메뉴 건너뛰기




Volumn 24, Issue 3-4, 2003, Pages 623-632

Human calcitonin delivered orally by means of nanoparticles composed of novel graft copolymers

Author keywords

Graft copolymer; Human calcitonin; Nanoparticle; Oral delivery; Peptide

Indexed keywords

ABSORPTION; CARBOXYLIC ACIDS; COPOLYMERS; HYDROPHILICITY; POLYSTYRENES; POSITIVE IONS; STRUCTURE (COMPOSITION);

EID: 12444344758     PISSN: 01932691     EISSN: None     Source Type: Journal    
DOI: 10.1081/DIS-120021819     Document Type: Article
Times cited : (3)

References (38)
  • 2
    • 0024836302 scopus 로고
    • Penetration and enzymatic barriers to peptide and protein absorption
    • Lee, V.H.L.; Yamamoto, A. Penetration and enzymatic barriers to peptide and protein absorption. Adv. Drug Deliv. Rev. 1990, 4, 171-207.
    • (1990) Adv. Drug Deliv. Rev. , vol.4 , pp. 171-207
    • Lee, V.H.L.1    Yamamoto, A.2
  • 3
    • 0031563893 scopus 로고    scopus 로고
    • Rectal drug delivery systems: Improvement of rectal peptide absorption by absorption enhancers, protease inhibitors and chemical modification
    • Yamamoto, A.; Muranishi, S. Rectal drug delivery systems: improvement of rectal peptide absorption by absorption enhancers, protease inhibitors and chemical modification. Adv. Drug Deliv. Rev. 1997, 28, 275-299.
    • (1997) Adv. Drug Deliv. Rev. , vol.28 , pp. 275-299
    • Yamamoto, A.1    Muranishi, S.2
  • 4
    • 0027793362 scopus 로고
    • Clinical opportunities provided by the nasal administration of peptides
    • Harris, A.S. Clinical opportunities provided by the nasal administration of peptides. Drug Targeting 1993, 1, 101-116.
    • (1993) Drug Targeting , vol.1 , pp. 101-116
    • Harris, A.S.1
  • 5
    • 0030039663 scopus 로고    scopus 로고
    • Improvement of intestinal absorption of human calcitonin by chemical modification with fatty acid: Synergistic effects of acylation and absorption enhancers
    • Fujita, T.; Fujita, T.; Morikawa, K.; Tanaka, H.; lemura, O.; Yamamoto, A.; Muranishi, S. Improvement of intestinal absorption of human calcitonin by chemical modification with fatty acid: synergistic effects of acylation and absorption enhancers. Int. J. Pharm. 1996, 134, 47-57.
    • (1996) Int. J. Pharm. , vol.134 , pp. 47-57
    • Fujita, T.1    Fujita, T.2    Morikawa, K.3    Tanaka, H.4    Lemura, O.5    Yamamoto, A.6    Muranishi, S.7
  • 6
    • 0025113804 scopus 로고
    • Protease inhibitors and penetration enhancers as approaches to modify peptide absorption
    • Lee, V.H.L. Protease inhibitors and penetration enhancers as approaches to modify peptide absorption. J. Control. Rel. 1990, 13, 213-233.
    • (1990) J. Control. Rel. , vol.13 , pp. 213-233
    • Lee, V.H.L.1
  • 7
    • 0022468493 scopus 로고
    • A new approach to the oral administration of insulin and other peptide drugs
    • Saffran, M.; Kumar, G.S.; Savariar, C.; Burnham, J.C.; Williams, F.; Neckers, D.C. A new approach to the oral administration of insulin and other peptide drugs. Science 1986, 233, 1081-1084.
    • (1986) Science , vol.233 , pp. 1081-1084
    • Saffran, M.1    Kumar, G.S.2    Savariar, C.3    Burnham, J.C.4    Williams, F.5    Neckers, D.C.6
  • 8
    • 0035839271 scopus 로고    scopus 로고
    • Biorecognizable HPMA copolymer-drug conjugates for colon-specific delivery of 9-aminocamptothecin
    • Sakuma, S.; Lu, Z.R.; Kopečková, P.; Kopeček, J. Biorecognizable HPMA copolymer-drug conjugates for colon-specific delivery of 9-aminocamptothecin. J. Control. Rel. 2001, 75, 365-379.
    • (2001) J. Control. Rel. , vol.75 , pp. 365-379
    • Sakuma, S.1    Lu, Z.R.2    Kopečková, P.3    Kopeček, J.4
  • 9
    • 0023917757 scopus 로고
    • Binding of acrylic polymers to mucin/epithelial surfaces: structure-property relationships
    • Gu, J.P.; Robinson, J.R.; Leung, S.H.S. Binding of acrylic polymers to mucin/epithelial surfaces: structure-property relationships. Crit. Rev. Ther. Drug Carrier Syst. 1988, 5, 21-67.
    • (1988) Crit. Rev. Ther. Drug Carrier Syst. , vol.5 , pp. 21-67
    • Gu, J.P.1    Robinson, J.R.2    Leung, S.H.S.3
  • 10
    • 0035937594 scopus 로고    scopus 로고
    • Mucoadhesive nanoparticulate systems for peptide drug delivery
    • Takeuchi, H.; Yamamoto, H.; Kawashima, Y. Mucoadhesive nanoparticulate systems for peptide drug delivery. Adv. Drug Deliv. Rev. 2001, 47, 39-37.
    • (2001) Adv. Drug Deliv. Rev. , vol.47 , pp. 37-39
    • Takeuchi, H.1    Yamamoto, H.2    Kawashima, Y.3
  • 11
    • 0026186291 scopus 로고
    • Peroral administration of nanoparticles
    • Kreuter, J. Peroral administration of nanoparticles. Adv. Drug Deliv. Rev. 1991, 7, 71-86.
    • (1991) Adv. Drug Deliv. Rev. , vol.7 , pp. 71-86
    • Kreuter, J.1
  • 12
    • 0027590737 scopus 로고
    • Nano- and microparticles for the delivery of polypeptides and proteins
    • Couvreur, P.; Puisieux, F. Nano- and microparticles for the delivery of polypeptides and proteins. Adv. Drug Deliv. Rev. 1993, 10, 141-162.
    • (1993) Adv. Drug Deliv. Rev. , vol.10 , pp. 141-162
    • Couvreur, P.1    Puisieux, F.2
  • 13
    • 0030895036 scopus 로고    scopus 로고
    • Oral peptide delivery using nanoparticles composed of novel graft copolymers having hydrophobic backbone and hydrophilic branches
    • Sakuma, S.; Suzuki, N.; Kikuchi, H.; Hiwatari, K.; Arikawa, K.; Kishida, A.; Akashi, M. Oral peptide delivery using nanoparticles composed of novel graft copolymers having hydrophobic backbone and hydrophilic branches. Int. J. Pharm. 1997, 149, 93-106.
    • (1997) Int. J. Pharm. , vol.149 , pp. 93-106
    • Sakuma, S.1    Suzuki, N.2    Kikuchi, H.3    Hiwatari, K.4    Arikawa, K.5    Kishida, A.6    Akashi, M.7
  • 14
    • 0030734176 scopus 로고    scopus 로고
    • Absorption enhancement of orally administered salmon calcitonin by polystyrene nanoparticles having poly(N-isopropylacrylamide) branches on their surfaces
    • Sakuma, S.; Suzuki, N.; Kikuchi, H.; Hiwatari, K.; Arikawa, K.; Kishida, A.; Akashi, M. Absorption enhancement of orally administered salmon calcitonin by polystyrene nanoparticles having poly(N-isopropylacrylamide) branches on their surfaces. Int. J. Pharm. 1997, 158, 69-78.
    • (1997) Int. J. Pharm. , vol.158 , pp. 69-78
    • Sakuma, S.1    Suzuki, N.2    Kikuchi, H.3    Hiwatari, K.4    Arikawa, K.5    Kishida, A.6    Akashi, M.7
  • 15
    • 0031574414 scopus 로고    scopus 로고
    • Stabilization of salmon calcitonin by polystyrene nanoparticles having surface hydrophilic polymeric chains, against enzymatic degradation
    • Sakuma, S.; Ishida, Y.; Sudo, R.; Suzuki, N.; Kikuchi, H.; Hiwatari, K.; Kishida, A.; Akashi, M.; Hayashi, M. Stabilization of salmon calcitonin by polystyrene nanoparticles having surface hydrophilic polymeric chains, against enzymatic degradation Int. J. Pharm. 1997, 159, 181-189.
    • (1997) Int. J. Pharm. , vol.159 , pp. 181-189
    • Sakuma, S.1    Ishida, Y.2    Sudo, R.3    Suzuki, N.4    Kikuchi, H.5    Hiwatari, K.6    Kishida, A.7    Akashi, M.8    Hayashi, M.9
  • 16
    • 0032969652 scopus 로고    scopus 로고
    • Muco-adhesion of polystyrene nanoparticles having surface hydrophilic polymeric chains in the gastrointestinal tract
    • Sakuma, S.; Sudo, R.; Suzuki, N.; Kikuchi, H.; Hiwatari, K.; Akashi, M.; Hayashi, M. Muco-adhesion of polystyrene nanoparticles having surface hydrophilic polymeric chains in the gastrointestinal tract. Int. J. Pharm. 1999, 177, 161-172.
    • (1999) Int. J. Pharm. , vol.177 , pp. 161-172
    • Sakuma, S.1    Sudo, R.2    Suzuki, N.3    Kikuchi, H.4    Hiwatari, K.5    Akashi, M.6    Hayashi, M.7
  • 17
    • 0035937591 scopus 로고    scopus 로고
    • Design of nanoparticles composed of graft copolymers for oral peptide delivery
    • Sakuma, S.; Hayashi, M.; Akashi, M. Design of nanoparticles composed of graft copolymers for oral peptide delivery. Adv. Drug Deliv. Rev. 2001, 47, 21-37.
    • (2001) Adv. Drug Deliv. Rev. , vol.47 , pp. 21-37
    • Sakuma, S.1    Hayashi, M.2    Akashi, M.3
  • 18
    • 0037124540 scopus 로고    scopus 로고
    • Behavior of mucoadhesive nanoparticles having hydrophilic polymeric chains in the intestinal membrane
    • Sakuma, S.; Sudo, R.; Suzuki, N.; Kikuchi, H.; Akashi, M.; Ishida, Y.; Hayashi, M. Behavior of mucoadhesive nanoparticles having hydrophilic polymeric chains in the intestinal membrane J. Control. Rel. 2002, 81, 282-290.
    • (2002) J. Control. Rel. , vol.81 , pp. 282-290
    • Sakuma, S.1    Sudo, R.2    Suzuki, N.3    Kikuchi, H.4    Akashi, M.5    Ishida, Y.6    Hayashi, M.7
  • 19
    • 0037018962 scopus 로고    scopus 로고
    • Optimized chemical structure of nanoparticles as carriers for oral delivery of salmon calcitonin
    • Sakuma, S.; Suzuki, N.; Sudo, R.; Hiwatari, K.; Kishida, A.; Akashi, M. Optimized chemical structure of nanoparticles as carriers for oral delivery of salmon calcitonin. Int. J. Pharm. 2002, 239, 185-195.
    • (2002) Int. J. Pharm. , vol.239 , pp. 185-195
    • Sakuma, S.1    Suzuki, N.2    Sudo, R.3    Hiwatari, K.4    Kishida, A.5    Akashi, M.6
  • 20
    • 84981939450 scopus 로고
    • Synthesis and polymerization of a styryl terminated oligovinylpyrrolidone macromonomer
    • Akashi, M.; Kirikihara, I.; Miyauchi, N. Synthesis and polymerization of a styryl terminated oligovinylpyrrolidone macromonomer. Angew. Macromol. Chem. 1985, 132, 81-89.
    • (1985) Angew. Macromol. Chem. , vol.132 , pp. 81-89
    • Akashi, M.1    Kirikihara, I.2    Miyauchi, N.3
  • 21
    • 0024731744 scopus 로고
    • Polymer drugs and polymeric srugs. II. Synthesis of water dispersible microspheres having 5-fluorouracil and theophylline using a water soluble macromonomer
    • Akashi, M.; Wada, M.; Yanase, S.; Miyauchi, N. Polymer drugs and polymeric srugs. II. Synthesis of water dispersible microspheres having 5-fluorouracil and theophylline using a water soluble macromonomer. J. Polym. Sci. Polym. Lett. 1989, 27, 377-380.
    • (1989) J. Polym. Sci. Polym. Lett. , vol.27 , pp. 377-380
    • Akashi, M.1    Wada, M.2    Yanase, S.3    Miyauchi, N.4
  • 22
    • 0025700620 scopus 로고
    • Graft copolymers having hydrophobic backbone and hydrophilic branches, V. Microspheres obtained by the copolymerization of poly(ethylene glycol) macromonomer with methyl methacrylate
    • Akashi, M.; Chao, D.; Yashima, E.; Miyauchi, N. Graft copolymers having hydrophobic backbone and hydrophilic branches, V. Microspheres obtained by the copolymerization of poly(ethylene glycol) macromonomer with methyl methacrylate. J. Appl. Polym. Sci. 1990, 39, 2027-2030.
    • (1990) J. Appl. Polym. Sci. , vol.39 , pp. 2027-2030
    • Akashi, M.1    Chao, D.2    Yashima, E.3    Miyauchi, N.4
  • 23
    • 0024731447 scopus 로고
    • Graft copolymers having hydrophobic backbone and hydrophilic branches IV. A copolymerization study of water-soluble oligovinylpyrrolidone macromonomers
    • Akashi, M.; Yanagi, T.; Yashima, E.; Miyauchi, N. Graft copolymers having hydrophobic backbone and hydrophilic branches IV. A copolymerization study of water-soluble oligovinylpyrrolidone macromonomers. J. Polym. Sci. Polym. Chem. 1989, 27, 3521-3530.
    • (1989) J. Polym. Sci. Polym. Chem. , vol.27 , pp. 3521-3530
    • Akashi, M.1    Yanagi, T.2    Yashima, E.3    Miyauchi, N.4
  • 24
    • 0004355049 scopus 로고
    • On the kinetics of free radical polymerization of macromonomers
    • Capek, I.; Akashi, M. On the kinetics of free radical polymerization of macromonomers. J. Macromol. Sci.-Rev. Macromol. Chem. Phys. 1993, C33, 369-436.
    • (1993) J. Macromol. Sci.-Rev. Macromol. Chem. Phys. , vol.33 C , pp. 369-436
    • Capek, I.1    Akashi, M.2
  • 25
    • 0028869897 scopus 로고
    • High expression of a recombinant human calcitonin precursor peptide in escherichia coli
    • Yabuta, M.; Suzuki, Y.; Ohsuye, K. High expression of a recombinant human calcitonin precursor peptide in escherichia coli. Appl. Microbiol. Biotechnol. 1995, 42, 703-708.
    • (1995) Appl. Microbiol. Biotechnol. , vol.42 , pp. 703-708
    • Yabuta, M.1    Suzuki, Y.2    Ohsuye, K.3
  • 27
    • 0000861332 scopus 로고
    • Graft copolymers having a hydrophobic backbone and hydrophilic branches. IX. Preparation of water-dispersible microspheres having polycationic branches on their surfaces
    • Riza, M.; Tokura, S.; Kishida, A.; Akashi, M. Graft copolymers having a hydrophobic backbone and hydrophilic branches. IX. Preparation of water-dispersible microspheres having polycationic branches on their surfaces. N. Polym. Mater. 1994, 4, 189-198.
    • (1994) N. Polym. Mater. , vol.4 , pp. 189-198
    • Riza, M.1    Tokura, S.2    Kishida, A.3    Akashi, M.4
  • 28
    • 84989758344 scopus 로고
    • Graft copolymers having hydrophobic backbone and hydrophilic branches. X. Preparation and properties of water-dispersible poly-anionic microspheres having poly(methacrylic acid) branches on their surfaces
    • Riza, M.; Tokura, S.; Iwasaki, M.; Yashima, E.; Kishida, A.; Akashi, M. Graft copolymers having hydrophobic backbone and hydrophilic branches. X. Preparation and properties of water-dispersible poly-anionic microspheres having poly(methacrylic acid) branches on their surfaces. J. Polym. Sci. Polym. Chem. 1995, 33, 1219-1225.
    • (1995) J. Polym. Sci. Polym. Chem. , vol.33 , pp. 1219-1225
    • Riza, M.1    Tokura, S.2    Iwasaki, M.3    Yashima, E.4    Kishida, A.5    Akashi, M.6
  • 29
    • 0030217056 scopus 로고    scopus 로고
    • Graft copolymers having hydrophobic backbone and hydrophilic branches. XI. Preparation and thermo-sensitive properties of polystyrene microspheres having poly(N-isopropylacrylamide) branches on their surfaces
    • Chen, M.Q.; Kishida, A.; Akashi, M. Graft copolymers having hydrophobic backbone and hydrophilic branches. XI. Preparation and thermo-sensitive properties of polystyrene microspheres having poly(N-isopropylacrylamide) branches on their surfaces. J. Polym. Sci. Polym. Chem. 1996, 34, 2213-2220.
    • (1996) J. Polym. Sci. Polym. Chem. , vol.34 , pp. 2213-2220
    • Chen, M.Q.1    Kishida, A.2    Akashi, M.3
  • 30
    • 0032680088 scopus 로고    scopus 로고
    • Graft copolymers having hydrophobic backbone and hydrophilic branches. Polystyrene microspheres with poly(N-isopropylacrylamide) branches on their surfaces: Size control factors and thermosensitive behavior
    • Chen, M.Q.; Serizawa, T.; Akashi, M. Graft copolymers having hydrophobic backbone and hydrophilic branches. Polystyrene microspheres with poly(N-isopropylacrylamide) branches on their surfaces: size control factors and thermosensitive behavior. Polym. Adv. Tech. 1999, 10, 120-126.
    • (1999) Polym. Adv. Tech. , vol.10 , pp. 120-126
    • Chen, M.Q.1    Serizawa, T.2    Akashi, M.3
  • 32
    • 0023856501 scopus 로고
    • New approach for oral administration of insulin with polyalkylcyanoacrylate nanocapsules as drug carriers
    • Damgé, C.; Michel, C.; Aprahamian, M.; Couvreur, P. New approach for oral administration of insulin with polyalkylcyanoacrylate nanocapsules as drug carriers. Diabetes 1988, 37, 246-251.
    • (1988) Diabetes , vol.37 , pp. 246-251
    • Damgé, C.1    Michel, C.2    Aprahamian, M.3    Couvreur, P.4
  • 34
    • 0033969945 scopus 로고    scopus 로고
    • Mucoadhesive DL-lactide/glycolide copolymer nanospheres coated with chitosan to improve oral delivery of calcitonin
    • Kawashima, Y.; Yamamoto, H.; Takeuchi, H.; Kuno, Y. Mucoadhesive DL-lactide/glycolide copolymer nanospheres coated with chitosan to improve oral delivery of calcitonin. Pharm. Develop. and Technol. 2000, 5, 77-85.
    • (2000) Pharm. Develop. and Technol. , vol.5 , pp. 77-85
    • Kawashima, Y.1    Yamamoto, H.2    Takeuchi, H.3    Kuno, Y.4
  • 35
    • 0030453145 scopus 로고    scopus 로고
    • Mucoadhesive polymers in peroral peptide drug delivery. VI. Carbomer and chitosan improve the intestinal absorption of the peptide drug buserelin in vivo
    • Lueβen, H.L.; de Leeuw, B.J.; Langemeyer, M.W.E.; de Boer, A.G.; Verhoef, J.C.; Junginger, H.E. Mucoadhesive polymers in peroral peptide drug delivery. VI. Carbomer and chitosan improve the intestinal absorption of the peptide drug buserelin in vivo. Pharm. Res. 1996, 13, 1668-1672.
    • (1996) Pharm. Res. , vol.13 , pp. 1668-1672
    • Lueßen, H.L.1    de Leeuw, B.J.2    Langemeyer, M.W.E.3    de Boer, A.G.4    Verhoef, J.C.5    Junginger, H.E.6
  • 36
    • 0033991816 scopus 로고    scopus 로고
    • Chitosan and its derivatives: Potential excipients for peroral peptide delivery systems
    • Bernkop-Schnurch, A. Chitosan and its derivatives: potential excipients for peroral peptide delivery systems. Int. J. Pharm. 2000, 194, 1-13.
    • (2000) Int. J. Pharm. , vol.194 , pp. 1-13
    • Bernkop-Schnurch, A.1
  • 37
    • 0033972908 scopus 로고    scopus 로고
    • Oral bisphosphonates: A review of clinical use in patients with bone metastases
    • Major, P.P.; Lipton, A.; Berenson, J.; Hortobagyi, G. Oral bisphosphonates: a review of clinical use in patients with bone metastases. Cancer 2000, 88, 6-14.
    • (2000) Cancer , vol.88 , pp. 6-14
    • Major, P.P.1    Lipton, A.2    Berenson, J.3    Hortobagyi, G.4
  • 38
    • 0035806258 scopus 로고    scopus 로고
    • Mode of administration-dependent pharmacokinetics of bisphosphonates and bioavailability determination
    • Hoffman, A.; Stepensky, D.; Ezra, A.; Van Gelder, J.M.; Golomb, G. Mode of administration-dependent pharmacokinetics of bisphosphonates and bioavailability determination. Int. J. Pharm. 2001, 220, 1-11.
    • (2001) Int. J. Pharm. , vol.220 , pp. 1-11
    • Hoffman, A.1    Stepensky, D.2    Ezra, A.3    Van Gelder, J.M.4    Golomb, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.