Insights into the base catalysis exerted by the DD-transpeptidase from Streptomyces K15: A molecular dynamics study

Biochemistry

Volumn 44, Issue 9, 2005, Pages 3225-3240

  Díaz, Natalia ^a   Sordo, Tomás L ^a   Suárez, Dimas ^a  

^a UNIVERSITY OF OVIEDO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIBIOTICS; BACTERIA; CARBOXYLIC ACIDS; CATALYSIS; ENZYME INHIBITION; HYDROXYLATION; PROTEINS; SOLUTIONS;

BINDING PROTEINS; HYDROXYL GROUP; QUANTUM MECHANICAL ENERGY; RELATIVE STABILITY;

MOLECULAR DYNAMICS;

AMMONIA; BETA LACTAM ANTIBIOTIC; DD TRANSPEPTIDASE; ENZYME; HYDROXYL GROUP; K15 ENZYME; PENICILLIN BINDING PROTEIN; PENICILLIN G; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; CALCULATION; DENSITY FUNCTIONAL THEORY; ENERGY; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME STABILITY; ENZYME STRUCTURE; GEOMETRY; MICHAEL ADDITION; MOLECULAR DYNAMICS; MOLECULE; NONHUMAN; PRIORITY JOURNAL; QUANTUM MECHANICS; SIMULATION; STREPTOMYCES;

BINDING SITES; CATALYSIS; COMPUTER SIMULATION; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; ENZYME STABILITY; LYSINE; MODELS, CHEMICAL; MODELS, MOLECULAR; PENICILLIN G; PENICILLIN-BINDING PROTEINS; QUANTUM THEORY; SERINE; SERINE-TYPE D-ALA-D-ALA CARBOXYPEPTIDASE; STREPTOMYCES; THERMODYNAMICS;

EID: 14744276064     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048193g     Document Type: Article

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