Hypoxia inhibits amino acid uptake in human lung fibroblasts

Journal of Applied Physiology

Volumn 89, Issue 4, 2000, Pages 1425-1431

  Berk, John L ^a,b   Hatch, Christine A ^a   Goldstein, Ronald H ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Pulmonary Center   (United States)

Author keywords

Amino acid uptake; Hypoxia; Lung fibroblasts; Type I collagen

Indexed keywords

2 AMINO 2 METHYLPROPIONIC ACID; 2 METHYL 2 METHYLAMINOPROPIONIC ACID; AMINO ACID; COLLAGEN TYPE 1; CYCLOHEXIMIDE; INDOMETACIN; PROLINE;

AMINO ACID TRANSPORT; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYPOXIA; LUNG FIBROBLAST; OXYGEN TENSION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN SYNTHESIS; TRANSPORT KINETICS;

EID: 0033770994     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.2000.89.4.1425     Document Type: Article

References (42)

1. Relationship of alveolar epithelial injury and repair to the induction of pulmonary fibrosis
2. 1, thyroid hormone, angiotensin II and basic fibroblast growth factor
3. Hypoxia downregulates tropoelastin gene expression in rat lung fibroblasts by pretranslational mechanisms
4. Serotonin transport in reconstituted endothelial cell plasma membrane proteoliposomes: Effect of hypoxia
5. Hypoxia inhibits L-arginine uptake by pulmonary artery endothelial cells
6. A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels
7. Effects of acute and chronic hypoxia on rat lung cyclooxygenase
8. 2 and progesterone on rat brain synaptosomal plasma membranes
9. 2+-stimulated ATPase of Walker-256 tumor microsomal membranes
10. Transport and metabolism of L-glutamate during oxygenation, anoxia, and reoxygenation of rat cardiac myocytes
11. 1(I) procollagen in human dermal fibroblasts
12. 2
13. 2 on transforming growth factor-β and insulin-induced collagen formation in lung fibroblasts
14. The accumulation of type I collagen mRNAs in human embryonic lung fibroblasts stimulated by transforming growth factor-β
15. Adaptive increase of amino acid transport system A requires ERK1/2 activation
16. 2) on amino acid uptake and protein formation by lung fibroblasts
17. Effect of prolonged prostaglandin exposure on prostaglandin synthesis by human lung fibroblasts
18. Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice
19. Characterization of L-glutamine transport by pulmonary artery endothelial cells
20. Cloning of rat asparagine synthetase and specificity of the amino acid-dependent control of its mRNA content
21. Specific and non-specific alterations in membrane microviscosity induced by retinoids in embryonal carcinoma and fibroblast cells
22. Amino acid-regulated gene expression in eukaryotic cells
23. Effects of hypoxia on the extracellular matrix production of cultured rat mesangial cells
24. Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia
25. The effect of retinoic acid on amino acid uptake and protein synthesis by lung fibroblasts
26. Retinoic acid-induced inhibition of type I collagen gene expression by human lung fibroblasts
27. Regulation of type I collagen mRNA by amino acid deprivation in human lung fibroblasts
28. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
29. Regulatory and molecular aspects of mammalian amino acid transport
30. The matrix metalloproteinases and their inhibitors
31. Epithelial necrosis and alveolar collapse in the pathogenesis of usual interstitial pneumonia
32. Regulation of type I collagen mRNA in lung fibroblasts by cystine availability
33. Molecular cloning of an amino acid-regulated mRNA (amino acid starvation-induced) in rat hepatoma cells
34. Neutral amino acid transport systems in Chinese hamster ovary cells
35. The regulation of neutral amino acid transport in mammalian cells
36. Proline metabolism in cartilage: The importance of proline biosynthesis
37. Repair of elastase-digested elastic fibers in acellular matrices by replating with neonatal rat-lung lipid interstitial fibroblasts or other elastogenic cell types
38. Hypoxia inhibits L-arginine synthesis from L-citrulline in porcine pulmonary artery endothelial cells
39. Osmoregulation of amino acid transport activity in cultured fibroblasts
40. Electron spin resonance study of the interactions of retinoids with a phospholipid model membrane
41. Simultaneous regulation of amino acid influx and efflux by system A in the hepatoma cell HTC. Ouabain simulates the starvation-induced derepression of system A amino acid transport