Design, synthesis, and evaluation of Phe-Gly mimetics: Heterocyclic building blocks for pseudopeptides

Journal of Medicinal Chemistry

Volumn 42, Issue 21, 1999, Pages 4331-4342

  Borg, Susanna ^a   Vollinga, Roeland C ^a   Labarre, Maryse ^b   Payza, Kemal ^b   Terenius, Lars ^c   Luthman, Kristina ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b Astra Research Centre Montreal   (Canada)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4 OXADIAZOLE DERIVATIVE; 1,2,4 TRIAZOLE DERIVATIVE; 1,3,4 OXADIAZOLE DERIVATIVE; DERMORPHIN; HETEROCYCLIC COMPOUND; MU OPIATE RECEPTOR AGONIST; NEUROKININ 1 RECEPTOR; PHENYLGLYCINE DERIVATIVE; SUBSTANCE P; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; DRUG CONFORMATION; DRUG DESIGN; DRUG SYNTHESIS; NONHUMAN; PEPTIDE SYNTHESIS; RAT; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ANIMALS; BRAIN; CELL LINE; DIPEPTIDES; DRUG DESIGN; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR MIMICRY; OLIGOPEPTIDES; OXADIAZOLES; RADIOLIGAND ASSAY; RATS; RECEPTORS, NEUROKININ-1; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU; TRIAZOLES;

EID: 0032748596     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990197+     Document Type: Article

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