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Volumn 48, Issue 1, 2005, Pages 47-57

Cyclooxygenase-2 protein levels are independent of epidermal growth factor receptor expression or activation in operable non-small cell lung cancer

Author keywords

Cyclooxygenase (COX) 2; Epidermal growth factor (EGF); Epidermal growth factor receptor (EGFR); Immunohistochemistry; Non small cell lung cancer (NSCLC); Prognosis

Indexed keywords

CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR;

EID: 15044361542     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2004.09.007     Document Type: Article
Times cited : (21)

References (49)
  • 3
    • 0034901568 scopus 로고    scopus 로고
    • Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer
    • F.R. Khuri, H. Wu, J.J. Lee, B.L. Kemp, R. Lotan, and S.M. Lippman Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer Clin Cancer Res 7 2001 861 867
    • (2001) Clin Cancer Res , vol.7 , pp. 861-867
    • Khuri, F.R.1    Wu, H.2    Lee, J.J.3    Kemp, B.L.4    Lotan, R.5    Lippman, S.M.6
  • 4
    • 0025998557 scopus 로고
    • Aspirin use and reduced risk of fatal colon cancer
    • M.J. Thun, M.M. Namboodiri, and C.W. Heath Jr. Aspirin use and reduced risk of fatal colon cancer N Engl J Med 325 1991 1593 1596
    • (1991) N Engl J Med , vol.325 , pp. 1593-1596
    • Thun, M.J.1    Namboodiri, M.M.2    Heath Jr., C.W.3
  • 6
    • 0033761153 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression correlates with tumor neovascularization and prognosis in human colorectal carcinoma patients
    • R. Masunaga, H. Kohno, D.K. Dhar, S. Ohno, M. Shibakita, and S. Kinugasa Cyclooxygenase-2 expression correlates with tumor neovascularization and prognosis in human colorectal carcinoma patients Clin Cancer Res 6 2000 4064 4068
    • (2000) Clin Cancer Res , vol.6 , pp. 4064-4068
    • Masunaga, R.1    Kohno, H.2    Dhar, D.K.3    Ohno, S.4    Shibakita, M.5    Kinugasa, S.6
  • 7
    • 0033923699 scopus 로고    scopus 로고
    • Cyclooxygenase-2 overexpression correlates with tumour recurrence, especially haematogenous metastasis, of colorectal cancer
    • S. Tomozawa, N.H. Tsuno, E. Sunami, K. Hatano, J. Kitayama, and T. Osada Cyclooxygenase-2 overexpression correlates with tumour recurrence, especially haematogenous metastasis, of colorectal cancer Br J Cancer 83 2000 324 328
    • (2000) Br J Cancer , vol.83 , pp. 324-328
    • Tomozawa, S.1    Tsuno, N.H.2    Sunami, E.3    Hatano, K.4    Kitayama, J.5    Osada, T.6
  • 8
    • 0043066734 scopus 로고    scopus 로고
    • Prognostic significance of expression of cyclooxygenase-2 and vascular endothelial growth factor in human gastric carcinoma
    • H. Shi, J.M. Xu, N.Z. Hu, H.J. Xie, C.J. Buskens, and B.P. Van Rees Prognostic significance of expression of cyclooxygenase-2 and vascular endothelial growth factor in human gastric carcinoma World J Gastroenterol 9 2003 1421 1426
    • (2003) World J Gastroenterol , vol.9 , pp. 1421-1426
    • Shi, H.1    Xu, J.M.2    Hu, N.Z.3    Xie, H.J.4    Buskens, C.J.5    Van Rees, B.P.6
  • 9
    • 0036083347 scopus 로고    scopus 로고
    • Prognostic significance of elevated cyclooxygenase 2 expression in patients with adenocarcinoma of the esophagus
    • C.J. Buskens, B.P. Van Rees, A. Sivula, J.B. Reitsma, C. Haglund, and P.J. Bosma Prognostic significance of elevated cyclooxygenase 2 expression in patients with adenocarcinoma of the esophagus Gastroenterology 122 2002 1800 1807
    • (2002) Gastroenterology , vol.122 , pp. 1800-1807
    • Buskens, C.J.1    Van Rees, B.P.2    Sivula, A.3    Reitsma, J.B.4    Haglund, C.5    Bosma, P.J.6
  • 10
    • 0037910076 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is associated with well-differentiated and intestinal-type pathways in gastric carcinogenesis
    • Y.E. Joo, W.T. Oh, J.S. Rew, C.S. Park, S.K. Choi, and S.J. Kim Cyclooxygenase-2 expression is associated with well-differentiated and intestinal-type pathways in gastric carcinogenesis Digestion 66 2002 222 229
    • (2002) Digestion , vol.66 , pp. 222-229
    • Joo, Y.E.1    Oh, W.T.2    Rew, J.S.3    Park, C.S.4    Choi, S.K.5    Kim, S.J.6
  • 11
    • 0032948381 scopus 로고    scopus 로고
    • Prognostic significance of elevated cyclooxygenase 2 expression in primary, resected lung adenocarcinomas
    • H. Achiwa, Y. Yatabe, T. Hida, T. Kuroishi, K. Kozaki, and S. Nakamura Prognostic significance of elevated cyclooxygenase 2 expression in primary, resected lung adenocarcinomas Clin Cancer Res 5 1999 1001 1005
    • (1999) Clin Cancer Res , vol.5 , pp. 1001-1005
    • Achiwa, H.1    Yatabe, Y.2    Hida, T.3    Kuroishi, T.4    Kozaki, K.5    Nakamura, S.6
  • 12
    • 0034488632 scopus 로고    scopus 로고
    • Nitric oxide synthase, cyclooxygenase 2, and vascular endothelial growth factor in the angiogenesis of non-small cell lung carcinoma
    • A.J. Marrogi, W.D. Travis, J.A. Welsh, M.A. Khan, H. Rahim, and H. Tazelaar Nitric oxide synthase, cyclooxygenase 2, and vascular endothelial growth factor in the angiogenesis of non-small cell lung carcinoma Clin Cancer Res 6 2000 4739 4744
    • (2000) Clin Cancer Res , vol.6 , pp. 4739-4744
    • Marrogi, A.J.1    Travis, W.D.2    Welsh, J.A.3    Khan, M.A.4    Rahim, H.5    Tazelaar, H.6
  • 13
    • 0033735989 scopus 로고    scopus 로고
    • Increased cyclooxygenase 2 (COX-2) expression occurs frequently in precursor lesions of human adenocarcinoma of the lung
    • Y. Hosomi, T. Yokose, Y. Hirose, R. Nakajima, K. Nagai, and Y. Nishiwaki Increased cyclooxygenase 2 (COX-2) expression occurs frequently in precursor lesions of human adenocarcinoma of the lung Lung Cancer 30 2000 73 81
    • (2000) Lung Cancer , vol.30 , pp. 73-81
    • Hosomi, Y.1    Yokose, T.2    Hirose, Y.3    Nakajima, R.4    Nagai, K.5    Nishiwaki, Y.6
  • 16
    • 0033199017 scopus 로고    scopus 로고
    • Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: Growth inhibition by nonsteroidal anti-inflammatory drugs
    • M.A. Molina, M. Sitja-Arnau, M.G. Lemoine, M.L. Frazier, and F.A. Sinicrope Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: growth inhibition by nonsteroidal anti-inflammatory drugs Cancer Res 59 1999 4356 4362
    • (1999) Cancer Res , vol.59 , pp. 4356-4362
    • Molina, M.A.1    Sitja-Arnau, M.2    Lemoine, M.G.3    Frazier, M.L.4    Sinicrope, F.A.5
  • 17
    • 0037214178 scopus 로고    scopus 로고
    • Epidermal growth factor receptors and cyclooxygenase-2 in the pathogenesis of non-small cell lung cancer: Potential targets for chemoprevention and systemic therapy
    • C.M. Richardson, R.A. Sharma, G. Cox, and K.J. O'Byrne Epidermal growth factor receptors and cyclooxygenase-2 in the pathogenesis of non-small cell lung cancer: potential targets for chemoprevention and systemic therapy Lung Cancer 39 2003 1 13
    • (2003) Lung Cancer , vol.39 , pp. 1-13
    • Richardson, C.M.1    Sharma, R.A.2    Cox, G.3    O'Byrne, K.J.4
  • 18
    • 0032867341 scopus 로고    scopus 로고
    • Regulation of cyclooxygenase-2 by interferon gamma and transforming growth factor alpha in normal human epidermal keratinocytes and squamous carcinoma cells. Role of mitogen-activated protein kinases
    • H. Matsuura, M. Sakaue, K. Subbaramaiah, H. Kamitani, T.E. Eling, and A.J. Dannenberg Regulation of cyclooxygenase-2 by interferon gamma and transforming growth factor alpha in normal human epidermal keratinocytes and squamous carcinoma cells. Role of mitogen-activated protein kinases J Biol Chem 274 1999 29138 29148
    • (1999) J Biol Chem , vol.274 , pp. 29138-29148
    • Matsuura, H.1    Sakaue, M.2    Subbaramaiah, K.3    Kamitani, H.4    Eling, T.E.5    Dannenberg, A.J.6
  • 19
    • 12644261426 scopus 로고    scopus 로고
    • Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells
    • R.J. Coffey, C.J. Hawkey, L. Damstrup, R. Graves-Deal, V.C. Daniel, and P.J. Dempsey Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells Proc Natl Acad Sci USA 94 1997 657 662
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 657-662
    • Coffey, R.J.1    Hawkey, C.J.2    Damstrup, L.3    Graves-Deal, R.4    Daniel, V.C.5    Dempsey, P.J.6
  • 20
    • 0033290356 scopus 로고    scopus 로고
    • Synergistic induction of cyclooxygenase-2 by transforming growth factor-beta1 and epidermal growth factor inhibits apoptosis in epithelial cells
    • D. Saha, P.K. Datta, H. Sheng, J.D. Morrow, M. Wada, and H.L. Moses Synergistic induction of cyclooxygenase-2 by transforming growth factor-beta1 and epidermal growth factor inhibits apoptosis in epithelial cells Neoplasia 1 1999 508 517
    • (1999) Neoplasia , vol.1 , pp. 508-517
    • Saha, D.1    Datta, P.K.2    Sheng, H.3    Morrow, J.D.4    Wada, M.5    Moses, H.L.6
  • 21
    • 0036006453 scopus 로고    scopus 로고
    • 2 transactivates EGF receptor: A novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy
    • 2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy Nat Med 8 2002 289 293
    • (2002) Nat Med , vol.8 , pp. 289-293
    • Pai, R.1    Soreghan, B.2    Szabo, I.L.3    Pavelka, M.4    Baatar, D.5    Tarnawski, A.S.6
  • 22
    • 0037386939 scopus 로고    scopus 로고
    • Combination of a selective cyclooxygenase-2 inhibitor with epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 and protein kinase a antisense causes cooperative antitumor and antiangiogenic effect
    • G. Tortora, R. Caputo, V. Damiano, D. Melisi, R. Bianco, and G. Fontanini Combination of a selective cyclooxygenase-2 inhibitor with epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 and protein kinase A antisense causes cooperative antitumor and antiangiogenic effect Clin Cancer Res 9 2003 1566 1572
    • (2003) Clin Cancer Res , vol.9 , pp. 1566-1572
    • Tortora, G.1    Caputo, R.2    Damiano, V.3    Melisi, D.4    Bianco, R.5    Fontanini, G.6
  • 23
    • 0021134481 scopus 로고
    • Human squamous cell carcinomas express increased epidermal growth factor receptors
    • F. Hendler, and B. Ozanne Human squamous cell carcinomas express increased epidermal growth factor receptors J Clin Invest 74 1984 651 674
    • (1984) J Clin Invest , vol.74 , pp. 651-674
    • Hendler, F.1    Ozanne, B.2
  • 24
    • 0027232422 scopus 로고
    • The relationship of quantitative epidermal growth factor receptor receptor expression in non-small cell lung cancer to long term survival
    • D. Veale, N. Kerr, G.J. Gibson, P.J. Kelly, and A.L. Harris The relationship of quantitative epidermal growth factor receptor receptor expression in non-small cell lung cancer to long term survival Br J Cancer 68 1993 162 165
    • (1993) Br J Cancer , vol.68 , pp. 162-165
    • Veale, D.1    Kerr, N.2    Gibson, G.J.3    Kelly, P.J.4    Harris, A.L.5
  • 25
    • 18644377457 scopus 로고    scopus 로고
    • The role of EGF-R expression on patient survival in lung cancer: A systematic review with meta-analysis
    • A.P. Meert, B. Martin, P. Delmotte, T. Berghmans, J.J. Lafitte, and C. Mascaux The role of EGF-R expression on patient survival in lung cancer: a systematic review with meta-analysis Eur Respir J 20 2002 975 981
    • (2002) Eur Respir J , vol.20 , pp. 975-981
    • Meert, A.P.1    Martin, B.2    Delmotte, P.3    Berghmans, T.4    Lafitte, J.J.5    Mascaux, C.6
  • 26
    • 18744434862 scopus 로고    scopus 로고
    • Epidermal growth factor receptor expression correlates with poor prognosis in non-small cell lung cancer patients with p53 overexpression
    • Y. Ohsaki, S. Tanno, Y. Fujita, E. Toyoshima, S. Fujiuchi, and Y. Nishigaki Epidermal growth factor receptor expression correlates with poor prognosis in non-small cell lung cancer patients with p53 overexpression Oncol Rep 7 2000 603 607
    • (2000) Oncol Rep , vol.7 , pp. 603-607
    • Ohsaki, Y.1    Tanno, S.2    Fujita, Y.3    Toyoshima, E.4    Fujiuchi, S.5    Nishigaki, Y.6
  • 28
    • 0036098022 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2), epidermal growth factor receptor (EGFR), and Her-2/neu expression in ovarian cancer
    • G. Ferrandina, F.O. Ranelletti, L. Lauriola, F. Fanfani, F. Legge, and M. Mottolese Cyclooxygenase-2 (COX-2), epidermal growth factor receptor (EGFR), and Her-2/neu expression in ovarian cancer Gynecol Oncol 85 2002 305 310
    • (2002) Gynecol Oncol , vol.85 , pp. 305-310
    • Ferrandina, G.1    Ranelletti, F.O.2    Lauriola, L.3    Fanfani, F.4    Legge, F.5    Mottolese, M.6
  • 30
    • 12144290754 scopus 로고    scopus 로고
    • Synchronous coexpression of epidermal growth factor receptor and cyclooxygenase-2 in carcinomas of the uterine cervix: A potential predictor of poor survival
    • G.E. Kim, Y.B. Kim, N.H. Cho, H.C. Chung, H.R. Pyo, and J.D. Lee Synchronous coexpression of epidermal growth factor receptor and cyclooxygenase-2 in carcinomas of the uterine cervix: a potential predictor of poor survival Clin Cancer Res 10 2004 1366 1374
    • (2004) Clin Cancer Res , vol.10 , pp. 1366-1374
    • Kim, G.E.1    Kim, Y.B.2    Cho, N.H.3    Chung, H.C.4    Pyo, H.R.5    Lee, J.D.6
  • 31
    • 0036121416 scopus 로고    scopus 로고
    • Frequent co-localization of Cox-2 and laminin-5 gamma2 chain at the invasive front of early-stage lung adenocarcinomas
    • T. Niki, T. Kohno, S. Iba, Y. Moriya, Y. Takahashi, and M. Saito Frequent co-localization of Cox-2 and laminin-5 gamma2 chain at the invasive front of early-stage lung adenocarcinomas Am J Pathol 160 2002 1129 1141
    • (2002) Am J Pathol , vol.160 , pp. 1129-1141
    • Niki, T.1    Kohno, T.2    Iba, S.3    Moriya, Y.4    Takahashi, Y.5    Saito, M.6
  • 32
    • 0032170955 scopus 로고    scopus 로고
    • Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas
    • T. Hida, Y. Yatabe, H. Achiwa, H. Muramatsu, K. Kozaki, and S. Nakamura Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas Cancer Res 58 1998 3761 3764
    • (1998) Cancer Res , vol.58 , pp. 3761-3764
    • Hida, T.1    Yatabe, Y.2    Achiwa, H.3    Muramatsu, H.4    Kozaki, K.5    Nakamura, S.6
  • 33
    • 0142011063 scopus 로고    scopus 로고
    • Correlation between cyclooxygenase-2 and tumor angiogenesis in non-small cell lung cancer
    • H.S. Kim, H.R. Youm, J.S. Lee, K.W. Min, J.H. Chung, and C.S. Park Correlation between cyclooxygenase-2 and tumor angiogenesis in non-small cell lung cancer Lung Cancer 42 2003 163 170
    • (2003) Lung Cancer , vol.42 , pp. 163-170
    • Kim, H.S.1    Youm, H.R.2    Lee, J.S.3    Min, K.W.4    Chung, J.H.5    Park, C.S.6
  • 34
    • 0036191910 scopus 로고    scopus 로고
    • Prognostic significance of cyclooxygenase 2 mRNA expression in non-small cell lung cancer
    • J. Brabender, J. Park, R. Metzger, P.M. Schneider, R.V. Lord, and A.H. Holscher Prognostic significance of cyclooxygenase 2 mRNA expression in non-small cell lung cancer Ann Surg 235 2002 440 443
    • (2002) Ann Surg , vol.235 , pp. 440-443
    • Brabender, J.1    Park, J.2    Metzger, R.3    Schneider, P.M.4    Lord, R.V.5    Holscher, A.H.6
  • 35
    • 9144221378 scopus 로고    scopus 로고
    • COX-2, MMP-9, and Noguchi classification provide additional prognostic information about adenocarcinoma of the lung
    • N.H. Yamaguchi, A.J. Lichtenfels, L.M. Demarchi, A.P. da Silva, A.L. Garippo, and V.F. Alves COX-2, MMP-9, and Noguchi classification provide additional prognostic information about adenocarcinoma of the lung Am J Clin Pathol 121 2004 78 86
    • (2004) Am J Clin Pathol , vol.121 , pp. 78-86
    • Yamaguchi, N.H.1    Lichtenfels, A.J.2    Demarchi, L.M.3    Da Silva, A.P.4    Garippo, A.L.5    Alves, V.F.6
  • 36
    • 0035409904 scopus 로고    scopus 로고
    • IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody, for treatment of head and neck cancer
    • R.S. Herbst, and P.M. Kim ESHarari IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody, for treatment of head and neck cancer Expert Opin Biol Ther 1 2001 719 732
    • (2001) Expert Opin Biol Ther , vol.1 , pp. 719-732
    • Herbst, R.S.1    Kim Esharari, P.M.2
  • 37
    • 0036809621 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and bladder cancer
    • A.J. Colquhoun, and J.K. Mellon Epidermal growth factor receptor and bladder cancer Postgrad Med J 78 2002 584 589
    • (2002) Postgrad Med J , vol.78 , pp. 584-589
    • Colquhoun, A.J.1    Mellon, J.K.2
  • 38
    • 0036682406 scopus 로고    scopus 로고
    • Overexpression of cyclooxygenase-2 is associated with a poor prognosis in patients with squamous cell carcinoma of the uterine cervix treated with radiation and concurrent chemotherapy
    • Y.B. Kim, G.E. Kim, N.H. Cho, H.R. Pyo, S.J. Shim, and S.K. Chang Overexpression of cyclooxygenase-2 is associated with a poor prognosis in patients with squamous cell carcinoma of the uterine cervix treated with radiation and concurrent chemotherapy Cancer 95 2002 531 539
    • (2002) Cancer , vol.95 , pp. 531-539
    • Kim, Y.B.1    Kim, G.E.2    Cho, N.H.3    Pyo, H.R.4    Shim, S.J.5    Chang, S.K.6
  • 39
    • 9144256014 scopus 로고    scopus 로고
    • Epidermal growth factor receptor overexpression correlates with a poor prognosis in completely resected non-small-cell lung cancer
    • G. Selvaggi, S. Novello, V. Torri, E. Leonardo, P. De Giuli, and P. Borasio Epidermal growth factor receptor overexpression correlates with a poor prognosis in completely resected non-small-cell lung cancer Ann Oncol 15 2004 28 32
    • (2004) Ann Oncol , vol.15 , pp. 28-32
    • Selvaggi, G.1    Novello, S.2    Torri, V.3    Leonardo, E.4    De Giuli, P.5    Borasio, P.6
  • 40
    • 0030005871 scopus 로고    scopus 로고
    • Angiogenesis and molecular biologic substaging in patients with stage I non-small cell lung cancer
    • D.H. Harpole Jr., W.G. Richards, J.E. Herndon, and D.J. Sugarbaker Angiogenesis and molecular biologic substaging in patients with stage I non-small cell lung cancer Ann Thorac Surg 61 1996 1470 1476
    • (1996) Ann Thorac Surg , vol.61 , pp. 1470-1476
    • Harpole Jr., D.H.1    Richards, W.G.2    Herndon, J.E.3    Sugarbaker, D.J.4
  • 41
    • 0030054716 scopus 로고    scopus 로고
    • Lack of prognostic significance of epidermal growth factor receptor and the oncoprotein p185HER-2 in patients with systemically untreated non-small-cell lung cancer: An immunohistochemical study on cryosections
    • P. Pfeiffer, P.P. Clausen, K. Andersen, and C. Rose Lack of prognostic significance of epidermal growth factor receptor and the oncoprotein p185HER-2 in patients with systemically untreated non-small-cell lung cancer: an immunohistochemical study on cryosections Br. J. Cancer 74 1996 86 91
    • (1996) Br. J. Cancer , vol.74 , pp. 86-91
    • Pfeiffer, P.1    Clausen, P.P.2    Andersen, K.3    Rose, C.4
  • 42
    • 0027159063 scopus 로고
    • Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung
    • V. Rusch, J. Baselga, C. Cordon-Cardo, J. Orazem, M. Zaman, and S. Hoda Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung Cancer Res 53 1993 2379 2385
    • (1993) Cancer Res , vol.53 , pp. 2379-2385
    • Rusch, V.1    Baselga, J.2    Cordon-Cardo, C.3    Orazem, J.4    Zaman, M.5    Hoda, S.6
  • 43
    • 0034042621 scopus 로고    scopus 로고
    • Matrix metalloproteinase 9 and the epidermal growth factor signal pathway in operable non-small cell lung cancer
    • G. Cox, J.L. Jones, and K.J. O'Byrne Matrix metalloproteinase 9 and the epidermal growth factor signal pathway in operable non-small cell lung cancer Clin Cancer Res 6 2000 2349 2355
    • (2000) Clin Cancer Res , vol.6 , pp. 2349-2355
    • Cox, G.1    Jones, J.L.2    O'Byrne, K.J.3
  • 44
    • 0028937815 scopus 로고
    • Epidermal growth factor receptor (EGFr) expression in non-small cell lung carcinomas correlates with metastatic involvement of hilar and mediastinal lymph nodes in the squamous subtype
    • G. Fontanini, S. Vignati, D. Bigini, A. Mussi, H. Lucchi, and C.A. Angeletti Epidermal growth factor receptor (EGFr) expression in non-small cell lung carcinomas correlates with metastatic involvement of hilar and mediastinal lymph nodes in the squamous subtype Eur J Cancer 31A 1995 178 183
    • (1995) Eur J Cancer , vol.31 , pp. 178-183
    • Fontanini, G.1    Vignati, S.2    Bigini, D.3    Mussi, A.4    Lucchi, H.5    Angeletti, C.A.6
  • 45
    • 0023261096 scopus 로고
    • Epidermal growth factor receptors in non-small cell lung cancer
    • D. Veale, T. Ashcroft, C. Marsh, G.J. Gibson, and A.L. Harris Epidermal growth factor receptors in non-small cell lung cancer Br J Cancer 55 1987 513 516
    • (1987) Br J Cancer , vol.55 , pp. 513-516
    • Veale, D.1    Ashcroft, T.2    Marsh, C.3    Gibson, G.J.4    Harris, A.L.5
  • 47
    • 0034693634 scopus 로고    scopus 로고
    • Co-expression of epidermal growth factor receptor and transforming growth factor-alpha predicts worse prognosis in breast-cancer patients
    • Y. Umekita, Y. Ohi, Y. Sagara, and H. Yoshida Co-expression of epidermal growth factor receptor and transforming growth factor-alpha predicts worse prognosis in breast-cancer patients Int J Cancer 89 2000 484 487
    • (2000) Int J Cancer , vol.89 , pp. 484-487
    • Umekita, Y.1    Ohi, Y.2    Sagara, Y.3    Yoshida, H.4
  • 48
    • 1642453746 scopus 로고    scopus 로고
    • Synchronous overexpression of epidermal growth factor receptor and HER2-neu protein is a predictor of poor outcome in patients with stage I non-small cell lung cancer
    • A. Onn, A.M. Correa, M. Gilcrease, T. Isobe, E. Massarelli, and C.D. Bucana Synchronous overexpression of epidermal growth factor receptor and HER2-neu protein is a predictor of poor outcome in patients with stage I non-small cell lung cancer Clin Cancer Res 10 2004 136 143
    • (2004) Clin Cancer Res , vol.10 , pp. 136-143
    • Onn, A.1    Correa, A.M.2    Gilcrease, M.3    Isobe, T.4    Massarelli, E.5    Bucana, C.D.6
  • 49
    • 0029053421 scopus 로고
    • Expression and activation of erbB-2 and epidermal growth factor receptor in lung adenocarcinomas
    • W.J. Rachwal, P.F. Bongiorno, M.B. Orringer, R.I. Whyte, S.P. Ethier, and D.G. Beer Expression and activation of erbB-2 and epidermal growth factor receptor in lung adenocarcinomas Br J Cancer 72 1995 56 64
    • (1995) Br J Cancer , vol.72 , pp. 56-64
    • Rachwal, W.J.1    Bongiorno, P.F.2    Orringer, M.B.3    Whyte, R.I.4    Ethier, S.P.5    Beer, D.G.6


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