A network of conserved intramolecular contacts defines the off-state of the transmembrane switch mechanism in a seven-transmembrane receptor

Journal of Biological Chemistry

Volumn 275, Issue 8, 2000, Pages 5682-5686

  Lu, Zhi Liang ^a   Hulme, Edward C ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; GUANINE NUCLEOTIDE BINDING PROTEIN; HISTIDINE; MEMBRANE RECEPTOR; MUSCARINIC RECEPTOR; RHODOPSIN; ZINC ION;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; MOLECULAR INTERACTION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN STRUCTURE; SEQUENCE ANALYSIS;

ACETYLCHOLINE; ANIMALS; BINDING SITES; COS CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTIDINE; KINETICS; LIGANDS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MUSCARINIC ANTAGONISTS; MUTAGENESIS, SITE-DIRECTED; PHOSPHATIDYLINOSITOLS; POLYMERASE CHAIN REACTION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, CELL SURFACE; RECEPTORS, MUSCARINIC; TRANSFECTION; ZINC;

EID: 0034095059     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.8.5682     Document Type: Article

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