Novel, potent and selective cyclin D1/CDK4 inhibitors: Indolo[6,7-a]pyrrolo[3,4-c]carbazoles

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 14, 2003, Pages 2261-2267

  Engler, Thomas A ^a   Furness, Kelly ^a   Malhotra, Sushant ^a   Sanchez Martinez, Concha ^b   Shih, Chuan ^a   Xie, Walter ^a   Zhu, Guoxin ^a   Zhou, Xun ^a   Conner, Scott ^a   Faul, Margaret M ^a   Sullivan, Kevin A ^a   Kolis, Stanley P ^a   Brooks, Harold B ^a   Patel, Bharvin ^a   Schultz, Richard M ^a   DeHahn, Tammy B ^a   Kirmani, Kashif ^a   Spencer, Charles D ^a   Watkins, Scott A ^a   Considine, Eileen L ^a   Dempsey, Jack A ^a   Ogg, Catherine A ^a   Stamm, Nancy B ^a   Anderson, Bryan D ^a   Campbell, Robert M ^a   Vasudevan, Vasu ^a   Lytle, Michelle L ^a   more..

^a ELI LILLY AND COMPANY   (United States)

^b ELI LILLY AND COMPANY   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAZOLE DERIVATIVE; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR; RETINOBLASTOMA PROTEIN; SERINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; PROTEIN PHOSPHORYLATION; STRUCTURE ACTIVITY RELATION;

EID: 12444308937     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00461-X     Document Type: Article

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