Rapid and efficient synthesis of 1,2,4-oxadiazoles utilizing polymer-supported reagents under microwave heating

Organic Letters

Volumn 7, Issue 5, 2005, Pages 925-928

  Wang, Ying ^a   Miller, Reagan L ^a,b   Sauer, Daryl R ^a   Djuric, Stevan W ^a  

^a ABBOTT LABORATORIES   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4 OXADIAZOLE DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; OXIME DERIVATIVE; POLYMER; REAGENT;

ARTICLE; METHODOLOGY; MICROWAVE COOKING; SYNTHESIS;

CARBOXYLIC ACIDS; CATALYSIS; INDICATORS AND REAGENTS; MICROWAVES; MOLECULAR STRUCTURE; OXADIAZOLES; OXIMES;

EID: 15044363597     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol050007r     Document Type: Article

References (35)

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27. All microwave reactions were performed on an Emrys Optimizer (Personal Chemistry, http://www.personalchemistry).
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34. Unpublished results.
35. Partial conversion to 1,2,4-oxadiazoles was observed with 3 equiv of PS-DIEA or PS-Carbonate. Comparable yields of 1,2,4-oxadiazoles were obtained when 3 equiv of PS-BEMP was used in place of DIEA.