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Volumn 31, Issue SUPPL. 17, 2004, Pages 3-9

Angiogenesis and its role in colorectal tumor and metastasis formation

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOGENIC FACTOR; ANGIOGENIN; ANGIOPOIETIN; ANGIOPOIETIN RECEPTOR; ANTINEOPLASTIC AGENT; BEVACIZUMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR; INTEGRIN; MONOCLONAL ANTIBODY; PLATELET DERIVED ENDOTHELIAL CELL GROWTH FACTOR; THROMBOSPONDIN; THROMBOSPONDIN 1; THROMBOSPONDIN 2; THYMIDINE PHOSPHORYLASE; TRANSFORMING GROWTH FACTOR ALPHA; VASCULOTROPIN; VASCULOTROPIN ANTIBODY; VASCULOTROPIN INHIBITOR;

EID: 13244291423     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.seminoncol.2004.11.028     Document Type: Article
Times cited : (48)

References (82)
  • 1
    • 0026525407 scopus 로고
    • Interferon alfa-2a therapy for life-threatening hemangiomas of infancy
    • R.A. Ezekowitz, J.B. Mulliken, J. Folkman Interferon alfa-2a therapy for life-threatening hemangiomas of infancy N Engl J Med 326 1992 1456 1463
    • (1992) N Engl J Med , vol.326 , pp. 1456-1463
    • Ezekowitz, R.A.1    Mulliken, J.B.2    Folkman, J.3
  • 2
    • 0034499732 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and the regulation of angiogenesis
    • N. Ferrara Vascular endothelial growth factor and the regulation of angiogenesis Recent Prog Horm Res 55 2000 15 35 discussion 35-36
    • (2000) Recent Prog Horm Res , vol.55 , pp. 15-35
    • Ferrara, N.1
  • 3
    • 0030512608 scopus 로고    scopus 로고
    • Transgenic mouse models of tumour angiogenesis: The angiogenic switch, its molecular controls, and prospects for preclinical therapeutic models
    • D. Hanahan, G. Christofori, P. Naik Transgenic mouse models of tumour angiogenesis The angiogenic switch, its molecular controls, and prospects for preclinical therapeutic models Eur J Cancer 32A 1996 2386 2393
    • (1996) Eur J Cancer , vol.32 , pp. 2386-2393
    • Hanahan, D.1    Christofori, G.2    Naik, P.3
  • 4
    • 0032544686 scopus 로고    scopus 로고
    • Tumor induction of VEGF promoter activity in stromal cells
    • D. Fukumura, R. Xavier, T. Sugiura Tumor induction of VEGF promoter activity in stromal cells Cell 94 1998 715 725
    • (1998) Cell , vol.94 , pp. 715-725
    • Fukumura, D.1    Xavier, R.2    Sugiura, T.3
  • 5
    • 0001845719 scopus 로고    scopus 로고
    • Biology of cancer: Angiogenesis
    • V.T. DeVita S. Hellman S.A. Rosenberg Lippincott Williams & Wilkins Philadelphia, PA
    • I. Fidler, R. Kerbel, L. Ellis Biology of cancer Angiogenesis V.T. DeVita S. Hellman S.A. Rosenberg Cancer Principles and Practice of Oncology 2001 Lippincott Williams & Wilkins Philadelphia, PA 137 147
    • (2001) Cancer: Principles and Practice of Oncology , pp. 137-147
    • Fidler, I.1    Kerbel, R.2    Ellis, L.3
  • 6
    • 0028114985 scopus 로고
    • The implications of angiogenesis for the biology and therapy of cancer metastasis
    • I.J. Fidler, L.M. Ellis The implications of angiogenesis for the biology and therapy of cancer metastasis Cell 79 1994 185 188
    • (1994) Cell , vol.79 , pp. 185-188
    • Fidler, I.J.1    Ellis, L.M.2
  • 7
    • 0031866049 scopus 로고    scopus 로고
    • Molecular determinants of angiogenesis in cancer metastasis
    • I.J. Fidler, R. Kumar, D.R. Bielenberg Molecular determinants of angiogenesis in cancer metastasis Cancer J Sci Am 4 suppl 1 1998 S58 S66
    • (1998) Cancer J Sci Am , vol.4 , Issue.1 SUPPL.
    • Fidler, I.J.1    Kumar, R.2    Bielenberg, D.R.3
  • 8
    • 0030498734 scopus 로고    scopus 로고
    • Angiogenesis and metastasis
    • L.M. Ellis, I.J. Fidler Angiogenesis and metastasis Eur J Cancer 32A 1996 2451 2460
    • (1996) Eur J Cancer , vol.32 , pp. 2451-2460
    • Ellis, L.M.1    Fidler, I.J.2
  • 9
    • 0032007140 scopus 로고    scopus 로고
    • Vessel counts and vascular endothelial growth factor expression in pancreatic adenocarcinoma
    • L.M. Ellis, Y. Takahashi, C.J. Fenoglio Vessel counts and vascular endothelial growth factor expression in pancreatic adenocarcinoma Eur J Cancer 34 1998 337 340
    • (1998) Eur J Cancer , vol.34 , pp. 337-340
    • Ellis, L.M.1    Takahashi, Y.2    Fenoglio, C.J.3
  • 10
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent?
    • J. Folkman What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 82 1990 4 6
    • (1990) J Natl Cancer Inst , vol.82 , pp. 4-6
    • Folkman, J.1
  • 11
    • 18844473781 scopus 로고    scopus 로고
    • Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms
    • C.J. Bruns, M.T. Harbison, D.W. Davis Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms Clin Cancer Res 6 2000 1936 1948
    • (2000) Clin Cancer Res , vol.6 , pp. 1936-1948
    • Bruns, C.J.1    Harbison, M.T.2    Davis, D.W.3
  • 12
    • 84970070220 scopus 로고
    • Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer
    • Y. Takahashi, Y. Kitadai, C.D. Bucana Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer Cancer Res 55 1995 3964 3968
    • (1995) Cancer Res , vol.55 , pp. 3964-3968
    • Takahashi, Y.1    Kitadai, Y.2    Bucana, C.D.3
  • 13
    • 1842415455 scopus 로고    scopus 로고
    • Vessel counts and expression of vascular endothelial growth factor as prognostic factors in node-negative colon cancer
    • Y. Takahashi, S.L. Tucker, Y. Kitadai Vessel counts and expression of vascular endothelial growth factor as prognostic factors in node-negative colon cancer Arch Surg 132 1997 541 546
    • (1997) Arch Surg , vol.132 , pp. 541-546
    • Takahashi, Y.1    Tucker, S.L.2    Kitadai, Y.3
  • 14
    • 0030037264 scopus 로고    scopus 로고
    • Angiogenesis as an unfavorable prognostic factor in human colorectal carcinoma
    • Y. Takebayashi, S. Aklyama, K. Yamada Angiogenesis as an unfavorable prognostic factor in human colorectal carcinoma Cancer 78 1996 226 231
    • (1996) Cancer , vol.78 , pp. 226-231
    • Takebayashi, Y.1    Aklyama, S.2    Yamada, K.3
  • 15
    • 0032919961 scopus 로고    scopus 로고
    • Prospective study of intratumoral microvessel density, p53 expression and survival in colorectal cancer
    • P.B. Vermeulen, G.G. Van den Eynden, P. Huget Prospective study of intratumoral microvessel density, p53 expression and survival in colorectal cancer Br J Cancer 79 1999 316 322
    • (1999) Br J Cancer , vol.79 , pp. 316-322
    • Vermeulen, P.B.1    Van Den Eynden, G.G.2    Huget, P.3
  • 16
    • 0034255151 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is an in vivo survival factor for tumor endothelium in a murine model of colorectal carcinoma liver metastases
    • C.J. Bruns, W. Liu, D.W. Davis Vascular endothelial growth factor is an in vivo survival factor for tumor endothelium in a murine model of colorectal carcinoma liver metastases Cancer 89 2000 488 499
    • (2000) Cancer , vol.89 , pp. 488-499
    • Bruns, C.J.1    Liu, W.2    Davis, D.W.3
  • 17
    • 0033963827 scopus 로고    scopus 로고
    • Enhancement of angiogenesis, tumor growth, and metastasis by transfection of vascular endothelial growth factor into LoVo human colon cancer cell line
    • Y. Kondo, S. Arii, A. Mori Enhancement of angiogenesis, tumor growth, and metastasis by transfection of vascular endothelial growth factor into LoVo human colon cancer cell line Clin Cancer Res 6 2000 622 630
    • (2000) Clin Cancer Res , vol.6 , pp. 622-630
    • Kondo, Y.1    Arii, S.2    Mori, A.3
  • 18
    • 0034028399 scopus 로고    scopus 로고
    • Vegf, Vegf-B, Vegf-C and their receptors KDR, FLT-1 and FLT-4 during the neoplastic progression of human colonic mucosa
    • T. Andre, L. Kotelevets, J.C. Vaillant Vegf, Vegf-B, Vegf-C and their receptors KDR, FLT-1 and FLT-4 during the neoplastic progression of human colonic mucosa Int J Cancer 86 2000 174 181
    • (2000) Int J Cancer , vol.86 , pp. 174-181
    • Andre, T.1    Kotelevets, L.2    Vaillant, J.C.3
  • 19
    • 0033231069 scopus 로고    scopus 로고
    • Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis
    • R.M. Shaheen, D.W. Davis, W. Liu Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis Cancer Res 59 1999 5412 5416
    • (1999) Cancer Res , vol.59 , pp. 5412-5416
    • Shaheen, R.M.1    Davis, D.W.2    Liu, W.3
  • 20
    • 0035866334 scopus 로고    scopus 로고
    • Tyrosine kinase inhibition of multiple angiogenic growth factor receptors improves survival in mice bearing colon cancer liver metastases by inhibition of endothelial cell survival mechanisms
    • R.M. Shaheen, W.W. Tseng, D.W. Davis Tyrosine kinase inhibition of multiple angiogenic growth factor receptors improves survival in mice bearing colon cancer liver metastases by inhibition of endothelial cell survival mechanisms Cancer Res 61 2001 1464 1468
    • (2001) Cancer Res , vol.61 , pp. 1464-1468
    • Shaheen, R.M.1    Tseng, W.W.2    Davis, D.W.3
  • 21
    • 17944370631 scopus 로고    scopus 로고
    • Inhibited growth of colon cancer carcinomatosis by antibodies to vascular endothelial and epidermal growth factor receptors
    • R.M. Shaheen, S.A. Ahmad, W. Liu Inhibited growth of colon cancer carcinomatosis by antibodies to vascular endothelial and epidermal growth factor receptors Br J Cancer 85 2001 584 589
    • (2001) Br J Cancer , vol.85 , pp. 584-589
    • Shaheen, R.M.1    Ahmad, S.A.2    Liu, W.3
  • 22
    • 0035261289 scopus 로고    scopus 로고
    • Effects of an antibody to vascular endothelial growth factor receptor-2 on survival, tumor vascularity, and apoptosis in a murine model of colon carcinomatosis
    • R.M. Shaheen, W.W. Tseng, R. Vellagas Effects of an antibody to vascular endothelial growth factor receptor-2 on survival, tumor vascularity, and apoptosis in a murine model of colon carcinomatosis Int J Oncol 18 2001 221 226
    • (2001) Int J Oncol , vol.18 , pp. 221-226
    • Shaheen, R.M.1    Tseng, W.W.2    Vellagas, R.3
  • 23
    • 0029004025 scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
    • H.F. Dvorak, L.F. Brown, M. Detmar Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis Am J Pathol 146 1995 1029 1039
    • (1995) Am J Pathol , vol.146 , pp. 1029-1039
    • Dvorak, H.F.1    Brown, L.F.2    Detmar, M.3
  • 24
    • 4244078727 scopus 로고    scopus 로고
    • VEGF receptor signal transduction
    • T. Matsumoto, L. Claesson-Welsh VEGF receptor signal transduction Sci STKE 2001 2001 RE21
    • (2001) Sci STKE , vol.2001 , pp. 21
    • Matsumoto, T.1    Claesson-Welsh, L.2
  • 25
    • 0034646262 scopus 로고    scopus 로고
    • Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: In vivo expression and antitumor activity
    • M.L. Gagnon, D.R. Bielenberg, Z. Gechtman Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor In vivo expression and antitumor activity Proc Natl Acad Sci U S A 97 2000 2573 2578
    • (2000) Proc Natl Acad Sci U S a , vol.97 , pp. 2573-2578
    • Gagnon, M.L.1    Bielenberg, D.R.2    Gechtman, Z.3
  • 26
    • 0642372571 scopus 로고    scopus 로고
    • Angiogenesis and antiangiogenic therapy of colon cancer liver metastasis
    • O. Stoeltzing, W. Liu, N. Reinmuth Angiogenesis and antiangiogenic therapy of colon cancer liver metastasis Ann Surg Oncol 10 2003 722 733
    • (2003) Ann Surg Oncol , vol.10 , pp. 722-733
    • Stoeltzing, O.1    Liu, W.2    Reinmuth, N.3
  • 27
    • 0035992377 scopus 로고    scopus 로고
    • Vascular endothelial growth factor splice variants and their prognostic value in breast and ovarian cancer
    • M. Stimpfl, D. Tong, B. Fasching Vascular endothelial growth factor splice variants and their prognostic value in breast and ovarian cancer Clin Cancer Res 8 2002 2253 2259
    • (2002) Clin Cancer Res , vol.8 , pp. 2253-2259
    • Stimpfl, M.1    Tong, D.2    Fasching, B.3
  • 28
    • 0032713925 scopus 로고    scopus 로고
    • Vascular endothelial growth factor levels and induction of permeability in malignant pleural effusions
    • B.K. Zebrowski, S. Yano, W. Liu Vascular endothelial growth factor levels and induction of permeability in malignant pleural effusions Clin Cancer Res 5 1999 3364 3368
    • (1999) Clin Cancer Res , vol.5 , pp. 3364-3368
    • Zebrowski, B.K.1    Yano, S.2    Liu, W.3
  • 29
    • 0033050656 scopus 로고    scopus 로고
    • Markedly elevated levels of vascular endothelial growth factor in malignant ascites
    • B.K. Zebrowski, W. Liu, K. Ramirez Markedly elevated levels of vascular endothelial growth factor in malignant ascites Ann Surg Oncol 6 1999 373 378
    • (1999) Ann Surg Oncol , vol.6 , pp. 373-378
    • Zebrowski, B.K.1    Liu, W.2    Ramirez, K.3
  • 30
    • 0036240885 scopus 로고    scopus 로고
    • Clinical experience with angiogenesis signaling inhibitors: Focus on vascular endothelial growth factor (VEGF) blockers
    • L.S. Rosen Clinical experience with angiogenesis signaling inhibitors Focus on vascular endothelial growth factor (VEGF) blockers Cancer Control 9 2002 36 44
    • (2002) Cancer Control , vol.9 , pp. 36-44
    • Rosen, L.S.1
  • 31
    • 0036344495 scopus 로고    scopus 로고
    • Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1
    • A. Luttun, M. Tjwa, L. Moons Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1 Nat Med 8 2002 831 840
    • (2002) Nat Med , vol.8 , pp. 831-840
    • Luttun, A.1    Tjwa, M.2    Moons, L.3
  • 32
    • 13244274047 scopus 로고    scopus 로고
    • Monoclonal antibody against VEGFR1 inhibits flt-1 positive breast tumor growth by a dual mechanism involving anti-endothelial and anti-tumor cell growth activities
    • Y. Wu, C. Costa, S. Dias Monoclonal antibody against VEGFR1 inhibits flt-1 positive breast tumor growth by a dual mechanism involving anti-endothelial and anti-tumor cell growth activities Proc Am Assoc Cancer Res 43 2002 527 (abstr 2613)
    • (2002) Proc Am Assoc Cancer Res , vol.43 , pp. 527
    • Wu, Y.1    Costa, C.2    Dias, S.3
  • 33
    • 0037024472 scopus 로고    scopus 로고
    • Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling
    • Y. He, K. Kozaki, T. Karpanen Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling J Natl Cancer Inst 94 2002 819 825
    • (2002) J Natl Cancer Inst , vol.94 , pp. 819-825
    • He, Y.1    Kozaki, K.2    Karpanen, T.3
  • 34
    • 0032549799 scopus 로고    scopus 로고
    • Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
    • S. Soker, S. Takashima, H.Q. Miao Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor Cell 92 1998 735 745
    • (1998) Cell , vol.92 , pp. 735-745
    • Soker, S.1    Takashima, S.2    Miao, H.Q.3
  • 35
    • 2442639176 scopus 로고    scopus 로고
    • Neuropilin-1 in human colon cancer: Expression, regulation, and role in induction of angiogenesis
    • A.A. Parikh, F. Fan, W.B. Liu Neuropilin-1 in human colon cancer Expression, regulation, and role in induction of angiogenesis Am J Pathol 164 2004 2139 2151
    • (2004) Am J Pathol , vol.164 , pp. 2139-2151
    • Parikh, A.A.1    Fan, F.2    Liu, W.B.3
  • 36
    • 0024563134 scopus 로고
    • Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor
    • F. Ishikawa, K. Miyazono, U. Hellman Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor Nature 338 1989 557 562
    • (1989) Nature , vol.338 , pp. 557-562
    • Ishikawa, F.1    Miyazono, K.2    Hellman, U.3
  • 37
    • 0029905939 scopus 로고    scopus 로고
    • Multiparametric in situ mRNA hybridization analysis to predict disease recurrence in patients with colon carcinoma
    • Y. Kitadai, L.M. Ellis, S.L. Tucker Multiparametric in situ mRNA hybridization analysis to predict disease recurrence in patients with colon carcinoma Am J Pathol 149 1996 1541 1551
    • (1996) Am J Pathol , vol.149 , pp. 1541-1551
    • Kitadai, Y.1    Ellis, L.M.2    Tucker, S.L.3
  • 38
    • 0030700901 scopus 로고    scopus 로고
    • Association of vascular endothelial growth factor expression with tumor angiogenesis, survival and thymidine phosphorylase/platelet-derived endothelial cell growth factor expression in human colorectal cancer
    • H. Amaya, N. Tanigawa, C. Lu Association of vascular endothelial growth factor expression with tumor angiogenesis, survival and thymidine phosphorylase/platelet-derived endothelial cell growth factor expression in human colorectal cancer Cancer Lett 119 1997 227 235
    • (1997) Cancer Lett , vol.119 , pp. 227-235
    • Amaya, H.1    Tanigawa, N.2    Lu, C.3
  • 39
    • 0031203910 scopus 로고    scopus 로고
    • Correlation between expression of platelet-derived endothelial cell growth factor (thymidine phosphorylase) and microvessel density in early-stage human colon carcinomas
    • T. Saeki, M. Tanada, S. Takashima Correlation between expression of platelet-derived endothelial cell growth factor (thymidine phosphorylase) and microvessel density in early-stage human colon carcinomas Jpn J Clin Oncol 27 1997 227 230
    • (1997) Jpn J Clin Oncol , vol.27 , pp. 227-230
    • Saeki, T.1    Tanada, M.2    Takashima, S.3
  • 40
    • 0034989658 scopus 로고    scopus 로고
    • Developmental roles of platelet-derived growth factors
    • C. Betsholtz, L. Karlsson, P. Lindahl Developmental roles of platelet-derived growth factors Bioessays 23 2001 494 507
    • (2001) Bioessays , vol.23 , pp. 494-507
    • Betsholtz, C.1    Karlsson, L.2    Lindahl, P.3
  • 41
    • 0032768156 scopus 로고    scopus 로고
    • Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse
    • M. Hellstrom, M. Kalen, P. Lindahl Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse Development 126 1999 3047 3055
    • (1999) Development , vol.126 , pp. 3047-3055
    • Hellstrom, M.1    Kalen, M.2    Lindahl, P.3
  • 42
    • 0028808015 scopus 로고
    • Platelet-derived growth factor-B increases colon cancer cell growth in vivo by a paracrine effect
    • S. Hsu, F. Huang, E. Friedman Platelet-derived growth factor-B increases colon cancer cell growth in vivo by a paracrine effect J Cell Physiol 165 1995 239 245
    • (1995) J Cell Physiol , vol.165 , pp. 239-245
    • Hsu, S.1    Huang, F.2    Friedman, E.3
  • 43
    • 0035347301 scopus 로고    scopus 로고
    • Induction of VEGF in perivascular cells defines a potential paracrine mechanism for endothelial cell survival
    • N. Reinmuth, W. Liu, Y.D. Jung Induction of VEGF in perivascular cells defines a potential paracrine mechanism for endothelial cell survival FASEB J 15 2001 1239 1241
    • (2001) FASEB J , vol.15 , pp. 1239-1241
    • Reinmuth, N.1    Liu, W.2    Jung, Y.D.3
  • 44
    • 0032747902 scopus 로고    scopus 로고
    • Factors promoting tumor angiogenesis
    • M.E. Beckner Factors promoting tumor angiogenesis Cancer Invest 17 1999 594 623
    • (1999) Cancer Invest , vol.17 , pp. 594-623
    • Beckner, M.E.1
  • 45
    • 0032925623 scopus 로고    scopus 로고
    • Increased serum angiogenin concentration in colorectal cancer is correlated with cancer progression
    • S. Shimoyama, K. Yamasaki, M. Kawahara Increased serum angiogenin concentration in colorectal cancer is correlated with cancer progression Clin Cancer Res 5 1999 1125 1130
    • (1999) Clin Cancer Res , vol.5 , pp. 1125-1130
    • Shimoyama, S.1    Yamasaki, K.2    Kawahara, M.3
  • 46
    • 0033822949 scopus 로고    scopus 로고
    • Angiogenin expression in human colorectal cancer: The role of focal macrophage infiltration
    • T. Etoh, K. Shibuta, G.F. Barnard Angiogenin expression in human colorectal cancer The role of focal macrophage infiltration Clin Cancer Res 6 2000 3545 3551
    • (2000) Clin Cancer Res , vol.6 , pp. 3545-3551
    • Etoh, T.1    Shibuta, K.2    Barnard, G.F.3
  • 47
    • 0344450778 scopus 로고    scopus 로고
    • Direct actions of angiopoietin-1 on human endothelium: Evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors
    • A. Papapetropoulos, G. Garcia-Cardena, T.J. Dengler Direct actions of angiopoietin-1 on human endothelium Evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors Lab Invest 79 1999 213 223
    • (1999) Lab Invest , vol.79 , pp. 213-223
    • Papapetropoulos, A.1    Garcia-Cardena, G.2    Dengler, T.J.3
  • 48
    • 0031738823 scopus 로고    scopus 로고
    • Is angiopoietin-2 necessary for the initiation of tumor angiogenesis?
    • J. Lauren, Y. Gunji, K. Alitalo Is angiopoietin-2 necessary for the initiation of tumor angiogenesis? Am J Pathol 153 1998 1333 1339
    • (1998) Am J Pathol , vol.153 , pp. 1333-1339
    • Lauren, J.1    Gunji, Y.2    Alitalo, K.3
  • 49
  • 50
    • 0242405592 scopus 로고    scopus 로고
    • Role of angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis
    • G. Thurston Role of angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis Cell Tissue Res 314 2003 61 68
    • (2003) Cell Tissue Res , vol.314 , pp. 61-68
    • Thurston, G.1
  • 51
    • 0035447959 scopus 로고    scopus 로고
    • Differential expression of angiopoietin-1 and angiopoietin-2 in colon carcinoma: Possible mechanism for initiation of angiogenesis
    • S. Ahmad, W. Liu, Y. Jung Differential expression of angiopoietin-1 and angiopoietin-2 in colon carcinoma Possible mechanism for initiation of angiogenesis Cancer 92 2001 1138 1143
    • (2001) Cancer , vol.92 , pp. 1138-1143
    • Ahmad, S.1    Liu, W.2    Jung, Y.3
  • 52
    • 0038407310 scopus 로고    scopus 로고
    • Angiopoietin-1 inhibits vascular permeability, angiogenesis, and growth of hepatic colon cancer tumors
    • O. Stoeltzing, S.A. Ahmad, W. Liu Angiopoietin-1 inhibits vascular permeability, angiogenesis, and growth of hepatic colon cancer tumors Cancer Res 63 2003 3370 3377
    • (2003) Cancer Res , vol.63 , pp. 3370-3377
    • Stoeltzing, O.1    Ahmad, S.A.2    Liu, W.3
  • 53
    • 0035866389 scopus 로고    scopus 로고
    • The effects of angiopoietin-1 and -2 on tumor growth and angiogenesis in human colon cancer
    • S.A. Ahmad, W. Liu, Y.D. Jung The effects of angiopoietin-1 and -2 on tumor growth and angiogenesis in human colon cancer Cancer Res 61 2001 1255 1259
    • (2001) Cancer Res , vol.61 , pp. 1255-1259
    • Ahmad, S.A.1    Liu, W.2    Jung, Y.D.3
  • 54
    • 0034036689 scopus 로고    scopus 로고
    • Angiopoietin-1 protects the adult vasculature against plasma leakage
    • G. Thurston, J.S. Rudge, E. Ioffe Angiopoietin-1 protects the adult vasculature against plasma leakage Nat Med 6 2000 460 463
    • (2000) Nat Med , vol.6 , pp. 460-463
    • Thurston, G.1    Rudge, J.S.2    Ioffe, E.3
  • 55
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • R.O. Hynes Integrins Versatility, modulation, and signaling in cell adhesion Cell 69 1992 11 25
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 56
    • 0028362876 scopus 로고
    • Requirement of vascular integrin alpha v beta 3 for angiogenesis
    • P.C. Brooks, R.A. Clark, D.A. Cheresh Requirement of vascular integrin alpha v beta 3 for angiogenesis Science 264 1994 569 571
    • (1994) Science , vol.264 , pp. 569-571
    • Brooks, P.C.1    Clark, R.A.2    Cheresh, D.A.3
  • 57
    • 0028670833 scopus 로고
    • Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
    • P.C. Brooks, A.M. Montgomery, M. Rosenfeld Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels Cell 79 1994 1157 1164
    • (1994) Cell , vol.79 , pp. 1157-1164
    • Brooks, P.C.1    Montgomery, A.M.2    Rosenfeld, M.3
  • 58
    • 0028972105 scopus 로고
    • Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin
    • P.C. Brooks, S. Stromblad, R. Klemke Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin J Clin Invest 96 1995 1815 1822
    • (1995) J Clin Invest , vol.96 , pp. 1815-1822
    • Brooks, P.C.1    Stromblad, S.2    Klemke, R.3
  • 59
    • 0028057613 scopus 로고
    • Disruption of epithelial cell-matrix interactions induces apoptosis
    • S.M. Frisch, H. Francis Disruption of epithelial cell-matrix interactions induces apoptosis J Cell Biol 124 1994 619 626
    • (1994) J Cell Biol , vol.124 , pp. 619-626
    • Frisch, S.M.1    Francis, H.2
  • 60
    • 0030038229 scopus 로고    scopus 로고
    • Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis
    • S. Stromblad, J.C. Becker, M. Yebra Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis J Clin Invest 98 1996 426 433
    • (1996) J Clin Invest , vol.98 , pp. 426-433
    • Stromblad, S.1    Becker, J.C.2    Yebra, M.3
  • 61
    • 0033121275 scopus 로고    scopus 로고
    • The role of alphav integrins during angiogenesis: Insights into potential mechanisms of action and clinical development
    • B.P. Eliceiri, D.A. Cheresh The role of alphav integrins during angiogenesis Insights into potential mechanisms of action and clinical development J Clin Invest 103 1999 1227 1230
    • (1999) J Clin Invest , vol.103 , pp. 1227-1230
    • Eliceiri, B.P.1    Cheresh, D.A.2
  • 62
    • 0037457423 scopus 로고    scopus 로고
    • Inhibition of integrin alpha5beta1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice
    • O. Stoeltzing, W. Liu, N. Reinmuth Inhibition of integrin alpha5beta1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice Int J Cancer 104 2003 496 503
    • (2003) Int J Cancer , vol.104 , pp. 496-503
    • Stoeltzing, O.1    Liu, W.2    Reinmuth, N.3
  • 63
    • 0037728975 scopus 로고    scopus 로고
    • Alphavbeta3 integrin antagonist S247 decreases colon cancer metastasis and angiogenesis and improves survival in mice
    • N. Reinmuth, W. Liu, S.A. Ahmad Alphavbeta3 integrin antagonist S247 decreases colon cancer metastasis and angiogenesis and improves survival in mice Cancer Res 63 2003 2079 2087
    • (2003) Cancer Res , vol.63 , pp. 2079-2087
    • Reinmuth, N.1    Liu, W.2    Ahmad, S.A.3
  • 64
    • 0032170035 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I
    • Y. Akagi, W. Liu, B. Zebrowski Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I Cancer Res 58 1998 4008 4014
    • (1998) Cancer Res , vol.58 , pp. 4008-4014
    • Akagi, Y.1    Liu, W.2    Zebrowski, B.3
  • 65
    • 0031800885 scopus 로고    scopus 로고
    • EGF, TGF-alpha, and EGF-R in human colorectal adenocarcinoma
    • C. Messa, F. Russo, M.G. Caruso EGF, TGF-alpha, and EGF-R in human colorectal adenocarcinoma Acta Oncol 37 1998 285 289
    • (1998) Acta Oncol , vol.37 , pp. 285-289
    • Messa, C.1    Russo, F.2    Caruso, M.G.3
  • 66
    • 0033105773 scopus 로고    scopus 로고
    • Thrombospondin-2 (TSP2) expression is inversely correlated with vascularity in glioma
    • M. Kazuno, T. Tokunaga, Y. Oshika Thrombospondin-2 (TSP2) expression is inversely correlated with vascularity in glioma Eur J Cancer 35 1999 502 506
    • (1999) Eur J Cancer , vol.35 , pp. 502-506
    • Kazuno, M.1    Tokunaga, T.2    Oshika, Y.3
  • 67
    • 0035403794 scopus 로고    scopus 로고
    • Expression of thrombospondin-1 inversely correlated with tumor vascularity and hematogenous metastasis in colon cancer
    • K. Maeda, Y. Nishiguchi, S.M. Kang Expression of thrombospondin-1 inversely correlated with tumor vascularity and hematogenous metastasis in colon cancer Oncol Rep 8 2001 763 766
    • (2001) Oncol Rep , vol.8 , pp. 763-766
    • Maeda, K.1    Nishiguchi, Y.2    Kang, S.M.3
  • 68
    • 1442359994 scopus 로고    scopus 로고
    • Thrombospondin-1 plus irinotecan: A novel antiangiogenic-chemotherapeutic combination that inhibits the growth of advanced human colon tumor xenografts in mice
    • G. Allegrini, F.A. Goulette, J.W. Darnowski Thrombospondin-1 plus irinotecan A novel antiangiogenic-chemotherapeutic combination that inhibits the growth of advanced human colon tumor xenografts in mice Cancer Chemother Pharmacol 53 2004 261 266
    • (2004) Cancer Chemother Pharmacol , vol.53 , pp. 261-266
    • Allegrini, G.1    Goulette, F.A.2    Darnowski, J.W.3
  • 69
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • H. Hurwitz, L. Fehrenbacher, W. Novotny Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer N Engl J Med 350 2004 2335 2342
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 70
    • 1642393197 scopus 로고    scopus 로고
    • Bevacizumab (B) plus gemcitabine (G) in patients (pts) with advanced pancreatic cancer (PC)
    • H. Kindler, R. Ansari, E. Lester Bevacizumab (B) plus gemcitabine (G) in patients (pts) with advanced pancreatic cancer (PC) Proc Am Soc Clin Oncol 22 2003 259 (abstr 1037)
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 259
    • Kindler, H.1    Ansari, R.2    Lester, E.3
  • 71
    • 0002235290 scopus 로고    scopus 로고
    • Phase III trial of capecitabine (Xeloda) plus bevacizumab (Avastin) versus capecitabine alone in women with metastatic breast cancer previously treated with an anthracycline and a taxane
    • K. Miller, H. Rugo, M. Cobleigh Phase III trial of capecitabine (Xeloda) plus bevacizumab (Avastin) versus capecitabine alone in women with metastatic breast cancer previously treated with an anthracycline and a taxane Breast Cancer Res Treat 76 2002 S37 (abstr)
    • (2002) Breast Cancer Res Treat , vol.76 , pp. 37
    • Miller, K.1    Rugo, H.2    Cobleigh, M.3
  • 72
    • 0000482702 scopus 로고    scopus 로고
    • Efficacy results of a phase I/II study of SU5416 (S)/5-fluorouracil (F)/leucovorin (L) relative to results in random subsets of similar patients (pts) from a phase III study of irinotecan (C)/F/L or F/L alone in the therapy of previously untreated metastatic colorectal cancer
    • L. Miller, G. Elfring, A. Hannah Efficacy results of a phase I/II study of SU5416 (S)/5-fluorouracil (F)/leucovorin (L) relative to results in random subsets of similar patients (pts) from a phase III study of irinotecan (C)/F/L or F/L alone in the therapy of previously untreated metastatic colorectal cancer Proc Am Soc Clin Oncol 20 2001 144a (abstr 571)
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • Miller, L.1    Elfring, G.2    Hannah, A.3
  • 73
    • 0034796595 scopus 로고    scopus 로고
    • Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy
    • R.K. Jain Normalizing tumor vasculature with anti-angiogenic therapy A new paradigm for combination therapy Nat Med 7 2001 987 989
    • (2001) Nat Med , vol.7 , pp. 987-989
    • Jain, R.K.1
  • 74
    • 2542628099 scopus 로고    scopus 로고
    • Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors
    • R.T. Tong, Y. Boucher, S.V. Kozin Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors Cancer Res 64 2004 3731 3736
    • (2004) Cancer Res , vol.64 , pp. 3731-3736
    • Tong, R.T.1    Boucher, Y.2    Kozin, S.V.3
  • 75
    • 0026786660 scopus 로고
    • Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: Implications for vascular collapse
    • Y. Boucher, R.K. Jain Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors Implications for vascular collapse Cancer Res 52 1992 5110 5114
    • (1992) Cancer Res , vol.52 , pp. 5110-5114
    • Boucher, Y.1    Jain, R.K.2
  • 76
    • 0029787909 scopus 로고    scopus 로고
    • Tumor angiogenesis and interstitial hypertension
    • Y. Boucher, M. Leunig, R.K. Jain Tumor angiogenesis and interstitial hypertension Cancer Res 56 1996 4264 4266
    • (1996) Cancer Res , vol.56 , pp. 4264-4266
    • Boucher, Y.1    Leunig, M.2    Jain, R.K.3
  • 77
    • 0034306974 scopus 로고    scopus 로고
    • Anti-vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions
    • C.G. Lee, M. Heijn, E. di Tomaso Anti-vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions Cancer Res 60 2000 5565 5570
    • (2000) Cancer Res , vol.60 , pp. 5565-5570
    • Lee, C.G.1    Heijn, M.2    Di Tomaso, E.3
  • 78
    • 11144354392 scopus 로고    scopus 로고
    • Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
    • C.G. Willett, Y. Boucher, E. di Tomaso Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer Nat Med 10 2004 145 147
    • (2004) Nat Med , vol.10 , pp. 145-147
    • Willett, C.G.1    Boucher, Y.2    Di Tomaso, E.3
  • 79
    • 0038235987 scopus 로고    scopus 로고
    • Effect of antivascular endothelial growth factor treatment on the intratumoral uptake of CPT-11
    • H. Wildiers, G. Guetens, G. De Boeck Effect of antivascular endothelial growth factor treatment on the intratumoral uptake of CPT-11 Br J Cancer 88 2003 1979 1986
    • (2003) Br J Cancer , vol.88 , pp. 1979-1986
    • Wildiers, H.1    Guetens, G.2    De Boeck, G.3
  • 80
    • 0038476590 scopus 로고    scopus 로고
    • Pharmacodynamic-mediated effects of the angiogenesis inhibitor SU5416 on the tumor disposition of temozolomide in subcutaneous and intracerebral glioma xenograft models
    • J. Ma, S. Li, K. Reed Pharmacodynamic-mediated effects of the angiogenesis inhibitor SU5416 on the tumor disposition of temozolomide in subcutaneous and intracerebral glioma xenograft models J Pharmacol Exp Ther 305 2003 833 839
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 833-839
    • Ma, J.1    Li, S.2    Reed, K.3
  • 81
    • 0036831559 scopus 로고    scopus 로고
    • Vascular and haematopoietic stem cells: Novel targets for anti-angiogenesis therapy?
    • S. Rafii, D. Lyden, R. Benezra Vascular and haematopoietic stem cells Novel targets for anti-angiogenesis therapy? Nat Rev Cancer 2 2002 826 835
    • (2002) Nat Rev Cancer , vol.2 , pp. 826-835
    • Rafii, S.1    Lyden, D.2    Benezra, R.3
  • 82
    • 2342522112 scopus 로고    scopus 로고
    • Interleukin-1beta regulates angiopoietin-1 expression in human endothelial cells
    • F. Fan, O. Stoeltzing, W. Liu Interleukin-1beta regulates angiopoietin-1 expression in human endothelial cells Cancer Res 64 2004 3186 3190
    • (2004) Cancer Res , vol.64 , pp. 3186-3190
    • Fan, F.1    Stoeltzing, O.2    Liu, W.3


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