Quantification of the Aβ pepticle in Alzheimer's plaques by laser dissection microscopy combined with mass spectrometry

Journal of Mass Spectrometry

Volumn 40, Issue 2, 2005, Pages 193-201

  Rüfenacht, Pascal ^a   Güntert, Andreas ^a   Bohrmann, Bernd ^a   Ducret, Axel ^a   Döbeli, Heinz ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

A peptide; Alzheimer's disease; Laser dissection microscopy; Matrix assisted laser desorption ionization time of flight mass spectrometry

Indexed keywords

BRAIN; IONIZATION; LASER BEAM EFFECTS; MATHEMATICAL MODELS; MEDICAL PROBLEMS; NEUROLOGY; PHYSICAL CHEMISTRY; PROTEINS;

ALZHEIMER'S DISEASE (AD); LASER DESORPTION; LASER DISSECTION; PLAQUES;

MASS SPECTROMETRY;

AMYLOID BETA PROTEIN; ISOPROTEIN; ISOTOPE; NITROGEN 15; AMYLOID BETA PROTEIN (1 28); AMYLOID BETA-PROTEIN (1-28); PEPTIDE FRAGMENT;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; COGNITIVE DEFECT; DISEASE SEVERITY; HUMAN; IMMUNOBLOTTING; LASER DISSECTION MICROSCOPY; LASER MICROSCOPY; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOUSE; NONHUMAN; PATHOGENESIS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN AGGREGATION; QUANTITATIVE ANALYSIS; SENILE PLAQUE; TRANSGENE; TRANSGENIC MOUSE; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; LASER; METHODOLOGY; MICRODISSECTION; SENSITIVITY AND SPECIFICITY;

AMYLOID BETA-PROTEIN; ANIMALS; HUMANS; LASERS; MICE; MICE, TRANSGENIC; MICRODISSECTION; PEPTIDE FRAGMENTS; SENILE PLAQUES; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 14744281153     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/jms.739     Document Type: Article

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