Spectrin repeat proteins in the nucleus

BioEssays

Volumn 27, Issue 2, 2005, Pages 144-152

  Young, Kevin G ^b   Kothary, Rashmi ^a  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTININ; DYSTROPHIN; SPECTRIN;

AMINO ACID SEQUENCE; CELL MEMBRANE; CELL NUCLEUS MEMBRANE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CHROMATIN; CYTOPLASM; INTRACELLULAR SPACE; MOLECULAR SIZE; NUCLEOTIDE SEQUENCE; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; REVIEW;

ANIMALS; CELL MEMBRANE; CELL NUCLEUS; CHROMATIN; CYTOPLASM; EVOLUTION, MOLECULAR; FUNGAL PROTEINS; HUMANS; MODELS, BIOLOGICAL; PLANT PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SPECTRIN;

EID: 14344265557     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/bies.20177     Document Type: Review

References (91)

1. Jenkins C, Samudrala R, Anderson I, Hedlund BP, Petroni G, et al. 2002. Genes for the cytoskeletal protein tubulin in the bacterial genus Prosthecobacter. Proc Natl Acad Sci USA 99:17049-17054.
2. Doolittle RF, York AL 2002. Bacterial actins? An evolutionary perspective. BioEssays 24:293-296.
3. Daniel RA, Errington J. 2003. Control of cell morphogenesis in bacteria: two distinct ways to make a rod-shaped cell. Cell 113:767-776.
4. Pederson T. 2000. Half a century of "the nuclear matrix". Mol Biol Cell 11:799-805.
5. Rando OJ, Zhao K, Crabtree GR. 2000. Searching for a function for nuclear actin. Trends Cell Biol 10:92-97.
6. Pederson T, Aebi U. 2002. Actin in the nucleus: what form and what for? J Struct Biol 140:3-9.
7. Bettinger BT, Gilbert DM, Amberg DC. 2004. Actin up in the nucleus. Nat Rev Mol Cell Biol 5:410-415.
8. Erber A, Riemer D, Bovenschulte M, Weber K. 1998. Molecular phytogeny of metazoan intermediate filament proteins. J Mol Evol 47:751-762.
9. Holaska JM, Wilson KL, Mansharamani M. 2002. The nuclear envelope, lamins and nuclear assembly. Curr Opin Cell Biol 14:357-364.
10. Zastrow MS, Vlcek S, Wilson KL. 2004. Proteins that bind A-type lamins: integrating isolated clues. J Cell Sci 117:979-987.
11. Hutchison CJ. 2002. Lamins: building blocks or regulators of gene expression? Nat Rev Mol Cell Biol 3:848-858.
12. Andra K, Nikolic B, Stocher M, Drenckhahn D, Wiche G. 1998. Not just scaffolding: plectin regulates actin dynamics in cultured cells. Genes Dev 12:3442-3451.
13. Gregory SL, Brown NH. 1998. kakapo, a gene required for adhesion between and within cell layers in Drosophila, encodes a large cytoskeletal linker protein related to plectin and dystrophin. J Cell Biol 143: 1271-1282.
14. Dalpé G, Mathieu M, Comtois A, Zhu E, Wasiak S, et al. 1999. Dystonin-deficient mice exhibit an intrinsic muscle weakness and an instability of skeletal muscle cytoarchitecture. Dev Biol 210:367-380.
15. Norman KR, Moerman DG. 2002. Alpha spectrin is essential for morphogenesis and body wall muscle formation in Caenorhabditis elegans. J Cell Biol 157:665-677.
16. Wandersee NJ, Birkenmeier CS, Bodine DM, Mohandas N, Barker JE. 2003. Mutations in the murine erythroid alpha-spectrin gene alter spectrin mRNA and protein levels and spectrin incorporation into the red blood cell membrane skeleton. Blood 101:325-330.
17. Speicher DW, Davis G, Marchesi VT. 1983. Structure of human erythrocyte spectrin. II. The sequence of the alpha-l domain. J Biol Chem 258: 14938-14947.
18. Speicher DW, Marchesi VT. 1984. Erythrocyte spectrin is comprised of many homologous triple helical segments. Nature 311:177-180.
19. Broderick MJ, Winder SJ. 2002. Towards a complete atomic structure of spectrin family proteins. J Struct Biol 137:184-193.
20. Djinovic-Carugo K, Gautel M, Ylanne J, Young P. 2002. The spectrin repeat: a structural platform for cytoskeletal protein assemblies. FEBS Lett 513:119-123.
21. Thomas GH, Newbern EC, Korte CC, Bales MA, Muse SV, et al. 1997. Intragenic duplication and divergence in the spectrin superfamily of proteins. Mol Biol Evol 14:1285-1295.
22. Virel A, Backman L. 2004. Molecular evolution and structure of alpha-actinin. Mol Biol Evol 21:1024-1031.
23. Cianci CD, Zhang Z, Pradhan D, Morrow JS. 1999. Brain and muscle express a unique alternative transcript of alphaII spectrin. Biochemistry 38:15721-15730.
24. Harper SQ, Crawford RW, DelloRusso C, Chamberlain JS. 2002. Spectrin-like repeats from dystrophin and alpha-actinin-2 are not functionally interchangeable. Hum Mol Genet 11:1807-1815.
25. Flood G, Kahana E, Gilmore AP, Rowe AJ, Gratzer WB, et al. 1995. Association of structural repeats in the alpha-actinin rod domain. Alignment of inter-subunit interactions. J Mol Biol 252:227-234.
26. Mislow JM, Holaska JM, Kim MS, Lee KK, Segura-Totten M, et al. 2002. Nesprin-1 alpha self-associates and binds directly to emerin and lamin A in vitro. FEBS Lett 525:135-140.
27. Amann KJ, Renley BA, Ervasti JM. 1998. A cluster of basic repeats in the dystrophin rod domain binds F-actin through an electrostatic interaction. J Biol Chem 273:28419-28423.
28. Li X, Bennett V. 1996. Identification of the spectrin subunit and domains required for formation of spectrin/adducin/actin complexes. J Biol Chem 271:15695-15702.
29. Nakayama M, Kikuno R, Ohara O. 2002. Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs. Genome Res 12:1773-1784.
30. Otey CA, Pavalko FM, Burridge K. 1990. An interaction between alpha-actinin and the beta 1 integrin subunit in vitro. J Cell Biol 111:721-729.
31. Sampath R, Gallagher PJ, Pavalko FM. 1998. Cytoskeletal interactions with the leukocyte integrin beta2 cytoplasmic tail. Activation-dependent regulation of associations with talin and alpha-actinin. J Biol Chem 273: 33588-33594.
32. Xia H, Winokur ST, Kuo WL, Altherr MR, Bredt DS. 1997. Actinin-associated LIM protein: identification of a domain interaction between PDZ and spectrin-like repeat motifs. J Cell Biol 139:507-515.
33. Kapiloff MS, Schillace RV, Westphal AM, Scott JD. 1999. mAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes. J Cell Sci 112:2725-2736.
34. Tse WT, Tang J, Jin O, Korsgren C, John KM, et al. 2001. A new spectrin. beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix. J Biol Chem 276: 23974-23985.
35. Young KG, Pool M, Kothary R. 2003. Bpag1 localization to actin filaments and to the nucleus is regulated by its N-terminus. J Cell Sci 116:4543-4555.
36. Hiller G, Weber K. 1977. Spectrin is absent in various tissue culture cells. Nature 266:181-183.
37. Levine J, Willard M. 1981. Fodrin: axonally transported polypeptides associated with the internal periphery of many cells. J Cell Biol 90:631-642.
38. Burridge K, Kelly T, Mangeat P. 1982. Nonerythrocyte spectrins: actin-membrane attachment proteins occurring in many cell types. J Cell Biol 95:478-486.
39. Bachs O, Lanini L, Serratosa J, Coll MJ, Bastos R, et al. 1990. Calmodulin-binding proteins in the nuclei of quiescent and proliferatively activated rat liver cells. J Biol Chem 265:18595-18600.
40. Vendrell M, Aligue R, Bachs O, Seratosa J. 1991. Presence of calmodulin and calmodulin-binding proteins in the nuclei of brain cells. J Neurochem 57:622-628.
41. McMahon LW, Walsh CE, Lambert MW. 1999. Human alpha spectrin II and the Fanconi anemia proteins FANCA and FANCC interact to form a nuclear complex. J Biol Chem 274:32904-32908.
42. McMahon LW, Sangerman J, Goodman SR, Kumaresan K, Lambert MW. 2001. Human alpha spectrin II and the FANCA, FANCC, and FANCG proteins bind to DNA containing psoralen interstrand cross-links. Biochemistry 40:7025-7034.
43. Sridharan D, Brown M, Lambert WC, McMahon LW, Lambert MW. 2003. Nonerythroid alphaII spectrin is required for recruitment of FANCA and XPF to nuclear foci induced by DNA interstrand cross-links. J Cell Sci 116:823-835.
44. Borden KL. 2002. Pondering the promyelocytic leukemia protein (PML) puzzle: possible functions for PML nuclear bodies. Mol Cell Biol 22: 5259-5269.
45. Tang Y, Katuri V, Dillner A, Mishra B, Deng CX, et al. 2003. Disruption of transforming growth factor-beta signaling in ELF beta-spectrin-deficient mice. Science 299:574-577.
46. Apel ED, Lewis RM, Grady RM, Sanes JR. 2000. Syne-1, a dystrophin-and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction. J Biol Chem 275:31986-31995.
47. Zhang Q, Skepper JN, Yang F, Davies JD, Hegyi L, et al. 2001. Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues. J Cell Sci 114:4485-4498.
48. Zhen YY, Libotte T, Munck M, Noegel AA, Korenbaum E. 2002. NUANCE, a giant protein connecting the nucleus and actin cytoskeleton. J Cell Sci 115:3207-3222.
49. Mislow JM, Kim MS, Davis DB, McNally EM. 2002. Myne-1, a spectrin repeat transmembrane protein of the myocyte inner nuclear membrane, interacts with lamin A/C. J Cell Sci 115:61-70.
50. Padmakumar VC, Abraham S, Braune S, Noegel AA, Tunggal B, et al. 2004. Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeleton. Exp Cell Res 295:330-339.
51. Starr DA, Han M. 2003. ANChors away: an actin based mechanism of nuclear positioning. J Cell Sci 116:211-216.
52. Fan J, Beck KA. 2004. A role for the spectrin superfamily member Syne-1 and kinesin Ii in cytokinesis. J Cell Sci 117:619-629.
53. Kapiloff MS, Jackson N, Airhart N. 2001. mAKAP and the ryanodine receptor are part of a multi-component signaling complex on the cardiomyocyte nuclear envelope. J Cell Sci 114:3167-3176.
54. Harley VR, Layfield S, Mitchell CL, Forwood JK, John AP, et al. 2003. Defective importin beta recognition and nuclear import of the sex-determining factor SRY are associated with XY sex-reversing mutations. Proc Natl Acad Sci USA 100:7045-7050.
55. Jakel S, Gorlich D. 1998. Importin beta, transportin, RanBPS and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells. EMBO J 17:4491-4502.
56. Lam MH, Briggs LJ, Hu W, Martin TJ, Gillespie MT, et al. 1999. Importin beta recognizes parathyroid hormone-related protein with high affinity and mediates its nuclear import in the absence of importin alpha. J Biol Chem 274:7391-7398.
57. Moore JD, Yang J, Truant R, Kornbluth S. 1999. Nuclear import of Cdk/cyclin complexes: identification of distinct mechanisms for import of Cdk2/cyclin E and Cdc2/cyclin B1. J Cell Biol 144:213-224.
58. Xiao Z, Liu X, Lodish HF. 2000. Importin beta mediates nuclear translocation of Smad 3. J Biol Chem 275:23425-23428.
59. Cokol M, Nair R, Rost B. 2000. Finding nuclear localization signals. EMBO Rep 1:411-415.
60. Jones G, Stewart G. 2004. Nuclear import of N-terminal FAK by activation of the FcepsilonRI receptor in RBL-2H3 cells. Biochem Biophys Res Commun 314:39-45.
61. Lobo M, Zachary I. 2000. Nuclear localization and apoptotic regulation of an amino-terminal domain focal adhesion kinase fragment in endothelial cells. Biochem Biophys Res Commun 276:1068-1074.
62. Loy CJ, Sim KS, Yong EL. 2003. Filamin-A fragment localizes to the nucleus to regulate androgen receptor and coactivator functions. Proc Natl Acad Sci USA 100:4562-4567.
63. De Ruijter NC, Emons AM. 1993. Immunodetection of spectrin antigens in plant cells. Cell Biol Int 17:169-182.
64. De Ruijter NC, Ketelaar T, Blumenthal SS, Emons AM, Schel JH. 2000. Spectrin-like proteins in plant nuclei. Cell Biol Int 24:427-438.
65. Slaninova I, Holubarova A, Svoboda A. 2003. Immunodetection of spectrin-like proteins in yeasts. Can J Microbiol 49:189-196.
66. Slesarev AI, Mezhevaya KV, Makarova KS, Polushin NN, Shcherbinina OV, et al. 2002. The complete genome of hyperthermophile Methanopyrus kandleri AV19 and monophyly of archaeal methanogens. Proc Natl Acad Sci USA 99:4644-4649.
67. Honda K, Yamada T, Endo R, Ino Y, Gotoh M, et al. 1998. Actinin-4, a novel actin-bundling protein associated with cell motility and cancer invasion. J Cell Biol 140:1383-1393.
68. Fay FS, Taneja KL, Shenoy S, Lifshitz L, Singer RH. 1997. Quantitative digital analysis of diffuse and concentrated nuclear distributions of nascent transcripts, SC35 and poly(A). Exp Cell Res 231:27-37.
69. Lallena MJ, Martinez C, Valcarcel J, Correas I. 1998. Functional association of nuclear protein 4.1 with pre-mRNA splicing factors. J Cell Sci 111:1963-1971.
70. Zeng C, He D, Berget SM, Brinkley BR. 1994. Nuclear-mitotic apparatus protein: a structural protein interface between the nucleoskeleton and RNA splicing. Proc Natl Acad Sci USA 91:1505-1509.
71. Harborth J, Wang J, Gueth-Hallonet C, Weber K, Osborn M. 1999. Self assembly of NuMA: multiarm oligomers as structural units of a nuclear lattice. EMBO J 18:1689-1700.
72. Levesque AA, Howard L, Gordon MB, Compton DA. 2003. A functional relationship between NuMA and kid is involved in both spindle organization and chromosome alignment in vertebrate cells. Mol Biol Cell 14:3541-3552.
73. Yang CH, Lambie EJ, Snyder M. 1992. NuMA: an unusually long coiled-coil related protein in the mammalian nucleus. J Cell Biol 116:1303-1317.
74. Novatchkova M, Eisenhaber F. 2002. A CH domain-containing N terminus in NuMA? Protein Sci 11:2281-2284.
75. Haren L, Merdes A. 2002. Direct binding of NuMA to tubulin is mediated by a novel sequence motif in the tail domain that bundles and stabilizes microtubules. J Cell Sci 115:1815-1824.
76. Starr DA, Han M. 2002. Role of ANC-1 in tethering nuclei to the actin cytoskeleton. Science 298:406-409.
77. Gascard P, Nunomura W, Lee G, Walensky LD, Krauss SW, et al. 1999. Deciphering the nuclear import pathway for the cytoskeletal red cell protein 4.1R. Mol Biol Cell 10:1783-1798.
78. Mattagajasingh SN, Huang SC, Hartenstein JS, Snyder M, Marchesi VT, et al. 1999. A nonerythroid isoform of protein 4.1R interacts with the nuclear mitotic apparatus (NuMA) protein. J Cell Biol 145:29-43.
79. Luque CM, Correas I. 2000. A constitutive region is responsible for nuclear targeting of 4.1 R: modulation by alternative sequences results in differential intracellular localization. J Cell Sci 113:2485-2495.
80. Krauss SW, Chen C, Penman S, Heald R. 2003. Nuclear actin and protein 4.1: essential interactions during nuclear assembly in vitro. Proc Natl Acad Sci USA 100:10752-10757.
81. Krauss SW, Heald R, Lee G, Nunomura W, Gimm JA, et al. 2002. Two distinct domains of protein 4.1 critical for assembly of functional nuclei in vitro. J Biol Chem 277:44339-44346.
82. Gonsior SM, Platz S, Buchmeier S, Scheer U, Jockusch BM, et al. 1999. Conformational difference between nuclear and cytoplasmic actin as detected by a monoclonal antibody. J Cell Sci 112:797-809.
83. Orlova A, Rybakova IN, Prochniewicz E, Thomas DD, Ervasti JM, et al. 2001. Binding of dystrophin's tandem calponin homology domain to F-actin is modulated by actin's structure. Biophys J 80: 1926-1931.
84. Carotenuto R, Maturi G, Infante V, Capriglione T, Petrucci TC, et al. 1997. A novel protein cross-reacting with antibodies against spectrin is localized in the nucleoli of amphibian oocytes. J Cell Sci 110:2683-2690.
85. Carmo-Fonseca M. 2002. The contribution of nuclear compartmentalization to gene regulation. Cell 108:513-521.
86. Chubb JR, Bickmore WA. 2003. Considering nuclear compartmentalization in the light of nuclear dynamics. Cell 112:403-406.
87. Palstra RJ, Tolhuis B, Splinter E, Nijmeijer R, Grosveld F, et al. 2003. The beta-globin nuclear compartment in development and erythroid differentiation. Nat Genet 35:190-194.
88. Bernier G, De Repentigny Y, Mathieu M, David S, Kothary R. 1998. Dystonin is an essential component of the Schwann cell cytoskeleton at the time of myelination. Development 125:2135-2148.
89. Dalpé G, Leclerc N, Vallée A, Messer A, Mathieu M, et al. 1998. Dystonin is essential for maintaining neuronal cytoskeleton organization. Mol Cell Neurosci 10:243-257.
90. Komada M, Soriano P. 2002. [Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier. J Cell Biol 156:337-348.
91. Koradi R, Billeter M, Wüthrich K. 1996. MOLMOL: a program for display and analysis of macromolecular structures. J Mol Graphics 14:51-55.