메뉴 건너뛰기




Volumn 58, Issue 2, 2000, Pages 431-437

Molecular mechanisms of butylated hydroxylanisole-induced toxicity: Induction of apoptosis through direct release of cytochrome c

Author keywords

[No Author keywords available]

Indexed keywords

ANISOLE DERIVATIVE; CYTOCHROME C OXIDASE;

EID: 0033943875     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.58.2.431     Document Type: Article
Times cited : (78)

References (37)
  • 1
    • 0031044652 scopus 로고    scopus 로고
    • Mammalian cell death proteases: A family of highly conserved aspartate specific cysteine proteases
    • Alnemri ES (1997) Mammalian cell death proteases: A family of highly conserved aspartate specific cysteine proteases. J Cell Biochem 64:33-42.
    • (1997) J Cell Biochem , vol.64 , pp. 33-42
    • Alnemri, E.S.1
  • 2
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi A and Dixit VM (1998) Death receptors: Signaling and Modulation. Science (Wash DC) 281:1305-1308.
    • (1998) Science (Wash DC) , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 4
    • 0019142866 scopus 로고
    • Increase of NAD(P)H:Quinone reductase by dietary antioxidants: Possible role in protection against carcinogenesis and toxicity
    • Benson AM, Hunkeler MJ and Talalay P (1980) Increase of NAD(P)H:quinone reductase by dietary antioxidants: Possible role in protection against carcinogenesis and toxicity. Proc Natl Acad Sci USA 77:5216-5220.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 5216-5220
    • Benson, A.M.1    Hunkeler, M.J.2    Talalay, P.3
  • 5
    • 0029863399 scopus 로고    scopus 로고
    • Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites
    • Costantini P, Chernyak BV, Petronilli V and Bernardi P (1996) Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites. J Biol Chem 271:6746-6751.
    • (1996) J Biol Chem , vol.271 , pp. 6746-6751
    • Costantini, P.1    Chernyak, B.V.2    Petronilli, V.3    Bernardi, P.4
  • 6
    • 0021112677 scopus 로고
    • Butylated hydroxyanisole-stimulated NADPH-oxidase activity in rat microsomal fractions
    • Cummings SW and Prough RA (1983) Butylated hydroxyanisole-stimulated NADPH-oxidase activity in rat microsomal fractions. J Biol Chem 258:12315-12319.
    • (1983) J Biol Chem , vol.258 , pp. 12315-12319
    • Cummings, S.W.1    Prough, R.A.2
  • 7
    • 0015971310 scopus 로고
    • Perturbation of the dynamics of lipid alkyl chains in membrane systems: Effect on the activity of membrane-bound enzymes
    • Eletr S, Williams MA, Watkins T and Keith AD (1974) Perturbation of the dynamics of lipid alkyl chains in membrane systems: Effect on the activity of membrane-bound enzymes. Biochim Blophys Acta 339:190-201.
    • (1974) Biochim Blophys Acta , vol.339 , pp. 190-201
    • Eletr, S.1    Williams, M.A.2    Watkins, T.3    Keith, A.D.4
  • 9
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green DR and Reed JC (1998) Mitochondria and apoptosis. Science (Wash DC) 281:1309-1312.
    • (1998) Science (Wash DC) , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 11
    • 0033569714 scopus 로고    scopus 로고
    • Cytochrome c-mediated apoptosis in cells lacking mitochondrial DNA. Signaling pathway involving release and caspase 3 activation is conserved
    • Jiang S, Cai J, Wallace DC and Jones DP (1999) cytochrome c-mediated apoptosis in cells lacking mitochondrial DNA. Signaling pathway involving release and caspase 3 activation is conserved. J Biol Chem 274:29905-29911.
    • (1999) J Biol Chem , vol.274 , pp. 29905-29911
    • Jiang, S.1    Cai, J.2    Wallace, D.C.3    Jones, D.P.4
  • 12
    • 0021720451 scopus 로고
    • Synthetic antioxidants: Biochemical action and interference with radiation, toxic compounds, chemical mutagens and chemical carcinogens
    • Kahl R (1984) Synthetic antioxidants: Biochemical action and interference with radiation, toxic compounds, chemical mutagens and chemical carcinogens. Toxicology 33:185-228.
    • (1984) Toxicology , vol.33 , pp. 185-228
    • Kahl, R.1
  • 13
    • 0024445343 scopus 로고
    • Production of reactive oxygen species due to metabolic activation of butylated hydroxyanisole
    • Kahl R, Weinke S and Kappus H (1989) Production of reactive oxygen species due to metabolic activation of butylated hydroxyanisole. Toxicology 59:179-194.
    • (1989) Toxicology , vol.59 , pp. 179-194
    • Kahl, R.1    Weinke, S.2    Kappus, H.3
  • 14
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implication in tissue kinetics
    • Kerr JF, Wyllie AH and Currie AR (1972) Apoptosis: A basic biological phenomenon with wide-ranging implication in tissue kinetics. Br J Cancer 26:239-257.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 15
    • 0032882988 scopus 로고    scopus 로고
    • Dietary compounds that induce cancer preventive phase 2 enzymes activate apoptosis at comparable doses in HT29 colon carcinoma cells
    • Kirlin WG, Cai J, Delong MJ, Patten EJ and Jones DP (1999) Dietary compounds that induce cancer preventive phase 2 enzymes activate apoptosis at comparable doses in HT29 colon carcinoma cells. J Nutr 129:1827-1835.
    • (1999) J Nutr , vol.129 , pp. 1827-1835
    • Kirlin, W.G.1    Cai, J.2    Delong, M.J.3    Patten, E.J.4    Jones, D.P.5
  • 16
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • Luo X, Budihardjo I, Zou H, Slaughter C and Wang X (1998) Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94:481-490.
    • (1998) Cell , vol.94 , pp. 481-490
    • Luo, X.1    Budihardjo, I.2    Zou, H.3    Slaughter, C.4    Wang, X.5
  • 17
    • 0020053768 scopus 로고
    • Elevation of conjugation of capaity in isolated hepatocytes from BHA-treated mice
    • Moldéus P, Dock L, Cha Y-N, Berggren M and Jernstrom B (1982) Elevation of conjugation of capaity in isolated hepatocytes from BHA-treated mice. Biochem Pharmcol 31:1907-1910.
    • (1982) Biochem Pharmcol , vol.31 , pp. 1907-1910
    • Moldéus, P.1    Dock, L.2    Cha, Y.-N.3    Berggren, M.4    Jernstrom, B.5
  • 18
    • 0028170461 scopus 로고
    • On the mechanisms of 3-tert-butyl-4-hydroxyanisole- and its metabolites-induced cytotoxicities in isolated rat hepatocytes
    • Nakagawa Y, Nakajima K, Moore G and Moldéus P (1994) On the mechanisms of 3-tert-butyl-4-hydroxyanisole- and its metabolites-induced cytotoxicities in isolated rat hepatocytes. Eur J Pharmcolol 270:341-348.
    • (1994) Eur J Pharmcolol , vol.270 , pp. 341-348
    • Nakagawa, Y.1    Nakajima, K.2    Moore, G.3    Moldéus, P.4
  • 19
    • 0024214130 scopus 로고
    • A carcinogenesis reversibility study of the effects of butylated hydroxyanisole on the forestomach and urinary bladder in male fisher 344 rats
    • Nera EA, Iverson F, Lok E, Armstrong CL, Karpinski K and Clayson DB (1988) A carcinogenesis reversibility study of the effects of butylated hydroxyanisole on the forestomach and urinary bladder in male fisher 344 rats. Toxicology 53:251-268.
    • (1988) Toxicology , vol.53 , pp. 251-268
    • Nera, E.A.1    Iverson, F.2    Lok, E.3    Armstrong, C.L.4    Karpinski, K.5    Clayson, D.B.6
  • 20
    • 0033580926 scopus 로고    scopus 로고
    • Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation
    • Saleh A, Srinivasula SM, Acharya S, Fishel R and Alnemri ES (1999) cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation. J Biol Chem 274:17941-17945.
    • (1999) J Biol Chem , vol.274 , pp. 17941-17945
    • Saleh, A.1    Srinivasula, S.M.2    Acharya, S.3    Fishel, R.4    Alnemri, E.S.5
  • 21
    • 0027278951 scopus 로고
    • Oxygen radical formation during prostaglandin H synthase-mediated biotransformation of butylated hydroxyanisole
    • Schilderman PAEL, van Maanen JMS, Sweets EJ, ten Hoor F and Kleinjans JCS (1993) Oxygen radical formation during prostaglandin H synthase-mediated biotransformation of butylated hydroxyanisole. Carcinogenesis 14:347-353.
    • (1993) Carcinogenesis , vol.14 , pp. 347-353
    • Schilderman, P.A.E.L.1    Van Maanen, J.M.S.2    Sweets, E.J.3    Ten Hoor, F.4    Kleinjans, J.C.S.5
  • 24
    • 0001329989 scopus 로고    scopus 로고
    • Isolation of mitochondria from cells and tissues
    • (Spector DL, Goldman RD, and Leinwand LA, eds) Cold Spring Harbor Laboratory Press, New York
    • Spector DL (1998) Isolation of mitochondria from cells and tissues. in Cells: A Laboratory Manual (Spector DL, Goldman RD, and Leinwand LA, eds) pp 41.1-41.7, Cold Spring Harbor Laboratory Press, New York.
    • (1998) Cells: A Laboratory Manual , pp. 411-417
    • Spector, D.L.1
  • 25
    • 0029905073 scopus 로고    scopus 로고
    • Molecular ordering of the Fas-apoptotic pathway: The Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases
    • Srinivasula SM, Ahmad M, Fernandes Alnemri T, Litwack G and Alnemri ES (1996) Molecular ordering of the Fas-apoptotic pathway: The Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases. Proc Natl Acad Sci USA 93:14486-14491.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14486-14491
    • Srinivasula, S.M.1    Ahmad, M.2    Fernandes Alnemri, T.3    Litwack, G.4    Alnemri, E.S.5
  • 26
    • 0030785790 scopus 로고    scopus 로고
    • The central executioner of apoptosis: Multiple connections between protease activation and mitochondria in Fas/Apo-1/CD95- and ceramide-induced apoptosis
    • Susin SA, Zamzami N, Castedo M, Daugas E, Wang H-G, Geley S, Fassy F, Reed JC and Kroemer G (1997) The central executioner of apoptosis: Multiple connections between protease activation and mitochondria in Fas/Apo-1/CD95- and ceramide-induced apoptosis. J Exp Med 186:25-37.
    • (1997) J Exp Med , vol.186 , pp. 25-37
    • Susin, S.A.1    Zamzami, N.2    Castedo, M.3    Daugas, E.4    Wang, H.-G.5    Geley, S.6    Fassy, F.7    Reed, J.C.8    Kroemer, G.9
  • 27
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson C (1995) Apoptosis in the pathogenesis and treatment of disease. Science (Wash DC) 267:1456-1462.
    • (1995) Science (Wash DC) , vol.267 , pp. 1456-1462
    • Thompson, C.1
  • 28
    • 0023890168 scopus 로고
    • Cytotoxicity of butylated hydroxyanisole and butylated hydroxytoluene in isolated rat hepatocytes
    • Thompson D and Moldéus P (1988) Cytotoxicity of butylated hydroxyanisole and butylated hydroxytoluene in isolated rat hepatocytes. Biochem Pharmacol 37: 2201-2207.
    • (1988) Biochem Pharmacol , vol.37 , pp. 2201-2207
    • Thompson, D.1    Moldéus, P.2
  • 29
    • 0024598699 scopus 로고
    • The peroxidase-dependent activation of butylated hydroxyanisole and butylated hydroxytoluene (BHT) to reactive intermediates
    • Thompson DC, Cha Y-N and Trush MA (1989) The peroxidase-dependent activation of butylated hydroxyanisole and butylated hydroxytoluene (BHT) to reactive intermediates. J Biol Chem 264:3957-3965.
    • (1989) J Biol Chem , vol.264 , pp. 3957-3965
    • Thompson, D.C.1    Cha, Y.-N.2    Trush, M.A.3
  • 31
    • 0015826132 scopus 로고
    • Inhibition of chemical carcinogen-induced pulmonary neoplasia by butylated hydroxyanisole
    • Wattenberg LW (1973) Inhibition of chemical carcinogen-induced pulmonary neoplasia by butylated hydroxyanisole. J Natl Cancer Inst 50:1541-1544.
    • (1973) J Natl Cancer Inst , vol.50 , pp. 1541-1544
    • Wattenberg, L.W.1
  • 34
    • 0032007312 scopus 로고    scopus 로고
    • Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity
    • Yu R, Mandlekar S, Harvey KJ, Ucker DS and Kong A-NT (1998) Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res 58:402-408.
    • (1998) Cancer Res , vol.58 , pp. 402-408
    • Yu, R.1    Mandlekar, S.2    Harvey, K.J.3    Ucker, D.S.4    Kong, A.-N.T.5
  • 35
    • 0034723357 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase negatively regulates the induction of phase II drug-metabolizing enzymes that detoxify carcinogens
    • Yu R, Mandlekar S, Lei W, Fahl WE, Tan T-H and Kong A-NT (1999) p38 mitogen-activated protein kinase negatively regulates the induction of phase II drug-metabolizing enzymes that detoxify carcinogens. J Biol Chem 275:2322-2372.
    • (1999) J Biol Chem , vol.275 , pp. 2322-2372
    • Yu, R.1    Mandlekar, S.2    Lei, W.3    Fahl, W.E.4    Tan, T.-H.5    Kong, A.-N.T.6
  • 36
    • 0030663720 scopus 로고    scopus 로고
    • Butylated hydroxyanisole and its metabolite tert-butylhydroquinone differentially regulate mitogen-activated protein kinases. The role of oxidative stress in the activation of mitogen-activated protein kinases by phenolic antioxidants
    • Yu R, Tan T-H and Kong A-NT (1997) Butylated hydroxyanisole and its metabolite tert-butylhydroquinone differentially regulate mitogen-activated protein kinases. The role of oxidative stress in the activation of mitogen-activated protein kinases by phenolic antioxidants. J Biol Chem 272:28962-28970.
    • (1997) J Biol Chem , vol.272 , pp. 28962-28970
    • Yu, R.1    Tan, T.-H.2    Kong, A.-N.T.3
  • 37
    • 0030745646 scopus 로고    scopus 로고
    • Apaf-1, a human protein homologous to c. Elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
    • Zou H, Henzel WJ, Lui X, Lutschg A and Wang X (1997) Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90:405-413.
    • (1997) Cell , vol.90 , pp. 405-413
    • Zou, H.1    Henzel, W.J.2    Lui, X.3    Lutschg, A.4    Wang, X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.