Nuclear localisation sequence templated nonviral gene delivery vectors: Investigation of intracellular trafficking events of LMD and LD vector systems

ChemBioChem

Volumn 4, Issue 4, 2003, Pages 286-298

  Keller, Michael ^a   Harbottle, Richard P ^b   Perouzel, Eric ^a   Colin, Morvane ^d   Shah, Imran ^c   Rahim, Abad ^b   Vaysse, Laurence ^b   Bergau, Anna ^b   Moritz, Sylviane ^d   Brahimi Horn, Christiane ^d   Coutelle, Charles ^b   Miller, Andrew D ^c  

^a IC Vec Ltd   (United Kingdom)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d INSERM   (France)

Author keywords

Gene technology; Gene therapy; Lipids; Nuclear localisation sequence; Peptides

Indexed keywords

3BETA [N (N',N DIMETHYLAMINOETHANE)CARBAMOYL]CHOLESTEROL DIOLEOYL ALPHA PHOSPHATIDYLETHANOLAMINE; ADNEOVIRUS CORE PEPTIDE MU; CATION; FLUORESCEIN POLYETHYLENE GLYCOL N HYDROXYSUCCINIMIDE; HYBRID PROTEIN; LIPID; LIPOSOME; MACROGOL; MU BETA GALACTOSIDASE FUSION PROTEIN; PEPTIDE; PHOSPHATIDYLETHANOLAMINE; PLASMID DNA; SUCCINIMIDE DERIVATIVE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ADENOVIRUS; ARTICLE; CELL CYCLE S PHASE; CELL DIVISION; CELL GROWTH; CELL LABELING; CELL NUCLEUS; CONFOCAL MICROSCOPY; CYTOSOLIC FRACTION; DNA DETERMINATION; DNA TRANSFER; DRUG DNA BINDING; FLUORESCENCE; GENE DELIVERY SYSTEM; GENE TECHNOLOGY; GENE THERAPY; GROWTH INHIBITION; INCUBATION TIME; INTRACELLULAR TRANSPORT; LD NONVIRAL GENE DELIVERY SYSTEM; LIPID ANALYSIS; LMD NONVIRAL GENE DELIVERY SYSTEM; MATERIAL COATING; MOLECULAR CLONING; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NUCLEAR LOCALIZATION SIGNAL; NUCLEOLUS; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SIMIAN VIRUS 40; STEALTH SYSTEM;

ADENOVIRIDAE; CARBOCYANINES; CELL LINE; CHOLESTEROL; DNA; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FLUORESCENT DYES; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GLYCOSIDE HYDROLASES; HUMANS; INTRACELLULAR SPACE; LIPOSOMES; MICROSCOPY, CONFOCAL; NUCLEAR LOCALIZATION SIGNALS; OLIGOPEPTIDES; PEPTIDES; PHOSPHATIDYLETHANOLAMINES; PLASMIDS; POLYETHYLENE GLYCOLS; RECOMBINANT FUSION PROTEINS; TRANSFECTION;

ADENOVIRIDAE; SIMIAE; SIMIAN VIRUS 40;

EID: 12444339877     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbic.200390049     Document Type: Article

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