Trapping prion protein in the endoplasmic reticulum impairs PrPC maturation and prevents PrPSc accumulation

Journal of Biological Chemistry

Volumn 280, Issue 1, 2005, Pages 685-694

  Cardinale, Alessio ^a   Filesi, Ilaria ^a   Vetrugno, Vito ^b   Pocchiari, Maurizio ^b   Sy, Man Sun ^c   Biocca, Silvia ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; CELLS; DISEASES; PRASEODYMIUM COMPOUNDS; SYNTHESIS (CHEMICAL);

CELL SURFACE; MATURATION; PRION DISEASES; PRION PROTEINS;

PROTEINS;

NERVE GROWTH FACTOR; PRION PROTEIN; PROTEINASE K; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELLULAR DISTRIBUTION; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; PRION; PRION DISEASE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; PROTEIN TARGETING; PROTEIN TRANSPORT; SCRAPIE; SECRETORY CELL;

ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; ENDOPLASMIC RETICULUM; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; OLIGOPEPTIDES; PRION DISEASES; PROTEIN SORTING SIGNALS; PRPC PROTEINS; PRPSC PROTEINS; RATS; RECOMBINANT PROTEINS;

EID: 12844260131     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M407360200     Document Type: Article

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