Unliganded human mutant α7 nicotinic receptors are modulated by Ca2+ and trace levels of Zn2+

Neuropharmacology

Volumn 46, Issue 5, 2004, Pages 727-733

  Tonini, Raffaella ^a   Renzi, Massimiliano ^a,c   Eusebi, Fabrizio ^a,b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b Dipto di Scienze Internistiche   (Italy)

^c Città Universitaria ^*  (Italy)

Author keywords

op, mean open time; AChR, nicotinic acetylcholine receptor; Human L248T 7 mutant; L248T 7 receptors, L248T 7 neuronal nicotinic acetylcholine receptor mutant; Unliganded channels; Xenopus oocyte; Zn 2+

Indexed keywords

BUNGAROTOXIN RECEPTOR; CALCIUM ION; CATION; CHELATING AGENT; ETHYLENEDIAMINE DERIVATIVE; ION CHANNEL; METHYLLYCACONITINE; MUTANT PROTEIN; N,N,N',N' TETRAKIS 2 PYRIDYLMETHYLETHYLENEDIAMINE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; ZINC ION;

ANIMAL CELL; ARTICLE; CALCIUM CONDUCTANCE; CHANNEL GATING; CONCENTRATION (PARAMETERS); CONDUCTANCE; DOSE RESPONSE; FEMALE; MODULATION; MUTANT; NEUROMUSCULAR BLOCKING; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RECEPTOR BLOCKING; XENOPUS;

ANIMALS; CALCIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; ION CHANNEL GATING; MUTATION; RECEPTORS, NICOTINIC; XENOPUS; ZINC;

EID: 1442348870     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2003.11.001     Document Type: Article

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