The Semliki Forest virus vector induces p53-independent apoptosis

Journal of General Virology

Volumn 79, Issue 10, 1998, Pages 2405-2410

  Glasgow, Gwendoline M ^a   McGee, Margaret M ^a   Tarbatt, Catherine J ^a   Mooney, Dorothy A ^a   Sheahan, Brian J ^b   Atkins, Gregory J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; VIRUS RNA; VIRUS VECTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; DELETION MUTANT; EXPRESSION VECTOR; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; SEMLIKI FOREST ALPHAVIRUS; VIRUS GENOME; VIRUS MUTANT;

ALPHAVIRUS; ANIMALIA; RABBIT FIBROMA VIRUS; RNA VIRUSES; SEMLIKI FOREST VIRUS;

EID: 0031660130     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-79-10-2405     Document Type: Article

References (29)

1. Atkins, G. J. (1976). The effect of infection with Sindbis virus and its temperature-sensitive mutants on cellular protein and DNA synthesis. Virology 71, 593-597.
2. Atkins, G. J. (1977). Cytopathogenicity of temperature-sensitive mutants of Sindbis virus. FEMS Microbiology Letters 2, 51-55.
3. Atkins, G. J. (1979). Establishment of persistent infection in BHK-21 cells by temperature-sensitive mutants of Sindbis virus. Journal of General Virology 45, 201-207.
4. Atkins, G. J. & Lancashire, C. L. (1976). Interferon induction by temperature-sensitive mutants of Sindbis virus: its relationship to virus-specified double-stranded RNA synthesis and cytopathic effect. Journal of General Virology 30, 157-165.
5. Atkins, G. J., Sheahan, B. J. & Dimmock, N. J. (1985). Semliki Forest virus infection of mice: a model for genetic and molecular analysis of viral pathogenicity. Journal of General Virology 66, 395-408.
6. Atkins, G. J., Balluz, I. M., Glasgow, G. M., Mabruk., M. J. E. M. F., Natale, V. A. I., Smyth, J. M. B. & Sheahan, B. J. (1994). Analysis of the molecular basis of neuropathogenesis of RNA viruses in experimental animals: relevance for human disease? Neuropathology and Applied Neurobiology 20, 91-102.
7. Barrett, P. N. & Atkins, G. J. (1981). Establishment of persistent infection in mouse cells by temperature-sensitive mutants of Sindbis virus. Journal of General Virology 54, 57-65.
8. Berglund, P., Sjöberg, M., Atkins, G. J., Sheahan, B. J., Garoff, H. & Liljeström, P. (1993). Semliki Forest virus expression system: production of conditionally infectious recombinant particles. Nature Biotechnology 11, 916-920.
9. Fernandes, S. R. & Cotter, T. (1993). Activation of a calcium/ magnesium independent endonuclease in human leukemic cell apoptosis. Anti-Cancer Research 13, 1253-1260.
10. Frolov, I. & Schlesinger, S. (1994). Comparison of the effects of Sindbis virus and Sindbis virus replicons on host cell protein synthesis and cytopathogenicity in BHK cells. Journal of Virology 68, 1721-1727.
11. Fujiwara, T., Cai, D. W., Georges, R. N., Mukhopadhyay, T., Grimm, E. A. & Roth, J. A. (1994). Therapeutic effect of a retroviral wild-type p53 expression vector in an orthotopic lung cancer model. Journal of the National Cancer Institute 86, 1458-1462.
12. Gavrieli, Y., Sherman, Y. & Ben-Sasson, S. A. (1992). Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. Journal of Cell Biology 119, 493-501.
13. Glasgow, G. M., McGee, M. M., Mooney, D. A., Sheahan, B. J. & Atkins, G. J. (1997). Death mechanisms in cultured cells infected by Semliki Forest virus. Journal of General Virology 78, 1559-1563.
14. Grandgirard, D., Studer, E., Monney, L., Belser, T., Fellay, I., Borner, C. & Michel, M. R. (1998). Alphaviruses induce apoptosis in Bcl-2 overexpressing cells: evidence for a caspase-mediated, proteolytic inactivation of Bcl-2. EMBO Journal 17, 1268-1278.
15. Hockenbery, D. (1995). Defining apoptosis. American Journal of Pathology 146, 16-19.
16. Kibler, K. V., Shors, T., Perkins, K. B., Zeman, C. C, Banaszak, M. P., Biesterfeldt, J., Langland, J. O. & Jacobs, B. L. (1997). Double-stranded RNA is a trigger for apoptosis in vaccinia virus-infected cells. Journal of Virology 71, 1992-2003.
17. Levine, B., Huang, Q., Isaacs, J. T., Reed, J. C., Griffin, D. E. & Hardwick, J. M. (1993). Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene. Nature 361, 739-742.
18. Lee, S. B. & Estaban, M. (1994). The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis. Virology 199, 491-496.
19. Liljeström, P. & Garoff, H. (1991). A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Nature Biotechnology 9, 1356-1361.
20. Liljeström, P., Lusa, S., Huylebroek, D. & Garoff, H. (1991). In vitro mutagenesis of a full-length cDNA clone of Semliki Forest virus: the small 6,000-molecular weight membrane protein modulates virus release. Journal of Virology 65, 4107-4113.
21. Mundle, S. D. & Raza, A. (1995). The two in situ techniques do not differentiate between apoptosis and necrosis but rather reveal distinct patterns of DNA fragmentation in apoptosis. Laboratory Investigation 72, 611-613.
22. Natale, V. A. I., Sheahan, B. J. & Atkins, G. J. (1993). Effect of rubella virus infection on the development of rat cerebellar cells in culture. Neuropathology & Applied Neurobiology 19, 530-534.
23. Nava, V. E., Rosen, A., Veliuona, M. A., Clem, R. J., Levine, B. & Hardwick, J. M. (1998). Sindbis virus induces apoptosis through a caspase-dependent CrmA-sensitive pathway. Journal of Virology 72, 452-459.
24. Razvi, E. S. & Welsh, R. M. (1995). Apoptosis in viral infections. Advances in Virus Research 45, 1-60.
25. Scallan, M. F., Allsopp, T. E. & Fazakerley, J. K. ( 1997). bcl-2 acts early to restrict Semliki Forest virus replication and delays virus-induced programmed cell death. Journal of Virology 71, 1583-1590.
26. Strauss, J. H. & Strauss, E. G. (1994). The alphaviruses: gene expression, replication and evolution. Microbiological Reviews 58, 491-562.
27. Suomalainen, M., Liljestrom, P. & Garoff, H. (1992). Spike protein-nucleocapsid interactions drive the budding of alphaviruses. Journal of Virology 66, 4737-4747.
28. Takahashi, T., Nau, M. M., Chiba, I., Birrer, M. J., Rosenberg, R. K., Vinocour, M., Levitt, M., Pass, H., Gazdar, A. F. & Minna, J. D. (1989). p53: a frequent target for genetic abnormalities in lung cancer. Science 246, 491-494.
29. Ubol, S., Tucker, P. C., Griffin, D. E. & Hardwick, J. M. (1994). Neurovirulent strains of alphavirus induce apoptosis in bcl-2-expressing cells: role of a single amino acid change in the E2 glycoprotein. Proceedings of the National Academy of Sciences, USA 91, 5202-5206.