Lipids, lipid domains and lipid-protein interactions in endocytic membrane traffic

Seminars in Cell and Developmental Biology

Volumn 9, Issue 5, 1998, Pages 517-526

  Kobayashi, Toshihide ^b   Gu, Feng ^b   Gruenberg, Jean ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b NONE

Author keywords

Endosome; Lipid domain; Membrane dynamics; Sorting; Traffic

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR; ANNEXIN; CHOLESTEROL; EARLY ENDOSOME ANTIGEN 1; GLYCOSPHINGOLIPID; GUANINE NUCLEOTIDE BINDING PROTEIN; LYSOBISPHOSPHATIDIC ACID; LYSOPHOSPHOLIPID; MEMBRANE LIPID; MEMBRANE PROTEIN; MONOACYLGLYCEROL; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE D; VESICULAR TRANSPORT PROTEIN;

ANIMAL; CHEMISTRY; ENDOCYTOSIS; ENDOSOME; EUKARYOTIC CELL; INTRACELLULAR MEMBRANE; MACROMOLECULE; PHYSIOLOGY; REVIEW;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADP-RIBOSYLATION FACTORS; ANIMALS; ANNEXINS; CHOLESTEROL; ENDOCYTOSIS; ENDOSOMES; EUKARYOTIC CELLS; GLYCOSPHINGOLIPIDS; GTP-BINDING PROTEINS; INTRACELLULAR MEMBRANES; LYSOPHOSPHOLIPIDS; MACROMOLECULAR SUBSTANCES; MEMBRANE LIPIDS; MEMBRANE PROTEINS; MONOGLYCERIDES; PHOSPHATIDYLINOSITOLS; PHOSPHOLIPASE D; VESICULAR TRANSPORT PROTEINS;

EID: 0032174579     PISSN: 10849521     EISSN: None     Source Type: Journal    
DOI: 10.1006/scdb.1998.0257     Document Type: Article

References (133)

1. Gruenberg J, Maxfield F (1995) Membrane transport in the endocytic pathway. Curr Opin Cell Biol 7:552-563
2. Mellman I (1996) Endocytosis and molecular sorting. Ann Rev Cell Develop Biol 12:575-626
3. Yamashiro DJ, Tycko B, Fluss SR, Maxfield FR (1984) Segregation of transferrin to a mildly acidic (pH 6.4) para-Golgi compartment in the recycling pathway. Cell 37:789-800
4. Riezman H, Woodman PG, vanMeer G, Marsh M (1997) Molecular mechanisms of endocytosis. Cell 91:731-738
5. Kornfeld S (1992) Structure and function of the mannose 6-phosphate/insulin-like growth factor II receptors. Annu Rev Biochem 61:307-330
6. Cowles CR, Odorizzi G, Payne GS, Emr SD (1997). The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole. Cell 91:109-118
7. Kantheti P, Qiao X, Diaz ME, Peden AA, Meyer GE, Carskadon SL, Kapfhamer D, Sufalko D, Robinson MS, Noebels JL, Burmeister M (1998) Mutation in AP-3 delta in the mocha mouse links endosomal transport to storage deficiency in platelets, melanosomes, and synaptic vesicles. Neuron 21:111-122
8. Simpson F, Peden AA, Christopoulou L, Robinson MS (1997) Characterization of the adaptor-related protein complex, AP-3. J Cell Biol 137:835-845
9. Devaux PF (1991) Static and dynamic lipid asymmetry in cell membranes. Biochemistry 30:1163-1173
10. Emoto K, Kobayashi T, Yamaji A, Aizawa H, Yahara I, Inoue K, Umeda M (1996) Redistribution of phosphatidylethanolamine at the cleavage furrow of dividing cells during cytokinesis. Proc Natl Acad Sci USA 93:12867-12872
11. Op den Kamp JA (1979) Lipid asymmetry in membranes. Annu Rev Biochem 48:47-71
12. Evans WH, Hardison WG (1985) Phospholipid, cholesterol, polypeptide and glycoprotein composition of hepatic endosome subfractions. Biochem J 232:33-36
13. Hornick CA, Hui DY, DeLamatre JG (1997) A role for retrosomes in intracellular cholesterol transport from endosomes to the plasma membrane. Am J Physiol 273:C1075-1081
14. Kobayashi T, Stang E, Fang KS, de Moerloose P, Parton RG, Gruenberg J (1998) A lipid associated with the antiphospholipid syndrome regulates endosome structure and function. Nature 392:193-197
15. Brotherus J, Renkonen O (1977) Subcellular distributions of lipids in cultured BHK cells: evidence for the enrichment of lysobisphosphatidic acid and neutral lipids in lysosomes. J Lipid Res 18:191-202
16. Wherrett JR, Huterer S (1972) Enrichment of bis-(monoacylglyceryl) phosphate in lysosomes from rat liver. J Biol Chem 247:4114-4120
17. Brotherus J, Renkonen O, Fischer W, Herrmann J (1974) Novel stereoconfiguration in lyso-bis-phosphatidic acid of cultured BHK-cells. Chem Phys Lipids 13:178-182
18. Amidon B, Brown A, Waite M (1996) Transacylase and phospholipases in the synthesis of bis(monoacylglycero)phosphate. Biochemistry 35:13995-14002
19. Dunn WA, Jr (1990) Studies on the mechanisms of autophagy: formation of the autophagic vacuole. J Cell Biol 110:1923-1933
20. Hoyvik H, Gordon PB, Berg TO, Seglen PO (1991) Inhibition of autophagic-lysosomal delivery and autophagic lactolysis by asparagine. J. Cell Biol 113:1305-1312
21. Tooze J, Hollinshead M, Ludwig T, Howell, Hoflack B, Kern H (1990) In exocrine pancreas, the basolateral endocytic pathway converges with the autophagic pathway immediately after the early endosome. J Cell Biol 111:329-345
22. Brotherus J, Niinioja T, Sandelin K, Renkonen O (1977) Experimentally caused proliferation of lysosomes in cultured BHK cells involving an increase of biphosphatidic acids and triglycerides. J Lipid Res 18:379-388
23. Somerharju P, Brotherus J, Kahma K, Renkonen O (1977) Stereoconfiguration of bisphosphatidic and semilysobisphosphatidic acids from cultured hamster fibroblasts (BHK cells). Biochim Biophys Acta 487:154-162
24. Somerharju P (1979) Subcellular localization of three degeneration-associated phospholipids in cultured hamster fibroblasts (BHK21 cells). Biochim Biophys Acta 574:461-470
25. Cluett EB, Kuismanen E, Machamer CE (1997). Heterogeneous distribution of the unusual phospholipid semilysobis-phosphatidic acid through the Golgi complex. Mol Biol Cell 8:2233-2240
26. Cluett EB, Machamer CE (1996) The envelope of vaccinia virus reveals an unusual phospholipid in Golgi complex membranes. J Cell Sci 109:2121-2131
27. Sandvig K, van Deurs B (1996) Endocytosis, intracellular transport, and cytotoxic action of Shiga toxin and ricin. Physiol Rev 76:949-966
28. Hoekstra D, Kok JW (1992) Trafficking of glycosphingolipids in eukaryotic cells; sorting and recycling of lipids. Biochim Biophys Acta 1113:277-294
29. Rosenwald AG, Pagano RE (1993) Intracellular transport of ceramide and its metabolites at the Golgi complex: insights from short-chain analogs. Adv Lipid Res 26:101-118
30. Endo TA, Kobayashi T, Ohki K (1996) A Chinese hamster ovary cell mutant resistant to phosphatidylserine is defective in transbilayer movement of cell surface phosphatidylserine. Exp Cell Res 228:341-346
31. Hanada K, Pagano RE (1995) A Chinese hamster ovary cell mutant defective in the non-endocytic uptake of fluorescent analogs of phosphatidylserine: isolation using a cytosol acidification protocol. J Cell Biol 128:793-804
32. Martin OC, Pagano RE (1987) Transbilayer movement of fluorescent analogs of phosphatidylserine and phosphatidylethanolamine at the plasma membrane of cultured cells. Evidence for a protein-mediated and ATP-dependent process(es). J Biol Chem 262:5890-5898
33. Pomorski T, Muller P, Zimmermann B, Burger K, Devaux PF, Herrmann A (1996) Transbilayer movement of fluorescent and spin-labeled phospholipids in the plasma membrane of human fibroblasts: a quantitative approach. J Cell Sci 109:687-698
34. Kobayashi T, Arakawa Y (1991) Transport of exogenous fluorescent phosphatidylserine analogue to the Golgi apparatus in cultured fibroblasts. J Cell Biol 113:235-244
35. Kok JW, Babia T, Hoekstra D (1991). Sorting of sphingolipids in the endocytic pathway of HT29 cells. J Cell Biol 114:231-239
36. Kok JW, Eskelinen S, Hoekstra K, Hoekstra D (1989) Salvage of glucosylceramide by recycling after internalization along the pathway of receptor-mediated endocytosis. Proc Natl Acad Sci USA 86:9896-9900
37. Koval M, Pagano RE (1989) Lipid recycling between the plasma membrane and intracellular compartments: transport and metabolism of fluorescent sphingomyelin analogues in cultured fibroblasts. J Cell Biol 108:2169-2181
38. Koval M, Pagano RE (1990) Sorting of an internalized plasma membrane lipid between recycling and degradative pathways in normal and Niemann-Pick, type A fibroblasts. J Cell Biol 111:429-442
39. Mayor S, Presley JF, Maxfield FR (1993) Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process. J Cell Biol 121:, 1257-1269
40. van IJzendoorn SC, Zegers MM, Kok JW, Hoekstra D (1997) Segregation of glucosylceramide and sphingomyelin occurs in the apical to basolateral transcytotic route in HepG2 cells. J Cell Biol 137:347-357
41. van IJzendoorn SCD, Hoekstra D (1998) (Glyco)sphingolipids are sorted in sub-apical compartments in HepG2 cells: a role for non-Golgi-related intracellular sites in the polarized distribution of (glyco)sphingolipids. J Cell Biol 142:683-696
42. Apodaca G, Katz LA, Mostov KE (1994) Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes. J Cell Biol 125:67-86
43. Odorizzi G, Pearse A, Domingo D, Trowbridge IS, Hopkins CR (1996) Apical and basolateral endosomes of MDCK cells are interconnected and contain a polarized sorting mechanism. J Cell Biol 135:139-152
44. Barroso M, Sztul ES (1994) Basolateral to apical transcytosis in polarized cells is indirect and involves BFA and trimeric G protein sensitive passage through the apical endosome. J Cell Biol 124:83-100
45. Parton RG (1996) Caveolae and caveolins. Curr Opin Cell Biol 8:542-548
46. Parton RG, Way M, Zorzi N, Stang E (1997) Caveolin-3 asssociates with T-tubules during muscle development. J Cell Biol 136:137-154
47. Simons K, Ikonen E (1997) Functional rafts in cell membranes. Nature 387:569-572
48. Mayor S, Sabharanjak S, Maxfield FR (1998) Cholesterol-dependent retention of GPI-anchored proteins in endosomes. Embo J 17:4626-4638
49. Harder T, Kellner R, Parton R, Gruenberg J (1997) Specific release of membrane bound annexin II and cortical cytoskeletal elements by sequestration of membrane cholesterol. Mol Biol Cell 8:533-545
50. Dunn WA, Connolly TP, Hubbard AL (1986) Receptor-mediated endocytosis of epidermal growth factor by rat hepatocytes: receptor pathway. J Cell Biol 102:24-36
51. Geuze HJ, Slot JW, Strous GJ, Lodish HF, Schwartz AL (1983) Intracellular site of asialoglycoprotein receptor-ligand uncoupling: double-label immunoelectron microscopy during receptor-mediated endocytosis. Cell 32:277-287
52. Gruenberg J, Griffiths G, Howell KE (1989) Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro. J Cell Biol 108:1301-1316
53. Gu F, Aniento F, Parton RG, GruenbergJ (1997) Functional dissection of COP-I subunits in the biogenesis of multivesicular endosomes. J Cell Biol 139:1183-1195
54. Hopkins CR (1983) The importance of the endosome in intracellular traffic. Nature 304:684-685
55. McDowall A, Gruenberg J, Romisch K, Griffiths G (1989). The structure of organelles of the endocytic pathway in hydrated cryosections of cultured cells. Eur J Cell Biol 49:281-294
56. van Deurs B, Holm PK, Kayser L, Sandvig K, Hansen SH (1993) Multivesicular bodies in HEp-2 cells are maturing endosomes. Eur J Cell Biol 61:208-224
57. Clague M, Urbé S, Aniento F, Gruenberg J (1994) Vacuolar ATPase activity is required for endosomal carrier vesicle formation. J Biol Chem 269:21-24
58. Aniento F, Gu F, Parton RG, GruenbergJ (1996) An endosomal beta COP is involved in the pH-dependent formation of transport vesicles destined for late endosomes. J Cell Biol 133:29-41
59. Daro E, Sheff D, Gomez M, Kreis T, Mellman I (1997) Inhibition of endosome function in CHO cells bearing a temperature-sensitive defect in the coatomer (COPI) component epsilon-COP. J Cell Biol 139:1747-1759
60. Whitney JA, Gomez M, Sheff D, Kreis TE, Mellman I (1995) Cytoplasmic coat proteins involved in endosome function. Cell 83:703-713
61. Kirchhausen T, Bonifacino JS, Riezman H (1997a). Linking cargo to vesicle formation: receptor tail interactions with coat proteins. Curr Opin Cell Biol 9:488-495
62. Benichou S, Bomsel M, Bodeus M, Durand H, Doute M, Letourneur F, Camonis J, Benarous R (1994) Physical interaction of the HIV-1 Nef protein with beta-COP, a component of non-clathrin-coated vesicles essential for membrane traffic. J Biol Chem 269:30073-30076
63. Hansen K, Ronnstrand L, Rorsman C, Hellman U, Heldin CH (1997) Association of coatomer proteins with the beta-receptor for platelet-derived growth factor. Biochem Biophys Res Commun 235:455-460
64. Felder S, Miller K, Moehren G, Ullrich A, Schlessinger J, Hopkins CR (1990) Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body. Cell 61:623-634
65. Green SA, Setiadi H, McEver RP, Kelly RB (1994) The cytoplasmic domain of P-selectin contains a sorting determinant that mediates rapid degradation in lysosomes. J Cell Biol 124:435-448
66. Aiken C, Konner J, Landau NR, Lenburg ME, Trono D (1994) Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain. Cell 76:853-864
67. Letourneur F, Klausner RD (1992) A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains. Cell 69:1143-1157
68. Reaves BJ, Banting G, Luzio JP (1998). Lumenal and transmembrane domains play a role in sorting type I membrane proteins on endocytic pathways. Mol Biol Cell 9:1107-1122
69. Rohrer J, Schweizer A, Russell D, Kornfeld S (1996) The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane. J Cell Biol 132:565-576
70. Presley JF, Mayor S, McGraw TE, Dunn KW, Maxfield FR (1997) Bafilomycin Al treatment retards transferrin receptor recycling more than bulk membrane recycling. J Biol Chem 272:13929-13936
71. Griffiths G, Hoflack B, Simons K, Mellman I, Kornfeld S (1988) The mannose 6-phosphate receptor and the biogenesis of lysosomes. Cell 52:329-341
72. Geuze HJ (1998) The role of endosomes and lysosomes in MHC class II functioning. Immunol Today 19:282-287
73. Escola JM, Kleijmeer MJ, Stoorvogel W, Griffith JM, Yoshie O, Geuze HJ (1998) Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes. J Biol Chem 273:20121-20127.
74. Maecker HT, Todd SC, Levy S (1997). The tetraspanin superfamily: molecular facilitators. Faseb J 11:428-442
75. Aniento F, Emans N, Griffiths G, Gruenberg J (1993) Cytoplasmic dynein-dependent vesicular transport from early to late endosomes. J Cell Biol 123:1373-1388
76. Toker A, Cantley LC (1997) Signalling through the lipid products of phosphoinositide-3-OH kinase. Nature 387:673-676
77. De Camilli P, Emr SD, McPherson PS, Novick P (1996) Phosphoinositides as regulators in membrane traffic. Science 271:1533-1539
78. Martin TF (1997). Phosphoinositides as spatial regulators of membrane traffic. Curr Opin Neurobiol 7:331-338
79. Joly M, Kazlauskas A, Corvera S (1995) Phosphatidylinositol 3-kinase activity is required at a postendocytic step in platelet-derived growth factor receptor trafficking. J Biol Chem 270:13225-13230
80. Shpetner H, Joly M, Hartley D, Corvera S (1996) Potential sites of PI-3 kinase function in the endocytic pathway revealed by the PI-3 kinase inhibitor, wortmannin. J Cell Biol 132:595-605
81. Cefai D, Schneider H, Matangkasombut O, Kang H, BrodyJ, Rudd CE (1998) CD28 receptor endocytosis is targeted by mutations that disrupt phosphatidylinositol 3-kinase binding and costimulation. J Immunol 160:2223-2230
82. Malide D, Cushman SW (1997) Morphological effects of wortmannin on the endosomal system and GLUT4-containing compartments in rat adipose cells. J Cell Sci 110:2795-2806
83. Clark SF, Martin S, Carozzi AJ, Hill MM, James DE (1998) Intracellular localization of phosphatidylinositide 3-kinase and insulin receptor substrate-1 in adipocytes: potential involvement of a membrane skeleton. J Cell Biol 140:1211-1225
84. Sorensen SD, Linseman DA, McEwen EL, Heacock AM, Fisher SK (1998) A role for a wortmannin-sensitive phosphatidylinositol-4-kinase in the endocytosis of muscarinic cholinergic receptors. Mol Pharmacol 53:827-836
85. Li G, D'Souza-Schorey C, Barbieri MA, Roberts RL, Klippel A, Williams LT, Stahl PD (1995) Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5. Proc Natl Acad Sci USA 92:10207-10211
86. Martys JL, Wjasow C, Gangi DM, Kielian MC, McGraw TE, Backer JM (1996) Wortmannin-sensitive trafficking pathways in Chinese hamster ovary cells. Differential effects on endocytosis and lysosomal sorting. J Biol Chem 271:10953-10962
87. Shepherd PR, Soos MA, Siddle K (1995) Inhibitors of phosphoinositide 3-kinase block exocytosis but not endocytosis of transferrin receptors in 3T3-L1 adipocytes. Biochem Biophys Res Commun 211:535-539
88. Spiro DJ, Boll W, Kirchhausen T, Wessling-Resnick M (1996) Wortmannin alters the transferrin receptor endocytic pathway in vivo and in vitro. Mol Biol Cell 7:355-367
89. Reaves BJ, Bright NA, Mullock BM, Luzio JP (1996) The effect of wortmannin on the localisation of lysosomal type I integral membrane glycoproteins suggests a role for phosphoinositide 3-kinase activity in regulating membrane traffic late in the endocytic pathway. J Cell SCi 109:749-762
90. Brown WJ, DeWald DB, Emr SD, Plutner H, Balch WE (1995) Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells. J Cell Biol 130:781-796
91. Davidson HW (1995) Wortmannin causes mistargeting of procathepsin D. evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes. J Cell Biol 130:797-805
92. Kundra R, Kornfeld S (1998) Wortmannin retards the movement of the mannose 6-phosphate/insulin-like growth factor II receptor and its ligand out of endosomes. J Biol Chem 273:3848-3853
93. Nakajima Y, Pfeffer SR (1997) Phosphatidylinositol 3-kinase is not required for recycling of mannose 6-phosphate receptors from late endosomes to the trans-Golgi network. Mol Biol Cell 8:577-582
94. McClure SJ, Robinson PJ (1996) Dynamin, endocytosis and intracellular signalling. Mol Mem Biol 13:189-215
95. Schmid SL (1997). Clathrin-coated vesicle formation and protein sorting: an integrated process. Annu Rev Biochem 66:511-548
96. McPherson PS, Garcia EP, Slepnev VI, David C, Zhang X, Grabs D, Sossin WS, Bauerfeind R, Nemoto Y, De Camilli P (1996) A presynaptic inositol-5-phosphatase. Nature 379:353-357
97. Mitchell CA, Brown S, Campbell JK, Munday AD, Speed CJ (1996) Regulation of second messengers by the inositol polyphosphate 5-phosphatases. Biochem Soc Trans 24:994-1000
98. Ahn SJ, Han SJ, Mo HJ, Chung J, Hong SH, Park TK, Kim CG (1998) Interaction of phospholipase C gamma 1 via its COOH-terminal SRC homology 2 domain with synaptojanin. Biochem Biophys Res Commun 244:62-67
99. Chung JK, Sekiya F, Kang HS, Lee C, Han JS, Kim SR, Bae YS, Morris AJ, Rhee SG (1997) Synaptojanin inhibition of phospholipase D activity by hydrolysis of phosphatidylinositol 4,5-bisphosphate. J Biol Chem 272:15980-15985
100. Urrutia R, Henley JR, Cook T, McNiven MA (1997) The dynamins: redundant or distinct functions for an expanding family of related GTPases? Proc Natl Acad Sci USA 94:377-384
101. Roth MG, Sternweis PC (1997). The role of lipid signaling in constitutive membrane traffic. Curr Opin Cell Biol 9:519-526
102. Sweitzer SM, Hinshaw JE (1998) Dynamin undergoes a GTP-dependent conformational change causing vesiculation. Cell 93:1021-1029
103. Takei K, Haucke V, Slepnev V, Farsad K, Salazar M, Chen H, De Camilli P (1998) Generation of coated intermediates of clathrin-mediated endocytosis on protein-free liposomes. Cell 94:131-141
104. Gaidarov I, Chen Q, Falck JR, Reddy KK, Keen JH (1996) A functional phosphatidylinositol 3,4,5-trisphosphate/phosphoinositide binding domain in the clathrin adaptor AP-2 alpha subunit. Implications for the endocytic pathway (published erratum appears in J Biol Chem 1996 Oct 25;271(43):27188). J Biol Chem 271:20922-9
105. Kirchhausen T, Bonifacino JS, Riezman H (1997b) Linking cargo to vesicle formation: receptor tail interactions with coat proteins. Curr Opin Cell Biol 9:488-495
106. Rapoport I, Miyazaki M, Boll W, Duckworth B, Cantley LC, Shoelson S, Kirchhausen T (1997) Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexes. Embo J 16:2240-2250
107. Rapoport I, Chen YC, Cupers P, Shoelson SE, Kirchhausen T (1998) Dileucine-based sorting signals bind to the beta chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding site. Embo J 17:2148-2155
108. Jones AT, Clague MJ (1995) Phosphatidylinositol 3-kinase activity is required for early endosome fusion. Biochem J 311:31-34
109. Gorvel JP, Chavrier P, Zerial M, Gruenberg J (1991) rab5 controls early endosome fusion in vitro. Cell 64:915-925
110. Patki V, Virbasius J, Lane WS, Toh BH, Shpetner HS, Corvera S (1997) Identification of an early endosomal protein regulated by phosphatidylinositol 3-kinase. Proc Natl Acad Sci USA 94:7326-3730
111. Gaullier JM, Simonsen A, D'Arrigo A, Bremnes B, Stenmark H, Aasland R (1998) FYVE fingers bind PtdIns(3)P. Nature 394:432-3
112. Patki V, Lawe DC, Corvera S, Virbasius JV, Chawla A (1998) A functional PtdIns(3)P-binding motif (letter). Nature 394:433-434
113. Mills IG, Jones AT, Clague MJ (1998) Involvement of the endosomal autoantigen EEA1 in homotypic fusion of early endosomes. Curr Biol 8:881-884
114. Simonsen A, Lippe R, ChristoforidisS, GaullierJM, Brech A, Callaghan J, Toh BH, Murphy C, Zerial M, Stenmark H (1998) EEA1 links PI(S)K function to Rab5 regulation of endosome fusion. Nature 394:494-498
115. Creutz CE (1992) The annexins and exocytosis. Science 258:924-931
116. Gerke V, Moss SE (1997) Annexins and membrane dynamics. Biochim Biophys Acta 1357:129-154
117. Gruenberg J, Emans N (1993) Annexins in membrane tranport. Trends Cell Biol 3:224-227
118. Futter CE, Felder S, Schlessinger J, Ullrich A, Hopkins C (1993) Annexin I is phosphorylated in the multivesicular body during the processing of the epidermal growth factor receptor. J Cell Biol 120:77-83
119. 2+ and requires an intact N-terminal domain. Mol Biol Cell 7:1359-1374
120. Emans N, Gorvel J-P, Walter C, Gerke V, Griffiths G, Gruenberg J (1993) Annexin II is a major component of fusogenic endosomal vesicles. J Cell Biol 120:1357-1370
121. Harder T, Gerke V (1993) The subcellular distribution of early endosomes is affected by the annexin II(2) p11(2) complex. J Cell Biol 123:1119-1132
122. Kreis TE, Lowe M, Pepperkok R (1995) COPs regulating membrane traffic. Annu Rev Cell Biol 11:677-706
123. Chardin P, Paris S, Antonny B, Robineau S, Beraud-Dufour S, Jackson CL, Chabre M (1996) A human exchange factor for ARF contains Sec7- and pleckstrin-homology domains. Nature 384:481-484
124. Chen YG, Siddhanta A, Austin CD, Hammond SM, Sung TC, Frohman MA, Morris AJ, Shields D (1997) Phospholipase D stimulates release of nascent secretory vesicles from the trans-Golgi network. J Cell Biol 138:495-504
125. West MA, Bright NA, Robinson MS (1997) The role of ADP-ribosylation factor and phospholipase D in adaptor recruitment. J Cell Biol 138:1239-1254
126. Stamnes MA, Rothman JE (1993) The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein. Cell 73:999-1005
127. Ooi CE, Dell'Angelica EC, Bonifacino JS (1998) ADP-Ribosylation factor 1 (ARF1) regulates recruitment of the AP-3 adaptor complex to membranes. J Cell Biol 142:391-402
128. Geuze HJ. Laboratory of Cell Biology, Medical School, Utrecht University, The Netherlands
129. Hammond SM, Altshuller YM, Sung TC, Rudge SA, Rose K, Engebrecht J, Morris AJ, Frohman MA (1995) Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family. J Biol Chem 270:29640-29643
130. Hao W, Tan Z, Prasad K, Reddy KK, Chen J, Prestwich GD, Falck JR, Shears SB, Lafer EM (1997) Regulation of AP-3 function by inositides. Identification of phosphatidylinositol 3,4,5-trisphosphate as a potent ligand. J Biol Chem 272:6393-6398
131. Paris S, Beraud-Dufour S, Robineau S, Bigay J, Antonny B, Chabre M, Chardin P (1997) Role of protein-phospholipid interactions in the activation of ARF1 by the guanine nucleotide exchange factor Arno. J Biol Chem 272: 22221-22226
132. Parton RG. Centre for Microscopy and Microanalysis. University of Queensland, Brisbane, Australia
133. Yokozeki T, Kuribara H, Katada T, Touhara K, Kanaho Y (1996) Partially purified RhoA-stimulated phospholipase D activity specifically binds to phosphatidylinositol 4,5-bisphosphate. J Neurochem 66:1234-1239