group genotype, FyFy. N Engl J Med 295:302-304
-
(1976)
N Engl J Med
, vol.295
, pp. 302-304
-
-
Miller, L.H.1
Mason, S.J.2
Clyde, D.F.3
McGinniss, M.H.4
-
110
-
-
0027372505
-
A receptor for the malarial parasite Plasmodium vivax: The erythrocyte chemokine receptor
-
Horuk R, Chitnis CE, Darbonne WC, Colby TJ, Rybicki A, Hadley TJ, Miller LH (1993) A receptor for the malarial parasite Plasmodium vivax: the erythrocyte chemokine receptor. Science 261:1182-1184
-
(1993)
Science
, vol.261
, pp. 1182-1184
-
-
Horuk, R.1
Chitnis, C.E.2
Darbonne, W.C.3
Colby, T.J.4
Rybicki, A.5
Hadley, T.J.6
Miller, L.H.7
-
111
-
-
0033911892
-
Detection of the signature of natural selection in humans: Evidence from the Duffy blood group locus
-
Hamblin MT, Di Rienzo A (2000) Detection of the signature of natural selection in humans: evidence from the Duffy blood group locus. Am J Hum Genet 66:1669-1679
-
(2000)
Am J Hum Genet
, vol.66
, pp. 1669-1679
-
-
Hamblin, M.T.1
Di Rienzo, A.2
-
112
-
-
0037041395
-
An extensive network of coupling among gene expression machines
-
Maniatis T, Reed R (2002) An extensive network of coupling among gene expression machines. Nature 416:499-506
-
(2002)
Nature
, vol.416
, pp. 499-506
-
-
Maniatis, T.1
Reed, R.2
-
113
-
-
0037154982
-
A unified theory of gene expression
-
Orphanides G, Reinberg D (2002) A unified theory of gene expression. Cell 108:439-451
-
(2002)
Cell
, vol.108
, pp. 439-451
-
-
Orphanides, G.1
Reinberg, D.2
-
114
-
-
1942467065
-
Genomic variants in exons and introns: Identifying the splicing spoilers
-
Pagani F, Baralle FE (2004) Genomic variants in exons and introns: identifying the splicing spoilers. Nat Rev Genet 5:389-396
-
(2004)
Nat Rev Genet
, vol.5
, pp. 389-396
-
-
Pagani, F.1
Baralle, F.E.2
-
115
-
-
0035968259
-
A CD45 polymorphism associated with multiple sclerosis disrupts an exonic splicing silencer
-
Lynch KW, Weiss A (2001) A CD45 polymorphism associated with multiple sclerosis disrupts an exonic splicing silencer. J Biol Chem 276:24341-24347
-
(2001)
J Biol Chem
, vol.276
, pp. 24341-24347
-
-
Lynch, K.W.1
Weiss, A.2
-
116
-
-
0033662317
-
A point mutation in PT-PRC is associated with the development of multiple sclerosis
-
Jacobsen M, Schweer D, Ziegler A, Gaber R, Schock S, Schwinzer R, Wonigeit K, Lindert RB, Kantarci O, Schaefer-Klein J, Schipper HI, Oertel WH, Heidenreich F, Weinshenker BG, Sommer N, Hemmer B (2000) A point mutation in PT-PRC is associated with the development of multiple sclerosis. Nat Genet 26:495-499
-
(2000)
Nat Genet
, vol.26
, pp. 495-499
-
-
Jacobsen, M.1
Schweer, D.2
Ziegler, A.3
Gaber, R.4
Schock, S.5
Schwinzer, R.6
Wonigeit, K.7
Lindert, R.B.8
Kantarci, O.9
Schaefer-Klein, J.10
Schipper, H.I.11
Oertel, W.H.12
Heidenreich, F.13
Weinshenker, B.G.14
Sommer, N.15
Hemmer, B.16
-
117
-
-
17944365032
-
PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients
-
Barcellos LF, Caillier S, Dragone L, Elder M, Vittinghoff E, Bucher P, Lincoln RR, Pericak-Vance M, Haines JL, Weiss A, Hauser SL, Oksenberg JR (2001) PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients. Nat Genet 29:23-24
-
(2001)
Nat Genet
, vol.29
, pp. 23-24
-
-
Barcellos, L.F.1
Caillier, S.2
Dragone, L.3
Elder, M.4
Vittinghoff, E.5
Bucher, P.6
Lincoln, R.R.7
Pericak-Vance, M.8
Haines, J.L.9
Weiss, A.10
Hauser, S.L.11
Oksenberg, J.R.12
-
118
-
-
0025277415
-
Genetically determined lack of CD45R-T cells in healthy individuals. Evidence for a regulatory polymorphism of CD45R antigen expression
-
Schwinzer R, Wonigeit K (1990) Genetically determined lack of CD45R-T cells in healthy individuals. Evidence for a regulatory polymorphism of CD45R antigen expression. J Exp Med 171:1803-1808
-
(1990)
J Exp Med
, vol.171
, pp. 1803-1808
-
-
Schwinzer, R.1
Wonigeit, K.2
-
119
-
-
0029067113
-
A point mutation in the human CD45 gene associated with defective splicing of exon A
-
Thude H, Hundrieser J, Wonigeit K, Schwinzer R (1995) A point mutation in the human CD45 gene associated with defective splicing of exon A. Eur J Immunol 25:2101-2106
-
(1995)
Eur J Immunol
, vol.25
, pp. 2101-2106
-
-
Thude, H.1
Hundrieser, J.2
Wonigeit, K.3
Schwinzer, R.4
-
120
-
-
0031984481
-
A point mutation within CD45 exon a is the cause of variant CD45RA splicing in humans
-
Zilch CF, Walker AM, Timon M, Goff LK, Wallace DL, Beverley PC (1998) A point mutation within CD45 exon A is the cause of variant CD45RA splicing in humans. Eur J Immunol 28:22-29
-
(1998)
Eur J Immunol
, vol.28
, pp. 22-29
-
-
Zilch, C.F.1
Walker, A.M.2
Timon, M.3
Goff, L.K.4
Wallace, D.L.5
Beverley, P.C.6
-
121
-
-
0036840704
-
Association of the factor XII 46C>T polymorphism with risk of coronary heart disease (CHD) in the WOSCOPS study
-
Zito F, Lowe GD, Rumley A, McMahon AD, Humphries SE (2002) Association of the factor XII 46C>T polymorphism with risk of coronary heart disease (CHD) in the WOSCOPS study. Atherosclerosis 165:153-158
-
(2002)
Atherosclerosis
, vol.165
, pp. 153-158
-
-
Zito, F.1
Lowe, G.D.2
Rumley, A.3
McMahon, A.D.4
Humphries, S.E.5
-
122
-
-
2442465593
-
Association after linkage analysis indicates that homozygosity for the 46C->T polymorphism in the F12 gene is a genetic risk factor for venous thrombosis
-
Tirado I, Manuel Soria J, Mateo J, Oliver A, Carlos Souto J, Santamaria A, Felices R, Borrell M, Fontcuberta J (2004) Association after linkage analysis indicates that homozygosity for the 46C->T polymorphism in the F12 gene is a genetic risk factor for venous thrombosis. Thromb Haemost 91:899-904
-
(2004)
Thromb Haemost
, vol.91
, pp. 899-904
-
-
Tirado, I.1
Manuel Soria, J.2
Mateo, J.3
Oliver, A.4
Carlos Souto, J.5
Santamaria, A.6
Felices, R.7
Borrell, M.8
Fontcuberta, J.9
-
123
-
-
0032521229
-
A common genetic polymorphism (46 C to T substitution) in the 5′-untranslated region of the coagulation factor XII gene is associated with low translation efficiency and decrease in plasma factor XII level
-
Kanaji T, Okamura T, Osaki K, Kuroiwa M, Shimoda K, Hamasaki N, Niho Y (1998) A common genetic polymorphism (46 C to T substitution) in the 5′-untranslated region of the coagulation factor XII gene is associated with low translation efficiency and decrease in plasma factor XII level. Blood 91:2010-2014
-
(1998)
Blood
, vol.91
, pp. 2010-2014
-
-
Kanaji, T.1
Okamura, T.2
Osaki, K.3
Kuroiwa, M.4
Shimoda, K.5
Hamasaki, N.6
Niho, Y.7
-
124
-
-
0033125184
-
FXII (46C->T) polymorphism and in vivo generation of FXII activity-gene frequencies and relationship in patients with coronary artery disease
-
Kohler HP, Futers TS, Grant PJ (1999) FXII (46C->T) polymorphism and in vivo generation of FXII activity-gene frequencies and relationship in patients with coronary artery disease. Thromb Haemost 81:745-747
-
(1999)
Thromb Haemost
, vol.81
, pp. 745-747
-
-
Kohler, H.P.1
Futers, T.S.2
Grant, P.J.3
-
125
-
-
0034711163
-
Epidemiological and genetic associations of activated factor XII concentration with factor VII activity, fibrinopeptide A concentration, and risk of coronary heart disease in men
-
Zito F, Drummond F, Bujac SR, Esnouf MP, Morrissey JH, Humphries SE, Miller GJ (2000) Epidemiological and genetic associations of activated factor XII concentration with factor VII activity, fibrinopeptide A concentration, and risk of coronary heart disease in men. Circulation 102:2058-2062
-
(2000)
Circulation
, vol.102
, pp. 2058-2062
-
-
Zito, F.1
Drummond, F.2
Bujac, S.R.3
Esnouf, M.P.4
Morrissey, J.H.5
Humphries, S.E.6
Miller, G.J.7
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