메뉴 건너뛰기




Volumn 68, Issue 3, 1997, Pages 954-960

Identification of a system N-like Na+-dependent glutamine transport activity in rat brain neurons

Author keywords

Amino acids; Asparagine; Glutamate; Neurotransmitters

Indexed keywords

2 METHYL 2 METHYLAMINOPROPIONIC ACID; ASPARAGINE; GLUTAMINE; HISTIDINE; SODIUM ION; THREONINE;

EID: 0031024393     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.68030954.x     Document Type: Article
Times cited : (53)

References (48)
  • 2
    • 0027327563 scopus 로고
    • Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family
    • Arriza J. L., Kavanaugh M. P., Fairman W. A., Wu Y. N., Murdoch G. H., North R. A., and Amara S. G. (1993) Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family. J. Biol. Chem. 268, 15329-15332.
    • (1993) J. Biol. Chem. , vol.268 , pp. 15329-15332
    • Arriza, J.L.1    Kavanaugh, M.P.2    Fairman, W.A.3    Wu, Y.N.4    Murdoch, G.H.5    North, R.A.6    Amara, S.G.7
  • 3
    • 0016115832 scopus 로고
    • Uptake and release of possible false transmitter amino acids in rat CNS structural elements. I. Glutamate and related amino acids
    • Baldessarini R. J. and Yorke C. (1974) Uptake and release of possible false transmitter amino acids in rat CNS structural elements. I. Glutamate and related amino acids. J. Neurochem. 23, 839-848.
    • (1974) J. Neurochem. , vol.23 , pp. 839-848
    • Baldessarini, R.J.1    Yorke, C.2
  • 4
    • 0018870520 scopus 로고
    • Kinetics of cerebral uptake processes in vitro of L-glutamine, branched-chain L-amino acids, and L-phenylalanine: Effects of ouabain
    • Benjamin A. M., Verjee Z. H., and Quastel J. H. (1980) Kinetics of cerebral uptake processes in vitro of L-glutamine, branched-chain L-amino acids, and L-phenylalanine: effects of ouabain. J. Neurochem. 35, 67-77.
    • (1980) J. Neurochem. , vol.35 , pp. 67-77
    • Benjamin, A.M.1    Verjee, Z.H.2    Quastel, J.H.3
  • 6
    • 0001594597 scopus 로고
    • The use of N-methylation to direct the route of mediated transport of amino acids
    • Christensen H. N., Oxender D. L., Liang M., and Vatz K. A. (1965) The use of N-methylation to direct the route of mediated transport of amino acids. J. Biol. Chem. 240, 3609-3616.
    • (1965) J. Biol. Chem. , vol.240 , pp. 3609-3616
    • Christensen, H.N.1    Oxender, D.L.2    Liang, M.3    Vatz, K.A.4
  • 7
    • 0027604913 scopus 로고
    • Amino acid neurotransmitter transporters: Structure, function, and molecular diversity
    • Clark J. A. and Amara S. G. (1993) Amino acid neurotransmitter transporters: structure, function, and molecular diversity. Bioessays 15, 323-332.
    • (1993) Bioessays , vol.15 , pp. 323-332
    • Clark, J.A.1    Amara, S.G.2
  • 8
    • 0026699334 scopus 로고
    • + L) in human erythrocytes that recognizes lysine and leucine with high affinity
    • + L) in human erythrocytes that recognizes lysine and leucine with high affinity. J. Physiol. (Lond.) 454, 491-501.
    • (1992) J. Physiol. (Lond.) , vol.454 , pp. 491-501
    • Deves, R.1    Chavez, P.2    Boyd, C.A.R.3
  • 9
    • 0025196959 scopus 로고
    • Metabolism and role of glutamate in mammalian brain
    • Erecińska M. and Silver I. A. (1990) Metabolism and role of glutamate in mammalian brain. Prog. Neurobiol. 35, 245-296.
    • (1990) Prog. Neurobiol. , vol.35 , pp. 245-296
    • Erecińska, M.1    Silver, I.A.2
  • 10
    • 0025880073 scopus 로고
    • Transport of asparagine by rat brain synaptosomes: An approach to evaluate glutamine accumulation
    • Erecińska M., Zaleska M. M., Chiu L., and Nelson D. (1991) Transport of asparagine by rat brain synaptosomes: an approach to evaluate glutamine accumulation. J. Neurochem. 57, 491-498.
    • (1991) J. Neurochem. , vol.57 , pp. 491-498
    • Erecińska, M.1    Zaleska, M.M.2    Chiu, L.3    Nelson, D.4
  • 11
    • 0028343853 scopus 로고
    • Cerebral alanine transport and alanine aminotransferase reaction: Alanine as a source of neuronal glutamate
    • Erecińska M., Nelson D., Nissim I., Daikhin Y., and Yudkoff M. (1994) Cerebral alanine transport and alanine aminotransferase reaction: alanine as a source of neuronal glutamate. J. Neurochem. 62, 1953-1964.
    • (1994) J. Neurochem. , vol.62 , pp. 1953-1964
    • Erecińska, M.1    Nelson, D.2    Nissim, I.3    Daikhin, Y.4    Yudkoff, M.5
  • 12
    • 0026716689 scopus 로고
    • Molecular cloning and expression of a high affinity L-proline transporter expressed in putative glutamatergic pathways of rat brain
    • Fremeau R. T., Caron M. G., and Blakely R. D. (1992) Molecular cloning and expression of a high affinity L-proline transporter expressed in putative glutamatergic pathways of rat brain. Neuron 8, 915-926.
    • (1992) Neuron , vol.8 , pp. 915-926
    • Fremeau, R.T.1    Caron, M.G.2    Blakely, R.D.3
  • 13
    • 0019809188 scopus 로고
    • Surprising differences in substrate selectivity and other properties of systems A and ASC between rat hepatocytes and the hepatoma cell line HTC
    • Handlogten M. E., Garcia-Canero R., Lancaster K. T., and Christensen H. N. (1981) Surprising differences in substrate selectivity and other properties of systems A and ASC between rat hepatocytes and the hepatoma cell line HTC. J. Biol. Chem. 256, 7905-7909.
    • (1981) J. Biol. Chem. , vol.256 , pp. 7905-7909
    • Handlogten, M.E.1    Garcia-Canero, R.2    Lancaster, K.T.3    Christensen, H.N.4
  • 14
    • 0018872055 scopus 로고
    • Absence of preferential glutamine uptake into neurons - An indication of a net transfer of TCA constituents from nerve ending to astrocytes?
    • Hertz L., Yu A., Svenneby G., Kvamme E., Fosmark H., and Schousboe A. (1980) Absence of preferential glutamine uptake into neurons - an indication of a net transfer of TCA constituents from nerve ending to astrocytes? Neurosci. Lett. 16, 103-109.
    • (1980) Neurosci. Lett. , vol.16 , pp. 103-109
    • Hertz, L.1    Yu, A.2    Svenneby, G.3    Kvamme, E.4    Fosmark, H.5    Schousboe, A.6
  • 15
    • 0023571527 scopus 로고
    • Characteristics of L-glutamine transport in perfused rat skeletal muscle
    • Hundal H. S., Rennie M. J., and Watt P. W. (1987) Characteristics of L-glutamine transport in perfused rat skeletal muscle. J. Physiol. (Lond.) 393, 283-305.
    • (1987) J. Physiol. (Lond.) , vol.393 , pp. 283-305
    • Hundal, H.S.1    Rennie, M.J.2    Watt, P.W.3
  • 16
    • 0018249827 scopus 로고
    • Characteristics of the transport of alanine, serine and glutamine across the plasma membrane of isolated rat liver cells
    • Joseph S. K., Bradford M. M., and McGivan J. D. (1978) Characteristics of the transport of alanine, serine and glutamine across the plasma membrane of isolated rat liver cells. Biochem. J. 176, 827-836.
    • (1978) Biochem. J. , vol.176 , pp. 827-836
    • Joseph, S.K.1    Bradford, M.M.2    McGivan, J.D.3
  • 17
    • 0028535152 scopus 로고
    • Structure, function and brain localization of neurotransmitter transporters
    • Jursky F., Tamura S., Tamura A., Mandiyan S., Nelson H., and Nelson N. (1995) Structure, function and brain localization of neurotransmitter transporters. J. Exp. Biol. 196, 283-295.
    • (1995) J. Exp. Biol. , vol.196 , pp. 283-295
    • Jursky, F.1    Tamura, S.2    Tamura, A.3    Mandiyan, S.4    Nelson, H.5    Nelson, N.6
  • 18
    • 0026458124 scopus 로고
    • Primary structure and functional characterization of a high-affinity glutamate transporter
    • Kanai Y. and Hediger M. A. (1992) Primary structure and functional characterization of a high-affinity glutamate transporter. Nature 360, 467-471.
    • (1992) Nature , vol.360 , pp. 467-471
    • Kanai, Y.1    Hediger, M.A.2
  • 19
    • 0027136017 scopus 로고
    • A new family of neurotransmitter transporter: The high-affinity glutamate transporters
    • Kanai Y., Smith C. P., and Hediger M. A. (1995) A new family of neurotransmitter transporter: the high-affinity glutamate transporters. FASEB J. 7, 1450-1459.
    • (1995) FASEB J. , vol.7 , pp. 1450-1459
    • Kanai, Y.1    Smith, C.P.2    Hediger, M.A.3
  • 20
    • 0027289528 scopus 로고
    • Glutamate transporters from brain: A novel neurotransmitter transporter family
    • Kanner B. I. (1993) Glutamate transporters from brain: a novel neurotransmitter transporter family. FEBS Lett. 325, 95-99.
    • (1993) FEBS Lett. , vol.325 , pp. 95-99
    • Kanner, B.I.1
  • 21
    • 0028803353 scopus 로고
    • N-system amino acid transport at the blood-CSF barrier
    • Keep R. F. and Xiang J. (1995) N-system amino acid transport at the blood-CSF barrier. J. Neurochem. 65, 2571-2576.
    • (1995) J. Neurochem. , vol.65 , pp. 2571-2576
    • Keep, R.F.1    Xiang, J.2
  • 22
    • 0024429124 scopus 로고
    • Measurement of amino acid transport by hepatocytes in suspension or monolayer culture
    • Kilberg M. S. (1989) Measurement of amino acid transport by hepatocytes in suspension or monolayer culture. Methods Enzymol. 173, 564-575.
    • (1989) Methods Enzymol. , vol.173 , pp. 564-575
    • Kilberg, M.S.1
  • 23
    • 0019195152 scopus 로고
    • Characteristics of an amino acid transport system in rat liver for glutamine, asparagine, histidine, and closely related analogs
    • Kilberg M. S., Handlogten M. E., and Christensen H. N. (1980) Characteristics of an amino acid transport system in rat liver for glutamine, asparagine, histidine, and closely related analogs. J. Biol. Chem. 255, 4011-4019.
    • (1980) J. Biol. Chem. , vol.255 , pp. 4011-4019
    • Kilberg, M.S.1    Handlogten, M.E.2    Christensen, H.N.3
  • 24
    • 0027239610 scopus 로고
    • Recent advances in mammalian amino acid transport
    • Kilberg M. S., Stevens B. R., and Novak D. (1993) Recent advances in mammalian amino acid transport. Annu. Rev. Nutr. 13, 137-165.
    • (1993) Annu. Rev. Nutr. , vol.13 , pp. 137-165
    • Kilberg, M.S.1    Stevens, B.R.2    Novak, D.3
  • 25
    • 1842352735 scopus 로고
    • Molecular cloning and expression of a human cDNA encoding system ASC amino acid transport activity
    • (Keppler D. and Jungermann K., eds), Kluwer Academic, Lancaster
    • Kilberg M. S., Tamarappoo B. K., Shafqat S., and Fremeau R. T. (1994) Molecular cloning and expression of a human cDNA encoding system ASC amino acid transport activity, in Transport in the Liver (Keppler D. and Jungermann K., eds), pp. 51-58. Kluwer Academic, Lancaster.
    • (1994) Transport in the Liver , pp. 51-58
    • Kilberg, M.S.1    Tamarappoo, B.K.2    Shafqat, S.3    Fremeau, R.T.4
  • 26
    • 0028534838 scopus 로고
    • +-type cationic amino acid transport: Expression and regulation of the mCAT genes
    • +-type cationic amino acid transport: expression and regulation of the mCAT genes. J. Exp. Biol. 196, 109-121.
    • (1994) J. Exp. Biol. , vol.196 , pp. 109-121
    • MacLeod, C.L.1    Finley, K.D.2    Kakuda, D.K.3
  • 27
    • 0028962660 scopus 로고
    • Amino acid transport by small intestinal, hepatic, and pancreatic epithelia
    • Mailliard M. E., Stevens B. R., and Mann G. E. (1995) Amino acid transport by small intestinal, hepatic, and pancreatic epithelia. Gastroenterology 108, 888-910.
    • (1995) Gastroenterology , vol.108 , pp. 888-910
    • Mailliard, M.E.1    Stevens, B.R.2    Mann, G.E.3
  • 28
    • 0020433156 scopus 로고
    • Hepatic transport system interconverted by protonation from service for neutral to service for anionic amino acids
    • Makowske M. and Christensen H. N. (1982) Hepatic transport system interconverted by protonation from service for neutral to service for anionic amino acids. J. Biol. Chem. 257, 14635-14638.
    • (1982) J. Biol. Chem. , vol.257 , pp. 14635-14638
    • Makowske, M.1    Christensen, H.N.2
  • 29
    • 0029892792 scopus 로고    scopus 로고
    • Molecular biology of mammalian amino acid transporters
    • Malandro M. S. and Kilberg M. S. (1996) Molecular biology of mammalian amino acid transporters. Annu. Rev. Biochem. 65, 305-336.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 305-336
    • Malandro, M.S.1    Kilberg, M.S.2
  • 30
    • 0028205533 scopus 로고
    • Regulatory and molecular aspects of mammalian amino acid transport
    • McGivan J. D. and Pastor-Anglada M. (1994) Regulatory and molecular aspects of mammalian amino acid transport. Biochem. J. 299, 321-334.
    • (1994) Biochem. J. , vol.299 , pp. 321-334
    • McGivan, J.D.1    Pastor-Anglada, M.2
  • 31
    • 0030005938 scopus 로고    scopus 로고
    • Glutamine transport in mouse cerebral astrocytes
    • Nagaraja T. N. and Brookes N. (1996) Glutamine transport in mouse cerebral astrocytes. J. Neurochem. 66, 1665-1674.
    • (1996) J. Neurochem. , vol.66 , pp. 1665-1674
    • Nagaraja, T.N.1    Brookes, N.2
  • 32
    • 0018382256 scopus 로고
    • Fine structural localization of glutamine synthetase in astrocytes of rat brain
    • Norenberg M. D. and Martinez-Hernandez A. (1979) Fine structural localization of glutamine synthetase in astrocytes of rat brain. Brain Res. 161, 303-310.
    • (1979) Brain Res. , vol.161 , pp. 303-310
    • Norenberg, M.D.1    Martinez-Hernandez, A.2
  • 34
    • 0019970123 scopus 로고
    • Glutamine and glutamate transport in cultured neuronal and glial cells
    • Ramaharobandro N., Borg J., Mandel P., and Mark J. (1982) Glutamine and glutamate transport in cultured neuronal and glial cells. Brain Res. 244, 113-121.
    • (1982) Brain Res. , vol.244 , pp. 113-121
    • Ramaharobandro, N.1    Borg, J.2    Mandel, P.3    Mark, J.4
  • 35
    • 0024458689 scopus 로고
    • High-affinity transport of L-glutamine by a plasma membrane preparation from rat brain
    • Roon R. J., Shofner S. A., and Koerner J. F. (1989) High-affinity transport of L-glutamine by a plasma membrane preparation from rat brain. Biochemistry 28, 8083-8087.
    • (1989) Biochemistry , vol.28 , pp. 8083-8087
    • Roon, R.J.1    Shofner, S.A.2    Koerner, J.F.3
  • 36
    • 0018695520 scopus 로고
    • Differences in glutamate uptake in astrocytes cultured from different brain regions
    • Schousboe A. and Divac I. (1979) Differences in glutamate uptake in astrocytes cultured from different brain regions. Brain Res. 177, 407-409.
    • (1979) Brain Res. , vol.177 , pp. 407-409
    • Schousboe, A.1    Divac, I.2
  • 37
    • 0018412111 scopus 로고
    • Inhibition pattern by analogs indicates the presence of ten or more transport systems for amino acids in brain cells
    • Sershen H. and Lajtha A. (1979) Inhibition pattern by analogs indicates the presence of ten or more transport systems for amino acids in brain cells. J. Neurochem. 32, 719-726.
    • (1979) J. Neurochem. , vol.32 , pp. 719-726
    • Sershen, H.1    Lajtha, A.2
  • 40
    • 0019991447 scopus 로고
    • Glutamine and alpha-ketoglutarate uptake and metabolism by nerve terminal enriched material from mouse cerebellum
    • Shank R. P. and Campbell G. L.-M. (1982) Glutamine and alpha-ketoglutarate uptake and metabolism by nerve terminal enriched material from mouse cerebellum. Neurochem. Res. 7, 601-616.
    • (1982) Neurochem. Res. , vol.7 , pp. 601-616
    • Shank, R.P.1    Campbell, G.L.-M.2
  • 41
    • 85051621265 scopus 로고
    • Angiotensin II receptor subtypes in neuronal cells
    • (Raizada M. K., Phillips M. I., and Sumners C., eds), CRC Press, Boca Raton, Florida
    • Sumners C. and Raizada M. K. (1993) Angiotensin II receptor subtypes in neuronal cells, in Cellular and Molecular Biology of Renin-Angiotensin System (Raizada M. K., Phillips M. I., and Sumners C., eds), pp. 379-411. CRC Press, Boca Raton, Florida.
    • (1993) Cellular and Molecular Biology of Renin-Angiotensin System , pp. 379-411
    • Sumners, C.1    Raizada, M.K.2
  • 42
    • 0030001740 scopus 로고    scopus 로고
    • Expressed human hippocampal ASCT1 amino acid transporter exhibits a pH-dependent change in substrate specificity
    • Tamarappoo B. K., McDonald K. K., and Kilberg M. S. (1996) Expressed human hippocampal ASCT1 amino acid transporter exhibits a pH-dependent change in substrate specificity. Biochim. Biophys. Acta 1279, 131-136.
    • (1996) Biochim. Biophys. Acta , vol.1279 , pp. 131-136
    • Tamarappoo, B.K.1    McDonald, K.K.2    Kilberg, M.S.3
  • 43
    • 0022386480 scopus 로고
    • +-dependent transport of basic, zwitterionic, and bicyclic amino acids by a broad-scope system in mouse blastocysts
    • +-dependent transport of basic, zwitterionic, and bicyclic amino acids by a broad-scope system in mouse blastocysts. J. Biol. Chem. 260, 12118-12123.
    • (1985) J. Biol. Chem. , vol.260 , pp. 12118-12123
    • Van Winkle, L.J.1    Christensen, H.N.2    Campione, A.L.3
  • 44
    • 0023850572 scopus 로고
    • + independent transport of basic and zwitterionic amino acids in mouse blastocysts by a shared system and by processes which distinguish between these substrates
    • + independent transport of basic and zwitterionic amino acids in mouse blastocysts by a shared system and by processes which distinguish between these substrates. J. Biol. Chem. 263, 3150-3163.
    • (1988) J. Biol. Chem. , vol.263 , pp. 3150-3163
    • Van Winkle, L.J.1    Campione, A.L.2    Gorman, J.M.3
  • 46
    • 0022478666 scopus 로고
    • Exogenous glutamate is metabolized to glutamine and exported by rat primary astrocyte cultures
    • Waniewski R. A. and Martin D. L. (1986) Exogenous glutamate is metabolized to glutamine and exported by rat primary astrocyte cultures. J. Neurochem. 47, 304-313.
    • (1986) J. Neurochem. , vol.47 , pp. 304-313
    • Waniewski, R.A.1    Martin, D.L.2
  • 47
    • 0018383602 scopus 로고
    • Studies of subcellular distribution of γ-aminobutyric acid and glutamic acid decarboxylase in mouse brain
    • Weiler C. T., Roberts E., and Kakefuda T. (1979) Studies of subcellular distribution of γ-aminobutyric acid and glutamic acid decarboxylase in mouse brain. J. Neurochem. 32, 559-565.
    • (1979) J. Neurochem. , vol.32 , pp. 559-565
    • Weiler, C.T.1    Roberts, E.2    Kakefuda, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.