Oral peptide delivery using nanoparticles composed of novel graft copolymers having hydrophobic backbone and hydrophilic branches

International Journal of Pharmaceutics

Volumn 149, Issue 1, 1997, Pages 93-106

  Sakuma, Shinji ^a   Suzuki, Norio ^a   Kikuchi, Hiroshi ^a   Hiwatari, Ken Ichiro ^b   Arikawa, Kiyotaka ^b   Kishida, Akio ^b   Akashi, Mitsuru ^b  

^a DAIICHI SANKYO CO   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Absorption enhancement; Graft copolymer; Macromonomer; Nanoparticle; Peptide; Poly(N isopropylacrylamide)

Indexed keywords

COPOLYMER; DRUG CARRIER; NANOPARTICLE; POLYMETHACRYLIC ACID; SALCATONIN;

ANIMAL EXPERIMENT; ARTICLE; DRUG DELIVERY SYSTEM; HYDROLYSIS; HYPOCALCEMIA; MALE; NONHUMAN; OLIGOMERIZATION; ORAL DRUG ADMINISTRATION; PARTICLE SIZE; PHASE TRANSITION; PRIORITY JOURNAL; RAT;

EID: 0030895036     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(96)04861-2     Document Type: Article

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