Locating interaction sites on proteins: The crystal structure of thermolysin soaked in 2% to 100% isopropanol

Proteins: Structure, Function and Genetics

Volumn 37, Issue 4, 1999, Pages 628-640

  English, Andrew C ^a   Done, Sarah H ^a,b   Caves, Leo S D ^a   Groom, Colin R ^b   Hubbard, Roderick E ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

Binding sites; Drug design; Inhibitors; Organic solvent; X ray crystallography

Indexed keywords

2 PROPANOL; ORGANIC SOLVENT; PROTEIN; THERMOLYSIN;

ARTICLE; BINDING SITE; CHEMICAL INTERACTION; CRYSTAL STRUCTURE; DRUG DESIGN; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY;

2-PROPANOL; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DIMETHYL SULFOXIDE; ELECTROSTATICS; FOURIER ANALYSIS; MODELS, MOLECULAR; PROTEASE INHIBITORS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SOLVENTS; THERMODYNAMICS; THERMOLYSIN;

EID: 0032705748     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0134(19991201)37:4<628::AID-PROT13>3.0.CO;2-G     Document Type: Article

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