Molecular mechanism of cell death induced by the antioxidant tert-butylhydroxyanisole in human monocytic leukemia U937 cells

Biological and Pharmaceutical Bulletin

Volumn 27, Issue 3, 2004, Pages 295-302

  Okubo, Tomoko ^a   Yokoyama, Yoshiko ^b   Kano, Kazutaka ^b   Kano, Itsu ^a  

^a TOKYO METROPOLITAN INSTITUTE OF PUBLIC HEALTH   (Japan)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; Caspase; DNA ladder; Mitochondrial transmembrane potential; Oxidative phosphorylation; tert butylhydroxyanisole

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIOXIDANT; BUTYLATED HYDROXYANISOLE; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; CYTOCHROME C OXIDASE; CYTOCHROME C3; GLUCOSE; GLUTATHIONE; MITOCHONDRIAL ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); 3-TERT-BUTYL-4-HYDROXYANISOLE; CASPASE; CYTOCHROME C;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL LYSATE; CELL STRAIN U937; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; DNA CLEAVAGE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME MECHANISM; HUMAN; HUMAN CELL; LEUKEMIA CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; NUCLEOSOME; OXIDATIVE PHOSPHORYLATION; REDUCTION; RESPIRATORY CHAIN; CELL DEATH; CELL MEMBRANE POTENTIAL; COMPARATIVE STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; FLOW CYTOMETRY; METABOLISM; MITOCHONDRION; PHYSIOLOGY; TIME; WESTERN BLOTTING;

ANTIOXIDANTS; BLOTTING, WESTERN; BUTYLATED HYDROXYANISOLE; CASPASES; CELL DEATH; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX II; ELECTRON TRANSPORT COMPLEX IV; FLOW CYTOMETRY; GLUTATHIONE; HUMANS; MEMBRANE POTENTIALS; MITOCHONDRIA; OXIDATIVE PHOSPHORYLATION; TIME FACTORS; U937 CELLS;

EID: 13844260816     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.27.295     Document Type: Article

References (39)

1. Ishiwata H., Fukushima A., Abe Y., Yamada T., Nishijima M., Fukasawa Y., J. Food Hyg. Soc. Japan, 41, 86-93 (2000).
2. Van Dokkum W., De Vos R. H., Cloughley F. A., Hulshol K. F., Dukel F., Wijsman J. A., Br. J. Nutr., 48, 223-231 (1982).
3. Leclercq C., Arcella D., Turrini A., Food Chem. Toxicol., 38, 1075-1084 (2000).
4. Maziero G. C., Baunwart C., Toledo M. C., Food Addit. Contam., 18, 365-373 (2001).
5. Conacher H. B. S., Iverson F., Lau P.-Y., Page B. D., Food Chem. Toxicol., 24, 1159-1162 (1986).
6. Reddy B. S., Maeura Y., J. Natl. Cancer Inst., 72, 1181-1187 (1984).
7. Horváthová E., Slameňová D., Bonatti S., Abbondandolo A., Neoplasma, 46, 356-362 (1999).
8. Lin Y. S., Kuo H. L., Kuo C. F., Wang S. T., Yang B. C., Chen H. I., Med. Sci. Sports Exerc., 31, 1594-1598 (1999).
9. Brekke O.-L., Shalaby M. R., Sundan A., Espevik T., Bjerve K. S., Cytokine, 4, 269-280 (1992).
10. Vercammen D., Beyaert R., Denecker G., Goossens V., Loo G. V., Declercq W., Grooten J., Fiers W., Vandenabeele P., J. Exp. Med., 187, 1477-1485 (1998).
11. Ratan R. R., Murphy T. H., Baraban J. M., J. Neurochem., 62, 376-379 (1994).
12. Verhaegen S., McGowan A. J., Brophy A. R., Fernandes R. S., Cotter T. G., Biochem. Pharmacol., 50, 1021-1029 (1995).
13. Hayashi T., Catanzaro A., Rao S. P., Infect. Immun., 65, 5262-5271 (1997).
14. Ito N., Fukushima S., Hagiwara A., Shibata M., Ogiso T., J. Natl. Cancer Inst., 70, 343-352 (1983).
15. Ito N., Fukushima S., Imaida K., Sakata T., Masui T., Gann, 74, 459-461 (1983).
16. Kirlin W. G., Cai J., DeLong M. J., Patten E. J., Jones D. P., J. Nutr., 129, 1827-1835 (1999).
17. Babich H., Borenfreund E., J. Pharm. Sci., 79, 592-594 (1990).
18. Yu R., Mandlekar S., Kong A. T., Mol. Pharmacol., 58, 431-437 (2000).
19. Fusi F., Sgaragli G., Murphy M. P., Biochem. Pharmacol., 43, 1203-1208 (1992).
20. Thompson D., Moldéus P., Biochem. Pharmacol., 37, 2201-2207 (1988).
21. Yokoyama Y., Okubo T., Ozawa S., Nagai F., Ushiyama K., Kano I., Shioda M., Kubo H., Takemura M., Namiki H., Yasugi E., Oshima M., Seyama Y., Kano K., FEBS Lett., 412, 153-156 (1997).
22. Troyano A., Fernandez C., Sancho P., de Blas E., Aller P., J. Biol. Chem., 276, 47107-47115 (2001).
23. Salvioli S., Ardizzoni A., Franceschi C., Cossarizza A., FEBS Lett., 411, 77-82 (1997).
24. Shah G. M., Shah R. G., Poirier G. G., Biochem. Biophys. Res. Commun., 229, 838-844 (1996).
25. Hissin P. J., Hilf R., Anal. Biochem., 74, 214-226 (1976).
26. Cornelissen J., Wanders R. J., Van Gennip A. H., Van den Bogert C., Voûte P. A., Van Kuilenburg A. B., Biochem. Pharmacol., 49, 471-477 (1995).
27. Trounce I. A., Kim Y. L., Jun A. S., Wallace D. C., Methods Enzymol., 264, 484-509 (1996).
28. Cardoso S. M., Pereira C., Oliveira R., Free Radic. Biol. Med., 26, 3-13 (1999).
29. Kroemer G., Dallaporta B., Resche-Rigon M., Annu. Rev. Physiol., 60, 619-642 (1998).
30. Cryns V., Yuan J., Genes Dev., 12, 1551-1570 (1998).
31. Thornberry N. A., Lazebnik Y., Science, 281, 1312-1316 (1998).
32. Fones E., Amigo H., Gallegos K., Guerrero A., Ferreira J., Biochem. Pharmacol., 38, 3443-3451 (1989).
33. Ferreira J., Biochem. Pharmacol., 40, 677-684 (1990).
34. Alleva R., Tomasetti M., Andera L., Gellert N., Borghi B., Weber C., Murphy M. P., Neuzil J., FEBS Lett., 503, 46-50 (2001).
35. Merad-Boudia M., Nicole A., Santiard-Baron D., Saillé C., Ceballos-Picot I., Biochem. Pharmacol., 56, 645-655 (1998).
36. Visarius T. M., Putt D. A., Schare J. M., Pegouske D. M., Lash L. H., Biochem. Pharmacol., 52, 259-272 (1996).
37. Lash L. H., Putt D. A., Biochem. Pharmacol., 58, 897-907 (1999).
38. Leist M., Single B., Castoldi A. F., Kühnle S. K., Nicotera P., J. Exp. Med., 185, 1481-1486 (1997).
39. Lieberthal W., Menza S. A., Levine J. S., Am. J. Physiol., 274, F315-F327 (1998).