-
1
-
-
4644324025
-
Cancer immunotherapy: Moving beyond current vaccines
-
S.A. Rosenberg, J.C. Yang, and N.P. Restifo Cancer immunotherapy: moving beyond current vaccines Nat Med 10 2004 909 915
-
(2004)
Nat Med
, vol.10
, pp. 909-915
-
-
Rosenberg, S.A.1
Yang, J.C.2
Restifo, N.P.3
-
2
-
-
4344582378
-
Poor immunogenicity of a self/tumor antigen derives from peptide-MHC-I instability and is independent of tolerance
-
Z. Yu, M.R. Theoret, C.E. Touloukian, D.R. Surman, S.C. Garman, L. Feigenbaum, T.K. Baxter, B.M. Baker, and N.P. Restifo Poor immunogenicity of a self/tumor antigen derives from peptide-MHC-I instability and is independent of tolerance J Clin Invest 114 2004 551 559
-
(2004)
J Clin Invest
, vol.114
, pp. 551-559
-
-
Yu, Z.1
Theoret, M.R.2
Touloukian, C.E.3
Surman, D.R.4
Garman, S.C.5
Feigenbaum, L.6
Baxter, T.K.7
Baker, B.M.8
Restifo, N.P.9
-
3
-
-
14844334891
-
Breaking tolerance in cancer immunotherapy: Time to ACT
-
in press.
-
Overwijk WW: Breaking tolerance in cancer immunotherapy: time to ACT. Curr Opin Immunol 2005, 17: in press.
-
(2005)
Curr Opin Immunol
, vol.17
-
-
Overwijk, W.W.1
-
4
-
-
0037174674
-
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
-
M.E. Dudley, J.R. Wunderlich, P.F. Robbins, J.C. Yang, P. Hwu, D.J. Schwartzentruber, S.L. Topalian, R. Sherry, N.P. Restifo, and A.M. Hubicki Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes Science 298 2002 850 854
-
(2002)
Science
, vol.298
, pp. 850-854
-
-
Dudley, M.E.1
Wunderlich, J.R.2
Robbins, P.F.3
Yang, J.C.4
Hwu, P.5
Schwartzentruber, D.J.6
Topalian, S.L.7
Sherry, R.8
Restifo, N.P.9
Hubicki, A.M.10
-
5
-
-
5144226237
-
Cancer regression in patients with metastatic melanoma after the transfer of autologous antitumor lymphocytes
-
S.A. Rosenberg, and M.E. Dudley Cancer regression in patients with metastatic melanoma after the transfer of autologous antitumor lymphocytes Proc Natl Acad Sci USA 101 Suppl 2 2004 14639 14645
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.SUPPL. 2
, pp. 14639-14645
-
-
Rosenberg, S.A.1
Dudley, M.E.2
-
6
-
-
0034663776
-
Cutting edge: Naive T cells masquerading as memory cells
-
K. Murali-Krishna, and R. Ahmed Cutting edge: naive T cells masquerading as memory cells J Immunol 165 2000 1733 1737
-
(2000)
J Immunol
, vol.165
, pp. 1733-1737
-
-
Murali-Krishna, K.1
Ahmed, R.2
-
7
-
-
0034698931
-
Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation
-
A.W. Goldrath, L.Y. Bogatzki, and M.J. Bevan Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation J Exp Med 192 2000 557 564
-
(2000)
J Exp Med
, vol.192
, pp. 557-564
-
-
Goldrath, A.W.1
Bogatzki, L.Y.2
Bevan, M.J.3
-
8
-
-
0034698828
-
Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells
-
B.K. Cho, V.P. Rao, Q. Ge, H.N. Eisen, and J. Chen Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells J Exp Med 192 2000 549 556
-
(2000)
J Exp Med
, vol.192
, pp. 549-556
-
-
Cho, B.K.1
Rao, V.P.2
Ge, Q.3
Eisen, H.N.4
Chen, J.5
-
9
-
-
0033539516
-
Homeostatic expansion and phenotypic conversion of naive T cells in response to self peptide/MHC ligands
-
W.C. Kieper, and S.C. Jameson Homeostatic expansion and phenotypic conversion of naive T cells in response to self peptide/MHC ligands Proc Natl Acad Sci USA 96 1999 13306 13311
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13306-13311
-
-
Kieper, W.C.1
Jameson, S.C.2
-
10
-
-
0036076114
-
T cell homeostatic proliferation elicits effective antitumor autoimmunity
-
W. Dummer, A.G. Niethammer, R. Baccala, B.R. Lawson, N. Wagner, R.A. Reisfeld, and A.N. Theofilopoulos T cell homeostatic proliferation elicits effective antitumor autoimmunity J Clin Invest 110 2002 185 192
-
(2002)
J Clin Invest
, vol.110
, pp. 185-192
-
-
Dummer, W.1
Niethammer, A.G.2
Baccala, R.3
Lawson, B.R.4
Wagner, N.5
Reisfeld, R.A.6
Theofilopoulos, A.N.7
-
11
-
-
1942453326
-
Homeostatic expansion of T cells during immune insufficiency generates autoimmunity
-
C. King, A. Ilic, K. Koelsch, and N. Sarvetnick Homeostatic expansion of T cells during immune insufficiency generates autoimmunity Cell 117 2004 265 277
-
(2004)
Cell
, vol.117
, pp. 265-277
-
-
King, C.1
Ilic, A.2
Koelsch, K.3
Sarvetnick, N.4
-
12
-
-
0032586823
-
Naive cytotoxic T lymphocytes spontaneously acquire effector function in lymphocytopenic recipients: A pitfall for T cell memory studies?
-
S. Oehen, and K. Brduscha-Riem Naive cytotoxic T lymphocytes spontaneously acquire effector function in lymphocytopenic recipients: A pitfall for T cell memory studies? Eur J Immunol 29 1999 608 614
-
(1999)
Eur J Immunol
, vol.29
, pp. 608-614
-
-
Oehen, S.1
Brduscha-Riem, K.2
-
13
-
-
0041419656
-
Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells
-
W.W. Overwijk, M.R. Theoret, S.E. Finkelstein, D.R. Surman, L.A. de Jong, F.A. Vyth-Dreese, T.A. Dellemijn, P.A. Antony, P.J. Spiess, and D.C. Palmer Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells J Exp Med 198 2003 569 580
-
(2003)
J Exp Med
, vol.198
, pp. 569-580
-
-
Overwijk, W.W.1
Theoret, M.R.2
Finkelstein, S.E.3
Surman, D.R.4
De Jong, L.A.5
Vyth-Dreese, F.A.6
Dellemijn, T.A.7
Antony, P.A.8
Spiess, P.J.9
Palmer, D.C.10
-
14
-
-
0033136944
-
Designing and maintaining the mature TCR repertoire: The continuum of self-peptide:self-MHC complex recognition
-
C. Viret, F.S. Wong, and C.A. Janeway Jr. Designing and maintaining the mature TCR repertoire: the continuum of self-peptide:self-MHC complex recognition Immunity 10 1999 559 568
-
(1999)
Immunity
, vol.10
, pp. 559-568
-
-
Viret, C.1
Wong, F.S.2
Janeway Jr., C.A.3
-
15
-
-
0033180494
-
Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts
-
A.W. Goldrath, and M.J. Bevan Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts Immunity 11 1999 183 190
-
(1999)
Immunity
, vol.11
, pp. 183-190
-
-
Goldrath, A.W.1
Bevan, M.J.2
-
16
-
-
0033180491
-
The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery
-
B. Ernst, D.S. Lee, J.M. Chang, J. Sprent, and C.D. Surh The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery Immunity 11 1999 173 181
-
(1999)
Immunity
, vol.11
, pp. 173-181
-
-
Ernst, B.1
Lee, D.S.2
Chang, J.M.3
Sprent, J.4
Surh, C.D.5
-
17
-
-
0033517155
-
CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection
-
J. Bender, T. Mitchell, J. Kappler, and P. Marrack CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection J Exp Med 190 1999 367 374
-
(1999)
J Exp Med
, vol.190
, pp. 367-374
-
-
Bender, J.1
Mitchell, T.2
Kappler, J.3
Marrack, P.4
-
18
-
-
0035852769
-
Dependence of lymphopenia-induced T cell proliferation on the abundance of peptide/ MHC epitopes and strength of their interaction with T cell receptors
-
Q. Ge, V.P. Rao, B.K. Cho, H.N. Eisen, and J. Chen Dependence of lymphopenia-induced T cell proliferation on the abundance of peptide/ MHC epitopes and strength of their interaction with T cell receptors Proc Natl Acad Sci USA 98 2001 1728 1733
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 1728-1733
-
-
Ge, Q.1
Rao, V.P.2
Cho, B.K.3
Eisen, H.N.4
Chen, J.5
-
19
-
-
0034284220
-
Survival and homeostatic proliferation of naive peripheral CD4+ T cells in the absence of self peptide:MHC complexes
-
S.R. Clarke, and A.Y. Rudensky Survival and homeostatic proliferation of naive peripheral CD4+ T cells in the absence of self peptide:MHC complexes J Immunol 165 2000 2458 2464
-
(2000)
J Immunol
, vol.165
, pp. 2458-2464
-
-
Clarke, S.R.1
Rudensky, A.Y.2
-
20
-
-
0034305740
-
CD4+ T cell survival is not directly linked to self-MHC-induced TCR signaling
-
J.R. Dorfman, I. Stefanova, K. Yasutomo, and R.N. Germain CD4+ T cell survival is not directly linked to self-MHC-induced TCR signaling Nat Immunol 1 2000 329 335
-
(2000)
Nat Immunol
, vol.1
, pp. 329-335
-
-
Dorfman, J.R.1
Stefanova, I.2
Yasutomo, K.3
Germain, R.N.4
-
21
-
-
0037460071
-
Involvement of avidity for major histocompatibility complex in homeostasis of naive and memory T cells
-
G. Kassiotis, R. Zamoyska, and B. Stockinger Involvement of avidity for major histocompatibility complex in homeostasis of naive and memory T cells J Exp Med 197 2003 1007 1016
-
(2003)
J Exp Med
, vol.197
, pp. 1007-1016
-
-
Kassiotis, G.1
Zamoyska, R.2
Stockinger, B.3
-
22
-
-
0346103729
-
A role for TCR affinity in regulating naive T cell homeostasis
-
W.C. Kieper, J.T. Burghardt, and C.D. Surh A role for TCR affinity in regulating naive T cell homeostasis J Immunol 172 2004 40 44
-
(2004)
J Immunol
, vol.172
, pp. 40-44
-
-
Kieper, W.C.1
Burghardt, J.T.2
Surh, C.D.3
-
23
-
-
1642415714
-
Spontaneous proliferation, a response of naive CD4 T cells determined by the diversity of the memory cell repertoire
-
B. Min, G. Foucras, M. Meier-Schellersheim, and W.E. Paul Spontaneous proliferation, a response of naive CD4 T cells determined by the diversity of the memory cell repertoire Proc Natl Acad Sci USA 101 2004 3874 3879
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3874-3879
-
-
Min, B.1
Foucras, G.2
Meier-Schellersheim, M.3
Paul, W.E.4
-
24
-
-
0034529395
-
Peripheral T cell expansion in lymphopenic mice results in a restricted T cell repertoire
-
N.L. La Gruta, I.R. Driel, and P.A. Gleeson Peripheral T cell expansion in lymphopenic mice results in a restricted T cell repertoire Eur J Immunol 30 2000 3380 3386
-
(2000)
Eur J Immunol
, vol.30
, pp. 3380-3386
-
-
La Gruta, N.L.1
Driel, I.R.2
Gleeson, P.A.3
-
25
-
-
0037438341
-
Cutting edge: Homeostatic proliferation of peripheral T lymphocytes is regulated by clonal competition
-
A.E. Troy, and H. Shen Cutting edge: homeostatic proliferation of peripheral T lymphocytes is regulated by clonal competition J Immunol 170 2003 672 676
-
(2003)
J Immunol
, vol.170
, pp. 672-676
-
-
Troy, A.E.1
Shen, H.2
-
26
-
-
0037417794
-
Competition for self ligands restrains homeostatic proliferation of naive CD4 T cells
-
C.T. Moses, K.M. Thorstenson, S.C. Jameson, and A. Khoruts Competition for self ligands restrains homeostatic proliferation of naive CD4 T cells Proc Natl Acad Sci USA 100 2003 1185 1190
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1185-1190
-
-
Moses, C.T.1
Thorstenson, K.M.2
Jameson, S.C.3
Khoruts, A.4
-
27
-
-
10344261422
-
Cutting Edge: Persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy
-
P.F. Robbins, M.E. Dudley, J. Wunderlich, M. El-Gamil, Y.F. Li, J. Zhou, J. Huang, D.J. Powell Jr., and S.A. Rosenberg Cutting Edge: persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy J Immunol 173 2004 7125 7130 Lymphodepletion increases the persistence of adoptively transferred T cells. This paper furthermore shows a strong correlation between the rate of persistence of adoptively transferred T cells and induction of objective responses.
-
(2004)
J Immunol
, vol.173
, pp. 7125-7130
-
-
Robbins, P.F.1
Dudley, M.E.2
Wunderlich, J.3
El-Gamil, M.4
Li, Y.F.5
Zhou, J.6
Huang, J.7
Powell Jr., D.J.8
Rosenberg, S.A.9
-
28
-
-
0035889933
-
Homeostatic expansion occurs independently of costimulatory signals
-
M. Prlic, B.R. Blazar, A. Khoruts, T. Zell, and S.C. Jameson Homeostatic expansion occurs independently of costimulatory signals J Immunol 167 2001 5664 5668
-
(2001)
J Immunol
, vol.167
, pp. 5664-5668
-
-
Prlic, M.1
Blazar, B.R.2
Khoruts, A.3
Zell, T.4
Jameson, S.C.5
-
29
-
-
0035284861
-
Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients
-
B.R. Blazar, B.S. Kwon, A. Panoskaltsis-Mortari, K.B. Kwak, J.J. Peschon, and P.A. Taylor Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients J Immunol 166 2001 3174 3183
-
(2001)
J Immunol
, vol.166
, pp. 3174-3183
-
-
Blazar, B.R.1
Kwon, B.S.2
Panoskaltsis-Mortari, A.3
Kwak, K.B.4
Peschon, J.J.5
Taylor, P.A.6
-
30
-
-
7244261619
-
CD24 expression on T cells is required for optimal T cell proliferation in lymphopenic host
-
O. Li, P. Zheng, and Y. Liu CD24 expression on T cells is required for optimal T cell proliferation in lymphopenic host J Exp Med 200 2004 1083 1089
-
(2004)
J Exp Med
, vol.200
, pp. 1083-1089
-
-
Li, O.1
Zheng, P.2
Liu, Y.3
-
31
-
-
0034332403
-
Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo
-
K.S. Schluns, W.C. Kieper, S.C. Jameson, and L. Lefrancois Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo Nat Immunol 1 2000 426 432
-
(2000)
Nat Immunol
, vol.1
, pp. 426-432
-
-
Schluns, K.S.1
Kieper, W.C.2
Jameson, S.C.3
Lefrancois, L.4
-
32
-
-
0001585396
-
Control of homeostasis of CD8+ memory T cells by opposing cytokines
-
C.C. Ku, M. Murakami, A. Sakamoto, J. Kappler, and P. Marrack Control of homeostasis of CD8+ memory T cells by opposing cytokines Science 288 2000 675 678
-
(2000)
Science
, vol.288
, pp. 675-678
-
-
Ku, C.C.1
Murakami, M.2
Sakamoto, A.3
Kappler, J.4
Marrack, P.5
-
33
-
-
0035902513
-
IL-7 is critical for homeostatic proliferation and survival of naive T cells
-
J.T. Tan, E. Dudl, E. LeRoy, R. Murray, J. Sprent, K.I. Weinberg, and C.D. Surh IL-7 is critical for homeostatic proliferation and survival of naive T cells Proc Natl Acad Sci USA 98 2001 8732 8737
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8732-8737
-
-
Tan, J.T.1
Dudl, E.2
Leroy, E.3
Murray, R.4
Sprent, J.5
Weinberg, K.I.6
Surh, C.D.7
-
34
-
-
0037124362
-
Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells
-
A.W. Goldrath, P.V. Sivakumar, M. Glaccum, M.K. Kennedy, M.J. Bevan, C. Benoist, D. Mathis, and E.A. Butz Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells J Exp Med 195 2002 1515 1522
-
(2002)
J Exp Med
, vol.195
, pp. 1515-1522
-
-
Goldrath, A.W.1
Sivakumar, P.V.2
Glaccum, M.3
Kennedy, M.K.4
Bevan, M.J.5
Benoist, C.6
Mathis, D.7
Butz, E.A.8
-
35
-
-
0036786514
-
TCR and IL-7 receptor signals can operate independently or synergize to promote lymphopenia-induced expansion of naive T cells
-
B. Seddon, and R. Zamoyska TCR and IL-7 receptor signals can operate independently or synergize to promote lymphopenia-induced expansion of naive T cells J Immunol 169 2002 3752 3759
-
(2002)
J Immunol
, vol.169
, pp. 3752-3759
-
-
Seddon, B.1
Zamoyska, R.2
-
36
-
-
0028337496
-
Administration of recombinant human IL-7 to mice alters the composition of B-lineage cells and T cell subsets, enhances T cell function, and induces regression of established metastases
-
K.L. Komschlies, T.A. Gregorio, M.E. Gruys, T.C. Back, C.R. Faltynek, and R.H. Wiltrout Administration of recombinant human IL-7 to mice alters the composition of B-lineage cells and T cell subsets, enhances T cell function, and induces regression of established metastases J Immunol 152 1994 5776 5784
-
(1994)
J Immunol
, vol.152
, pp. 5776-5784
-
-
Komschlies, K.L.1
Gregorio, T.A.2
Gruys, M.E.3
Back, T.C.4
Faltynek, C.R.5
Wiltrout, R.H.6
-
37
-
-
4444374862
-
Recombinant interleukin-7 induces proliferation of naive macaque CD4+ and CD8+ T cells in vivo
-
M. Moniuszko, T. Fry, W.P. Tsai, M. Morre, B. Assouline, P. Cortez, M.G. Lewis, S. Cairns, C. Mackall, and G. Franchini Recombinant interleukin-7 induces proliferation of naive macaque CD4+ and CD8+ T cells in vivo J Virol 78 2004 9740 9749 This suggests that the application of IL-7 together with adoptively transferred tumor-reactive T cells in a lymphopenic host can augment tumor treatment potential.
-
(2004)
J Virol
, vol.78
, pp. 9740-9749
-
-
Moniuszko, M.1
Fry, T.2
Tsai, W.P.3
Morre, M.4
Assouline, B.5
Cortez, P.6
Lewis, M.G.7
Cairns, S.8
MacKall, C.9
Franchini, G.10
-
38
-
-
0035284827
-
IL-7 administration alters the CD4:CD8 ratio, increases T cell numbers, and increases T cell function in the absence of activation
-
L.A. Geiselhart, C.A. Humphries, T.A. Gregorio, S. Mou, J. Subleski, and K.L. Komschlies IL-7 administration alters the CD4:CD8 ratio, increases T cell numbers, and increases T cell function in the absence of activation J Immunol 166 2001 3019 3027
-
(2001)
J Immunol
, vol.166
, pp. 3019-3027
-
-
Geiselhart, L.A.1
Humphries, C.A.2
Gregorio, T.A.3
Mou, S.4
Subleski, J.5
Komschlies, K.L.6
-
39
-
-
0034992146
-
T lymphocytes need IL-7 but not IL-4 or IL-6 to survive in vivo
-
L. Vivien, C. Benoist, and D. Mathis T lymphocytes need IL-7 but not IL-4 or IL-6 to survive in vivo Int Immunol 13 2001 763 768
-
(2001)
Int Immunol
, vol.13
, pp. 763-768
-
-
Vivien, L.1
Benoist, C.2
Mathis, D.3
-
40
-
-
0033120051
-
Survival of naive CD4 T cells: Roles of restricting versus selecting MHC class II and cytokine milieu
-
T.E. Boursalian, and K. Bottomly Survival of naive CD4 T cells: roles of restricting versus selecting MHC class II and cytokine milieu J Immunol 162 1999 3795 3801
-
(1999)
J Immunol
, vol.162
, pp. 3795-3801
-
-
Boursalian, T.E.1
Bottomly, K.2
-
41
-
-
3042597040
-
IL-7 regulates basal homeostatic proliferation of antiviral CD4+T cell memory
-
D.C. Lenz, S.K. Kurz, E. Lemmens, S.P. Schoenberger, J. Sprent, M.B. Oldstone, and D. Homann IL-7 regulates basal homeostatic proliferation of antiviral CD4+T cell memory Proc Natl Acad Sci USA 101 2004 9357 9362
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9357-9362
-
-
Lenz, D.C.1
Kurz, S.K.2
Lemmens, E.3
Schoenberger, S.P.4
Sprent, J.5
Oldstone, M.B.6
Homann, D.7
-
42
-
-
5444239242
-
Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasis
-
P.R. Burkett, R. Koka, M. Chien, S. Chai, D.L. Boone, and A. Ma Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasis J Exp Med 200 2004 825 834
-
(2004)
J Exp Med
, vol.200
, pp. 825-834
-
-
Burkett, P.R.1
Koka, R.2
Chien, M.3
Chai, S.4
Boone, D.L.5
Ma, A.6
-
43
-
-
10744226452
-
IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells
-
C.A. Klebanoff, S.E. Finkelstein, D.R. Surman, M.K. Lichtman, L. Gattinoni, M.R. Theoret, N. Grewal, P.J. Spiess, P.A. Antony, and D.C. Palmer IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells Proc Natl Acad Sci USA 101 2004 1969 1974 The application of IL-15 as supportive cytokine in ACT could circumvent negative effects of the IL-2, which has been used to date, in a similar way to the induction of regulatory T cells.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 1969-1974
-
-
Klebanoff, C.A.1
Finkelstein, S.E.2
Surman, D.R.3
Lichtman, M.K.4
Gattinoni, L.5
Theoret, M.R.6
Grewal, N.7
Spiess, P.J.8
Antony, P.A.9
Palmer, D.C.10
-
44
-
-
19944434230
-
Synergy of IL-21 and IL-15 in regulating CD8+ T-cell expansion and function
-
+ cells, and can augment ACT when administered in vivo.
-
(2005)
J Exp Med
, vol.201
, pp. 139-148
-
-
Zeng, R.1
Spolski, R.2
Finkelstein, S.E.3
Oh, D.4
Kovanen, P.E.5
Hinrichs, C.S.6
Pise-Masison, C.A.7
Radonovich, M.F.8
Brady, J.N.9
Restifo, N.P.10
-
45
-
-
4644342928
-
Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells
-
M.J. Turk, J.A. Guevara-Patino, G.A. Rizzuto, M.E. Engelhorn, and A.N. Houghton Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells J Exp Med 200 2004 771 782
-
(2004)
J Exp Med
, vol.200
, pp. 771-782
-
-
Turk, M.J.1
Guevara-Patino, J.A.2
Rizzuto, G.A.3
Engelhorn, M.E.4
Houghton, A.N.5
-
46
-
-
0036858838
-
Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens
-
D. Golgher, E. Jones, F. Powrie, T. Elliott, and A. Gallimore Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens Eur J Immunol 32 2002 3267 3275
-
(2002)
Eur J Immunol
, vol.32
, pp. 3267-3275
-
-
Golgher, D.1
Jones, E.2
Powrie, F.3
Elliott, T.4
Gallimore, A.5
-
47
-
-
0033571105
-
Induction of tumor immunity by removing CD25+CD4+ T cells: A common basis between tumor immunity and autoimmunity
-
J. Shimizu, S. Yamazaki, and S. Sakaguchi Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity J Immunol 163 1999 5211 5218
-
(1999)
J Immunol
, vol.163
, pp. 5211-5218
-
-
Shimizu, J.1
Yamazaki, S.2
Sakaguchi, S.3
-
48
-
-
0344153890
-
CD4+/CD25+ regulatory cells inhibit activation of tumor-primed CD4+ T cells with IFN-gamma-dependent antiangiogenic activity, as well as long-lasting tumor immunity elicited by peptide vaccination
-
N. Casares, L. Arribillaga, P. Sarobe, J. Dotor, A. Lopez-Diaz de Cerio, I. Melero, J. Prieto, F. Borras-Cuesta, and J.J. Lasarte CD4+/CD25+ regulatory cells inhibit activation of tumor-primed CD4+ T cells with IFN-gamma-dependent antiangiogenic activity, as well as long-lasting tumor immunity elicited by peptide vaccination J Immunol 171 2003 5931 5939
-
(2003)
J Immunol
, vol.171
, pp. 5931-5939
-
-
Casares, N.1
Arribillaga, L.2
Sarobe, P.3
Dotor, J.4
Lopez-Diaz De Cerio, A.5
Melero, I.6
Prieto, J.7
Borras-Cuesta, F.8
Lasarte, J.J.9
-
49
-
-
1642497640
-
Tumor-specific human CD4+ regulatory T cells and their ligands: Implications for immunotherapy
-
+ T cells can be generated from tumor-infiltrating lymphocytes (TILs) in cancer patients. TILs showed suppressor activity and therefore might substantially inhibit T-cell anti-tumor action at the tumor site.
-
(2004)
Immunity
, vol.20
, pp. 107-118
-
-
Wang, H.Y.1
Lee, D.A.2
Peng, G.3
Guo, Z.4
Li, Y.5
Kiniwa, Y.6
Shevach, E.M.7
Wang, R.F.8
-
50
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
+ Treg cells from ovarian cancer patients suppress tumor-specific T-cell immunity, influence tumor growth and are associated with reduced survival.
-
(2004)
Nat Med
, vol.10
, pp. 942-949
-
-
Curiel, T.J.1
Coukos, G.2
Zou, L.3
Alvarez, X.4
Cheng, P.5
Mottram, P.6
Evdemon-Hogan, M.7
Conejo-Garcia, J.R.8
Zhang, L.9
Burow, M.10
-
51
-
-
0035874949
-
Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer
-
E.Y. Woo, C.S. Chu, T.J. Goletz, K. Schlienger, H. Yeh, G. Coukos, S.C. Rubin, L.R. Kaiser, and C.H. June Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer Cancer Res 61 2001 4766 4772
-
(2001)
Cancer Res
, vol.61
, pp. 4766-4772
-
-
Woo, E.Y.1
Chu, C.S.2
Goletz, T.J.3
Schlienger, K.4
Yeh, H.5
Coukos, G.6
Rubin, S.C.7
Kaiser, L.R.8
June, C.H.9
-
52
-
-
0036569127
-
Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation
-
E.Y. Woo, H. Yeh, C.S. Chu, K. Schlienger, R.G. Carroll, J.L. Riley, L.R. Kaiser, and C.H. June Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation J Immunol 168 2002 4272 4276
-
(2002)
J Immunol
, vol.168
, pp. 4272-4276
-
-
Woo, E.Y.1
Yeh, H.2
Chu, C.S.3
Schlienger, K.4
Carroll, R.G.5
Riley, J.L.6
Kaiser, L.R.7
June, C.H.8
-
53
-
-
0036721629
-
Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
-
U.K. Liyanage, T.T. Moore, H.G. Joo, Y. Tanaka, V. Herrmann, G. Doherty, J.A. Drebin, S.M. Strasberg, T.J. Eberlein, and P.S. Goedegebuure Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma J Immunol 169 2002 2756 2761
-
(2002)
J Immunol
, vol.169
, pp. 2756-2761
-
-
Liyanage, U.K.1
Moore, T.T.2
Joo, H.G.3
Tanaka, Y.4
Herrmann, V.5
Doherty, G.6
Drebin, J.A.7
Strasberg, S.M.8
Eberlein, T.J.9
Goedegebuure, P.S.10
-
54
-
-
0000448725
-
Modification of irradiation injury in mice and guinea pigs by bone marrow injections
-
E. Lorenz, D. Uphoff, T.R. Reid, and E. Shelton Modification of irradiation injury in mice and guinea pigs by bone marrow injections J Natl Cancer Inst 12 1951 197 201
-
(1951)
J Natl Cancer Inst
, vol.12
, pp. 197-201
-
-
Lorenz, E.1
Uphoff, D.2
Reid, T.R.3
Shelton, E.4
-
55
-
-
0038379169
-
Immunotherapy of established tumors using bone marrow transplantation with antigen gene-modified hematopoietic stem cells
-
Y. Cui, E. Kelleher, E. Straley, E. Fuchs, K. Gorski, H. Levitsky, I. Borrello, C.I. Civin, S.P. Schoenberger, and L. Cheng Immunotherapy of established tumors using bone marrow transplantation with antigen gene-modified hematopoietic stem cells Nat Med 9 2003 952 958
-
(2003)
Nat Med
, vol.9
, pp. 952-958
-
-
Cui, Y.1
Kelleher, E.2
Straley, E.3
Fuchs, E.4
Gorski, K.5
Levitsky, H.6
Borrello, I.7
Civin, C.I.8
Schoenberger, S.P.9
Cheng, L.10
-
56
-
-
0035903324
-
Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
-
R.P. Sutmuller, L.M. van Duivenvoorde, A. van Elsas, T.N. Schumacher, M.E. Wildenberg, J.P. Allison, R.E. Toes, R. Offringa, and C.J. Melief Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses J Exp Med 194 2001 823 832
-
(2001)
J Exp Med
, vol.194
, pp. 823-832
-
-
Sutmuller, R.P.1
Van Duivenvoorde, L.M.2
Van Elsas, A.3
Schumacher, T.N.4
Wildenberg, M.E.5
Allison, J.P.6
Toes, R.E.7
Offringa, R.8
Melief, C.J.9
-
57
-
-
2442484053
-
Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses
-
S. Sakaguchi Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses Annu Rev Immunol 22 2004 531 562
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
58
-
-
8544265317
-
Forkhead-box transcription factors and their role in the immune system
-
P.J. Coffer, and B.M. Burgering Forkhead-box transcription factors and their role in the immune system Nat Rev Immunol 4 2004 889 899
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 889-899
-
-
Coffer, P.J.1
Burgering, B.M.2
-
59
-
-
20044363610
-
+ T helper cells and hindered by naturally occurring T regulatory cells
-
in press.
-
+ T cells (T regulatory cells). Therefore, for an optimal tumor treatment with adoptive T cell transfer the absence of inhibitory effects of T regulatory cells is required.
-
(2005)
J Immunol
-
-
Antony, P.A.1
Piccirillo, C.A.2
Akpinarli, A.3
Finkelstein, S.E.4
Speiss, P.J.5
Surman, D.R.6
Palmer, D.C.7
Chan, C.C.8
Klebanoff, C.A.9
Overwijk, W.W.10
-
60
-
-
12744253307
-
Sinks, suppressors and antigen presenters: How lymphodepletion enhances T cell-mediated tumor immunotherapy
-
C.A. Klebanoff, H.T. Khong, P.A. Antony, D.C. Palmer, and N.P. Restifo Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy Trends Immunol 26 2005 111 117
-
(2005)
Trends Immunol
, vol.26
, pp. 111-117
-
-
Klebanoff, C.A.1
Khong, H.T.2
Antony, P.A.3
Palmer, D.C.4
Restifo, N.P.5
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