Not just scaffolding: Plectin regulates actin dynamics in cultured cells

Genes and Development

Volumn 12, Issue 21, 1998, Pages 3442-3451

  Andrä, Kerstin ^a   Nikolic, Branislav ^a   Stöcher, Markus ^a   Drenckhahn, Detlev ^b   Wiche, Gerhard ^a  

^a Vienna Biocenter   (Austria)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Actin dynamics; Cytoskeleton; Fibroblasts; Plectin; Rho Rac Cdc42

Indexed keywords

ACTIN; CELL ADHESION MOLECULE;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL MIGRATION; CELL MOTILITY; CYTOSKELETON; GENETIC TRANSFECTION; INTERMEDIATE FILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN SYNTHESIS REGULATION; SHEAR STRESS; SKIN FIBROBLAST;

ANIMALIA; GOES;

EID: 0032213892     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.12.21.3442     Document Type: Article

References (46)

1. Andrä, K., H. Lassmann, R. Bittner, S. Shorny, R. Fässler, F. Propst, and G. Wiche. 1997. Targeted inactivation of plectin reveals essential function in maintaining integrity of skin, muscle, and heart cytoarchitecture. Genes & Dev. 11: 3143-3156.
2. Bershadsky, A., A. Chausovsky, E. Becker, A. Lyubimova, and B. Geiger. 1996. Involvement of microtubules in the control of adhesion-dependent signal transduction. Curr. Biol. 6: 1279-1289.
3. Chavanas, S., L. Pulkkinen, Y. Gache, F.J.D. Smith, W.H.I. McLean, J. Uitto, J.P. Ortonne, and G. Meneguzzi. 1996. A homozygous nonsense mutation in the PLEC1 gene in patients with epidermolysis bullosa simplex with muscular dystrophy. J. Clin. Invest. 98: 2196-2200.
4. Cunningham, C.C., T.P. Stossel, and D.J. Kwiatkowski. 1991. Enhanced motility in NIH 3T3 fibroblasts that overexpress gelsolin. Science 251: 1233-1236.
5. Cunningham, C.C, J.B. Gorlin, D.J. Kwiatkowski, J.H. Hartwig, P.A. Janmey, H.R. Byers, and T.P. Stossel. 1992. Actin-binding protein requirement for cortical stability and efficient locomotion. Science 255: 325-327.
6. Eger, A., A. Stockinger, G. Wiche, and R. Foisner. 1997. Polarization dependent association of plectin with desmoplakin at the lateral submembrane skeleton in MDCK cells. J. Cell Sci. 110: 1307-1316.
7. Elliott, C.E., B. Becker, S. Oehler, M.J. Castañón, R. Hauptmann, and G. Wiche. 1997. Plectin gene transcription diversity: Multiple alternative first exons, rod-less and other isoforms. Genomics 42: 115-125.
8. Errante, L.D., G. Wiche, and G. Shaw. 1994. Distribution of plectin, an intermediate filament-associated protein, in the adult rat central nervous system. J. Neurosci. Res. 37: 515-528.
9. Foisner, R., F.E. Leichtfried, H. Herrmann, J.V. Small, D. Lawson, and G. Wiche. 1988. Cytoskeleton-associated plectin: In situ localization, in vitro reconstitution, and binding to immobilized filament proteins. J. Cell Biol. 106: 723-733.
10. Foisner, R., W. Bohn, K. Mannweiler, and G. Wiche. 1995. Distribution and ultrastructure of plectin arrays in subclones of rat glioma C6 cells differing in intermediate filament protein (vimentin) expression. J. Struct. Biol. 115: 304-317.
11. Cache, Y., S. Chavanas, J.P. Lacour, G. Wiche, K. Owaribe, G. Meneguzzi, and J.P. Ortonne. 1996. Defective expression of plectin/HD1 in epidermolysis bullosa simplex with muscular dystrophy. J. Clin. Invest. 97: 2289-2298.
12. Gilmore, A.P. and K. Burridge. 1996. Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-biphosphate. Nature 381: 531-535.
13. Hall, A. 1998. Rho GTPases and the actin cytoskeleton. Science 279: 509-514.
14. Hao, C., A. Richardson, and S. Fedoroff. 1992. Isolation of microglia from mouse astroglia cultures. In Protocols for neural cell culture (ed. S. Fedoroff and A. Richardson), pp. 97-104. Humana Press, Totowa, NJ.
15. Hartwig, J.H., G.M. Bokoch, C.L. Carpenter, P.A. Janmey, L.A. Taylor, A. Toker, and T.P. Stossel. Thrombin receptor ligation and activated Rac uncap actin filament barbeolenol through phosphoinositide synthesis in permeabilized human platelets. 1995. Cell 82: 643-653.
16. Haus, U., H. Hartmann, P. Trommler, A.A. Noegel, and M. Schleicher. 1991. F-actin capping by cap32/34 requires heterodimeric conformation and can be inhibited with PIP2. Biochem. Biophys. Res. Commun. 181: 833-839.
17. Herrmann, H. and G. Wiche. 1987. Plectin and IFAP-300k are homologous proteins binding to microtubules-associated proteins 1 and 2 and to the 240-kilodalton subunit of spectrin. J. Biol. Chem. 262: 1320-1325.
18. Hoffmann, A., L. Eichinger, E. Andre, D. Rieger, and M. Schleicher. 1992. Cap100, a novel phosphatidylinositol 4,5-biphosphate-regulated protein that caps actin filaments but does not nucleate actin assembly. Cell Motil. Cytoskelet. 23: 133-144.
19. Hug, C., P.Y. Jay, I. Reddy, J.G. McNally, P.C. Bridgman, E.L. Elson, and J.A. Cooper. 1995. Capping protein levels influence actin assembly and cell motility in dictyostelium. Cell 81: 591-600.
20. Ilic, D., Y. Furuta, S. Kanazawa, N. Takeda, K. Sobue, N. Nakatsuji, S. Nomura, J. Fujimoto, M. Okada, T. Yamamoto, and S. Aizawa. 1995. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Science 377: 539-543.
21. Janmey, P.A. 1994. Phosphoinositides and calcium as regulators of cellular actin assembly and disassembly. Annu. Rev. Physiol. 56: 169-191.
22. Jones, G.E. 1996. Establishment, maintenance, and cloning of human primary cell strains. In Methods in molecular medicine (ed. G.E. Jones), pp. 15-18. Humana Press, Totowa, NJ.
23. Koslow, A.R., R.R. Stromberg, L.I. Friedman, R.J. Lutz, S.L. Hilbert, and P. Schuster. 1986. A flow system for the study of shear forces upon cultured endothelial cells. J. Biomech. Eng. 108: 338-341.
24. Koyama, Y., T. Fukuda, and A. Baba. 1996. Inhibition of vanadate-induced astrocytic stress fiber formation by C3 ADP-ribosyltransferase. Biochem. Biophys. Res. Commun. 218: 331-336.
25. Lassing, I. and U. Lindberg. 1985. Specific interaction between phosphatidyl-inositol 4,5-biphosphate and profilactin. Nature 314: 472-474.
26. _. 1988. Specificity of the interaction between phosphatidylinositol 4,5-biphosphate and the profilin: Actin complex. J. Cell Biochem. 37: 255-267.
27. Liu, C.-G., C. Maercker, M.J. Castañón, R. Hauptmann, and G. Wiche. 1996. Human plectin: Organization of the gene, sequence analysis, and chromosome localization (8q24). Proc. Natl. Acad. Sci. 93: 4278-4283.
28. Lo, S.H., P.A. Janmey, J.H. Hartwig, and L.B. Chen. 1994. Interactions of tensin with actin and identification of its three distinct actin-binding domains. J. Cell Biol. 125: 1067-1075.
29. McLean, W.H.I., L. Pulkkinen, F.D.J. Smith, E.L. Rugg, E.B. Lane, F. Bullrich, R.E. Burgeson, S. Armano, D.L. Hudson, K. Owaribe, J.A. McGrath, J.R. McMillan, R.A.J. Eady, I.M. Leigh, A.M. Christiano, and J. Uitto. 1996. Loss of plectin causes epidermolysis bullosa with muscle dystrophy: cDNA cloning and genomic organization. Genes & Dev. 10: 1724-1735.
30. Mellerio, J.E, F.J.D. Smith, J.R. McMillan, W.H.I. McLean, J.A. McGrath, G.A.J. Morrison, P. Tierny, D.M. Albert, G. Wiche, I.M. Leigh, J.F. Geddes, E.B. Lane, J. Uitto, and R.A.J. Eady. 1997. Recessive epidermolysis bullosa simplex associated with plectin mutations: Infantile respiratory complications in two unrelated cases. Br. J. Dermatol. 137: 989-996.
31. Nikolic, B., E. Mac Nulty, B. Mir, and G. Wiche. 1996. Basic amino acid residue cluster within nuclear targeting sequence motif is essential for cytoplasmic plectin-vimentin network junctions. J. Cell Biol. 134: 1455-1467.
32. Pulkkinen, L., F.J.D. Smith, H. Shimizu, S. Murata, H. Yaoita, H. Hachisuka, T. Nishikawa, W.H.I. McLean, and J. Uitto. 1996. Homozygous deletion mutations in the plectin gene (PLEC1) in patients with epidermolysis bullosa simplex associated with late-onset muscular dystrophy. Hum. Mol. Genet. 5: 1539-1546.
33. Rezniczek, G.A., J.M. de Pereda, S. Reipert, and G. Wiche. 1998. Linking integrin α6/β4-based cell adhesion to the intermediate filament cytoskeleton: Direct interaction between the β4 subunit and plectin at multiple molecular sites. J. Cell Biol. 141: 209-225.
34. Sarria, A.J., J.G. Lieber, S.K. Nordeen, and R.M. Evans. 1994. The presence or absence of a vimentin-type intermediate filament network affects the shape of the nucleus in human SW-13 cells. J. Cell Sci. 107: 1593-1607.
35. Seifert, G.J., D. Lawson, and G. Wiche. 1992. Immunolocalization of the intermediate filament-associated protein plectin at focal contacts and actin stress fibers. Eur. J. Cell Biol. 59: 138-147.
36. Smith, F.J.D., R.A.J. Eady, I.M. Leigh, J.R. McMillan, E.L. Rugg, D.P. Kelsell, S.P. Bryant, N.K. Spurr, J.F. Geddes, G. Kirtschig, G. Milana, A.G. de Bono, K. Owaribe, G. Wiche, L. Pulkkinen, J. Uitto, W.H.I. McLean, and E.B. Lane. 1996. Plectin deficiency results in muscular dystrophy with epidermolysis bullosa. Nat. Genet. 13: 450-457.
37. Sun, H.Q., K. Kwiatkowska, D.C. Wooten, and H.L. Yin. 1995. Effects of CapG overexpression on agonist-induced motility and second messenger generation. J. Cell Biol. 129: 147-156.
38. Svitkina, T.M., A.B. Verkhovsky, and G.G. Borisy. 1996. Plectin sidearms mediate interactions of intermediate filaments with microtubules and other components of the cytoskeleton. J. Cell Biol. 135: 991-1007.
39. Wiche, G. and M.A. Baker. 1982. Cytoplasmic network arrays demonstrated by immunolocalization using antibodies to a high molecular weight protein present in cytoskeletal preparations from cultured cells. Exp. Cell Res. 138: 15-29.
40. Wiche, G., R. Krepler, U. Artlieb, R. Pytela, and H. Denk. 1983. Occurrence and immunolocalization of plectin in tissues. J. Cell Biol. 97: 887-901.
41. Wiche, G., R. Krepler, U. Artlieb, R. Pytela, and W. Aberer. 1984. Identification of plectin in different human cell types and immunolocalization at epithelial basal cell surface membranes. Exp. Cell Res. 155: 43-49.
42. Wiche, G., D. Gromov, A. Donovan, M.J. Castañón, and E. Fuchs. 1993. Expression of plectin mutant cDNA in cultured cells indicates a role of C-terminal domain in intermediate filament association. J. Cell Biol. 121: 607-619.
43. Witke, W., A.H. Sharpe, J.H. Hartwig, T. Azuma, T.P. Stossel, and D.J. Kwiatkowski. 1995. Hemostatic, inflammatory, and fibroblast response are blunted in mice lacking gelsolin. Cell 81: 41-51.
44. Yamada, K.M. and B. Geiger. 1997. Molecular interactions in cell adhesion complexes. Curr. Opin. Cell Biol. 9: 76-85.
45. Yang, Y., J. Dowling, Q.C. Yu, P. Kouklis, D.W. Cleveland, and E. Fuchs. 1996. An essential cytoskeletal linker protein connecting actin microfilaments to intermediate filaments. Cell 86: 655-665.
46. Yoshimura, S., H. Sakai, S. Nakashima, Y. Nozawa, J. Shinoda, N. Sakai, and H. Yamada. 1997. Differential expression of Rho family GTP-binding proteins and protein kinase C isozymes during C6 glial cell differentiation. Brain Res. Mol. Brain Res. 45: 90-98.