The effects of angiopoietin-1 and -2 on tumor growth and angiogenesis in human colon cancer

Cancer Research

Volumn 61, Issue 4, 2001, Pages 1255-1259

  Ahmad, Syed A ^a   Liu, Wenbiao ^a   Jung, Young D ^a   Fan, Fan ^a   Wilson, Michael ^a   Reinmuth, Niels ^a   Shaheen, Raymond M ^a   Bucana, Corazon D ^a   Ellis, Lee M ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; COMPLEMENTARY DNA; MESSENGER RNA;

ANGIOGENESIS; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CELL VIABILITY; COLORECTAL CANCER; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; TUMOR BLOOD FLOW; TUMOR CELL; TUMOR GROWTH;

ANGIOPOIETIN-1; ANGIOPOIETIN-2; ANIMALS; APOPTOSIS; BLOTTING, NORTHERN; CELL DIVISION; COLONIC NEOPLASMS; ENDOTHELIUM, VASCULAR; HT29 CELLS; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN BIOSYNTHESIS; PROTEINS; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 0035866389     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Vascular endothelial growth factor and the angiopoietins: Working together to build a better blood vessel
2. Angiopoietin-2, a natural antagonist for Tie 2 that disrupts in vivo angiogenesis
3. Angiopoietin-1 promotes increased vascularization in vivo
4. Direct actions of angiopoietin-I on human endothelium: Evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors
5. Requisite role of angiopoietin-1, a ligand for the tie2 receptor, during embryonic angiogenesis
6. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
7. Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo
8. Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2 modulate VEGF-induced postnatal neovascularization
9. Chemotactic properties of angiopoitin-1 and -2 ligands for the endothelial-specific receptor tyrosine kinase Tie2
10. Angiopoietin-1 is an apoptosis survival factor for endothelial cells
11. Cell type-specific expression of angiopoietin-1 and angiopoietin-2 suggests a role in glioblastoma angiogenesis
12. Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma
13. In situ expression of angiopoietins in astrocytomas identifies angiopoietin-2 as an early marker of tumor angiogenesis
14. Vessel cooption, regression, and growth in tumors mediated by agiopoietins and VEGF
15. Organ-specific modulation of steady-state mdr-1 gene expression and drug resistance in murine colon cancer cells
16. Down-regulation of vascular endothelial growth factor in human colon carcinoma cell lines by antisense transfection decreases endothelial cell proliferation
17. Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastases
18. Tie 2 expression and phosphorylation in angiogenic and quiescent adult tissues
19. Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/Survivin pathway