메뉴 건너뛰기




Volumn 73, Issue 4, 1998, Pages 365-371

What has the cloning of the ATM gene told us about ataxia telangiectasia?

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE; PROTEIN P53;

EID: 0031953837     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530098142185     Document Type: Conference Paper
Times cited : (22)

References (57)
  • 1
    • 0030482567 scopus 로고    scopus 로고
    • Molecular genotyping shows that ataxia telangiectasia heterozygotes are predisposed to breast cancer
    • ATHMA, P., RAPPAPORT, R. and SWIFT, M., 1996, Molecular genotyping shows that ataxia telangiectasia heterozygotes are predisposed to breast cancer. Cancer Gienetics and Cytogenetics, 42, 130-134.
    • (1996) Cancer Gienetics and Cytogenetics , vol.42 , pp. 130-134
    • Athma, P.1    Rappaport, R.2    Swift, M.3
  • 3
    • 0030925565 scopus 로고    scopus 로고
    • Ataxia telangiectasia mutant protein activates c-Abl tyrosinc kinase in response to ionizing radiation
    • BASKARAN, R., WOOD, L. D., WHITTAKER, L. L., et al., 1997, Ataxia telangiectasia mutant protein activates c-Abl tyrosinc kinase in response to ionizing radiation. Nature, 387, 516-519.
    • (1997) Nature , vol.387 , pp. 516-519
    • Baskaran, R.1    Wood, L.D.2    Whittaker, L.L.3
  • 4
    • 0028213350 scopus 로고
    • Radiosensitivity in ataxia telangiectasia: Anomalies in radiation induced cell cycle delay
    • BEAMISH, H. and LAVIN, M. F., 1994, Radiosensitivity in ataxia telangiectasia: anomalies in radiation induced cell cycle delay. International Journal of Radiation Biology, 65, 175-184.
    • (1994) International Journal of Radiation Biology , vol.65 , pp. 175-184
    • Beamish, H.1    Lavin, M.F.2
  • 9
    • 0030476720 scopus 로고    scopus 로고
    • The product of the ATM gene is a 370kDa nuclear phosphoprotein
    • CHEN, G. and LEE, E.-H., 1996, The product of the ATM gene is a 370kDa nuclear phosphoprotein. Journal of Biological Chemistry, 271, 33 693-33 697.
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 33693-33697
    • Chen, G.1    Lee, E.-H.2
  • 13
    • 0029987944 scopus 로고    scopus 로고
    • Deregulated apoptosis in ataxia telangiectasia; association with clinical stigmata and radiosensitivity
    • DUCHAUD, E., RIDET, A., STOPPA-LYONNET, D., JANIN, N., MOUSTACCHI, E. and ROSSELLI, F., 1996, Deregulated apoptosis in ataxia telangiectasia; association with clinical stigmata and radiosensitivity. Cancer Research, 56, 1400-1404.
    • (1996) Cancer Research , vol.56 , pp. 1400-1404
    • Duchaud, E.1    Ridet, A.2    Stoppa-Lyonnet, D.3    Janin, N.4    Moustacchi, E.5    Rosselli, F.6
  • 17
    • 13344269672 scopus 로고    scopus 로고
    • Predominance of null mutations in ataxia-telangiectasia
    • GILAD, S., KHORSAVI, R., SHKEDY, D., et al., 1996, Predominance of null mutations in ataxia-telangiectasia. Human Molecular Genetics, 5, 433-439.
    • (1996) Human Molecular Genetics , vol.5 , pp. 433-439
    • Gilad, S.1    Khorsavi, R.2    Shkedy, D.3
  • 18
    • 0029088371 scopus 로고
    • TEL1, a gene involved in controlling telomere length in S. cerevisiae is homologous to the human ataxia telangiectasia gene
    • GREENWELL, P. W., KRONMAL, S. L., PORTER, S. E., GASSENHUBER, J., OBERMAIER, B. and PETES, T. D., 1995, TEL1, a gene involved in controlling telomere length in S. cerevisiae is homologous to the human ataxia telangiectasia gene. Cell, 82, 823-829.
    • (1995) Cell , vol.82 , pp. 823-829
    • Greenwell, P.W.1    Kronmal, S.L.2    Porter, S.E.3    Gassenhuber, J.4    Obermaier, B.5    Petes, T.D.6
  • 19
    • 0029156599 scopus 로고
    • DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product
    • HARTLEY, K. O., GELL, D., SMITH, G. C. M., ZHANG, H., DIVECHA, N., CONELLY, M., ADMON, A., LEES-MILLER, S. P., ANDERSON, C. W. and JACKSON, S. P., 1995, DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. Cell, 82, 849-856.
    • (1995) Cell , vol.82 , pp. 849-856
    • Hartley, K.O.1    Gell, D.2    Smith, G.C.M.3    Zhang, H.4    Divecha, N.5    Conelly, M.6    Admon, A.7    Lees-Miller, S.P.8    Anderson, C.W.9    Jackson, S.P.10
  • 22
    • 0028953951 scopus 로고
    • DNA dependent kinase (p350) is a candidate for murine scid defect
    • KIRCHGESSNER, C. U., PATIL, C. K., EVANS, J. W., CARTER, T. and BROWN, J. M., 1995, DNA dependent kinase (p350) is a candidate for murine scid defect. Science, 267, 1178-1182.
    • (1995) Science , vol.267 , pp. 1178-1182
    • Kirchgessner, C.U.1    Patil, C.K.2    Evans, J.W.3    Carter, T.4    Brown, J.M.5
  • 23
    • 10244227923 scopus 로고    scopus 로고
    • The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes
    • KEEGAN, K. S., HOLTZMAN, D. A., PLUG, A. W., et al., 1996, The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes. Genes and Development, 10, 2423-2437.
    • (1996) Genes and Development , vol.10 , pp. 2423-2437
    • Keegan, K.S.1    Holtzman, D.A.2    Plug, A.W.3
  • 25
    • 0024987973 scopus 로고
    • Hybrid T cell receptor genes formed by interlocus recombination in normal and ataxia telangiectasia lymphocytes
    • LIPKOWITZ, S., STERN, M.-H. and KIRSCH, I. R., 1990, Hybrid T cell receptor genes formed by interlocus recombination in normal and ataxia telangiectasia lymphocytes. Journal of Experimental Medicine, 172, 409-418.
    • (1990) Journal of Experimental Medicine , vol.172 , pp. 409-418
    • Lipkowitz, S.1    Stern, M.-H.2    Kirsch, I.R.3
  • 26
    • 0027332996 scopus 로고
    • Differential induction of transcriptionally active p53 following UV or ionising radiation; defects in chromosome instability syndromes?
    • LY, X. and LANF., D. P., 1993, Differential induction of transcriptionally active p53 following UV or ionising radiation; defects in chromosome instability syndromes? Cell, 75, 765-778.
    • (1993) Cell , vol.75 , pp. 765-778
    • Ly, X.1    Lanf, D.P.2
  • 27
    • 0030052137 scopus 로고    scopus 로고
    • From DNA damage to cell cycle arrest and suicide: A budding yeast perspective
    • LYDALL, D. and WEINERT, T., 1996, From DNA damage to cell cycle arrest and suicide: a budding yeast perspective. Current Opinion in Genetics and Development, 6, 4-11.
    • (1996) Current Opinion in Genetics and Development , vol.6 , pp. 4-11
    • Lydall, D.1    Weinert, T.2
  • 30
    • 0028880649 scopus 로고
    • Ataxia telangiectasia and cellular responses to DNA damage
    • MEYN, M. S., 1995, Ataxia telangiectasia and cellular responses to DNA damage. Cancer Research, 55, 5991-6001.
    • (1995) Cancer Research , vol.55 , pp. 5991-6001
    • Meyn, M.S.1
  • 33
    • 0029150855 scopus 로고
    • TEL1, a Saccharomyces cervisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1
    • MORROW, D. M., TAGLE, D. M., SHILOH, Y., COLLINS, F. S. and HIETER, P., 1995, TEL1, a Saccharomyces cervisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1. Cell, 82, 831-840.
    • (1995) Cell , vol.82 , pp. 831-840
    • Morrow, D.M.1    Tagle, D.M.2    Shiloh, Y.3    Collins, F.S.4    Hieter, P.5
  • 35
    • 0030593033 scopus 로고    scopus 로고
    • Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways
    • SANCHEZ, Y., DESANY, B. A., JONES, W. J., LIU, Q., WANG, B. and ELLEDGE, S. J., 1996, Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways. Science, 271, 357-360.
    • (1996) Science , vol.271 , pp. 357-360
    • Sanchez, Y.1    Desany, B.A.2    Jones, W.J.3    Liu, Q.4    Wang, B.5    Elledge, S.J.6
  • 36
    • 0029057336 scopus 로고
    • A single ataxia telangiectasia gene with a product similar to PI-3 kinase
    • SAVITSKY, K., BAR-SHIRA, A., GILAD, S., ROTMAN, G., ZIV, Y., VANAGAITE, L., TAGLE, D. A., et al., 1995a, A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science, 268, 1749-1753.
    • (1995) Science , vol.268 , pp. 1749-1753
    • Savitsky, K.1    Bar-Shira, A.2    Gilad, S.3    Rotman, G.4    Ziv, Y.5    Vanagaite, L.6    Tagle, D.A.7
  • 37
    • 0028827312 scopus 로고
    • The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species
    • SAVITSKY, K., SFEZ, S., TAGLE, D. A., ZIV, Y., SARTIEL, A., SHILOH, Y. and ROTMAN, G., 1995b, The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species. Human Molecular Genetics, 4, 2025-2032.
    • (1995) Human Molecular Genetics , vol.4 , pp. 2025-2032
    • Savitsky, K.1    Sfez, S.2    Tagle, D.A.3    Ziv, Y.4    Sartiel, A.5    Shiloh, Y.6    Rotman, G.7
  • 39
    • 0030992749 scopus 로고    scopus 로고
    • Interaction between ATM protein and c-Abl in response to DNA damage
    • SHAFMAN, T., KHANNA, K. K., KEDAR, P., et al., 1997, Interaction between ATM protein and c-Abl in response to DNA damage. Nature, 387, 520-523.
    • (1997) Nature , vol.387 , pp. 520-523
    • Shafman, T.1    Khanna, K.K.2    Kedar, P.3
  • 41
    • 0026409331 scopus 로고
    • Incidence of cancer in 161 families affected by ataxia-telangiectasia
    • SWIFT, M., MORRELL, D., MASSEY, R. B. and CHASE, C. L., 1991, Incidence of cancer in 161 families affected by ataxia-telangiectasia. New England Journal of Medicine, 325, 1831-1836.
    • (1991) New England Journal of Medicine , vol.325 , pp. 1831-1836
    • Swift, M.1    Morrell, D.2    Massey, R.B.3    Chase, C.L.4
  • 45
    • 0002845437 scopus 로고    scopus 로고
    • Malignant disease and variations in radiosensitivity in ataxia telangiectasia patients
    • edited by R. A. Eeles, B. A. J. Ponder, D. F. Easton and D. Horwich (London: Chapman and Hall)
    • TAYLOR, A. M. R., HERNANDEZ, D., MCCONVILLE, C. M., WOODS, C. G., STAGEY, M., BIGGS, P., BYRD, P. J., ARLETT, C. F. and SCOTT, D. 1996b, Malignant disease and variations in radiosensitivity in ataxia telangiectasia patients. In Genetic Predisposition to Cancer, edited by R. A. Eeles, B. A. J. Ponder, D. F. Easton and D. Horwich (London: Chapman and Hall), pp. 138-151.
    • (1996) Genetic Predisposition to Cancer , pp. 138-151
    • Taylor, A.M.R.1    Hernandez, D.2    Mcconville, C.M.3    Woods, C.G.4    Stagey, M.5    Biggs, P.6    Byrd, P.J.7    Arlett, C.F.8    Scott, D.9
  • 46
    • 0030051855 scopus 로고    scopus 로고
    • Leukaemia and lymphoma in ataxia telangiectasia
    • TAYLOR, A. M. R., METCALFE, J. A., THICK, J. and MAK, Y. F., 1996a, Leukaemia and lymphoma in ataxia telangiectasia. Blood, 87, 423-438.
    • (1996) Blood , vol.87 , pp. 423-438
    • Taylor, A.M.R.1    Metcalfe, J.A.2    Thick, J.3    Mak, Y.F.4
  • 51
    • 8244245266 scopus 로고    scopus 로고
    • Cellular localisation of the ataxia telangiectasia (ATM) gene product and discrimination between mutated and normal forms
    • WATTERS, D., KHANNA, K. K., BEAMISH, H., et al., 1997, Cellular localisation of the ataxia telangiectasia (ATM) gene product and discrimination between mutated and normal forms. Oncogene, 14, 1911-1921.
    • (1997) Oncogene , vol.14 , pp. 1911-1921
    • Watters, D.1    Khanna, K.K.2    Beamish, H.3
  • 52
    • 0030879563 scopus 로고    scopus 로고
    • atm and p53 cooperate in apoptosis and suppression of tumorigenesis but not in resistance to acute radiation toxicity
    • WESTPHAL, C. H., ROWAN, S., SCHMALTZ, C., ELSON, A., FISHER, D. E. and LEDER, P., 1997, atm and p53 cooperate in apoptosis and suppression of tumorigenesis but not in resistance to acute radiation toxicity. Nature Genetics, 16, 397-401.
    • (1997) Nature Genetics , vol.16 , pp. 397-401
    • Westphal, C.H.1    Rowan, S.2    Schmaltz, C.3    Elson, A.4    Fisher, D.E.5    Leder, P.6
  • 54
    • 0029844048 scopus 로고    scopus 로고
    • Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects and thymic lymphoma
    • XU, Y., ASHLEY, T., BRAINERD, E. E., BRONSON, R. T., MEYN, M. S. and BALTIMORE, D., 1996, Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects and thymic lymphoma. Genes and Development, 10, 2411-2422.
    • (1996) Genes and Development , vol.10 , pp. 2411-2422
    • Xu, Y.1    Ashley, T.2    Brainerd, E.E.3    Bronson, R.T.4    Meyn, M.S.5    Baltimore, D.6
  • 55
    • 0029821651 scopus 로고    scopus 로고
    • Dual roles of ATM in the cellular response to radiation and in cell growth response
    • XU, Y. and BALTIMORE, D., 1996, Dual roles of ATM in the cellular response to radiation and in cell growth response. Genes and Development, 10, 2401-2410.
    • (1996) Genes and Development , vol.10 , pp. 2401-2410
    • Xu, Y.1    Baltimore, D.2
  • 56
    • 0029973738 scopus 로고    scopus 로고
    • Role of c-Abl tyrosine kinase in growth arrest response to DNA damage
    • YUAN, Z.-M., 1996, Role of c-Abl tyrosine kinase in growth arrest response to DNA damage. Nature, 382, 272-274.
    • (1996) Nature , vol.382 , pp. 272-274
    • Yuan, Z.-M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.