Exploring the binding site structure of the PPARγ ligand-binding domain by computational solvent mapping

Biochemistry

Volumn 44, Issue 4, 2005, Pages 1193-1209

  Sheu, Shu Hsien ^a   Kaya, Taner ^b   Waxman, David J ^b   Vajda, Sandor ^a  

^a Boston University   (United States)

^b Boston University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTALLIZATION; DIMERIZATION; FREE ENERGY; MAPPING; ORGANIC COMPOUNDS; SOLVENTS;

APOSTRUCTURES; CO-ACTIVATOR BINDING SITES; LIGAND-BINDING DOMAIN (LBD); SOLVENT MAPPING;

PROTEINS;

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ARTICLE; BINDING SITE; COMPUTATIONAL SOLVENT MAPPING; CONFORMATIONAL TRANSITION; CORRELATION ANALYSIS; LIGAND BINDING; MATHEMATICAL COMPUTING; MOLECULAR PROBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; RELIABILITY; STRUCTURE ANALYSIS;

BINDING SITES; CINNAMATES; COMPUTATIONAL BIOLOGY; HUMANS; LIGANDS; OXAZINES; OXAZOLES; PHENYLPROPIONATES; PPAR GAMMA; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; SOLVENTS; THIAZOLES; THIAZOLIDINEDIONES; THIAZOLIDINES; TYROSINE;

EID: 13444265957     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048032c     Document Type: Article

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