A refined model of the thyrotropin-releasing hormone (TRH) receptor binding pocket. Experimental analysis and energy minimization of the complex between TRH and TRH receptor

Biochemistry

Volumn 35, Issue 24, 1996, Pages 7643-7650

  Perlman, Jeffrey H ^a   Laakkonen, Liisa J ^b   Guarnieri, Frank ^b   Osman, Roman ^b   Gershengorn, Marvin C ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; ARGININE; GLYCOPROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; HISTIDINE; LIGAND; PROTIRELIN; PROTIRELIN DERIVATIVE; PROTIRELIN RECEPTOR; TYROSINE;

ANIMAL CELL; ARTICLE; DISSOCIATION CONSTANT; ENERGY; HORMONE RECEPTOR INTERACTION; MODEL; MONKEY; NONHUMAN; PRIORITY JOURNAL; SIMULATION; SYSTEM ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CERCOPITHECUS AETHIOPS; KIDNEY; KINETICS; MATHEMATICS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MONTE CARLO METHOD; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; POLYMERASE CHAIN REACTION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, THYROTROPIN-RELEASING HORMONE; RECOMBINANT PROTEINS; STOCHASTIC PROCESSES; THYROTROPIN-RELEASING HORMONE; TRANSFECTION;

ANIMALIA;

EID: 0029953735     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952202r     Document Type: Article

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