Novel antifungals based on 4-substituted imidazole: A combinatorial chemistry approach to lead discovery and optimization

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 19, 2000, Pages 2175-2178

  Saha, Ashis K ^a   Liu, Li ^a   Simoneaux, Richard L ^a   Kukla, Michael J ^a   Marichal, Patrick ^b   Odds, Frank ^b  

^a JANSSEN RESEARCH AND DEVELOPMENT   (United States)

^b JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

1H IMIDAZOLE 4 METHYLAMINO SULFONAMIDE; ANTIFUNGAL AGENT; FLUCONAZOLE; IMIDAZOLE DERIVATIVE; ITRACONAZOLE; SULFONAMIDE; UNCLASSIFIED DRUG; VORICONAZOLE;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

ANTIFUNGAL AGENTS; CANDIDA; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG DESIGN; ERGOSTEROL; FUNGI; IMIDAZOLES; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

CANDIDA;

EID: 0034597115     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00445-5     Document Type: Article

References (15)