Functional applications of novel Semliki Forest virus vectors are limited by vector toxicity in cultures of primary neurons in vitro and in the substantia nigra in vivo

Experimental Brain Research

Volumn 161, Issue 3, 2005, Pages 335-342

  Lingor, Paul ^a   Schöll, Ulrike ^a   Bähr, Mathias ^a   Kügler, Sebastian ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Dopaminergic neurons; Gene transfer; Viral vectors

Indexed keywords

PROTEIN BCL XL; VIRUS VECTOR; X LINKED INHIBITOR OF APOPTOSIS;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL POPULATION; CELL TYPE; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSDUCTION; MESENCEPHALON; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEMLIKI FOREST ALPHAVIRUS; SUBSTANTIA NIGRA; TRANSGENE; VIRUS INFECTION;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; APOPTOSIS; BCL-X PROTEIN; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DOPAMINE; FEMALE; GENE EXPRESSION REGULATION, VIRAL; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; NERVE DEGENERATION; NEURONS; PARKINSONIAN DISORDERS; PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; SEMLIKI FOREST VIRUS; SUBSTANTIA NIGRA; TRANSDUCTION, GENETIC; TRANSGENES; TREATMENT OUTCOME; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 15044358149     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00221-004-2077-9     Document Type: Article

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