Synthesis of syn- and anti-1-amino-3-[18 F]fluoromethyl-cyclobutane-1-carboxylic acid (FMACBC), potential PET ligands for tumor detection

Journal of Medicinal Chemistry

Volumn 45, Issue 11, 2002, Pages 2250-2259

  Martarello, Laurent ^a   McConathy, Jonathan ^a   Camp, Vernon M ^a   Malveaux, Eugene J ^a   Simpson, Nicholas E ^b   Simpson, Chiab P ^b   Olson, Jeffrey J ^b   Bowers, Geoffrey D ^b   Goodman, Mark M ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 AMINO 3 FLUOROMETHYL CYCLOBUTANE 1 CARBOXYLIC ACID F 18; FLUORINE 18; UNCLASSIFIED DRUG;

AMINO ACID TRANSPORT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TUMOR; CONTROLLED STUDY; DRUG SYNTHESIS; GLIOSARCOMA; ISOTOPE LABELING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOACTIVITY; RADIOCHEMISTRY; RAT; RAT STRAIN; TUMOR DIAGNOSIS;

AMINO ACID TRANSPORT SYSTEM A; AMINO ACID TRANSPORT SYSTEM L; AMINO ACIDS; ANIMALS; BRAIN; BRAIN NEOPLASMS; CARBOXYLIC ACIDS; CRYSTALLOGRAPHY, X-RAY; CYCLOBUTANES; FLUORINE RADIOISOTOPES; GLIOSARCOMA; ISOTOPE LABELING; LIGANDS; MALE; NEOPLASM TRANSPLANTATION; PROPIONIC ACIDS; RADIOPHARMACEUTICALS; RATS; RATS, INBRED F344; STEREOISOMERISM; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED; TUMOR CELLS, CULTURED;

EID: 0037161594     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010242p     Document Type: Article

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