Novel β-(imidazol-4-yl)-β-amino acids: Solid-phase synthesis and study of their inhibitory activity against geranylgeranyl protein transferase type I

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 6, 2005, Pages 1713-1719

  Saha, Ashis K ^a,b   End, David W ^a,c  

^a JANSSEN RESEARCH AND DEVELOPMENT   (United States)

^b Praecis Pharmaceuticals Incorporated   (United States)

^c Johnson and Johnson Pharmaceutical Research and Development LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA AMINO ACID; GERANYLTRANSFERASE; GERANYLTRANSFERASE 1; TRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ASSAY; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NUCLEAR MAGNETIC RESONANCE; SOLID PHASE SYNTHESIS;

EID: 14644388072     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.01.042     Document Type: Article

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