Biorecognizable HPMA copolymer-drug conjugates for colon-specific delivery of 9-aminocamptothecin

Journal of Controlled Release

Volumn 75, Issue 3, 2001, Pages 365-379

  Sakuma, Shinji ^a   Lu, Zheng Rong ^a   Kopečková, Pavla ^a,b   Kopeček, Jindřich ^a,b  

^a UNIVERSITY OF UTAH   (United States)

^b Department of Electrical and Computer Engineering   (United States)

Author keywords

Anticancer drug; Camptothecin; Colon specific drug delivery; Drug release; N (2 Hydroxypropyl)methacrylamide (HPMA) copolymer

Indexed keywords

9 AMINOCAMPTOTHECIN N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER; ALANINE; ALANINE DERIVATIVE; AZO COMPOUND; AZO REDUCTASE; DNA TOPOISOMERASE INHIBITOR; INTESTINE ENZYME; LEUCYLALANINE; PEPTIDASE; PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CHEMICAL STRUCTURE; COLON; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG SCREENING; ENZYME ACTIVITY; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; CAMPTOTHECIN; COLON; MALE; METHACRYLATES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0035839271     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00405-9     Document Type: Article

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