Human synapsin 1 gene promoter confers highly neuron-specific long-term transgene expression from an adenoviral vector in the adult rat brain depending on the transduced area

Gene Therapy

Volumn 10, Issue 4, 2003, Pages 337-347

  Kugler S ^a   Kilic, E ^a   Bahr M ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Adenovirus; Brain; Dopaminergic neurons; Synapsin promoter; Targeted expression

Indexed keywords

ADENOVIRUS VECTOR; SMALL NUCLEAR RNA; SYNAPSIN I;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BRAIN TISSUE; CLINICAL PROTOCOL; CONTROLLED STUDY; CORPUS STRIATUM; CYTOMEGALOVIRUS; DEGENERATIVE DISEASE; DOPAMINERGIC NERVE CELL; DRUG SAFETY; GENE DELETION; GENE EXPRESSION; GENE TARGETING; GENE THERAPY; GENE TRANSFER; GENETIC TRANSDUCTION; GLIA CELL; HUMAN; IMMUNOGENICITY; MOLECULAR CLONING; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROMOTER REGION; RAT; REVIEW; SUBSTANTIA NIGRA; THALAMUS; TRANSCRIPTION REGULATION; TRANSGENE; VIRAL GENE DELIVERY SYSTEM; VIRUS ATTENUATION; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALS; BRAIN; FEMALE; GENE EXPRESSION; GENE TARGETING; GENE THERAPY; GENETIC VECTORS; MICROSCOPY, FLUORESCENCE; NEURONS; PROMOTER REGIONS (GENETICS); RATS; RATS, INBRED STRAINS; SYNAPSINS; TIME FACTORS; TRANSGENES;

ADENOVIRIDAE; ANIMALIA; CUCUMBER MOSAIC VIRUS; CYTOMEGALOVIRUS; RNA VIRUSES;

EID: 0037297303     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301905     Document Type: Review

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