Enrichment of yeast thioredoxin by green tea extract through activation of Yap1 transcription factor in Saccharomyces cerevisiae

Journal of Agricultural and Food Chemistry

Volumn 53, Issue 2, 2005, Pages 332-337

  Takatsume, Yoshifumi ^a   Maeta, Kazuhiro ^a   Izawa, Shingo ^a   Inoue, Yoshiharu ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Antioxidant; Catechin; Epigallocatechin gallate; Green tea extract; Polyphenol; Thioredoxin; Yap1; Yeast

Indexed keywords

GREEN TEA EXTRACT; POLYPHENOL; THIOREDOXIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR YAP1; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; GENE ACTIVATION; GENE EXPRESSION; NONHUMAN; OXIDATIVE STRESS; PROTEIN LOCALIZATION; REPORTER GENE; SACCHAROMYCES CEREVISIAE; WESTERN BLOTTING;

MEMBRANE PROTEINS; PHENOLS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; THIOREDOXIN; TRANSCRIPTION FACTORS;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 12344282174     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf048818h     Document Type: Article

References (51)

1. Meister, A. Glutathione-ascorbic acid antioxidant system in animals. J. Biol. Chem. 1994, 269, 9397-9400.
2. Vina, J.; Perez, C.; Furukawa, T.; Palacin, M.; Vina, J. R. Effect of oral glutathione on hepatic glutathione levels in rats and mice. Br. J. Nutr. 1989, 62, 683-691.
3. Vendemiale, G.; Grattagliano, I.; Altomare, E. An update on the role of free radicals and antioxidant defense in human disease. Int. J. Clin. Lab. Res. 1999, 29, 49-55.
4. Holmgren, A. Thioredoxin. Annu. Rev. Biochem. 1985, 54, 237-271.
5. Holmgren, A. Thioredoxin and glutaredoxin systems. J. Biol. Chem. 1989, 264, 13963-13966.
6. Dekigai, H.; Nakamura, H.; Bai, J.; Tanito, M.; Masutani, H.; Hirota, K.; Matsui, H.; Murakami, M.; Yodoi, J. Geranylgeranylacetone promotes induction and secretion of thioredoxin in gastric mucosal cells and peripheral blood lymphocytes. Free Radical Res. 2001, 35, 23-30.
7. del Val, G.; Yee, B. C.; Lozano, R. M.; Buchanan, B. B.; Ermel, R. W.; Lee, Y. M.; Frick, O. L. Thioredoxin treatment increases digestibility and lowers allergenicity of milk. J. Allergy Clin. Immunol. 1999, 103, 690-697.
8. Muller, E. G. Thioredoxin genes in Saccharomyces cerevisiae: map positions of TRX1 and TRX2. Yeast 1992, 8, 117-120.
9. Pedrajas, J. R.; Kosmidou, E.; Miranda-Vizuete, A.; Gustafsson, J. A.; Wright, A. P.; Spyrou, G. Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae. J. Biol. Chem. 1999, 274, 6366-6373.
10. Kuge, S.; Jones, N. YAP1 dependent activation of TRX2 is essential for the response of Saccharomyces cerevisiae to oxidative stress by hydroperoxides. EMBO J. 1994, 13, 655-664.
11. Morgan, B. A.; Banks, G. R.; Toone, W. M.; Raitt, D.; Kuge, S.; Johnston, L. H. The Skn7 response regulator controls gene expression in the oxidative stress response of the budding yeast Saccharomyces cerevisiae. EMBO J. 1997, 16, 1035-1044.
12. Frei, B.; Higdon, J. V. Antioxidant activity of tea polyphenols in vitro: evidence from animal studies. J. Nutr. 2003, 133, 3275S-3284S.
13. Higdon, J. V.; Frei, B. Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions. Crit. Rev. Food Sci. Nutr. 2003, 43, 89-143.
14. Rice-Evans, C. Plant polyphenols: free radical scavengers or chain-breaking antioxidants? Biochem. Soc. Symp. 1995, 61, 103-116.
15. Paquay, J. B.; Haenen, G. R.; Slender, G.; Wiseman, S. A.; Tijburg, L. B.; Bast, A. Protection against nitric oxide toxicity by tea. J. Agric. Food Chem. 2000, 48, 5768-5772.
16. Sarkar, A.; Bhaduri, A. Black tea is a powerful chemopreventor of reactive oxygen and nitrogen species: comparison with its individual catechin constituents and green tea. Biochem. Biophys. Res. Commun. 2001, 284, 173-178.
17. Chan, M.-M.; Fong, D.; Ho, C.-T.; Huang, H.-I. Inhibition of inducible nitric oxide synthase gene expression and enzyme activity by epigallocatechin gallate, a natural product from green tea. Biochem. Pharmacol. 1997, 54, 1281-1286.
18. Lin, Y.-L.; Lin, J.-K. (-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB. Mol. Pharmacol. 1997, 52, 465-472.
19. Inoue, Y.; Trevanichi, S.; Tsujimoto, Y.; Miki, T.; Miyabe, S.; Sugiyama, K.; Izawa, S.; Kimura, A. Evaluation of catechin and its derivative as antioxidant: recovery of growth arrest of Escherichia coli under oxidative conditions. J. Sci. Food Agric. 1996, 71, 297-300.
20. Arakawa, H.; Maeda, M.; Okubo, S.; Shimamura, T. Role of hydrogen peroxide in bactericidal action of catechin. Biol. Pharm. Bull. 2004, 27, 277-281.
21. Nakagawa, H.; Hasumi, K.; Woo, J. T.; Nagai, K.; Wachi, M. Generation of hydrogen peroxide primarily contributes to the induction of Fe(II)-dependent apoptosis in Jurkat cells by (-)-epigallocatechin gallate. Carcinogenesis 2004, Apr 16 [Epub ahead of print].
22. Tsuzi, D.; Maeta, K.; Takatsume, Y.; Izawa, S.; Inoue, Y. Regulation of the yeast phospholipid hydroperoxide glutathione peroxidase GPX2 by oxidative stress is mediated by Yap1 and Skn7. FEBS Lett. 2004, 565, 148-154.
23. Inoue, Y.; Trevanichi, S.; Fukuda, K.; Izawa, S.; Wakai, Y.; Kimura, A. Roles of esterase and alcohol acetyltransferase on production of isoamyl acetate in Hansenula mrakii. J. Agric. Food Chem. 1997, 45, 644-649.
24. Kuge, S.; Jones, N.; Nomoto, A. Regulation of yAP-1 nuclear localization in response to oxidative stress. EMBO J. 1997, 16, 1710-1720.
25. Wieser, R.; Adam, G.; Wagner, A.; Schüller, C.; Marchler, G.; Ruis, H.; Krawiec, Z.; Bilinski, T. Heat shock factor-independent heat control of transcription of the CTT1 gene encoding the cytosolic catalase T of Saccharomyces cerevisiae. J. Biol. Chem. 1991, 266, 12406-12411.
26. Inoue, Y.; Tsujimoto, Y.; Kimura, A. Expression of the glyoxalase I gene of Saccharomyces cerevisiae is regulated by high osmolarity glycerol mitogen-activated protein kinase pathway in osmotic stress response. J. Biol. Chem. 1998, 273, 2977-2983.
27. Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72, 248-254.
28. Izawa, S.; Maeda, K.; Sugiyama, K.; Mano, J.; Inoue, Y.; Kimura, A. Thioredoxin deficiency causes the constitutive activation of Yap1, an AP-1-like transcription factor in Saccharomyces cerevisiae. J. Biol. Chem. 1999, 274, 28459-28465.
29. Kudo, M.; Naito, Z.; Yokoyama, M.; Asano, G. Effects of quercetin and sunphenon on responses of cancer cells to heat shock damage. Exp. Mol. Pathol. 1999, 66, 66-75.
30. 2 sensing through oxidation of the Yap1 transcription factor. EMBO J. 2000, 19, 5157-5166.
31. Izawa, S.; Inoue, Y. A screening system for antioxidants using thioredoxin-deficient yeast: discovery of thermostable antioxidant activity from Agaricus blazei Murill. Appl. Microbiol. Biotechnol 2004, 64, 537-542.
32. Schnell, N.; Krems, B.; Entian, K. D. The PAR1 (YAP1/SNQ3) gene of Saccharomyces cerevisiae, a c-jun homologue, is involved in oxygen metabolism. Curr. Genet. 1992, 21, 269-273.
33. Lee, J.; Godon, C.; Lagniel, G.; Spector, D.; Garin, J.; Labarre, J.; Toledano, M. B. Yap1 and Skn7 control two specialized oxidative stress response regulons in yeast. J. Biol. Chem. 1999, 274, 16040-16046.
34. Krems, B.; Charizanis, C.; Entian, K. D. The response regulator-like protein Pos9/Skn7 of Saccharomyces cerevisiae is involved in oxidative stress resistance. Curr. Genet. 1996, 29, 327-334.
35. Fernandes, L.; Rodrigues-Pousada, C.; Struhl, K. Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions. Mol. Cell. Biol. 1997, 17, 6982-6993.
36. Inoue, Y.; Matsuda, T.; Sugiyama, K.; Izawa, S.; Kimura, A. Genetic analysis of glutathione peroxidase in oxidative stress response of Saccharomyces cerevisiae. J. Biol. Chem. 1999, 274, 27002-27009.
37. Winderickx, J.; de Winde, J. H.; Crauwels, M.; Hino, A.; Hohmann, S.; Van Dijck, P.; Thevelein, J. M. Regulation of genes encoding subunits of the trehalose synthase complex in Saccharomyces cerevisiae: novel variations of STRE-mediated transcription control? Mol. Gen. Genet. 1996, 252, 470-482.
38. Tran, L.-T.; Inoue, Y.; Kimura, A. Oxidative stress response in yeast: purification and some properties of a membrane-bound glutathione peroxidase from Hansenula mrakii. Biochim. Biophys. Acta 1993, 1164, 166-172.
39. Inoue, Y.; Tran, L.-T.; Kamakura, M.; Izawa, S.; Miki, T.; Tsujimoto, Y.; Kimura, A. Oxidative stress response in yeast: glutathione peroxidase of Hansenula mrakii is bound to the membrane of both mitochondria and cytoplasm. Biochim. Biophys. Acta 1995, 1245, 325-330.
40. Yang, C. S.; Maliakal, P.; Meng, X. Inhibition of carcinogenesis by tea. Annu. Rev. Pharmacol. Toxicol. 2002, 42, 25-54.
41. Nguyen, D. T.; Alarco, A. M.; Raymond, M. Multiple Yap1-binding sites mediate induction of the yeast major facilitator FLR1 gene in response to drugs, oxidants, and alkylating agents. J. Biol. Chem. 2001, 276, 1138-1145.
42. Wu, A. L.; Moye-Rowley, W. S. GSH1, which encodes γ- glutamylcysteine synthetase, is a target gene for yAP-1 transcriptional regulation. Mol. Cell. Biol. 1994, 14, 5832-5839.
43. Sugiyama, K.; Izawa, S.; Inoue, Y. The Yap1p-dependent induction of glutathione synthesis in heat shock response of Saccharomyces cerevisiae. J. Biol. Chem. 2000, 275, 15535-15540.
44. Sheweita, S. A.; Tilmisany, A. K. Cancer and phase II drug-metabolizing enzymes. Curr. Drug Metab. 2003, 4, 45-58.
45. Hayes, J. D.; Pulford, D. J. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit. Rev. Biochem. Mol. Biol. 1995, 30, 445-600.
46. Yu, R.; Jiao, J.-J.; Duh, J.-L.; Gudehithlu, K.; Tan, T.-H.; Kong, A.-N. Activation of mitogen-activated protein kinases by green tea polyphenols: potential signaling pathways in the regulation of antioxidant-responsive element-mediated phase II enzyme gene expression. Carcinogenesis 1997, 18, 451-456.
47. Chen, C.; Yu, R.; Owuor, E.-D.; Kong, A.-N. Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death. Arch. Pharm. Res. 2000, 23, 605-612.
48. Lin, Y.-L.; Cheng, C-Y.; Lin, Y.-P.; Lau, Y.-W.; Juan, I.-M.; Lin, J.-K. Hypolipidemic effect of green tea leaves through induction of antioxidant and phase II enzymes including superoxide dismutase, catalase, and glutathione-S-transferase in rats. J. Agric. Food Chem. 1998, 46, 1893-1899.
49. Jowsey, I. R.; Jiang, Q.; Itoh, K.; Yamamoto, M.; Hayes, J. D. Expression of the aflatoxin B1-8,9-epoxide-metabolizing murine glutathione S-transferase A3 subunit is regulated by the Nrf2 transcription factor through an antioxidant response element. Mol. Pharmacol. 2003, 64, 1018-1028.
50. Dhakshinamoorthy, S.; Jaiswal, A. K. c-Maf negatively regulates ARE-mediated detoxifying enzyme genes expression and anti-oxidant induction. Oncogene 2002, 21, 5301-5312.
51. Lee, S.-F.; Liang, Y.-C.; Lin, J.-K. Inhibition of 1,2,4-benzenetriol- generated active oxygen species and induction of phase II enzymes by green tea polyphenol. Chem. Biol. Interact. 1995, 95, 283-301.